Stem definition | Drug id | CAS RN |
---|---|---|
1883 | 22204-53-1 |
Dose | Unit | Route |
---|---|---|
0.50 | g | O |
0.50 | g | R |
0.50 | g | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.12 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.50 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 108.57 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 99 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 0.09 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 0.07 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.00 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 16.63 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
March 11, 1976 | FDA | ROCHE PALO |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
C-reactive protein abnormal | 405.87 | 10.10 | 659 | 232788 | 45437 | 63210138 |
Death | 400.05 | 10.10 | 473 | 232974 | 373908 | 62881667 |
Pharyngitis | 371.05 | 10.10 | 413 | 233034 | 19730 | 63235845 |
Red blood cell sedimentation rate abnormal | 366.81 | 10.10 | 407 | 233040 | 19375 | 63236200 |
Ankylosing spondylitis | 312.12 | 10.10 | 279 | 233168 | 10195 | 63245380 |
Rheumatoid arthritis | 270.49 | 10.10 | 1727 | 231720 | 252092 | 63003483 |
Drug hypersensitivity | 260.09 | 10.10 | 1993 | 231454 | 308694 | 62946881 |
Musculoskeletal stiffness | 258.60 | 10.10 | 1351 | 232096 | 183267 | 63072308 |
Psoriatic arthropathy | 258.16 | 10.10 | 832 | 232615 | 90688 | 63164887 |
Deafness transitory | 249.76 | 10.10 | 129 | 233318 | 1841 | 63253734 |
Fibromyalgia | 234.93 | 10.10 | 740 | 232707 | 79680 | 63175895 |
Gastrointestinal pain | 227.37 | 10.10 | 227 | 233220 | 9549 | 63246026 |
Synovitis | 195.36 | 10.10 | 1266 | 232181 | 185652 | 63069923 |
Neutropenia | 191.00 | 10.10 | 217 | 233230 | 174788 | 63080787 |
Arthralgia | 190.33 | 10.10 | 3044 | 230403 | 566666 | 62688909 |
Anaemia | 169.99 | 10.10 | 534 | 232913 | 292896 | 62962679 |
Febrile neutropenia | 163.66 | 10.10 | 118 | 233329 | 118331 | 63137244 |
Rheumatoid nodule | 154.68 | 10.10 | 248 | 233199 | 16907 | 63238668 |
Gait inability | 151.58 | 10.10 | 484 | 232963 | 52475 | 63203100 |
C-reactive protein increased | 150.79 | 10.10 | 719 | 232728 | 93988 | 63161587 |
Shoulder arthroplasty | 150.79 | 10.10 | 122 | 233325 | 3880 | 63251695 |
Joint swelling | 147.81 | 10.10 | 1847 | 231600 | 325819 | 62929756 |
Hyponatraemia | 145.01 | 10.10 | 119 | 233328 | 111781 | 63143794 |
Disease progression | 141.92 | 10.10 | 145 | 233302 | 122613 | 63132962 |
Obesity | 140.19 | 10.10 | 328 | 233119 | 29624 | 63225951 |
Hypoaesthesia | 139.35 | 10.10 | 1078 | 232369 | 167315 | 63088260 |
Body height below normal | 138.00 | 10.10 | 91 | 233356 | 2092 | 63253483 |
Impaired work ability | 136.65 | 10.10 | 237 | 233210 | 17238 | 63238337 |
Cardiac failure | 136.50 | 10.10 | 79 | 233368 | 89063 | 63166512 |
Pancytopenia | 135.95 | 10.10 | 95 | 233352 | 96838 | 63158737 |
Abdominal pain upper | 135.09 | 10.10 | 1254 | 232193 | 205190 | 63050385 |
Pain in extremity | 134.61 | 10.10 | 1833 | 231614 | 329653 | 62925922 |
Polyarthritis | 132.83 | 10.10 | 175 | 233272 | 9971 | 63245604 |
Injury | 129.87 | 10.10 | 574 | 232873 | 72673 | 63182902 |
Thrombocytopenia | 129.39 | 10.10 | 223 | 233224 | 150934 | 63104641 |
Arthritis | 128.97 | 10.10 | 798 | 232649 | 115123 | 63140452 |
Arthropathy | 128.84 | 10.10 | 1375 | 232072 | 233417 | 63022158 |
Human antichimeric antibody positive | 127.07 | 10.10 | 79 | 233368 | 1635 | 63253940 |
Migraine | 126.86 | 10.10 | 730 | 232717 | 102616 | 63152959 |
Inflammation | 124.06 | 10.10 | 615 | 232832 | 81658 | 63173917 |
Foot operation | 122.52 | 10.10 | 142 | 233305 | 7089 | 63248486 |
Pyrexia | 122.50 | 10.10 | 1123 | 232324 | 469355 | 62786220 |
Leukopenia | 121.94 | 10.10 | 66 | 233381 | 77224 | 63178351 |
