suxibuzone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anti-inflammatory analgesics, phenylbutazone derivatives 2547 27470-51-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • suxibuzone
  • calibene
  • danilon
  • suxibutazone
  • 4-Hydroxymethylbutazolidine hemisuccinate
  • Molecular weight: 438.48
  • Formula: C24H26N2O6
  • CLOGP: 3.66
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 1
  • TPSA: 104.22
  • ALOGS: -4.12
  • ROTB: 11

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M02AA22 MUSCULO-SKELETAL SYSTEM
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
Antiinflammatory preparations, non-steroids for topical use
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents
CHEBI has role CHEBI:35475 non-steroidal anti-inflammatory agent
CHEBI has role CHEBI:35842 anti-rheumatic drugs
CHEBI has role CHEBI:49110 peripheral nervous system drugs
CHEBI has role CHEBI:50266 Prodrugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.37 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01289 KEGG_DRUG
C0075667 UMLSCUI
CHEBI:32173 CHEBI
CHEMBL1414320 ChEMBL_ID
DB13232 DRUGBANK_ID
C003371 MESH_SUPPLEMENTAL_RECORD_UI
2955 INN_ID
86TDZ5WP2B UNII
5362 PUBCHEM_CID

Pharmaceutical products:

None