pimethixene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2169 | 314-03-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | R06AX23 | RESPIRATORY SYSTEM ANTIHISTAMINES FOR SYSTEMIC USE ANTIHISTAMINES FOR SYSTEMIC USE Other antihistamines for systemic use |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.8 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Histone-lysine N-methyltransferase SETD7 | Enzyme | IC50 | 5.37 | CHEMBL | |||||
| 5-hydroxytryptamine receptor 2A | GPCR | Ki | 8.60 | CHEMBL | |||||
| Transcriptional activator protein luxR | Unclassified | IC50 | 4.25 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D07406 | KEGG_DRUG |
| C0071069 | UMLSCUI |
| CHEBI:94787 | CHEBI |
| CHEMBL152408 | ChEMBL_ID |
| DB13292 | DRUGBANK_ID |
| C004327 | MESH_SUPPLEMENTAL_RECORD_UI |
| 4822 | PUBCHEM_CID |
| 1739 | INN_ID |
| 13187-06-9 | SECONDARY_CAS_RN |
| T46J20J26F | UNII |
| 33712 | RXNORM |
| 005718 | NDDF |
| CHEMBL1523827 | ChEMBL_ID |
Pharmaceutical products:
None