Joint destruction | 121.73 | 10.10 | 132 | 233315 | 6120 | 63249455 |
Psoriasis | 119.95 | 10.10 | 634 | 232813 | 86323 | 63169252 |
Drug ineffective | 119.37 | 10.10 | 4829 | 228618 | 1039936 | 62215639 |
Musculoskeletal disorder | 118.05 | 10.10 | 245 | 233202 | 20399 | 63235176 |
Sepsis | 117.75 | 10.10 | 241 | 233206 | 152882 | 63102693 |
Pneumonia | 117.73 | 10.10 | 1093 | 232354 | 455674 | 62799901 |
Toothache | 117.07 | 10.10 | 234 | 233213 | 18965 | 63236610 |
Nerve injury | 114.23 | 10.10 | 161 | 233286 | 9785 | 63245790 |
Grip strength decreased | 114.22 | 10.10 | 253 | 233194 | 22034 | 63233541 |
Dislocation of vertebra | 113.14 | 10.10 | 149 | 233298 | 8486 | 63247089 |
Pain | 111.38 | 10.10 | 3533 | 229914 | 737095 | 62518480 |
Dyspnoea | 106.65 | 10.10 | 1751 | 231696 | 659562 | 62596013 |
Musculoskeletal pain | 105.63 | 10.10 | 640 | 232807 | 91637 | 63163938 |
Malignant neoplasm progression | 105.56 | 10.10 | 88 | 233359 | 82033 | 63173542 |
Drug intolerance | 100.32 | 10.10 | 1643 | 231804 | 307018 | 62948557 |
Drug interaction | 99.08 | 10.10 | 469 | 232978 | 228662 | 63026913 |
Joint laxity | 98.99 | 10.10 | 78 | 233369 | 2386 | 63253189 |
Mobility decreased | 98.72 | 10.10 | 773 | 232674 | 120386 | 63135189 |
Gastric ulcer | 97.35 | 10.10 | 249 | 233198 | 23788 | 63231787 |
Exposure during pregnancy | 97.23 | 10.10 | 273 | 233174 | 155274 | 63100301 |
Cardiac failure congestive | 97.15 | 10.10 | 118 | 233329 | 92315 | 63163260 |
Prescribed overdose | 96.69 | 10.10 | 311 | 233136 | 33842 | 63221733 |
Systemic lupus erythematosus rash | 96.36 | 10.10 | 74 | 233373 | 2178 | 63253397 |
Cholecystitis chronic | 95.07 | 10.10 | 151 | 233296 | 10210 | 63245365 |
Drug tolerance | 94.30 | 10.10 | 122 | 233325 | 6827 | 63248748 |
Multiple fractures | 92.37 | 10.10 | 135 | 233312 | 8483 | 63247092 |
Loose body in joint | 89.63 | 10.10 | 57 | 233390 | 1229 | 63254346 |
Nephrolithiasis | 89.32 | 10.10 | 348 | 233099 | 41636 | 63213939 |
Bradycardia | 88.65 | 10.10 | 83 | 233364 | 73144 | 63182431 |
Femur fracture | 87.12 | 10.10 | 344 | 233103 | 41412 | 63214163 |
Dizziness | 86.89 | 10.10 | 2131 | 231316 | 427794 | 62827781 |
Neck pain | 84.62 | 10.10 | 489 | 232958 | 68829 | 63186746 |
Seronegative arthritis | 83.11 | 10.10 | 87 | 233360 | 3872 | 63251703 |
Functional gastrointestinal disorder | 83.05 | 10.10 | 90 | 233357 | 4169 | 63251406 |
Wound infection | 80.78 | 10.10 | 216 | 233231 | 21194 | 63234381 |
Joint range of motion decreased | 80.04 | 10.10 | 282 | 233165 | 32146 | 63223429 |
Wheelchair user | 79.66 | 10.10 | 107 | 233340 | 6212 | 63249363 |
Blepharospasm | 79.39 | 10.10 | 104 | 233343 | 5892 | 63249683 |
Platelet count decreased | 77.71 | 10.10 | 197 | 233250 | 115925 | 63139650 |
Ear infection | 75.09 | 10.10 | 309 | 233138 | 37904 | 63217671 |
Hypotension | 73.72 | 10.10 | 644 | 232803 | 271960 | 62983615 |
Pseudoporphyria | 73.19 | 10.10 | 28 | 233419 | 183 | 63255392 |
Maternal exposure during pregnancy | 73.10 | 10.10 | 491 | 232956 | 219571 | 63036004 |
Osteoporosis | 70.31 | 10.10 | 405 | 233042 | 56933 | 63198642 |
Renal impairment | 69.66 | 10.10 | 137 | 233310 | 88218 | 63167357 |
Bursitis | 69.25 | 10.10 | 295 | 233152 | 36746 | 63218829 |
Foetal exposure during pregnancy | 67.68 | 10.10 | 17 | 233430 | 31945 | 63223630 |
Hypomagnesaemia | 67.58 | 10.10 | 12 | 233435 | 28725 | 63226850 |
Tenosynovitis stenosans | 67.20 | 10.10 | 72 | 233375 | 3292 | 63252283 |
Multiple organ dysfunction syndrome | 66.75 | 10.10 | 66 | 233381 | 56686 | 63198889 |
Lip swelling | 66.49 | 10.10 | 258 | 233189 | 30805 | 63224770 |
Dehydration | 66.32 | 10.10 | 370 | 233077 | 172984 | 63082591 |
Mycotic allergy | 66.03 | 10.10 | 43 | 233404 | 967 | 63254608 |
Cardiospasm | 65.30 | 10.10 | 55 | 233392 | 1852 | 63253723 |
