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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
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L1000
FAQ
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
artemisinin 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
antimalarial agents, artemisinin related compounds
3871
63968-64-9
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
artemisinin
(+)-Artemisinin
arteannuin
artemef
artemisine
artemisinine
antimalarial from Chinese medicinal herb Artemisia annua
Molecular weight: 282.34
Formula: C15H22O5
CLOGP: 2.34
LIPINSKI: 0
HAC: 5
HDO: 0
TPSA: 53.99
ALOGS: -2.35
ROTB: 0
Drug dosage:
Dose
Unit
Route
1
g
O
ADMET properties:
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Property
Value
Reference
BDDCS (Biopharmaceutical Drug Disposition Classification System)
2
Bocci G, Oprea TI, Benet LZ
S (Water solubility)
0.05 mg/mL
Bocci G, Oprea TI, Benet LZ
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
P01BE01
ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
ANTIMALARIALS
Artemisinin and derivatives, plain
ATC
P01BF07
ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
ANTIMALARIALS
Artemisinin and derivatives, combinations
ATC
P01BF08
ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
ANTIMALARIALS
Artemisinin and derivatives, combinations
CHEBI has role
CHEBI:38068
antimalarials
CHEBI has role
CHEBI:76924
plant metabolites
MeSH PA
D000890
Anti-Infective Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Falciparum malaria
indication
62676009
DOID:14067
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Cytochrome P450 1A2
Enzyme
P05177
CP1A2_HUMAN
IC50
5.70
DRUG MATRIX
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External reference:
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ID
Source
019140
NDDF
2367409
RXNORM
5954
INN_ID
68827
PUBCHEM_CID
895350006
SNOMEDCT_US
96106001
SNOMEDCT_US
9954
IUPHAR_LIGAND_ID
9RMU91N5K2
UNII
C0052430
UMLSCUI
C031327
MESH_SUPPLEMENTAL_RECORD_UI
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
ArtemiC Rescue
HUMAN OTC DRUG LABEL
4
83278-001
SPRAY, SUSPENSION
0.60 g
ORAL
unapproved drug other
11 sections
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artemisinin