Butyrylcholinesterase
Description:
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Drug Relations:
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donepezil
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An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE. | Bioactivity details | MOA |
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galantamine
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A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders. | Bioactivity details | MOA |
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hexafluronium
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curarimimetic agent for use with succinylcholine; muscle relaxant; structure; RN given refers to parent cpd | Bioactivity details | MOA |
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physostigmine
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A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity. | Bioactivity details | MOA |
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profenamine
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Bioactivity details | MOA |
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rivastigmine
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A carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON DISEASE. | Bioactivity details | MOA |
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tacrine
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A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. | Bioactivity details | MOA |
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velnacrine
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Bioactivity details | MOA |
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