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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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Structure 🔎
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
ethacridine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
acridine derivatives
3194
442-16-0
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
ethacridine
etakridin
ethacridine lactate
A topically applied anti-infective agent.
Molecular weight: 253.31
Formula: C15H15N3O
CLOGP: 3.37
LIPINSKI: 0
HAC: 4
HDO: 2
TPSA: 74.16
ALOGS: -3.58
ROTB: 2
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
B05CA08
BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
IRRIGATING SOLUTIONS
Antiinfectives
ATC
D08AA01
DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Acridine derivatives
MeSH PA
D000890
Anti-Infective Agents
MeSH PA
D000891
Anti-Infective Agents, Local
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
10.96
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Telomerase reverse transcriptase
Enzyme
O14746
TERT_HUMAN
IC50
5.09
CHEMBL
Reverse transcriptase/RNaseH
Enzyme
Q72547_9HIV1
IC50
4.70
CHEMBL
Reverse transcriptase
Enzyme
Q9WKE8_9HIV1
IC50
4.70
CHEMBL
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External reference:
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ID
Source
005540
NDDF
005541
NDDF
1783
INN_ID
2017
PUBCHEM_CID
4106
RXNORM
6402-23-9
SECONDARY_CAS_RN
711320003
SNOMEDCT_US
715469007
SNOMEDCT_US
C0014960
UMLSCUI
CHEBI:135032
CHEBI
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Pharmaceutical products:
None
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ethacridine