pyronaridine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4339 74847-35-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pyronaridine tetraphosphate
  • pyronaridine
  • malaridine
  • Molecular weight: 518.06
  • Formula: C29H32ClN5O2
  • CLOGP: 6.90
  • LIPINSKI: 2
  • HAC: 7
  • HDO: 2
  • TPSA: 73.75
  • ALOGS: -4.59
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC P01BF06 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
ANTIMALARIALS
Artemisinin and derivatives, combinations
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000962 Antimalarials
MeSH PA D000977 Antiparasitic Agents
MeSH PA D000981 Antiprotozoal Agents

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Vivax malaria indication 27052006 DOID:12978
Falciparum malaria indication 62676009 DOID:14067

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 0.5 acidic
pKa2 12.0 Basic
pKa3 12.0 Basic
pKa4 5.9 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
2T289F9ACO UNII
76748-86-2 SECONDARY_CAS_RN
CHEMBL35228 ChEMBL_ID
8833 INN_ID
CHEBI:135951 CHEBI
DB12975 DRUGBANK_ID
CHEMBL2095224 ChEMBL_ID
107771 PUBCHEM_CID
10086 IUPHAR_LIGAND_ID
C027871 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None