Tenosynovitis | 64.47 | 10.10 | 151 | 233296 | 13644 | 63241931 |
Adjustment disorder with depressed mood | 64.18 | 10.10 | 126 | 233321 | 10078 | 63245497 |
Amnesia | 63.89 | 10.10 | 386 | 233061 | 55199 | 63200376 |
Drug abuse | 63.85 | 10.10 | 105 | 233342 | 72413 | 63183162 |
Enthesopathy | 63.69 | 10.10 | 114 | 233333 | 8500 | 63247075 |
Orthostatic hypotension | 62.94 | 10.10 | 27 | 233420 | 36133 | 63219442 |
Palmoplantar keratoderma | 62.86 | 10.10 | 55 | 233392 | 1952 | 63253623 |
Ulcer | 62.69 | 10.10 | 225 | 233222 | 25882 | 63229693 |
Foot deformity | 62.63 | 10.10 | 235 | 233212 | 27618 | 63227957 |
Respiratory failure | 61.27 | 10.10 | 182 | 233265 | 101676 | 63153899 |
Liver injury | 60.73 | 10.10 | 406 | 233041 | 60114 | 63195461 |
Premature delivery | 60.56 | 10.10 | 18 | 233429 | 30263 | 63225312 |
Pruritus genital | 60.56 | 10.10 | 61 | 233386 | 2593 | 63252982 |
Lip dry | 60.32 | 10.10 | 158 | 233289 | 15312 | 63240263 |
Joint effusion | 60.26 | 10.10 | 168 | 233279 | 16892 | 63238683 |
Bone density decreased | 59.82 | 10.10 | 152 | 233295 | 14460 | 63241115 |
Hospitalisation | 59.54 | 10.10 | 141 | 233306 | 84940 | 63170635 |
Synovial fluid analysis | 59.37 | 10.10 | 58 | 233389 | 2375 | 63253200 |
Disability | 59.30 | 10.10 | 175 | 233272 | 18172 | 63237403 |
Therapy non-responder | 58.92 | 10.10 | 479 | 232968 | 75422 | 63180153 |
Drug tolerance decreased | 58.72 | 10.10 | 169 | 233278 | 17304 | 63238271 |
Antibody test positive | 57.74 | 10.10 | 60 | 233387 | 2647 | 63252928 |
Respiratory tract congestion | 57.55 | 10.10 | 170 | 233277 | 17662 | 63237913 |
Neutrophil count decreased | 57.18 | 10.10 | 74 | 233373 | 56332 | 63199243 |
Adrenal insufficiency | 57.07 | 10.10 | 170 | 233277 | 17745 | 63237830 |
White blood cell count decreased | 57.03 | 10.10 | 290 | 233157 | 138814 | 63116761 |
Facet joint syndrome | 56.87 | 10.10 | 133 | 233314 | 12005 | 63243570 |
Gamma-glutamyltransferase increased | 56.75 | 10.10 | 27 | 233420 | 34004 | 63221571 |
Renal failure | 56.13 | 10.10 | 232 | 233215 | 117420 | 63138155 |
Red blood cell sedimentation rate increased | 56.12 | 10.10 | 314 | 233133 | 43668 | 63211907 |
Red blood cell sedimentation rate | 54.89 | 10.10 | 78 | 233369 | 4776 | 63250799 |
Hypoglycaemia | 53.78 | 10.10 | 86 | 233361 | 59979 | 63195596 |
Impaired healing | 53.59 | 10.10 | 595 | 232852 | 101947 | 63153628 |
Drug specific antibody | 53.50 | 10.10 | 54 | 233393 | 2301 | 63253274 |
Deep vein thrombosis postoperative | 52.64 | 10.10 | 124 | 233323 | 11245 | 63244330 |
Posterior reversible encephalopathy syndrome | 51.62 | 10.10 | 3 | 233444 | 17342 | 63238233 |
Bunion operation | 51.29 | 10.10 | 41 | 233406 | 1281 | 63254294 |
Constipation | 51.24 | 10.10 | 554 | 232893 | 224389 | 63031186 |
Confusional state | 51.15 | 10.10 | 589 | 232858 | 235791 | 63019784 |
Drug resistance | 50.93 | 10.10 | 11 | 233436 | 22922 | 63232653 |
Intestinal diaphragm disease | 50.73 | 10.10 | 18 | 233429 | 92 | 63255483 |
Neuropathy peripheral | 50.06 | 10.10 | 231 | 233216 | 113436 | 63142139 |
Scleritis | 49.85 | 10.10 | 71 | 233376 | 4357 | 63251218 |
Sleep terror | 49.43 | 10.10 | 55 | 233392 | 2625 | 63252950 |
Juvenile idiopathic arthritis | 49.26 | 10.10 | 61 | 233386 | 3265 | 63252310 |
Pleuritic pain | 49.12 | 10.10 | 98 | 233349 | 7931 | 63247644 |
Hyperkalaemia | 49.11 | 10.10 | 77 | 233370 | 54126 | 63201449 |
Device expulsion | 47.93 | 10.10 | 35 | 233412 | 34887 | 63220688 |
Fear of injection | 46.93 | 10.10 | 90 | 233357 | 7074 | 63248501 |
Peripheral swelling | 46.84 | 10.10 | 1295 | 232152 | 264647 | 62990928 |
Peripheral venous disease | 46.61 | 10.10 | 144 | 233303 | 15333 | 63240242 |
Limb discomfort | 46.10 | 10.10 | 224 | 233223 | 29492 | 63226083 |
Pulmonary arterial hypertension | 45.92 | 10.10 | 13 | 233434 | 22564 | 63233011 |
