Stem definition | Drug id | CAS RN |
---|---|---|
4981 | 116094-23-6 |
Molecule | Description |
---|---|
Synonyms:
|
Insulin that has been modified to contain an ASPARTIC ACID instead of a PROLINE at position 38 of the B-chain.
|
Dose | Unit | Route |
---|---|---|
40 | U | P |
40 | U | P |
40 | U | P |
None
Date | Agency | Company | Orphan |
---|---|---|---|
Sept. 20, 2019 | PMDA | Novo Nordisk Pharma Ltd. | |
Sept. 7, 1999 | EMA | NovoRapid | |
June 7, 2000 | FDA | NOVO NORDISK INC |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Diabetic ketoacidosis | 1392.54 | 10.81 | 550 | 46663 | 17322 | 50540589 |
Hypoglycaemia | 1212.60 | 10.81 | 704 | 46509 | 52877 | 50505034 |
Blood glucose increased | 1179.81 | 10.81 | 767 | 46446 | 70557 | 50487354 |
Blood glucose decreased | 402.46 | 10.81 | 236 | 46977 | 17975 | 50539936 |
Hyperglycaemia | 370.89 | 10.81 | 292 | 46921 | 36113 | 50521798 |
Diabetes mellitus inadequate control | 318.79 | 10.81 | 181 | 47032 | 12964 | 50544947 |
Ketoacidosis | 209.01 | 10.81 | 92 | 47121 | 3803 | 50554108 |
Glycosylated haemoglobin increased | 199.54 | 10.81 | 124 | 47089 | 10482 | 50547429 |
Diabetic retinopathy | 182.39 | 10.81 | 71 | 47142 | 2139 | 50555772 |
Hypoglycaemic unconsciousness | 161.76 | 10.81 | 49 | 47164 | 673 | 50557238 |
Blood glucose fluctuation | 160.23 | 10.81 | 78 | 47135 | 4068 | 50553843 |
Acute kidney injury | 158.46 | 10.81 | 520 | 46693 | 227538 | 50330373 |
Hypoglycaemic coma | 158.00 | 10.81 | 65 | 47148 | 2268 | 50555643 |
Product leakage | 153.84 | 10.81 | 44 | 47169 | 488 | 50557423 |
Drug ineffective | 138.16 | 10.81 | 356 | 46857 | 818977 | 49738934 |
Diabetic metabolic decompensation | 123.73 | 10.81 | 48 | 47165 | 1432 | 50556479 |
Blood glucose abnormal | 103.25 | 10.81 | 69 | 47144 | 6603 | 50551308 |
Drug intolerance | 102.77 | 10.81 | 38 | 47175 | 219066 | 50338845 |
Arthropathy | 93.79 | 10.81 | 17 | 47196 | 157889 | 50400022 |
Synovitis | 89.06 | 10.81 | 7 | 47206 | 123858 | 50434053 |
Systemic lupus erythematosus | 88.29 | 10.81 | 13 | 47200 | 140609 | 50417302 |
Contraindicated product administered | 84.34 | 10.81 | 18 | 47195 | 148940 | 50408971 |
Diabetic neuropathy | 83.16 | 10.81 | 48 | 47165 | 3543 | 50554368 |
Product quality issue | 83.05 | 10.81 | 122 | 47091 | 30736 | 50527175 |
Joint swelling | 82.32 | 10.81 | 65 | 47148 | 245221 | 50312690 |
Treatment failure | 81.34 | 10.81 | 15 | 47198 | 137622 | 50420289 |
Alopecia | 77.23 | 10.81 | 69 | 47144 | 244978 | 50312933 |
Infusion related reaction | 75.22 | 10.81 | 32 | 47181 | 169525 | 50388386 |
Glossodynia | 74.15 | 10.81 | 10 | 47203 | 115559 | 50442352 |
Hypoglycaemic seizure | 72.76 | 10.81 | 24 | 47189 | 441 | 50557470 |
Exposure during pregnancy | 72.54 | 10.81 | 263 | 46950 | 120752 | 50437159 |
Hyper IgE syndrome | 70.32 | 10.81 | 23 | 47190 | 411 | 50557500 |
Liquid product physical issue | 67.61 | 10.81 | 26 | 47187 | 757 | 50557154 |
Hypoglycaemia unawareness | 64.89 | 10.81 | 16 | 47197 | 94 | 50557817 |
Pain | 63.73 | 10.81 | 301 | 46912 | 578602 | 49979309 |
Arthralgia | 63.00 | 10.81 | 205 | 47008 | 438497 | 50119414 |
Diabetic ketosis | 60.49 | 10.81 | 17 | 47196 | 176 | 50557735 |
Rheumatoid arthritis | 58.05 | 10.81 | 62 | 47151 | 202488 | 50355423 |
Anti-insulin antibody positive | 57.41 | 10.81 | 14 | 47199 | 78 | 50557833 |
Pericarditis | 55.03 | 10.81 | 5 | 47208 | 78684 | 50479227 |
Ketosis | 54.76 | 10.81 | 20 | 47193 | 503 | 50557408 |
Completed suicide | 53.69 | 10.81 | 28 | 47185 | 131861 | 50426050 |
Hypoglycaemia neonatal | 50.50 | 10.81 | 22 | 47191 | 886 | 50557025 |
Therapeutic product effect decreased | 49.57 | 10.81 | 33 | 47180 | 136017 | 50421894 |
Toxicity to various agents | 49.54 | 10.81 | 76 | 47137 | 212423 | 50345488 |
Infective pulmonary exacerbation of cystic fibrosis | 49.28 | 10.81 | 48 | 47165 | 7861 | 50550050 |
Abdominal discomfort | 49.22 | 10.81 | 88 | 47125 | 231553 | 50326358 |
Hyperkalaemia | 49.04 | 10.81 | 126 | 47087 | 47963 | 50509948 |
Wound | 48.46 | 10.81 | 19 | 47194 | 105775 | 50452136 |
Restrictive pulmonary disease | 46.79 | 10.81 | 24 | 47189 | 1400 | 50556511 |
Drug hypersensitivity | 45.95 | 10.81 | 104 | 47109 | 250906 | 50307005 |
Lactic acidosis | 45.59 | 10.81 | 98 | 47115 | 33257 | 50524654 |
Discomfort | 44.12 | 10.81 | 23 | 47190 | 108357 | 50449554 |
Lipodystrophy acquired | 42.52 | 10.81 | 22 | 47191 | 1307 | 50556604 |
Chronic kidney disease | 42.42 | 10.81 | 106 | 47107 | 39665 | 50518246 |
Wrong product administered | 42.06 | 10.81 | 37 | 47176 | 5323 | 50552588 |
Premature baby | 41.60 | 10.81 | 67 | 47146 | 18270 | 50539641 |
Euglycaemic diabetic ketoacidosis | 40.86 | 10.81 | 28 | 47185 | 2791 | 50555120 |
Heart sounds | 40.79 | 10.81 | 17 | 47196 | 613 | 50557298 |
Diabetes mellitus | 40.57 | 10.81 | 119 | 47094 | 48914 | 50508997 |
Foetal exposure during pregnancy | 40.43 | 10.81 | 83 | 47130 | 27276 | 50530635 |
Musculoskeletal stiffness | 39.45 | 10.81 | 37 | 47176 | 128444 | 50429467 |
Renal failure | 39.25 | 10.81 | 200 | 47013 | 106433 | 50451478 |
Prolonged expiration | 38.58 | 10.81 | 17 | 47196 | 704 | 50557207 |
Ketonuria | 38.37 | 10.81 | 15 | 47198 | 457 | 50557454 |
Myocardial infarction | 37.82 | 10.81 | 174 | 47039 | 88853 | 50469058 |
Oesophageal spasm | 36.14 | 10.81 | 24 | 47189 | 2272 | 50555639 |
Polycystic ovaries | 34.42 | 10.81 | 24 | 47189 | 2460 | 50555451 |
Dehydration | 33.93 | 10.81 | 251 | 46962 | 152198 | 50405713 |
Sleep apnoea syndrome | 33.62 | 10.81 | 71 | 47142 | 23797 | 50534114 |
Polyuria | 33.19 | 10.81 | 37 | 47176 | 7084 | 50550827 |
Helicobacter infection | 32.59 | 10.81 | 4 | 47209 | 49698 | 50508213 |
Sinusitis | 32.56 | 10.81 | 69 | 47144 | 170489 | 50387422 |
Insulin resistance | 32.50 | 10.81 | 15 | 47198 | 693 | 50557218 |
Bladder agenesis | 32.45 | 10.81 | 10 | 47203 | 146 | 50557765 |
Genitalia external ambiguous | 32.01 | 10.81 | 10 | 47203 | 153 | 50557758 |
Cloacal exstrophy | 32.01 | 10.81 | 10 | 47203 | 153 | 50557758 |
Oesophageal pain | 31.83 | 10.81 | 24 | 47189 | 2778 | 50555133 |
Congenital ectopic bladder | 31.61 | 10.81 | 9 | 47204 | 98 | 50557813 |
Swelling | 31.50 | 10.81 | 90 | 47123 | 200782 | 50357129 |
Caudal regression syndrome | 31.37 | 10.81 | 10 | 47203 | 164 | 50557747 |
