methylestrenolone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
steroids, progestogens 1970 514-61-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • methylestrenolone
  • normethandrone
  • matronal
  • metalutin
  • methalutin
  • methylnortestosteron
  • normetandrone
  • normethandrolone
  • normethanedrolone
  • normethisterone
  • methylnortestosterone
was MH 1963-92; METHYLESTRENOLONE & METHYLNORTESTOSTERONE were see NORMETHANDROLONE 1963-92; use ESTRENES to search NORMETHANDROLONE 1966-92
  • Molecular weight: 288.43
  • Formula: C19H28O2
  • CLOGP: 3.41
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 37.30
  • ALOGS: -3.98
  • ROTB: 0

Drug dosage:

DoseUnitRoute
5 mg O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,CAMK2D,CDK5,EIF2AK3,ERBB2,GRK2,ITK,MAPK10,NTRK2,PDK1,PDK2,PDK4,PRKDC 15
kinase-selectivity-class EIF2AK3,GRK2 2
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC G03DC31 GENITO URINARY SYSTEM AND SEX HORMONES
SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
PROGESTOGENS
Estren derivatives
ATC G03FA05 GENITO URINARY SYSTEM AND SEX HORMONES
SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
PROGESTOGENS AND ESTROGENS IN COMBINATION
Progestogens and estrogens, fixed combinations
CHEBI has role CHEBI:50114 estrogen

Related Drugs by ATC class:

G03DC Estren derivatives 5 drugs
allylestrenolethisteroneetynodiollynestrenolnorethisterone
G03FA Progestogens and estrogens, fixed combinations 15 drugs
dienogestdrospirenonedydrogesteroneethisteroneetynodiolhydroxyprogesterone caproatelevonorgestrellynestrenolmedroxyprogesteronemegestrol acetatenorethisteronenorethynodrel show all 15 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0650248 UMLSCUI
CHEBI:34896 CHEBI
CHEMBL2106801 ChEMBL_ID
5284597 PUBCHEM_CID
DB13533 DRUGBANK_ID
C073330 MESH_SUPPLEMENTAL_RECORD_UI
725690007 SNOMEDCT_US
743F1Z557A UNII

Pharmaceutical products:

None