Neovascularisation | 45.47 | 10.10 | 36 | 233411 | 1109 | 63254466 |
Nodule | 44.48 | 10.10 | 174 | 233273 | 20852 | 63234723 |
Arthrodesis | 44.13 | 10.10 | 53 | 233394 | 2748 | 63252827 |
Myelosuppression | 44.04 | 10.10 | 16 | 233431 | 23687 | 63231888 |
Memory impairment | 44.01 | 10.10 | 581 | 232866 | 103677 | 63151898 |
Colitis | 43.90 | 10.10 | 69 | 233378 | 48459 | 63207116 |
Hypervolaemia | 43.74 | 10.10 | 25 | 233422 | 28388 | 63227187 |
Wrist deformity | 43.28 | 10.10 | 46 | 233401 | 2084 | 63253491 |
Neoplasm progression | 43.25 | 10.10 | 42 | 233405 | 36386 | 63219189 |
Tendonitis | 42.87 | 10.10 | 164 | 233283 | 19451 | 63236124 |
Respiratory distress | 42.86 | 10.10 | 37 | 233410 | 33914 | 63221661 |
Sopor | 42.85 | 10.10 | 14 | 233433 | 22150 | 63233425 |
Ascites | 42.77 | 10.10 | 52 | 233395 | 40676 | 63214899 |
Pulmonary hypertension | 42.70 | 10.10 | 44 | 233403 | 37079 | 63218496 |
Creatinine renal clearance decreased | 42.55 | 10.10 | 5 | 233442 | 16303 | 63239272 |
Dysstasia | 42.24 | 10.10 | 172 | 233275 | 20994 | 63234581 |
Synovial cyst | 42.16 | 10.10 | 108 | 233339 | 10325 | 63245250 |
Osteoporotic fracture | 42.07 | 10.10 | 60 | 233387 | 3686 | 63251889 |
Oedema | 42.04 | 10.10 | 546 | 232901 | 97076 | 63158499 |
International normalised ratio increased | 42.01 | 10.10 | 66 | 233381 | 46359 | 63209216 |
Hypoxia | 41.90 | 10.10 | 99 | 233348 | 59693 | 63195882 |
Contraindicated product administered | 41.80 | 10.10 | 1072 | 232375 | 216576 | 63038999 |
Paraesthesia | 41.80 | 10.10 | 810 | 232637 | 156156 | 63099419 |
Autoimmune disorder | 41.21 | 10.10 | 148 | 233299 | 17029 | 63238546 |
Emotional distress | 40.61 | 10.10 | 231 | 233216 | 32318 | 63223257 |
Cerebrovascular accident | 40.51 | 10.10 | 232 | 233215 | 107792 | 63147783 |
Immunisation | 40.01 | 10.10 | 34 | 233413 | 1159 | 63254416 |
Uveitis | 39.87 | 10.10 | 119 | 233328 | 12434 | 63243141 |
Angioedema | 39.57 | 10.10 | 307 | 233140 | 47658 | 63207917 |
Hunger | 39.53 | 10.10 | 71 | 233376 | 5308 | 63250267 |
Therapeutic response decreased | 39.29 | 10.10 | 372 | 233075 | 61153 | 63194422 |
Gastric ulcer haemorrhage | 38.94 | 10.10 | 67 | 233380 | 4841 | 63250734 |
Tension headache | 38.81 | 10.10 | 69 | 233378 | 5117 | 63250458 |
Encephalopathy | 38.80 | 10.10 | 51 | 233396 | 38569 | 63217006 |
Choanal stenosis | 38.70 | 10.10 | 11 | 233436 | 22 | 63255553 |
Cardiac arrest | 38.45 | 10.10 | 192 | 233255 | 92353 | 63163222 |
Therapeutic product effect decreased | 38.42 | 10.10 | 956 | 232491 | 192231 | 63063344 |
Pulmonary congestion | 38.37 | 10.10 | 146 | 233301 | 17272 | 63238303 |
Seizure | 37.75 | 10.10 | 309 | 233138 | 132325 | 63123250 |
Pemphigus | 36.97 | 10.10 | 465 | 232982 | 183261 | 63072314 |
Condition aggravated | 36.86 | 10.10 | 1820 | 231627 | 400397 | 62855178 |
Swelling face | 36.74 | 10.10 | 376 | 233071 | 63099 | 63192476 |
Deafness | 36.70 | 10.10 | 147 | 233300 | 17810 | 63237765 |
Sedation complication | 36.66 | 10.10 | 4 | 233443 | 13818 | 63241757 |
Electrolyte imbalance | 36.55 | 10.10 | 14 | 233433 | 20062 | 63235513 |
Cartilage atrophy | 36.42 | 10.10 | 16 | 233431 | 155 | 63255420 |
Off label use | 36.29 | 10.10 | 2070 | 231377 | 672392 | 62583183 |
Acute respiratory failure | 36.24 | 10.10 | 44 | 233403 | 34441 | 63221134 |
Bone disorder | 36.18 | 10.10 | 165 | 233282 | 21161 | 63234414 |
Duodenal ulcer haemorrhage | 36.15 | 10.10 | 45 | 233402 | 2422 | 63253153 |
Cytokine release syndrome | 35.87 | 10.10 | 5 | 233442 | 14309 | 63241266 |
Dry mouth | 35.87 | 10.10 | 441 | 233006 | 77422 | 63178153 |
Osteonecrosis of jaw | 35.68 | 10.10 | 46 | 233401 | 35077 | 63220498 |
Syncope | 35.49 | 10.10 | 269 | 233178 | 117116 | 63138459 |
Haematemesis | 35.45 | 10.10 | 212 | 233235 | 30200 | 63225375 |