Lethargy | 30.92 | 10.81 | 109 | 47104 | 49323 | 50508588 |
Gastrointestinal malformation | 30.77 | 10.81 | 10 | 47203 | 175 | 50557736 |
Meconium stain | 30.25 | 10.81 | 10 | 47203 | 185 | 50557726 |
Anencephaly | 29.34 | 10.81 | 10 | 47203 | 204 | 50557707 |
Gastrointestinal disorder congenital | 29.23 | 10.81 | 9 | 47204 | 131 | 50557780 |
Congenital genital malformation | 28.56 | 10.81 | 9 | 47204 | 142 | 50557769 |
Tethered cord syndrome | 28.42 | 10.81 | 10 | 47203 | 225 | 50557686 |
Product physical issue | 28.33 | 10.81 | 27 | 47186 | 4305 | 50553606 |
Pre-eclampsia | 27.96 | 10.81 | 36 | 47177 | 8008 | 50549903 |
Hypersensitivity | 27.79 | 10.81 | 105 | 47108 | 215056 | 50342855 |
Coronavirus test positive | 27.73 | 10.81 | 13 | 47200 | 623 | 50557288 |
Blood ketone body | 27.59 | 10.81 | 7 | 47206 | 47 | 50557864 |
Pancreatitis | 27.54 | 10.81 | 95 | 47118 | 42519 | 50515392 |
Neural tube defect | 26.43 | 10.81 | 9 | 47204 | 183 | 50557728 |
Respiration abnormal | 26.38 | 10.81 | 28 | 47185 | 5074 | 50552837 |
Diabetic nephropathy | 26.05 | 10.81 | 16 | 47197 | 1323 | 50556588 |
Sepsis neonatal | 25.83 | 10.81 | 11 | 47202 | 419 | 50557492 |
Irritable bowel syndrome | 25.68 | 10.81 | 8 | 47205 | 51433 | 50506478 |
Diabetic gastroparesis | 25.56 | 10.81 | 9 | 47204 | 203 | 50557708 |
Type 1 diabetes mellitus | 25.46 | 10.81 | 22 | 47191 | 3091 | 50554820 |
Therapeutic product effect incomplete | 25.10 | 10.81 | 29 | 47184 | 91486 | 50466425 |
Fracture blisters | 24.36 | 10.81 | 7 | 47206 | 79 | 50557832 |
Dyslipidaemia | 24.35 | 10.81 | 29 | 47184 | 5959 | 50551952 |
Accidental underdose | 24.29 | 10.81 | 12 | 47201 | 646 | 50557265 |
Anal atresia | 23.48 | 10.81 | 10 | 47203 | 381 | 50557530 |
Vomiting | 23.24 | 10.81 | 578 | 46635 | 460180 | 50097731 |
International normalised ratio abnormal | 23.06 | 10.81 | 20 | 47193 | 2823 | 50555088 |
Cystic fibrosis | 22.93 | 10.81 | 20 | 47193 | 2844 | 50555067 |
Device failure | 22.86 | 10.81 | 27 | 47186 | 5501 | 50552410 |
Impaired gastric emptying | 22.77 | 10.81 | 34 | 47179 | 8684 | 50549227 |
Nasopharyngitis | 22.49 | 10.81 | 98 | 47115 | 192829 | 50365082 |
Bicuspid aortic valve | 22.36 | 10.81 | 7 | 47206 | 108 | 50557803 |
Cerebrovascular accident | 22.26 | 10.81 | 158 | 47055 | 94522 | 50463389 |
Hospitalisation | 21.31 | 10.81 | 122 | 47091 | 67815 | 50490096 |
Mobility decreased | 21.21 | 10.81 | 26 | 47187 | 79922 | 50477989 |
Diabetic hyperosmolar coma | 20.72 | 10.81 | 9 | 47204 | 360 | 50557551 |
Off label use | 20.65 | 10.81 | 315 | 46898 | 474111 | 50083800 |
Acute myocardial infarction | 20.45 | 10.81 | 67 | 47146 | 29206 | 50528705 |
Hyperhidrosis | 20.31 | 10.81 | 148 | 47065 | 89278 | 50468633 |
Caesarean section | 20.28 | 10.81 | 45 | 47168 | 15594 | 50542317 |
Neonatal respiratory distress syndrome | 20.19 | 10.81 | 18 | 47195 | 2636 | 50555275 |
Meningomyelocele | 19.86 | 10.81 | 10 | 47203 | 561 | 50557350 |
Large intestine polyp | 19.73 | 10.81 | 29 | 47184 | 7303 | 50550608 |
Flank pain | 19.62 | 10.81 | 40 | 47173 | 13075 | 50544836 |
Dialysis | 19.41 | 10.81 | 33 | 47180 | 9405 | 50548506 |
Umbilical cord abnormality | 19.34 | 10.81 | 10 | 47203 | 593 | 50557318 |
Rash | 19.19 | 10.81 | 290 | 46923 | 437181 | 50120730 |
Depressive symptom | 19.15 | 10.81 | 19 | 47194 | 3181 | 50554730 |
Gastrointestinal disorder | 19.04 | 10.81 | 37 | 47176 | 94419 | 50463492 |
Productive cough | 18.79 | 10.81 | 98 | 47115 | 52596 | 50505315 |
Hip arthroplasty | 18.65 | 10.81 | 3 | 47210 | 30426 | 50527485 |
Dyspnoea | 18.61 | 10.81 | 654 | 46559 | 546954 | 50010957 |
Premature delivery | 18.22 | 10.81 | 56 | 47157 | 23607 | 50534304 |
Spina bifida | 17.98 | 10.81 | 10 | 47203 | 687 | 50557224 |
Shoulder dystocia | 17.93 | 10.81 | 3 | 47210 | 0 | 50557911 |
Hyperglycaemic unconsciousness | 17.93 | 10.81 | 3 | 47210 | 0 | 50557911 |
Diabetic ketoacidotic hyperglycaemic coma | 17.77 | 10.81 | 5 | 47208 | 52 | 50557859 |
Fear-related avoidance of activities | 17.67 | 10.81 | 6 | 47207 | 121 | 50557790 |
Restless legs syndrome | 17.61 | 10.81 | 43 | 47170 | 15854 | 50542057 |
Abscess | 17.32 | 10.81 | 40 | 47173 | 14232 | 50543679 |
Fatigue | 17.26 | 10.81 | 516 | 46697 | 707085 | 49850826 |
Exomphalos | 17.25 | 10.81 | 9 | 47204 | 544 | 50557367 |
Congenital anomaly | 17.22 | 10.81 | 13 | 47200 | 1508 | 50556403 |
Knee arthroplasty | 17.14 | 10.81 | 6 | 47207 | 35840 | 50522071 |
Decreased insulin requirement | 17.14 | 10.81 | 6 | 47207 | 133 | 50557778 |
Device operational issue | 16.88 | 10.81 | 7 | 47206 | 249 | 50557662 |
Product use issue | 16.76 | 10.81 | 77 | 47136 | 149398 | 50408513 |
Hypervolaemia | 16.61 | 10.81 | 57 | 47156 | 25442 | 50532469 |
Abdominal pain | 16.58 | 10.81 | 311 | 46902 | 235917 | 50321994 |
Blood ketone body increased | 16.53 | 10.81 | 7 | 47206 | 263 | 50557648 |
Hepatic enzyme increased | 16.48 | 10.81 | 69 | 47144 | 137311 | 50420600 |
Hypoglycaemic encephalopathy | 16.33 | 10.81 | 7 | 47206 | 271 | 50557640 |
Maculopathy | 16.24 | 10.81 | 14 | 47199 | 1960 | 50555951 |
Impaired healing | 16.20 | 10.81 | 25 | 47188 | 69761 | 50488150 |
Appetite disorder | 16.19 | 10.81 | 24 | 47189 | 6090 | 50551821 |
Diabetic hepatopathy | 15.86 | 10.81 | 3 | 47210 | 3 | 50557908 |
Foetal hypokinesia | 15.78 | 10.81 | 8 | 47205 | 455 | 50557456 |
White blood cell count decreased | 15.68 | 10.81 | 56 | 47157 | 116666 | 50441245 |
Product container issue | 15.68 | 10.81 | 12 | 47201 | 1420 | 50556491 |
Rhabdomyolysis | 15.62 | 10.81 | 75 | 47138 | 38952 | 50518959 |
Product dispensing error | 15.60 | 10.81 | 29 | 47184 | 8862 | 50549049 |
Product administration error | 15.52 | 10.81 | 47 | 47166 | 19652 | 50538259 |
Acute painful neuropathy of rapid glycaemic control | 15.40 | 10.81 | 3 | 47210 | 4 | 50557907 |
Pemphigoid | 15.38 | 10.81 | 23 | 47190 | 5884 | 50552027 |
Device expulsion | 15.27 | 10.81 | 4 | 47209 | 28818 | 50529093 |
Hepatic encephalopathy | 15.15 | 10.81 | 30 | 47183 | 9606 | 50548305 |
Lymphoedema | 15.07 | 10.81 | 29 | 47184 | 9093 | 50548818 |
Headache | 15.04 | 10.81 | 359 | 46854 | 506176 | 50051735 |
Resting tremor | 14.96 | 10.81 | 9 | 47204 | 717 | 50557194 |
Sputum increased | 14.87 | 10.81 | 13 | 47200 | 1854 | 50556057 |
Extradural haematoma | 14.59 | 10.81 | 12 | 47201 | 1575 | 50556336 |
