picotamide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2161 32828-81-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • picotamide
  • picotamide monohydrate
  • picotamide hydrate
Picotamide is an antiplatelet drug with dual mechanism of action it inhibits thromboxane A2 synthase and antagonizes the pharmacological responses mediated by thromboxane A2 receptor.
  • Molecular weight: 376.42
  • Formula: C21H20N4O3
  • CLOGP: 1.10
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 2
  • TPSA: 93.21
  • ALOGS: -4.35
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC B01AC03 BLOOD AND BLOOD FORMING ORGANS
ANTITHROMBOTIC AGENTS
ANTITHROMBOTIC AGENTS
Platelet aggregation inhibitors excl. heparin
MeSH PA D006401 Hematologic Agents
MeSH PA D010975 Platelet Aggregation Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.73 acidic
pKa2 12.39 acidic
pKa3 5.2 Basic
pKa4 4.59 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07140 KEGG_DRUG
C0071043 UMLSCUI
CHEBI:93175 CHEBI
CHEMBL1257015 ChEMBL_ID
DB13327 DRUGBANK_ID
C011581 MESH_SUPPLEMENTAL_RECORD_UI
4814 PUBCHEM_CID
11379 IUPHAR_LIGAND_ID
80530-63-8 SECONDARY_CAS_RN
654G2VCI4Q UNII

Pharmaceutical products:

None