Walking aid user | 35.38 | 10.10 | 103 | 233344 | 10614 | 63244961 |
Urticaria | 35.23 | 10.10 | 828 | 232619 | 164974 | 63090601 |
Rheumatoid lung | 35.19 | 10.10 | 56 | 233391 | 3792 | 63251783 |
Right ventricular failure | 34.77 | 10.10 | 10 | 233437 | 17178 | 63238397 |
Abnormal loss of weight | 34.68 | 10.10 | 70 | 233377 | 5712 | 63249863 |
Carotid artery occlusion | 34.55 | 10.10 | 62 | 233385 | 4632 | 63250943 |
Hepatic function abnormal | 34.37 | 10.10 | 52 | 233395 | 37090 | 63218485 |
Premature baby | 33.74 | 10.10 | 17 | 233430 | 20718 | 63234857 |
Feeding disorder | 33.66 | 10.10 | 117 | 233330 | 13245 | 63242330 |
Cerebral haemorrhage | 33.59 | 10.10 | 38 | 233409 | 30691 | 63224884 |
Myelodysplastic syndrome | 33.43 | 10.10 | 10 | 233437 | 16744 | 63238831 |
Electrocardiogram QT prolonged | 33.23 | 10.10 | 110 | 233337 | 59420 | 63196155 |
Iritis | 32.96 | 10.10 | 49 | 233398 | 3126 | 63252449 |
Tooth infection | 32.93 | 10.10 | 142 | 233305 | 17778 | 63237797 |
Hyperglycaemia | 32.92 | 10.10 | 65 | 233382 | 41802 | 63213773 |
Blood creatine phosphokinase increased | 32.86 | 10.10 | 38 | 233409 | 30392 | 63225183 |
Macular degeneration | 32.72 | 10.10 | 25 | 233422 | 24351 | 63231224 |
Mucosal inflammation | 32.64 | 10.10 | 78 | 233369 | 46850 | 63208725 |
Atrial fibrillation | 32.61 | 10.10 | 273 | 233174 | 116363 | 63139212 |
Dactylitis | 32.57 | 10.10 | 44 | 233403 | 2568 | 63253007 |
Alanine aminotransferase abnormal | 32.52 | 10.10 | 59 | 233388 | 4445 | 63251130 |
Tenderness | 32.06 | 10.10 | 166 | 233281 | 22412 | 63233163 |
Fracture delayed union | 32.05 | 10.10 | 42 | 233405 | 2380 | 63253195 |
Psychotic disorder | 31.28 | 10.10 | 29 | 233418 | 25683 | 63229892 |
Blood parathyroid hormone decreased | 31.27 | 10.10 | 93 | 233354 | 9698 | 63245877 |
Atrial tachycardia | 31.20 | 10.10 | 56 | 233391 | 4184 | 63251391 |
Hepatic cytolysis | 31.10 | 10.10 | 9 | 233438 | 15398 | 63240177 |
Feeling jittery | 30.90 | 10.10 | 114 | 233333 | 13289 | 63242286 |
Neurotoxicity | 30.68 | 10.10 | 12 | 233435 | 16978 | 63238597 |
Soft tissue injury | 30.63 | 10.10 | 34 | 233413 | 1618 | 63253957 |
Palmar-plantar erythrodysaesthesia syndrome | 30.39 | 10.10 | 24 | 233423 | 22991 | 63232584 |
Blood creatinine increased | 30.14 | 10.10 | 194 | 233253 | 87650 | 63167925 |
Knee arthroplasty | 29.90 | 10.10 | 318 | 233129 | 53888 | 63201687 |
Tachycardia | 29.77 | 10.10 | 284 | 233163 | 117872 | 63137703 |
Acute kidney injury | 29.77 | 10.10 | 739 | 232708 | 262676 | 62992899 |
Plasma cell myeloma | 29.76 | 10.10 | 54 | 233393 | 35851 | 63219724 |
Full blood count decreased | 29.76 | 10.10 | 31 | 233416 | 25993 | 63229582 |
Ankle arthroplasty | 29.71 | 10.10 | 35 | 233412 | 1778 | 63253797 |
Taste disorder | 29.67 | 10.10 | 114 | 233333 | 13548 | 63242027 |
Tongue disorder | 29.63 | 10.10 | 96 | 233351 | 10484 | 63245091 |
Disability assessment scale score increased | 29.50 | 10.10 | 47 | 233400 | 3186 | 63252389 |
Pain of skin | 29.42 | 10.10 | 102 | 233345 | 11532 | 63244043 |
Infection | 29.31 | 10.10 | 1074 | 232373 | 228099 | 63027476 |
Serum sickness-like reaction | 29.22 | 10.10 | 20 | 233427 | 490 | 63255085 |
Bone marrow failure | 29.09 | 10.10 | 39 | 233408 | 29251 | 63226324 |
Wrong technique in product usage process | 29.06 | 10.10 | 124 | 233323 | 62216 | 63193359 |
Chronic obstructive pulmonary disease | 29.03 | 10.10 | 125 | 233322 | 62561 | 63193014 |
Oedema peripheral | 28.99 | 10.10 | 506 | 232941 | 189005 | 63066570 |
Product dose omission issue | 28.79 | 10.10 | 649 | 232798 | 233664 | 63021911 |
Agranulocytosis | 28.67 | 10.10 | 30 | 233417 | 25104 | 63230471 |
Smear cervix abnormal | 28.51 | 10.10 | 44 | 233403 | 2902 | 63252673 |
Weight decreased | 28.42 | 10.10 | 1267 | 232180 | 275531 | 62980044 |
Gastrooesophageal reflux disease | 28.39 | 10.10 | 502 | 232945 | 95137 | 63160438 |