Systemic infection | 14.49 | 10.81 | 14 | 47199 | 2269 | 50555642 |
Loss of consciousness | 14.47 | 10.81 | 155 | 47058 | 104198 | 50453713 |
Immunosuppressant drug level increased | 14.34 | 10.81 | 16 | 47197 | 3066 | 50554845 |
Diabetic foot | 14.33 | 10.81 | 11 | 47202 | 1307 | 50556604 |
Blister | 14.32 | 10.81 | 37 | 47176 | 85381 | 50472530 |
Left ventricular hypertrophy | 14.27 | 10.81 | 20 | 47193 | 4825 | 50553086 |
Cholestasis | 14.18 | 10.81 | 54 | 47159 | 25347 | 50532564 |
Carcinoid crisis | 14.18 | 10.81 | 6 | 47207 | 225 | 50557686 |
Angina pectoris | 14.07 | 10.81 | 55 | 47158 | 26133 | 50531778 |
Intentional overdose | 13.93 | 10.81 | 103 | 47110 | 62401 | 50495510 |
High risk pregnancy | 13.79 | 10.81 | 5 | 47208 | 123 | 50557788 |
Urinary tract infection | 13.73 | 10.81 | 289 | 46924 | 223731 | 50334180 |
Hyperglycaemic hyperosmolar nonketotic syndrome | 13.59 | 10.81 | 8 | 47205 | 612 | 50557299 |
Fluid retention | 13.37 | 10.81 | 87 | 47126 | 50562 | 50507349 |
Mental status changes | 13.31 | 10.81 | 68 | 47145 | 36204 | 50521707 |
Rales | 13.27 | 10.81 | 29 | 47184 | 9949 | 50547962 |
Anti-insulin antibody increased | 13.13 | 10.81 | 4 | 47209 | 56 | 50557855 |
Splenic thrombosis | 13.12 | 10.81 | 3 | 47210 | 12 | 50557899 |
Infection | 13.08 | 10.81 | 101 | 47112 | 172853 | 50385058 |
Conjoined twins | 13.07 | 10.81 | 6 | 47207 | 274 | 50557637 |
Therapeutic response decreased | 12.91 | 10.81 | 15 | 47198 | 47216 | 50510695 |
Ataxia | 12.91 | 10.81 | 35 | 47178 | 13751 | 50544160 |
Oedema peripheral | 12.87 | 10.81 | 213 | 47000 | 157748 | 50400163 |
Renal hypertension | 12.86 | 10.81 | 5 | 47208 | 150 | 50557761 |
Macrosomia | 12.82 | 10.81 | 4 | 47209 | 61 | 50557850 |
Incorrect dose administered by device | 12.79 | 10.81 | 16 | 47197 | 3459 | 50554452 |
Multiple lentigines syndrome | 12.77 | 10.81 | 5 | 47208 | 153 | 50557758 |
Diabetic coma | 12.71 | 10.81 | 8 | 47205 | 691 | 50557220 |
Sopor | 12.57 | 10.81 | 44 | 47169 | 19835 | 50538076 |
Retinopathy | 12.48 | 10.81 | 14 | 47199 | 2698 | 50555213 |
Malaise | 12.44 | 10.81 | 405 | 46808 | 335127 | 50222784 |
Foetal macrosomia | 12.36 | 10.81 | 4 | 47209 | 69 | 50557842 |
Congenital aortic valve stenosis | 12.36 | 10.81 | 4 | 47209 | 69 | 50557842 |
Diabetic retinal oedema | 12.20 | 10.81 | 6 | 47207 | 320 | 50557591 |
Bursitis | 11.87 | 10.81 | 3 | 47210 | 22132 | 50535779 |
Pancreas transplant | 11.84 | 10.81 | 3 | 47210 | 20 | 50557891 |
Pancreatic carcinoma | 11.83 | 10.81 | 21 | 47192 | 6193 | 50551718 |
Cardiac septal hypertrophy | 11.80 | 10.81 | 5 | 47208 | 188 | 50557723 |
Jaundice neonatal | 11.62 | 10.81 | 8 | 47205 | 803 | 50557108 |
Blood ketone body present | 11.59 | 10.81 | 3 | 47210 | 22 | 50557889 |
Drug abuse | 11.58 | 10.81 | 24 | 47189 | 59822 | 50498089 |
Haemodialysis complication | 11.56 | 10.81 | 5 | 47208 | 198 | 50557713 |
Incorrect dose administered | 11.49 | 10.81 | 81 | 47132 | 48333 | 50509578 |
Polymorphic light eruption | 11.37 | 10.81 | 3 | 47210 | 24 | 50557887 |
Adrenal adenoma | 11.34 | 10.81 | 8 | 47205 | 835 | 50557076 |
Glucose-6-phosphate dehydrogenase deficiency | 11.30 | 10.81 | 5 | 47208 | 209 | 50557702 |
Hip fracture | 11.24 | 10.81 | 51 | 47162 | 25880 | 50532031 |
Hepatocellular injury | 11.22 | 10.81 | 51 | 47162 | 25896 | 50532015 |
Selective eating disorder | 11.19 | 10.81 | 11 | 47202 | 1821 | 50556090 |
Cellulitis | 11.17 | 10.81 | 108 | 47105 | 70690 | 50487221 |
Therapy non-responder | 11.16 | 10.81 | 19 | 47194 | 51003 | 50506908 |
Neutrophil count decreased | 11.15 | 10.81 | 16 | 47197 | 46010 | 50511901 |
Febrile neutropenia | 11.13 | 10.81 | 50 | 47163 | 97617 | 50460294 |
Dermo-hypodermitis | 10.96 | 10.81 | 5 | 47208 | 225 | 50557686 |
Intentional product use issue | 10.94 | 10.81 | 36 | 47177 | 76882 | 50481029 |
Anogenital warts | 10.93 | 10.81 | 6 | 47207 | 402 | 50557509 |
Eczema | 10.86 | 10.81 | 46 | 47167 | 22656 | 50535255 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hypoglycaemia | 1086.55 | 10.71 | 742 | 41985 | 47604 | 29484196 |
Blood glucose increased | 624.31 | 10.71 | 582 | 42145 | 58402 | 29473398 |
Diabetic ketoacidosis | 613.12 | 10.71 | 346 | 42381 | 15727 | 29516073 |
Blood glucose decreased | 342.99 | 10.71 | 215 | 42512 | 11854 | 29519946 |
Diabetes mellitus inadequate control | 257.07 | 10.71 | 180 | 42547 | 11954 | 29519846 |
Hyperglycaemia | 237.96 | 10.71 | 270 | 42457 | 34017 | 29497783 |
Hypoglycaemic unconsciousness | 205.24 | 10.71 | 66 | 42661 | 697 | 29531103 |
Hypoglycaemic coma | 179.37 | 10.71 | 79 | 42648 | 2084 | 29529716 |
Blood glucose fluctuation | 174.80 | 10.71 | 91 | 42636 | 3506 | 29528294 |
Appendicolith | 132.78 | 10.71 | 75 | 42652 | 3405 | 29528395 |
Ketoacidosis | 93.82 | 10.71 | 61 | 42666 | 3578 | 29528222 |
Drug abuse | 88.93 | 10.71 | 7 | 42720 | 79876 | 29451924 |
Toxicity to various agents | 84.49 | 10.71 | 76 | 42651 | 173585 | 29358215 |
Glycosylated haemoglobin increased | 84.34 | 10.71 | 85 | 42642 | 9341 | 29522459 |
Appendicitis | 76.42 | 10.71 | 78 | 42649 | 8701 | 29523099 |
Acute kidney injury | 70.16 | 10.71 | 636 | 42091 | 264631 | 29267169 |
Diabetic retinopathy | 67.88 | 10.71 | 37 | 42690 | 1565 | 29530235 |
Product quality issue | 67.23 | 10.71 | 98 | 42629 | 15797 | 29516003 |
Diabetic metabolic decompensation | 66.44 | 10.71 | 35 | 42692 | 1381 | 29530419 |
Blood glucose abnormal | 65.14 | 10.71 | 56 | 42671 | 5027 | 29526773 |
Hypoglycaemic seizure | 64.20 | 10.71 | 22 | 42705 | 287 | 29531513 |
Completed suicide | 62.59 | 10.71 | 26 | 42701 | 90220 | 29441580 |
Drug ineffective | 55.90 | 10.71 | 303 | 42424 | 362867 | 29168933 |
Product leakage | 53.89 | 10.71 | 21 | 42706 | 402 | 29531398 |
Anti-insulin antibody positive | 52.90 | 10.71 | 17 | 42710 | 179 | 29531621 |
Ascites | 50.21 | 10.71 | 141 | 42586 | 36478 | 29495322 |
Cardiogenic shock | 46.13 | 10.71 | 92 | 42635 | 19098 | 29512702 |
Hypoglycaemia neonatal | 44.69 | 10.71 | 29 | 42698 | 1695 | 29530105 |
Stress | 43.47 | 10.71 | 96 | 42631 | 21394 | 29510406 |
Abdominal distension | 42.99 | 10.71 | 155 | 42572 | 45756 | 29486044 |
Device malfunction | 39.73 | 10.71 | 55 | 42672 | 8452 | 29523348 |
Hyperkalaemia | 38.34 | 10.71 | 183 | 42544 | 61209 | 29470591 |
Wrong product administered | 35.39 | 10.71 | 38 | 42689 | 4493 | 29527307 |
