Stem definition | Drug id | CAS RN |
---|---|---|
anti-inflammatory agents, ibufenac derivatives | 1141 | 5728-52-9 |
None
None
None
None
None
None
None
Source | Code | Description |
---|---|---|
ATC | M02AA08 | MUSCULO-SKELETAL SYSTEM TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN Antiinflammatory preparations, non-steroids for topical use |
MeSH PA | D000700 | Analgesics |
MeSH PA | D018712 | Analgesics, Non-Narcotic |
MeSH PA | D000893 | Anti-Inflammatory Agents |
MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
MeSH PA | D018501 | Antirheumatic Agents |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D018689 | Sensory System Agents |
CHEBI has role | CHEBI:35475 | non-steroidal anti-inflammatory agent |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Pain | indication | 22253000 | |
Osteoarthritis | indication | 396275006 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.4 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 | Enzyme | INHIBITOR | KEGG DRUG | KEGG DRUG | |||||
Prostaglandin G/H synthase 1 | Enzyme | INHIBITOR | IC50 | 6.05 | DRUG MATRIX | KEGG DRUG |
ID | Source |
---|---|
D01675 | KEGG_DRUG |
C0877860 | UMLSCUI |
CHEBI:31597 | CHEBI |
BP4 | PDB_CHEM_ID |
CHEMBL413965 | ChEMBL_ID |
DB07477 | DRUGBANK_ID |
3332 | PUBCHEM_CID |
C012776 | MESH_SUPPLEMENTAL_RECORD_UI |
5831 | INN_ID |
94WNJ5U8L7 | UNII |
225536 | RXNORM |
003698 | NDDF |
350320002 | SNOMEDCT_US |
396051001 | SNOMEDCT_US |
None