Limb deformity | 28.36 | 10.10 | 52 | 233395 | 3950 | 63251625 |
Metastases to liver | 28.36 | 10.10 | 27 | 233420 | 23612 | 63231963 |
Clear cell renal cell carcinoma | 28.29 | 10.10 | 31 | 233416 | 1454 | 63254121 |
Balance disorder | 28.17 | 10.10 | 188 | 233259 | 84234 | 63171341 |
Photophobia | 28.12 | 10.10 | 134 | 233313 | 17501 | 63238074 |
Short stature | 28.06 | 10.10 | 22 | 233425 | 668 | 63254907 |
Acute myeloid leukaemia | 27.99 | 10.10 | 14 | 233433 | 17133 | 63238442 |
Oesophageal spasm | 27.95 | 10.10 | 45 | 233402 | 3078 | 63252497 |
Systemic lupus erythematosus | 27.89 | 10.10 | 571 | 232876 | 208347 | 63047228 |
Sacroiliitis | 27.88 | 10.10 | 46 | 233401 | 3211 | 63252364 |
Granuloma skin | 27.77 | 10.10 | 81 | 233366 | 8356 | 63247219 |
Clostridium difficile colitis | 27.73 | 10.10 | 21 | 233426 | 20548 | 63235027 |
Allergy to chemicals | 27.45 | 10.10 | 44 | 233403 | 2998 | 63252577 |
Drug eruption | 27.29 | 10.10 | 190 | 233257 | 28504 | 63227071 |
Tooth disorder | 27.11 | 10.10 | 187 | 233260 | 27970 | 63227605 |
Device related infection | 26.60 | 10.10 | 28 | 233419 | 23364 | 63232211 |
Breast cancer stage III | 26.21 | 10.10 | 91 | 233356 | 10295 | 63245280 |
Drug reaction with eosinophilia and systemic symptoms | 26.20 | 10.10 | 53 | 233394 | 33783 | 63221792 |
Urosepsis | 26.16 | 10.10 | 18 | 233429 | 18506 | 63237069 |
Urinary tract infection | 26.13 | 10.10 | 757 | 232690 | 263927 | 62991648 |
Hypokalaemia | 25.94 | 10.10 | 250 | 233197 | 103554 | 63152021 |
Haematoma | 25.74 | 10.10 | 56 | 233391 | 34764 | 63220811 |
Hallucination, visual | 25.64 | 10.10 | 20 | 233427 | 19278 | 63236297 |
Immunodeficiency | 25.43 | 10.10 | 144 | 233303 | 20110 | 63235465 |
Biliary dyskinesia | 25.35 | 10.10 | 40 | 233407 | 2689 | 63252886 |
Blood pressure measurement | 25.21 | 10.10 | 15 | 233432 | 286 | 63255289 |
Back pain | 25.15 | 10.10 | 1200 | 232247 | 262945 | 62992630 |
Full blood count abnormal | 25.14 | 10.10 | 49 | 233398 | 31668 | 63223907 |
Intestinal obstruction | 25.14 | 10.10 | 47 | 233400 | 30852 | 63224723 |
Hip arthroplasty | 25.12 | 10.10 | 277 | 233170 | 47369 | 63208206 |
No adverse event | 24.87 | 10.10 | 74 | 233373 | 41331 | 63214244 |
Quality of life decreased | 24.76 | 10.10 | 80 | 233367 | 8723 | 63246852 |
Panniculitis | 24.72 | 10.10 | 95 | 233352 | 11290 | 63244285 |
Hepatocellular injury | 24.70 | 10.10 | 39 | 233408 | 27342 | 63228233 |
Antinuclear antibody positive | 24.62 | 10.10 | 75 | 233372 | 7924 | 63247651 |
Rales | 24.58 | 10.10 | 8 | 233439 | 12689 | 63242886 |
Adverse reaction | 24.55 | 10.10 | 88 | 233359 | 10115 | 63245460 |
Skin ulcer | 24.44 | 10.10 | 254 | 233193 | 42791 | 63212784 |
Neuroleptic malignant syndrome | 24.41 | 10.10 | 7 | 233440 | 12049 | 63243526 |
Myofascial pain syndrome | 24.39 | 10.10 | 36 | 233411 | 2282 | 63253293 |
Joint injury | 24.23 | 10.10 | 189 | 233258 | 29383 | 63226192 |
Gallbladder injury | 24.20 | 10.10 | 28 | 233419 | 1395 | 63254180 |
Bone density increased | 24.20 | 10.10 | 21 | 233426 | 737 | 63254838 |
Malaise | 24.12 | 10.10 | 1808 | 231639 | 414146 | 62841429 |
Osteoarthritis | 24.02 | 10.10 | 488 | 232959 | 94855 | 63160720 |
Renal mass | 23.98 | 10.10 | 36 | 233411 | 2317 | 63253258 |
Hepatotoxicity | 23.88 | 10.10 | 64 | 233383 | 36977 | 63218598 |
Anosmia | 23.68 | 10.10 | 67 | 233380 | 6793 | 63248782 |
Upper gastrointestinal haemorrhage | 23.65 | 10.10 | 134 | 233313 | 18718 | 63236857 |
Oesophageal pain | 23.64 | 10.10 | 46 | 233401 | 3655 | 63251920 |
Night sweats | 23.58 | 10.10 | 279 | 233168 | 48535 | 63207040 |
Dysphagia | 23.58 | 10.10 | 210 | 233237 | 88375 | 63167200 |
Cerebral infarction | 23.54 | 10.10 | 32 | 233415 | 23861 | 63231714 |
Spinal fusion surgery | 23.51 | 10.10 | 59 | 233388 | 5569 | 63250006 |