Diabetic neuropathy | 32.03 | 10.71 | 33 | 42694 | 3720 | 29528080 |
Liquid product physical issue | 29.90 | 10.71 | 13 | 42714 | 332 | 29531468 |
Diabetic foot | 29.59 | 10.71 | 25 | 42702 | 2191 | 29529609 |
Periodontitis | 29.55 | 10.71 | 23 | 42704 | 1794 | 29530006 |
Pulmonary valve stenosis congenital | 29.28 | 10.71 | 10 | 42717 | 129 | 29531671 |
Vomiting | 28.71 | 10.71 | 448 | 42279 | 211812 | 29319988 |
Chronic kidney disease | 27.59 | 10.71 | 115 | 42612 | 36301 | 29495499 |
Insulin resistance | 27.35 | 10.71 | 14 | 42713 | 520 | 29531280 |
Hypoglycaemia unawareness | 27.33 | 10.71 | 9 | 42718 | 103 | 29531697 |
Diabetic nephropathy | 26.59 | 10.71 | 22 | 42705 | 1873 | 29529927 |
Cutaneous amyloidosis | 26.30 | 10.71 | 7 | 42720 | 35 | 29531765 |
Infective pulmonary exacerbation of cystic fibrosis | 25.71 | 10.71 | 38 | 42689 | 6198 | 29525602 |
Lymphangitis | 24.51 | 10.71 | 13 | 42714 | 520 | 29531280 |
Diabetic ketoacidotic hyperglycaemic coma | 24.41 | 10.71 | 9 | 42718 | 147 | 29531653 |
Gallbladder neoplasm | 23.43 | 10.71 | 6 | 42721 | 25 | 29531775 |
Insulin autoimmune syndrome | 23.08 | 10.71 | 10 | 42717 | 253 | 29531547 |
Febrile neutropenia | 22.98 | 10.71 | 84 | 42643 | 112156 | 29419644 |
Diabetic macroangiopathy | 22.94 | 10.71 | 5 | 42722 | 8 | 29531792 |
Pemphigoid | 22.78 | 10.71 | 40 | 42687 | 7541 | 29524259 |
Foetal exposure during pregnancy | 22.63 | 10.71 | 103 | 42624 | 33764 | 29498036 |
Cystic fibrosis | 22.36 | 10.71 | 18 | 42709 | 1474 | 29530326 |
Hypoglycaemic encephalopathy | 22.21 | 10.71 | 10 | 42717 | 278 | 29531522 |
Diabetic complication | 21.86 | 10.71 | 13 | 42714 | 650 | 29531150 |
Loss of consciousness | 21.75 | 10.71 | 182 | 42545 | 73874 | 29457926 |
Bronchopneumopathy | 21.68 | 10.71 | 11 | 42716 | 401 | 29531399 |
Vitreous haemorrhage | 21.48 | 10.71 | 20 | 42707 | 1993 | 29529807 |
Diabetes mellitus | 20.16 | 10.71 | 112 | 42615 | 39719 | 29492081 |
Congenital bladder anomaly | 19.54 | 10.71 | 9 | 42718 | 264 | 29531536 |
Congenital cystic kidney disease | 19.16 | 10.71 | 10 | 42717 | 387 | 29531413 |
Product use in unapproved indication | 19.13 | 10.71 | 63 | 42664 | 86812 | 29444988 |
Anti-insulin antibody | 19.13 | 10.71 | 5 | 42722 | 23 | 29531777 |
Sepsis | 18.81 | 10.71 | 300 | 42427 | 142382 | 29389418 |
Genitalia external ambiguous | 18.37 | 10.71 | 8 | 42719 | 205 | 29531595 |
Wrong technique in device usage process | 18.22 | 10.71 | 14 | 42713 | 1071 | 29530729 |
Therapeutic product effect incomplete | 18.12 | 10.71 | 18 | 42709 | 39287 | 29492513 |
Treatment failure | 18.11 | 10.71 | 16 | 42711 | 36923 | 29494877 |
Diabetic coma | 17.51 | 10.71 | 12 | 42715 | 768 | 29531032 |
Death | 17.30 | 10.71 | 370 | 42357 | 341714 | 29190086 |
Infusion related reaction | 17.10 | 10.71 | 23 | 42704 | 43863 | 29487937 |
General physical health deterioration | 17.01 | 10.71 | 225 | 42502 | 102632 | 29429168 |
Hallucination | 16.85 | 10.71 | 24 | 42703 | 44688 | 29487112 |
Pancreatitis | 16.77 | 10.71 | 96 | 42631 | 34418 | 29497382 |
Renal aplasia | 16.76 | 10.71 | 11 | 42716 | 655 | 29531145 |
Gingival hypertrophy | 16.73 | 10.71 | 16 | 42711 | 1649 | 29530151 |
Aggression | 16.71 | 10.71 | 16 | 42711 | 35525 | 29496275 |
Toe amputation | 16.70 | 10.71 | 18 | 42709 | 2137 | 29529663 |
Adenocarcinoma pancreas | 16.67 | 10.71 | 14 | 42713 | 1217 | 29530583 |
Diabetic ketosis | 16.56 | 10.71 | 6 | 42721 | 93 | 29531707 |
Osteitis | 16.46 | 10.71 | 15 | 42712 | 1454 | 29530346 |
Hepatic cirrhosis | 16.36 | 10.71 | 52 | 42675 | 14392 | 29517408 |
Disease progression | 16.30 | 10.71 | 62 | 42665 | 81854 | 29449946 |
Incorrect dose administered | 16.20 | 10.71 | 92 | 42635 | 32892 | 29498908 |
Impaired gastric emptying | 16.09 | 10.71 | 21 | 42706 | 3049 | 29528751 |
Fine motor skill dysfunction | 15.76 | 10.71 | 15 | 42712 | 1536 | 29530264 |
Product administration error | 15.74 | 10.71 | 51 | 42676 | 14259 | 29517541 |
Product physical issue | 15.41 | 10.71 | 17 | 42710 | 2071 | 29529729 |
Diabetic foot infection | 15.07 | 10.71 | 10 | 42717 | 607 | 29531193 |
Hyperinsulinaemic hypoglycaemia | 14.97 | 10.71 | 5 | 42722 | 60 | 29531740 |
Cardiac output decreased | 14.60 | 10.71 | 11 | 42716 | 817 | 29530983 |
Polycythaemia neonatorum | 14.55 | 10.71 | 3 | 42724 | 3 | 29531797 |
Ventricular fibrillation | 14.42 | 10.71 | 53 | 42674 | 15780 | 29516020 |
Hepatotoxicity | 14.36 | 10.71 | 4 | 42723 | 17863 | 29513937 |
Condition aggravated | 14.17 | 10.71 | 139 | 42588 | 146156 | 29385644 |
Cold sweat | 14.08 | 10.71 | 36 | 42691 | 8806 | 29522994 |
Foetal hypokinesia | 14.02 | 10.71 | 8 | 42719 | 370 | 29531430 |
Blood ketone body increased | 13.94 | 10.71 | 8 | 42719 | 374 | 29531426 |
Truncus arteriosus persistent | 13.89 | 10.71 | 4 | 42723 | 28 | 29531772 |
Skin ulcer | 13.88 | 10.71 | 59 | 42668 | 18781 | 29513019 |
Hyponatraemia | 13.81 | 10.71 | 154 | 42573 | 67479 | 29464321 |
Dry gangrene | 13.77 | 10.71 | 8 | 42719 | 383 | 29531417 |
Herpes zoster reactivation | 13.60 | 10.71 | 7 | 42720 | 263 | 29531537 |
Treatment noncompliance | 13.53 | 10.71 | 70 | 42657 | 24157 | 29507643 |
Neonatal respiratory depression | 13.38 | 10.71 | 8 | 42719 | 404 | 29531396 |
Ketosis | 13.19 | 10.71 | 8 | 42719 | 415 | 29531385 |
Product complaint | 13.09 | 10.71 | 26 | 42701 | 5379 | 29526421 |
Overdose | 13.08 | 10.71 | 65 | 42662 | 79754 | 29452046 |
Nausea | 13.05 | 10.71 | 526 | 42201 | 288729 | 29243071 |
Trisomy 18 | 12.60 | 10.71 | 6 | 42721 | 190 | 29531610 |
Spermatic cord disorder | 12.48 | 10.71 | 3 | 42724 | 9 | 29531791 |
Pneumobilia | 12.37 | 10.71 | 4 | 42723 | 43 | 29531757 |
Heart disease congenital | 12.29 | 10.71 | 12 | 42715 | 1268 | 29530532 |
Drug resistance | 12.26 | 10.71 | 8 | 42719 | 21532 | 29510268 |
Postprandial hypoglycaemia | 12.24 | 10.71 | 3 | 42724 | 10 | 29531790 |
Anxiety | 12.08 | 10.71 | 73 | 42654 | 85292 | 29446508 |
Hyperhidrosis | 11.86 | 10.71 | 144 | 42583 | 64396 | 29467404 |
Basophil count abnormal | 11.81 | 10.71 | 3 | 42724 | 12 | 29531788 |
Hunger | 11.76 | 10.71 | 12 | 42715 | 1337 | 29530463 |
Abdominal pain | 11.76 | 10.71 | 267 | 42460 | 135090 | 29396710 |
Product label issue | 11.72 | 10.71 | 6 | 42721 | 223 | 29531577 |
Hepatocellular carcinoma | 11.57 | 10.71 | 29 | 42698 | 7009 | 29524791 |
