insulin beef 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
5192 11070-73-8

Description:

MoleculeDescription

Synonyms:

  • insulin (beef)
  • insulin beef
  • insulin purified beef
  • insulin susp isophane beef
  • insulin susp isophane purified beef
  • insulin susp protamine zinc beef
  • insulin susp protamine zinc purified beef
  • insulin zinc susp beef
  • insulin zinc susp extended beef
  • insulin zinc susp extended purified beef
  • insulin zinc susp prompt beef
  • insulin zinc susp purified beef
  • Molecular weight: 5733.55
  • Formula: C254H377N65O75S6
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 2258.61
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
40 U P
40 U P
40 U P
40 U P

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hypoglycaemia 46.67 22.14 25 1947 69823 90556652
Toothache 44.06 22.14 17 1955 22213 90604262
Pharyngitis 40.73 22.14 16 1956 21931 90604544
Blood glucose increased 32.14 22.14 22 1950 95224 90531251
Blood aldosterone abnormal 29.09 22.14 4 1968 43 90626432
Gait inability 27.75 22.14 24 1948 146432 90480043
Diabetic metabolic decompensation 23.74 22.14 6 1966 1951 90624524

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hypoglycaemia 41.85 21.49 28 1786 59826 42559695
Hyperglycaemia 24.01 21.49 18 1796 45841 42573680

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hypoglycaemia 79.88 19.93 50 3817 116054 110469378
Hyperglycaemia 35.60 19.93 27 3840 85063 110500369
Toothache 35.31 19.93 17 3850 23558 110561874
Pharyngitis 31.36 19.93 16 3851 25082 110560350
Blood glucose increased 30.76 19.93 30 3837 132466 110452966
Blood aldosterone abnormal 27.19 19.93 4 3863 43 110585389
Acute myocardial infarction 25.33 19.93 22 3845 83755 110501677
Euglycaemic diabetic ketoacidosis 22.45 19.93 10 3857 11613 110573819
Acute kidney injury 21.01 19.93 59 3808 635371 109950061
Diabetic foot 20.38 19.93 7 3860 4088 110581344

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A10AB02 ALIMENTARY TRACT AND METABOLISM
DRUGS USED IN DIABETES
INSULINS AND ANALOGUES
Insulins and analogues for injection, fast-acting
ATC A10AC02 ALIMENTARY TRACT AND METABOLISM
DRUGS USED IN DIABETES
INSULINS AND ANALOGUES
Insulins and analogues for injection, intermediate-acting
ATC A10AD02 ALIMENTARY TRACT AND METABOLISM
DRUGS USED IN DIABETES
INSULINS AND ANALOGUES
Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting
ATC A10AE02 ALIMENTARY TRACT AND METABOLISM
DRUGS USED IN DIABETES
INSULINS AND ANALOGUES
Insulins and analogues for injection, long-acting
CHEBI has role CHEBI:35526 hypoglycemic agent

Related Drugs by ATC class:

A10AB Insulins and analogues for injection, fast-acting 5 drugs
insulin aspartinsulin glulisineinsulin humaninsulin lisproinsulin pork
A10AC Insulins and analogues for injection, intermediate-acting 3 drugs
insulin humaninsulin lisproinsulin pork
A10AD Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting 5 drugs
insulin aspartinsulin degludecinsulin humaninsulin lisproinsulin pork
A10AE Insulins and analogues for injection, long-acting 9 drugs
insulin degludecinsulin detemirinsulin glargineinsulin humaninsulin icodecinsulin porkliraglutidelixisenatidesemaglutide

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
576O9IZ534 UNII
C0304866 UMLSCUI
CHEBI:749473 CHEBI
CHEMBL1201629 ChEMBL_ID
16131099 PUBCHEM_CID
DB09456 DRUGBANK_ID
CHEMBL1201545 ChEMBL_ID
126208003 SNOMEDCT_US
4700006 SNOMEDCT_US
000867 NDDF
000868 NDDF

Pharmaceutical products:

None