DrugCentral 2023 ๐
2022 Update-Veterinary Drugs & Uses
Search
Structure ๐
Similarity ๐
Smart API
Redial
About
Download
L1000
FAQ
DrugCentral 2023 ๐
2022 Update-Veterinary Drugs & Uses
Search
Structure ๐
Similarity ๐
Smart API
Redial
About
Download
L1000
FAQ
Scroll
All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
artemether ๐ถ
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
antimalarial agents, artemisinin related compounds
245
71963-77-4
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
artemether
artemos
artenam
artesaph
dihydroartemisinin methyl ether
falcidol
gvither
malartem
beta-Artemether
An artemisinin derivative that is used in the treatment of MALARIA.
Molecular weight: 298.38
Formula: C16H26O5
CLOGP: 3.06
LIPINSKI: 0
HAC: 5
HDO: 0
TPSA: 46.15
ALOGS: -2.81
ROTB: 1
Status: OFP
Legend:
OFP - off patent
OFM - off market
ONP - on patent
Drug dosage:
Dose
Unit
Route
0.28
g
O
0.12
g
P
0.28
g
R
0.28
g
O
ADMET properties:
Show
10
25
50
100
entries
Search:
Property
Value
Reference
MRTD (Maximum Recommended Therapeutic Daily Dose)
6.70 ยตM/kg/day
Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BA (Bioavailability)
58 %
Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
BDDCS (Biopharmaceutical Drug Disposition Classification System)
1
Bocci G, Oprea TI, Benet LZ
S (Water solubility)
0.46 mg/mL
Bocci G, Oprea TI, Benet LZ
Showing 1 to 4 of 4 entries
Previous
1
Next
Approvals:
Show
10
25
50
100
entries
Search:
Date
Agency
Company
Orphan
April 7, 2009
FDA
Showing 1 to 1 of 1 entries
Previous
1
Next
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
Show
10
25
50
100
entries
Search:
Source
Code
Description
ATC
P01BE02
ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
ANTIMALARIALS
Artemisinin and derivatives, plain
ATC
P01BF01
ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
ANTIMALARIALS
Artemisinin and derivatives, combinations
CHEBI has role
CHEBI:38068
antimalarials
FDA EPC
N0000175482
Antimalarial
MeSH PA
D000890
Anti-Infective Agents
MeSH PA
D000962
Antimalarials
MeSH PA
D000977
Antiparasitic Agents
MeSH PA
D000981
Antiprotozoal Agents
Showing 1 to 8 of 8 entries
Previous
1
Next
Drug Use
| Suggest Off label Use Form|
|View source of the data|
Show
10
25
50
100
entries
Search:
Disease
Relation
SNOMED_ID
DOID
Chloroquine Resistant Plasmodium Falciparum Malaria
indication
Torsades de pointes
contraindication
31722008
Hypokalemia
contraindication
43339004
Bradycardia
contraindication
48867003
Prolonged QT interval
contraindication
111975006
Hypomagnesemia
contraindication
190855004
Congenital long QT syndrome
contraindication
442917000
Showing 1 to 7 of 7 entries
Previous
1
Next
๐ถ Veterinary Drug Use
None
๐ถ Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
Show
10
25
50
100
entries
Search:
ID
Source
D8Z
PDB_CHEM_ID
009714
NDDF
18343
RXNORM
18572
MMSL
4028721
VUID
4028721
VANDF
420578008
SNOMEDCT_US
420661005
SNOMEDCT_US
6458
INN_ID
68911
PUBCHEM_CID
Showing 1 to 10 of 20 entries
Previous
1
2
Next
Pharmaceutical products:
Show
10
25
50
100
entries
Search:
Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
COARTEM
HUMAN PRESCRIPTION DRUG LABEL
2
0078-0568
TABLET
20 mg
ORAL
NDA
28 sections
COARTEM
HUMAN PRESCRIPTION DRUG LABEL
2
0078-0568
TABLET
20 mg
ORAL
NDA
28 sections
COARTEM
HUMAN PRESCRIPTION DRUG LABEL
2
0078-0568
TABLET
20 mg
ORAL
NDA
28 sections
COARTEM
HUMAN PRESCRIPTION DRUG LABEL
2
76413-154
TABLET
20 mg
ORAL
NDA
27 sections
Showing 1 to 4 of 4 entries
Previous
1
Next
Search
Structure ๐
Similarity ๐
Smart API
Redial
About
Download
L1000
FAQ
artemether