Insulin-requiring type 2 diabetes mellitus | 11.56 | 10.71 | 5 | 42722 | 126 | 29531674 |
Cellulitis | 11.56 | 10.71 | 109 | 42618 | 45731 | 29486069 |
Neutrophil count decreased | 11.48 | 10.71 | 29 | 42698 | 43538 | 29488262 |
Hydrops foetalis | 11.45 | 10.71 | 6 | 42721 | 234 | 29531566 |
Funguria | 11.41 | 10.71 | 4 | 42723 | 56 | 29531744 |
Pancreatic carcinoma | 11.27 | 10.71 | 29 | 42698 | 7121 | 29524679 |
Gangrene | 11.08 | 10.71 | 21 | 42706 | 4197 | 29527603 |
Mucosal inflammation | 10.91 | 10.71 | 18 | 42709 | 31577 | 29500223 |
Device failure | 10.89 | 10.71 | 14 | 42713 | 2002 | 29529798 |
Peritonitis bacterial | 10.84 | 10.71 | 25 | 42702 | 5731 | 29526069 |
Euglycaemic diabetic ketoacidosis | 10.80 | 10.71 | 16 | 42711 | 2614 | 29529186 |
Haemolytic anaemia | 10.75 | 10.71 | 34 | 42693 | 9385 | 29522415 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hypoglycaemia | 2061.27 | 9.91 | 1291 | 74144 | 88601 | 64334696 |
Diabetic ketoacidosis | 1678.67 | 9.91 | 779 | 74656 | 29066 | 64394231 |
Blood glucose increased | 1395.45 | 9.91 | 1050 | 74385 | 97023 | 64326274 |
Blood glucose decreased | 623.14 | 9.91 | 369 | 75066 | 22754 | 64400543 |
Hyperglycaemia | 552.21 | 9.91 | 503 | 74932 | 60465 | 64362832 |
Diabetes mellitus inadequate control | 499.28 | 9.91 | 311 | 75124 | 21010 | 64402287 |
Hypoglycaemic unconsciousness | 321.85 | 9.91 | 97 | 75338 | 1024 | 64422273 |
Hypoglycaemic coma | 321.70 | 9.91 | 137 | 75298 | 4137 | 64419160 |
Blood glucose fluctuation | 263.41 | 9.91 | 132 | 75303 | 5823 | 64417474 |
Ketoacidosis | 262.68 | 9.91 | 138 | 75297 | 6725 | 64416572 |
Acute kidney injury | 219.13 | 9.91 | 1071 | 74364 | 448169 | 63975128 |
Diabetic retinopathy | 213.65 | 9.91 | 91 | 75344 | 2748 | 64420549 |
Glycosylated haemoglobin increased | 212.84 | 9.91 | 165 | 75270 | 15854 | 64407443 |
Product leakage | 184.88 | 9.91 | 56 | 75379 | 602 | 64422695 |
Diabetic metabolic decompensation | 177.76 | 9.91 | 79 | 75356 | 2649 | 64420648 |
Product quality issue | 158.81 | 9.91 | 185 | 75250 | 29614 | 64393683 |
Appendicolith | 147.87 | 9.91 | 75 | 75360 | 3394 | 64419903 |
Drug ineffective | 143.71 | 9.91 | 504 | 74931 | 839743 | 63583554 |
Completed suicide | 129.86 | 9.91 | 50 | 75385 | 224364 | 64198933 |
Toxicity to various agents | 129.07 | 9.91 | 141 | 75294 | 363372 | 64059925 |
Blood glucose abnormal | 123.19 | 9.91 | 94 | 75341 | 8819 | 64414478 |
Hypoglycaemic seizure | 112.76 | 9.91 | 40 | 75395 | 728 | 64422569 |
Anti-insulin antibody positive | 96.21 | 9.91 | 28 | 75407 | 259 | 64423038 |
Hypoglycaemia unawareness | 90.15 | 9.91 | 24 | 75411 | 154 | 64423143 |
Drug intolerance | 84.75 | 9.91 | 58 | 75377 | 187934 | 64235363 |
Synovitis | 83.97 | 9.91 | 9 | 75426 | 99081 | 64324216 |
Diabetic neuropathy | 83.92 | 9.91 | 62 | 75373 | 5539 | 64417758 |
Infusion related reaction | 82.13 | 9.91 | 45 | 75390 | 164422 | 64258875 |
Liquid product physical issue | 80.39 | 9.91 | 32 | 75403 | 810 | 64422487 |
Arthropathy | 78.63 | 9.91 | 22 | 75413 | 120945 | 64302352 |
Drug abuse | 77.35 | 9.91 | 29 | 75406 | 132345 | 64290952 |
Hyperkalaemia | 77.17 | 9.91 | 277 | 75158 | 100852 | 64322445 |
Infective pulmonary exacerbation of cystic fibrosis | 72.68 | 9.91 | 79 | 75356 | 11717 | 64411580 |
Appendicitis | 71.88 | 9.91 | 84 | 75351 | 13485 | 64409812 |
Joint swelling | 71.53 | 9.91 | 88 | 75347 | 215294 | 64208003 |
Diabetic ketosis | 65.28 | 9.91 | 22 | 75413 | 341 | 64422956 |
Treatment failure | 62.75 | 9.91 | 29 | 75406 | 116787 | 64306510 |
Wrong product administered | 62.68 | 9.91 | 60 | 75375 | 7660 | 64415637 |
Hyper IgE syndrome | 62.27 | 9.91 | 23 | 75412 | 472 | 64422825 |
Hand deformity | 60.86 | 9.91 | 3 | 75432 | 62768 | 64360529 |
Arthralgia | 59.79 | 9.91 | 290 | 75145 | 441970 | 63981327 |
Pain | 59.66 | 9.91 | 391 | 75044 | 553120 | 63870177 |
Exposure during pregnancy | 57.75 | 9.91 | 211 | 75224 | 77464 | 64345833 |
Ketosis | 57.01 | 9.91 | 26 | 75409 | 927 | 64422370 |
Rheumatoid arthritis | 56.81 | 9.91 | 65 | 75370 | 164229 | 64259068 |
Systemic lupus erythematosus | 56.60 | 9.91 | 11 | 75424 | 77601 | 64345696 |
Alopecia | 55.73 | 9.91 | 67 | 75368 | 165623 | 64257674 |
Chronic kidney disease | 55.16 | 9.91 | 171 | 75264 | 57748 | 64365549 |
Contraindicated product administered | 53.09 | 9.91 | 30 | 75405 | 107799 | 64315498 |
Diabetic nephropathy | 50.50 | 9.91 | 34 | 75401 | 2620 | 64420677 |
Insulin resistance | 50.46 | 9.91 | 25 | 75410 | 1075 | 64422222 |
Glossodynia | 47.53 | 9.91 | 9 | 75426 | 64687 | 64358610 |
Vomiting | 46.46 | 9.91 | 903 | 74532 | 550214 | 63873083 |
Euglycaemic diabetic ketoacidosis | 45.74 | 9.91 | 43 | 75392 | 5367 | 64417930 |
Drug hypersensitivity | 44.26 | 9.91 | 137 | 75298 | 237678 | 64185619 |
Sinusitis | 43.97 | 9.91 | 64 | 75371 | 145864 | 64277433 |
Therapeutic product effect decreased | 43.96 | 9.91 | 42 | 75393 | 115309 | 64307988 |
Product physical issue | 42.52 | 9.91 | 34 | 75401 | 3415 | 64419882 |
Diabetic ketoacidotic hyperglycaemic coma | 41.90 | 9.91 | 14 | 75421 | 211 | 64423086 |
Abdominal distension | 40.35 | 9.91 | 220 | 75215 | 95774 | 64327523 |
Pemphigoid | 39.02 | 9.91 | 61 | 75374 | 12925 | 64410372 |
Device malfunction | 38.66 | 9.91 | 72 | 75363 | 17561 | 64405736 |
Cystic fibrosis | 38.43 | 9.91 | 32 | 75403 | 3402 | 64419895 |
Oesophageal spasm | 37.94 | 9.91 | 28 | 75407 | 2497 | 64420800 |
Therapeutic product effect incomplete | 37.91 | 9.91 | 39 | 75396 | 103443 | 64319854 |
Diabetic foot | 37.85 | 9.91 | 30 | 75405 | 2975 | 64420322 |
Pancreatitis | 37.81 | 9.91 | 154 | 75281 | 59453 | 64363844 |
Diabetes mellitus | 37.72 | 9.91 | 166 | 75269 | 66308 | 64356989 |
Cardiogenic shock | 35.88 | 9.91 | 101 | 75334 | 32326 | 64390971 |
Heart sounds | 34.66 | 9.91 | 16 | 75419 | 587 | 64422710 |
Lactic acidosis | 34.57 | 9.91 | 153 | 75282 | 61257 | 64362040 |
Ascites | 34.55 | 9.91 | 154 | 75281 | 61847 | 64361450 |
Hypoglycaemic encephalopathy | 34.43 | 9.91 | 16 | 75419 | 596 | 64422701 |
Abdominal discomfort | 33.93 | 9.91 | 105 | 75330 | 182217 | 64241080 |
Hyperhidrosis | 33.77 | 9.91 | 256 | 75179 | 124664 | 64298633 |
Product administration error | 33.48 | 9.91 | 89 | 75346 | 27554 | 64395743 |
Ketonuria | 33.18 | 9.91 | 19 | 75416 | 1098 | 64422199 |