Cardio-respiratory arrest | 23.44 | 10.10 | 127 | 233320 | 59832 | 63195743 |
C-reactive protein | 23.43 | 10.10 | 54 | 233393 | 4828 | 63250747 |
Cardiogenic shock | 23.30 | 10.10 | 19 | 233428 | 17913 | 63237662 |
Blood alkaline phosphatase increased | 22.89 | 10.10 | 81 | 233366 | 42886 | 63212689 |
Bone lesion | 22.86 | 10.10 | 60 | 233387 | 5821 | 63249754 |
Body temperature decreased | 22.64 | 10.10 | 140 | 233307 | 20179 | 63235396 |
Transfusion | 22.56 | 10.10 | 14 | 233433 | 15203 | 63240372 |
Aorta hypoplasia | 22.54 | 10.10 | 11 | 233436 | 138 | 63255437 |
Pericardial effusion | 22.50 | 10.10 | 48 | 233399 | 30010 | 63225565 |
Left ventricular dysfunction | 22.43 | 10.10 | 8 | 233439 | 11980 | 63243595 |
Sensitivity to weather change | 22.41 | 10.10 | 68 | 233379 | 7169 | 63248406 |
Diabetes mellitus inadequate control | 22.31 | 10.10 | 14 | 233433 | 15112 | 63240463 |
Premature labour | 22.30 | 10.10 | 9 | 233438 | 12495 | 63243080 |
Sciatica | 22.14 | 10.10 | 208 | 233239 | 34116 | 63221459 |
Musculoskeletal discomfort | 22.07 | 10.10 | 127 | 233320 | 17840 | 63237735 |
Cholestasis | 22.03 | 10.10 | 47 | 233400 | 29387 | 63226188 |
Oesophageal ulcer | 21.92 | 10.10 | 50 | 233397 | 4440 | 63251135 |
Synovial disorder | 21.87 | 10.10 | 32 | 233415 | 2013 | 63253562 |
Prescribed underdose | 21.76 | 10.10 | 185 | 233262 | 29504 | 63226071 |
Blood calcium decreased | 21.73 | 10.10 | 40 | 233407 | 26411 | 63229164 |
Crepitations | 21.66 | 10.10 | 72 | 233375 | 7968 | 63247607 |
Swollen joint count increased | 21.54 | 10.10 | 215 | 233232 | 35839 | 63219736 |
Depressed level of consciousness | 21.34 | 10.10 | 137 | 233310 | 61941 | 63193634 |
Facial pain | 21.22 | 10.10 | 86 | 233361 | 10475 | 63245100 |
Ileus | 21.21 | 10.10 | 14 | 233433 | 14711 | 63240864 |
Metastases to bone | 20.86 | 10.10 | 28 | 233419 | 20991 | 63234584 |
Acute respiratory distress syndrome | 20.78 | 10.10 | 34 | 233413 | 23500 | 63232075 |
Medication overuse headache | 20.61 | 10.10 | 20 | 233427 | 812 | 63254763 |
Bacteraemia | 20.60 | 10.10 | 20 | 233427 | 17328 | 63238247 |
Blood sodium decreased | 20.53 | 10.10 | 36 | 233411 | 24216 | 63231359 |
Bronchospasm | 20.42 | 10.10 | 20 | 233427 | 17260 | 63238315 |
Blood cholesterol increased | 20.39 | 10.10 | 471 | 232976 | 93561 | 63162014 |
Dyspepsia | 20.37 | 10.10 | 506 | 232941 | 101690 | 63153885 |
Goitre | 20.36 | 10.10 | 58 | 233389 | 5903 | 63249672 |
Joint ankylosis | 20.21 | 10.10 | 22 | 233425 | 1024 | 63254551 |
Lower respiratory tract infection | 20.18 | 10.10 | 633 | 232814 | 131674 | 63123901 |
Flank pain | 20.17 | 10.10 | 116 | 233331 | 16294 | 63239281 |
Skin necrosis | 20.11 | 10.10 | 103 | 233344 | 13847 | 63241728 |
Red blood cell count decreased | 19.94 | 10.10 | 233 | 233214 | 40412 | 63215163 |
Bronchiectasis | 19.88 | 10.10 | 18 | 233429 | 16124 | 63239451 |
Aspergillus infection | 19.88 | 10.10 | 3 | 233444 | 8090 | 63247485 |
Collagen-vascular disease | 19.81 | 10.10 | 9 | 233438 | 95 | 63255480 |
Caesarean section | 19.80 | 10.10 | 20 | 233427 | 17012 | 63238563 |
Intentional product use issue | 19.80 | 10.10 | 613 | 232834 | 127279 | 63128296 |
Pharyngeal swelling | 19.67 | 10.10 | 60 | 233387 | 6344 | 63249231 |
Blood potassium increased | 19.62 | 10.10 | 23 | 233424 | 18286 | 63237289 |
Endocarditis fibroplastica | 19.60 | 10.10 | 5 | 233442 | 5 | 63255570 |
Type 2 diabetes mellitus | 19.58 | 10.10 | 337 | 233110 | 63531 | 63192044 |
Device ineffective | 19.57 | 10.10 | 12 | 233435 | 242 | 63255333 |
Cyanosis | 19.56 | 10.10 | 20 | 233427 | 16915 | 63238660 |
Adenoiditis | 19.53 | 10.10 | 7 | 233440 | 37 | 63255538 |
Polyneuropathy | 19.53 | 10.10 | 15 | 233432 | 14574 | 63241001 |
Therapy interrupted | 19.50 | 10.10 | 58 | 233389 | 32397 | 63223178 |
