pyronaridine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4339 74847-35-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pyronaridine tetraphosphate
  • pyronaridine
  • malaridine
  • Molecular weight: 518.06
  • Formula: C29H32ClN5O2
  • CLOGP: 6.90
  • LIPINSKI: 2
  • HAC: 7
  • HDO: 2
  • TPSA: 73.75
  • ALOGS: -4.59
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P01BF06 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
ANTIMALARIALS
Artemisinin and derivatives, combinations
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000962 Antimalarials
MeSH PA D000977 Antiparasitic Agents
MeSH PA D000981 Antiprotozoal Agents

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Vivax malaria indication 27052006 DOID:12978
Falciparum malaria indication 62676009 DOID:14067




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 0.5 acidic
pKa2 12.0 Basic
pKa3 12.0 Basic
pKa4 5.9 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
76748-86-2 SECONDARY_CAS_RN
C0072768 UMLSCUI
CHEBI:135951 CHEBI
CHEMBL35228 ChEMBL_ID
CHEMBL2095224 ChEMBL_ID
DB12975 DRUGBANK_ID
C027871 MESH_SUPPLEMENTAL_RECORD_UI
10086 IUPHAR_LIGAND_ID
8833 INN_ID
TD3P7Q3SG6 UNII
107771 PUBCHEM_CID

Pharmaceutical products:

None