Nasopharyngitis | 33.00 | 9.91 | 118 | 75317 | 195955 | 64227342 |
Pericarditis | 32.83 | 9.91 | 16 | 75419 | 62500 | 64360797 |
Abdominal pain | 32.71 | 9.91 | 530 | 74905 | 311845 | 64111452 |
Polycystic ovaries | 32.61 | 9.91 | 24 | 75411 | 2131 | 64421166 |
Restrictive pulmonary disease | 32.44 | 9.91 | 24 | 75411 | 2148 | 64421149 |
Insulin autoimmune syndrome | 32.05 | 9.91 | 13 | 75422 | 346 | 64422951 |
Loss of consciousness | 32.04 | 9.91 | 289 | 75146 | 148076 | 64275221 |
Cutaneous amyloidosis | 31.57 | 9.91 | 8 | 75427 | 41 | 64423256 |
Helicobacter infection | 31.21 | 9.91 | 4 | 75431 | 38358 | 64384939 |
Blood ketone body increased | 30.90 | 9.91 | 15 | 75420 | 617 | 64422680 |
Dehydration | 30.33 | 9.91 | 387 | 75048 | 216376 | 64206921 |
Prolonged expiration | 29.94 | 9.91 | 16 | 75419 | 807 | 64422490 |
Oesophageal pain | 29.65 | 9.91 | 27 | 75408 | 3236 | 64420061 |
Vitreous haemorrhage | 28.96 | 9.91 | 26 | 75409 | 3059 | 64420238 |
Dyslipidaemia | 28.58 | 9.91 | 44 | 75391 | 9198 | 64414099 |
Musculoskeletal stiffness | 28.20 | 9.91 | 64 | 75371 | 123142 | 64300155 |
Irritable bowel syndrome | 27.88 | 9.91 | 5 | 75430 | 37364 | 64385933 |
Febrile neutropenia | 27.09 | 9.91 | 120 | 75315 | 187537 | 64235760 |
Headache | 27.08 | 9.91 | 446 | 74989 | 529021 | 63894276 |
Stress | 26.28 | 9.91 | 140 | 75295 | 60394 | 64362903 |
Incorrect dose administered | 26.02 | 9.91 | 140 | 75295 | 60625 | 64362672 |
Lethargy | 25.70 | 9.91 | 159 | 75276 | 72435 | 64350862 |
Pre-eclampsia | 25.66 | 9.91 | 34 | 75401 | 6197 | 64417100 |
Impaired gastric emptying | 24.59 | 9.91 | 40 | 75395 | 8764 | 64414533 |
Product use in unapproved indication | 24.27 | 9.91 | 115 | 75320 | 176503 | 64246794 |
Off label use | 24.16 | 9.91 | 560 | 74875 | 632246 | 63791051 |
Blood ketone body | 23.33 | 9.91 | 8 | 75427 | 131 | 64423166 |
Cold sweat | 23.07 | 9.91 | 56 | 75379 | 16399 | 64406898 |
Fracture blisters | 22.80 | 9.91 | 7 | 75428 | 79 | 64423218 |
Device operational issue | 22.31 | 9.91 | 10 | 75425 | 342 | 64422955 |
Neutrophil count decreased | 22.14 | 9.91 | 35 | 75400 | 77161 | 64346136 |
Discomfort | 21.96 | 9.91 | 38 | 75397 | 80840 | 64342457 |
Hepatocellular carcinoma | 21.88 | 9.91 | 37 | 75398 | 8366 | 64414931 |
Mobility decreased | 21.82 | 9.91 | 42 | 75393 | 85798 | 64337499 |
Type 1 diabetes mellitus | 21.77 | 9.91 | 30 | 75405 | 5675 | 64417622 |
Sepsis | 21.60 | 9.91 | 384 | 75051 | 229957 | 64193340 |
Renal failure | 21.57 | 9.91 | 315 | 75120 | 181373 | 64241924 |
Intentional product use issue | 21.44 | 9.91 | 50 | 75385 | 95314 | 64327983 |
Treatment noncompliance | 21.28 | 9.91 | 104 | 75331 | 43378 | 64379919 |
Muscle injury | 20.93 | 9.91 | 3 | 75432 | 26434 | 64396863 |
Diabetic hepatopathy | 20.77 | 9.91 | 4 | 75431 | 3 | 64423294 |
Lymphangitis | 20.74 | 9.91 | 15 | 75420 | 1296 | 64422001 |
Folliculitis | 20.43 | 9.91 | 5 | 75430 | 30072 | 64393225 |
Dyspnoea | 20.36 | 9.91 | 1031 | 74404 | 717643 | 63705654 |
Device failure | 20.34 | 9.91 | 29 | 75406 | 5663 | 64417634 |
Foetal macrosomia | 20.24 | 9.91 | 4 | 75431 | 4 | 64423293 |
Gastrointestinal disorder | 20.20 | 9.91 | 47 | 75388 | 89662 | 64333635 |
Bronchopneumopathy | 20.10 | 9.91 | 11 | 75424 | 582 | 64422715 |
Coronavirus test positive | 20.08 | 9.91 | 13 | 75422 | 938 | 64422359 |
Drug resistance | 19.98 | 9.91 | 8 | 75427 | 35094 | 64388203 |
Hospitalisation | 19.68 | 9.91 | 153 | 75282 | 75054 | 64348243 |
Respiration abnormal | 19.44 | 9.91 | 30 | 75405 | 6285 | 64417012 |
C-reactive protein abnormal | 19.40 | 9.91 | 5 | 75430 | 29042 | 64394255 |
Gallbladder neoplasm | 19.29 | 9.91 | 6 | 75429 | 71 | 64423226 |
Decreased insulin requirement | 18.94 | 9.91 | 7 | 75428 | 144 | 64423153 |
Polyuria | 18.77 | 9.91 | 44 | 75391 | 12599 | 64410698 |
Blood pressure fluctuation | 18.48 | 9.91 | 20 | 75415 | 51851 | 64371446 |
Cellulitis | 18.48 | 9.91 | 179 | 75256 | 93478 | 64329819 |
Hepatotoxicity | 18.43 | 9.91 | 12 | 75423 | 39950 | 64383347 |
Sleep apnoea syndrome | 18.07 | 9.91 | 76 | 75359 | 29756 | 64393541 |
Hepatic encephalopathy | 18.05 | 9.91 | 60 | 75375 | 21006 | 64402291 |
Adenocarcinoma pancreas | 18.01 | 9.91 | 16 | 75419 | 1857 | 64421440 |
Myocardial infarction | 17.94 | 9.91 | 283 | 75152 | 165538 | 64257759 |
Fear-related avoidance of activities | 17.92 | 9.91 | 6 | 75429 | 91 | 64423206 |
Product container issue | 17.89 | 9.91 | 12 | 75423 | 919 | 64422378 |
Swelling | 17.78 | 9.91 | 112 | 75323 | 160106 | 64263191 |
Periodontitis | 17.60 | 9.91 | 23 | 75412 | 4136 | 64419161 |
Hyperglycaemic unconsciousness | 17.26 | 9.91 | 3 | 75432 | 0 | 64423297 |
Wrong technique in device usage process | 17.23 | 9.91 | 19 | 75416 | 2863 | 64420434 |
Fluid retention | 17.14 | 9.91 | 124 | 75311 | 59482 | 64363815 |
Hypervolaemia | 16.93 | 9.91 | 89 | 75346 | 38196 | 64385101 |
Sputum increased | 16.80 | 9.91 | 21 | 75414 | 3614 | 64419683 |
C-reactive protein increased | 16.71 | 9.91 | 56 | 75379 | 94853 | 64328444 |
Foetal hypokinesia | 16.66 | 9.91 | 8 | 75427 | 321 | 64422976 |
Anti-insulin antibody increased | 16.62 | 9.91 | 6 | 75429 | 115 | 64423182 |
Lower respiratory tract infection | 16.54 | 9.91 | 56 | 75379 | 94558 | 64328739 |
Hypothermia | 16.52 | 9.91 | 56 | 75379 | 19800 | 64403497 |
Wound | 16.48 | 9.91 | 41 | 75394 | 76436 | 64346861 |
Haemorrhagic stroke | 16.29 | 9.91 | 36 | 75399 | 9915 | 64413382 |
Blood insulin increased | 16.17 | 9.91 | 8 | 75427 | 343 | 64422954 |
Gangrene | 16.13 | 9.91 | 30 | 75405 | 7308 | 64415989 |
Hyperinsulinaemic hypoglycaemia | 15.94 | 9.91 | 6 | 75429 | 130 | 64423167 |
Pancreatitis acute | 15.88 | 9.91 | 95 | 75340 | 42760 | 64380537 |
Blood ketone body present | 15.86 | 9.91 | 5 | 75430 | 62 | 64423235 |
Diabetic hyperosmolar coma | 15.64 | 9.91 | 10 | 75425 | 706 | 64422591 |
Hip arthroplasty | 15.62 | 9.91 | 3 | 75432 | 21348 | 64401949 |
Diabetic macroangiopathy | 15.49 | 9.91 | 6 | 75429 | 141 | 64423156 |
Systemic infection | 15.42 | 9.91 | 22 | 75413 | 4299 | 64418998 |
Diabetic gastroparesis | 15.36 | 9.91 | 7 | 75428 | 249 | 64423048 |
Insulin-requiring type 2 diabetes mellitus | 15.33 | 9.91 | 6 | 75429 | 145 | 64423152 |
Anti-insulin antibody | 15.30 | 9.91 | 5 | 75430 | 70 | 64423227 |
Hyperglycaemic hyperosmolar nonketotic syndrome | 15.18 | 9.91 | 14 | 75421 | 1705 | 64421592 |
