ditazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
929 18471-20-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ditazole
  • ageroplas
  • diethylphenazol
  • ditazol
  • Molecular weight: 324.38
  • Formula: C19H20N2O3
  • CLOGP: 2.65
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 69.73
  • ALOGS: -3.35
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,ITK,JAK2,MAP3K21,MAP3K7,MAPK7,NTRK2,PDK2,PDK4,PIK3CB,PIK3CG,PRKDC,SIK2,SIK3,STK33,TEK,TTK 32
kinase-selectivity-class AXL,BRAF,ERBB2,GRK2 4
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC B01AC01 BLOOD AND BLOOD FORMING ORGANS
ANTITHROMBOTIC AGENTS
ANTITHROMBOTIC AGENTS
Platelet aggregation inhibitors excl. heparin
CHEBI has role CHEBI:50249 anticoagulant

Related Drugs by ATC class:

B01AC Platelet aggregation inhibitors excl. heparin 24 drugs
abciximabacetylsalicylic acidaloxiprinberaprostcangrelorcarbasalate calciumcilostazolclopidogrelcloricromendipyridamoleepoprostenoleptifibatide show all 24 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07138 KEGG_DRUG
C0012777 UMLSCUI
CHEBI:135383 CHEBI
CHEMBL2104306 ChEMBL_ID
DB08994 DRUGBANK_ID
29088 PUBCHEM_CID
2603 INN_ID
H2BQI5Z8FT UNII
C084774 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None