Molfile
Inchi
Smiles
Synonyms:
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megestrol acetate
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magestin
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megestryl acetate
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niagestin
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Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
- Molecular weight: 384.52
- Formula: C24H32O4
- CLOGP: 3.77
- LIPINSKI: 0
- HAC: 4
- HDO: 0
- TPSA: 60.44
- ALOGS: -5.06
- ROTB: 3
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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