Hyperglycaemic seizure | 15.18 | 9.91 | 3 | 75432 | 3 | 64423294 |
Arthritis | 15.06 | 9.91 | 49 | 75386 | 83765 | 64339532 |
Product dispensing error | 15.03 | 9.91 | 38 | 75397 | 11412 | 64411885 |
Increased insulin requirement | 14.92 | 9.91 | 6 | 75429 | 156 | 64423141 |
Acute painful neuropathy of rapid glycaemic control | 14.72 | 9.91 | 3 | 75432 | 4 | 64423293 |
Hypersensitivity | 14.59 | 9.91 | 153 | 75282 | 196299 | 64226998 |
Gingival hypertrophy | 14.54 | 9.91 | 17 | 75418 | 2730 | 64420567 |
Oedema peripheral | 14.51 | 9.91 | 335 | 75100 | 209982 | 64213315 |
Injection site reaction | 14.51 | 9.91 | 20 | 75415 | 46644 | 64376653 |
Dry gangrene | 14.32 | 9.91 | 10 | 75425 | 818 | 64422479 |
Respiratory arrest | 14.28 | 9.91 | 25 | 75410 | 52960 | 64370337 |
Product prescribing error | 14.25 | 9.91 | 80 | 75355 | 35189 | 64388108 |
Disease progression | 14.24 | 9.91 | 102 | 75333 | 141578 | 64281719 |
Premature delivery | 14.23 | 9.91 | 51 | 75384 | 18538 | 64404759 |
Cerebrovascular accident | 14.20 | 9.91 | 233 | 75202 | 137350 | 64285947 |
Poisoning | 14.17 | 9.91 | 4 | 75431 | 21875 | 64401422 |
Blood cholesterol increased | 14.07 | 9.91 | 23 | 75412 | 50043 | 64373254 |
Fine motor skill dysfunction | 14.01 | 9.91 | 22 | 75413 | 4677 | 64418620 |
Loss of personal independence in daily activities | 13.99 | 9.91 | 41 | 75394 | 72413 | 64350884 |
Product complaint | 13.98 | 9.91 | 38 | 75397 | 11916 | 64411381 |
Heart rate decreased | 13.94 | 9.91 | 27 | 75408 | 55040 | 64368257 |
White blood cell count decreased | 13.82 | 9.91 | 118 | 75317 | 157719 | 64265578 |
Glucose-6-phosphate dehydrogenase deficiency | 13.65 | 9.91 | 7 | 75428 | 324 | 64422973 |
Diabetic coma | 13.62 | 9.91 | 11 | 75424 | 1120 | 64422177 |
Red blood cell sedimentation rate increased | 13.58 | 9.91 | 10 | 75425 | 31225 | 64392072 |
Dialysis | 13.45 | 9.91 | 47 | 75388 | 16873 | 64406424 |
Product odour abnormal | 13.44 | 9.91 | 11 | 75424 | 1142 | 64422155 |
Device expulsion | 13.44 | 9.91 | 4 | 75431 | 21132 | 64402165 |
Diabetic retinal oedema | 13.34 | 9.91 | 7 | 75428 | 340 | 64422957 |
Malaise | 13.21 | 9.91 | 578 | 74857 | 395669 | 64027628 |
Nonreassuring foetal heart rate pattern | 13.11 | 9.91 | 3 | 75432 | 9 | 64423288 |
Angina pectoris | 13.09 | 9.91 | 94 | 75341 | 44987 | 64378310 |
Retrograde ejaculation | 13.05 | 9.91 | 6 | 75429 | 218 | 64423079 |
International normalised ratio abnormal | 13.04 | 9.91 | 22 | 75413 | 4966 | 64418331 |
End stage renal disease | 12.96 | 9.91 | 34 | 75401 | 10441 | 64412856 |
Therapy non-responder | 12.93 | 9.91 | 37 | 75398 | 65862 | 64357435 |
Peritonitis bacterial | 12.92 | 9.91 | 31 | 75404 | 9012 | 64414285 |
Cardiac failure | 12.86 | 9.91 | 222 | 75213 | 132151 | 64291146 |
Adverse drug reaction | 12.67 | 9.91 | 21 | 75414 | 45443 | 64377854 |
Sedation | 12.66 | 9.91 | 18 | 75417 | 41444 | 64381853 |
Myelosuppression | 12.66 | 9.91 | 6 | 75429 | 23824 | 64399473 |
Erythema | 12.58 | 9.91 | 149 | 75286 | 186921 | 64236376 |
Infection | 12.53 | 9.91 | 147 | 75288 | 184733 | 64238564 |
Hepatocellular injury | 12.38 | 9.91 | 93 | 75342 | 45142 | 64378155 |
Hepatic enzyme increased | 12.36 | 9.91 | 95 | 75340 | 129848 | 64293449 |
Intentional overdose | 12.31 | 9.91 | 160 | 75275 | 89784 | 64333513 |
Large intestine polyp | 12.23 | 9.91 | 34 | 75401 | 10803 | 64412494 |
Dialysis device insertion | 12.05 | 9.91 | 4 | 75431 | 59 | 64423238 |
Swollen tongue | 12.02 | 9.91 | 76 | 75359 | 34878 | 64388419 |
Fall | 11.96 | 9.91 | 599 | 74836 | 416227 | 64007070 |
Acetonaemia | 11.92 | 9.91 | 6 | 75429 | 267 | 64423030 |
Heart rate irregular | 11.63 | 9.91 | 9 | 75426 | 27404 | 64395893 |
Mental status changes | 11.62 | 9.91 | 116 | 75319 | 61046 | 64362251 |
Bone pain | 11.47 | 9.91 | 24 | 75411 | 47548 | 64375749 |
Accidental underdose | 11.46 | 9.91 | 8 | 75427 | 654 | 64422643 |
Hot flush | 11.42 | 9.91 | 23 | 75412 | 46212 | 64377085 |
Appetite disorder | 11.29 | 9.91 | 24 | 75411 | 6437 | 64416860 |
Acute myocardial infarction | 11.28 | 9.91 | 128 | 75307 | 69590 | 64353707 |
Flank pain | 11.21 | 9.91 | 43 | 75392 | 16146 | 64407151 |
Oral herpes | 11.13 | 9.91 | 6 | 75429 | 22146 | 64401151 |
Lymphoedema | 11.10 | 9.91 | 31 | 75404 | 9874 | 64413423 |
Foot amputation | 11.05 | 9.91 | 8 | 75427 | 693 | 64422604 |
Cystic fibrosis related diabetes | 11.02 | 9.91 | 5 | 75430 | 176 | 64423121 |
Conjunctivitis | 11.01 | 9.91 | 5 | 75430 | 20349 | 64402948 |
Hypokalaemia | 10.98 | 9.91 | 202 | 75233 | 121701 | 64301596 |
Condition aggravated | 10.92 | 9.91 | 342 | 75093 | 372084 | 64051213 |
Ventricular fibrillation | 10.92 | 9.91 | 56 | 75379 | 23804 | 64399493 |
Renal impairment | 10.89 | 9.91 | 220 | 75215 | 134797 | 64288500 |
Neutropenia | 10.88 | 9.91 | 206 | 75229 | 239418 | 64183879 |
Postprandial hypoglycaemia | 10.88 | 9.91 | 4 | 75431 | 81 | 64423216 |
Maculopathy | 10.87 | 9.91 | 14 | 75421 | 2482 | 64420815 |
Hepatic cirrhosis | 10.86 | 9.91 | 60 | 75375 | 26238 | 64397059 |
Diabetic foot infection | 10.83 | 9.91 | 8 | 75427 | 714 | 64422583 |
Subdural haemorrhage | 10.82 | 9.91 | 21 | 75414 | 5282 | 64418015 |
Rash | 10.73 | 9.91 | 433 | 75002 | 458116 | 63965181 |
High risk pregnancy | 10.70 | 9.91 | 4 | 75431 | 85 | 64423212 |
Drug delivery system issue | 10.69 | 9.91 | 3 | 75432 | 24 | 64423273 |
Depressive symptom | 10.67 | 9.91 | 19 | 75416 | 4477 | 64418820 |
Progressive multifocal leukoencephalopathy | 10.63 | 9.91 | 4 | 75431 | 18228 | 64405069 |
Incorrect dose administered by device | 10.62 | 9.91 | 18 | 75417 | 4079 | 64419218 |
Multiple lentigines syndrome | 10.55 | 9.91 | 5 | 75430 | 195 | 64423102 |
Basophil count abnormal | 10.48 | 9.91 | 3 | 75432 | 26 | 64423271 |
Polymorphic light eruption | 10.48 | 9.91 | 3 | 75432 | 26 | 64423271 |
Acute myeloid leukaemia | 10.45 | 9.91 | 10 | 75425 | 27453 | 64395844 |
Glomerular filtration rate decreased | 10.44 | 9.91 | 48 | 75387 | 19524 | 64403773 |
Impaired healing | 10.42 | 9.91 | 36 | 75399 | 60437 | 64362860 |
Renal artery stenosis | 10.42 | 9.91 | 15 | 75420 | 2954 | 64420343 |
Necrotising soft tissue infection | 10.36 | 9.91 | 5 | 75430 | 203 | 64423094 |
Immunodeficiency | 10.35 | 9.91 | 3 | 75432 | 16121 | 64407176 |
Eye haemorrhage | 10.21 | 9.91 | 27 | 75408 | 8333 | 64414964 |
Multiple organ dysfunction syndrome | 10.19 | 9.91 | 171 | 75264 | 101242 | 64322055 |
Threatened labour | 10.18 | 9.91 | 7 | 75428 | 558 | 64422739 |
Leg amputation | 10.16 | 9.91 | 16 | 75419 | 3411 | 64419886 |
Body mass index abnormal | 10.11 | 9.91 | 5 | 75430 | 214 | 64423083 |
Rhabdomyolysis | 10.08 | 9.91 | 157 | 75278 | 91569 | 64331728 |
Dyspepsia | 10.05 | 9.91 | 54 | 75381 | 80258 | 64343039 |
Ill-defined disorder | 9.98 | 9.91 | 23 | 75412 | 44029 | 64379268 |
Disseminated intravascular coagulation | 9.92 | 9.91 | 14 | 75421 | 32334 | 64390963 |
None
Source | Code | Description |
---|---|---|
ATC | A10AB05 | ALIMENTARY TRACT AND METABOLISM DRUGS USED IN DIABETES INSULINS AND ANALOGUES Insulins and analogues for injection, fast-acting |
ATC | A10AD05 | ALIMENTARY TRACT AND METABOLISM DRUGS USED IN DIABETES INSULINS AND ANALOGUES Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting |
ATC | A10AD06 | ALIMENTARY TRACT AND METABOLISM DRUGS USED IN DIABETES INSULINS AND ANALOGUES Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting |
FDA CS | M0011417 | Insulin |
FDA EPC | N0000175453 | Insulin Analog |
CHEBI has role | CHEBI:35526 | antidiabetic |
FDA EPC | N0000175944 | Insulin |
MeSH PA | D007004 | Hypoglycemic Agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Diabetes mellitus | indication | 73211009 | DOID:9351 |
None
None
None
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Insulin receptor | Kinase | AGONIST | DRUG LABEL | DRUG LABEL |
ID | Source |
---|---|
D04475 | KEGG_DRUG |
4021226 | VUID |
N0000148670 | NUI |
4017559 | VANDF |
4017569 | VANDF |
4019786 | VANDF |
4021226 | VANDF |
4021394 | VANDF |
CHEBI:5931 | CHEBI |
CHEMBL1201496 | ChEMBL_ID |
CHEMBL1201664 | ChEMBL_ID |
7541 | INN_ID |
DB01306 | DRUGBANK_ID |
D933668QVX | UNII |
118984445 | PUBCHEM_CID |
118984375 | PUBCHEM_CID |
DB00030 | DRUGBANK_ID |
253182 | RXNORM |
15636 | MMSL |
17095 | MMSL |
327602 | MMSL |
37703 | MMSL |
4885 | MMSL |
4886 | MMSL |
d00262 | MMSL |
d04369 | MMSL |
d04697 | MMSL |
d04838 | MMSL |
126210001 | SNOMEDCT_US |
325072002 | SNOMEDCT_US |
388452006 | SNOMEDCT_US |
417423002 | SNOMEDCT_US |
420609005 | SNOMEDCT_US |
427292001 | SNOMEDCT_US |
96367001 | SNOMEDCT_US |
D061267 | MESH_DESCRIPTOR_UI |
C0123677 | UMLSCUI |
C0795635 | UMLSCUI |
5186 | INN_ID |
000869 | NDDF |
000870 | NDDF |
006518 | NDDF |
007992 | NDDF |
009607 | NDDF |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-2100 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | BLA | 29 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-2101 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | BLA | 29 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-2200 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | BLA | 27 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-2201 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | BLA | 27 sections |
Fiasp | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-3201 | INJECTION, SOLUTION | 100 [iU] | SUBCUTANEOUS | BLA | 26 sections |
Fiasp | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-3201 | INJECTION, SOLUTION | 100 [iU] | SUBCUTANEOUS | BLA | 26 sections |
Fiasp | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-3204 | INJECTION, SOLUTION | 100 [iU] | SUBCUTANEOUS | BLA | 26 sections |
Fiasp | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-3204 | INJECTION, SOLUTION | 100 [iU] | SUBCUTANEOUS | BLA | 26 sections |
Fiasp | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-3205 | INJECTION, SOLUTION | 100 [iU] | SUBCUTANEOUS | BLA | 26 sections |
Fiasp | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-3205 | INJECTION, SOLUTION | 100 [iU] | SUBCUTANEOUS | BLA | 26 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-3303 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | BLA | 29 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-3685 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | BLA | 27 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-3696 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | BLA | 27 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-6338 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | BLA | 29 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-6339 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | BLA | 29 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0169-7501 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | BLA | 29 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-1664 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | NDA | 29 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-1664 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | NDA | 29 sections |
NovoLog | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-1665 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | NDA | 29 sections |
NovoLog | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-1665 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | NDA | 29 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-1678 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | NDA | 29 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-1678 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | NDA | 29 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-2272 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | NDA | 29 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-2272 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | NDA | 29 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-2273 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | NDA | 29 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-2273 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | NDA | 29 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4074 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | BLA | 27 sections |
NovoLog Mix 70/30 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4085 | INJECTION, SUSPENSION | 100 [iU] | SUBCUTANEOUS | BLA | 27 sections |
NOVOLOG | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4500 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | BLA | 28 sections |
Insulin Aspart | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4955 | INJECTION, SOLUTION | 100 [iU] | INTRAVENOUS | BLA | 28 sections |