Therapy cessation | 19.35 | 10.10 | 53 | 233394 | 30404 | 63225171 |
Rash pruritic | 19.23 | 10.10 | 318 | 233129 | 59481 | 63196094 |
Hodgkin's disease | 19.21 | 10.10 | 19 | 233428 | 790 | 63254785 |
Loss of personal independence in daily activities | 19.18 | 10.10 | 481 | 232966 | 96809 | 63158766 |
Gastroenteritis viral | 19.16 | 10.10 | 151 | 233296 | 23549 | 63232026 |
Blood bilirubin increased | 19.13 | 10.10 | 71 | 233376 | 37069 | 63218506 |
Pancreatitis | 19.12 | 10.10 | 104 | 233343 | 48951 | 63206624 |
Epistaxis | 19.09 | 10.10 | 173 | 233274 | 72552 | 63183023 |
Circulatory collapse | 19.08 | 10.10 | 32 | 233415 | 21906 | 63233669 |
Allodynia | 19.01 | 10.10 | 19 | 233428 | 800 | 63254775 |
Arrhythmia | 18.94 | 10.10 | 74 | 233373 | 38066 | 63217509 |
Heart rate | 18.91 | 10.10 | 8 | 233439 | 70 | 63255505 |
Paradoxical drug reaction | 18.91 | 10.10 | 45 | 233402 | 4107 | 63251468 |
Jejunal ulcer | 18.87 | 10.10 | 9 | 233438 | 107 | 63255468 |
Cardiotoxicity | 18.83 | 10.10 | 4 | 233443 | 8434 | 63247141 |
Hepatic encephalopathy | 18.73 | 10.10 | 9 | 233438 | 11273 | 63244302 |
Hypoalbuminaemia | 18.73 | 10.10 | 10 | 233437 | 11795 | 63243780 |
Limb operation | 18.70 | 10.10 | 44 | 233403 | 3987 | 63251588 |
Diabetic ketoacidosis | 18.69 | 10.10 | 29 | 233418 | 20476 | 63235099 |
Tumour lysis syndrome | 18.61 | 10.10 | 5 | 233442 | 8985 | 63246590 |
Skin papilloma | 18.61 | 10.10 | 50 | 233397 | 4919 | 63250656 |
Feeling abnormal | 18.61 | 10.10 | 694 | 232753 | 147698 | 63107877 |
Hepatic adenoma | 18.59 | 10.10 | 13 | 233434 | 330 | 63255245 |
Atelectasis | 18.55 | 10.10 | 139 | 233308 | 21344 | 63234231 |
Metastases to lung | 18.53 | 10.10 | 12 | 233435 | 12738 | 63242837 |
Chronic spontaneous urticaria | 18.40 | 10.10 | 22 | 233425 | 1135 | 63254440 |
Wheezing | 18.37 | 10.10 | 471 | 232976 | 95124 | 63160451 |
Joint noise | 18.30 | 10.10 | 46 | 233401 | 4346 | 63251229 |
Fall | 18.24 | 10.10 | 1220 | 232227 | 391114 | 62864461 |
Obstructive airways disorder | 18.19 | 10.10 | 30 | 233417 | 20669 | 63234906 |
Eosinophilia | 18.17 | 10.10 | 35 | 233412 | 22721 | 63232854 |
Cytopenia | 18.15 | 10.10 | 10 | 233437 | 11591 | 63243984 |
Blood potassium decreased | 18.14 | 10.10 | 86 | 233361 | 41940 | 63213635 |
Drug level increased | 18.13 | 10.10 | 35 | 233412 | 22701 | 63232874 |
Tendon rupture | 18.09 | 10.10 | 69 | 233378 | 8170 | 63247405 |
Rheumatic fever | 18.08 | 10.10 | 240 | 233207 | 42871 | 63212704 |
Finger deformity | 17.96 | 10.10 | 66 | 233381 | 7679 | 63247896 |
Lactic acidosis | 17.94 | 10.10 | 76 | 233371 | 38211 | 63217364 |
Anti-transglutaminase antibody | 17.93 | 10.10 | 5 | 233442 | 9 | 63255566 |
Cardiomyopathy | 17.89 | 10.10 | 23 | 233424 | 17561 | 63238014 |
Breath sounds abnormal | 17.85 | 10.10 | 9 | 233438 | 10964 | 63244611 |
Parkinsonism | 17.84 | 10.10 | 8 | 233439 | 10431 | 63245144 |
Kidney infection | 17.83 | 10.10 | 146 | 233301 | 23030 | 63232545 |
Human anti-human antibody test | 17.83 | 10.10 | 14 | 233433 | 426 | 63255149 |
Spondyloarthropathy | 17.75 | 10.10 | 19 | 233428 | 868 | 63254707 |
Malnutrition | 17.74 | 10.10 | 18 | 233429 | 15280 | 63240295 |
Laboratory test abnormal | 17.72 | 10.10 | 46 | 233401 | 26866 | 63228709 |
Eosinophil count increased | 17.72 | 10.10 | 9 | 233438 | 10919 | 63244656 |
Haemorrhage intracranial | 17.71 | 10.10 | 14 | 233433 | 13405 | 63242170 |
Subdural haematoma | 17.62 | 10.10 | 16 | 233431 | 14312 | 63241263 |
Aspirin-exacerbated respiratory disease | 17.60 | 10.10 | 19 | 233428 | 876 | 63254699 |
Lymphopenia | 17.60 | 10.10 | 25 | 233422 | 18302 | 63237273 |
Pleural effusion | 17.60 | 10.10 | 239 | 233208 | 92971 | 63162604 |
Bronchopulmonary aspergillosis | 17.51 | 10.10 | 5 | 233442 | 8630 | 63246945 |
Nerve compression | 17.47 | 10.10 | 73 | 233374 | 9014 | 63246561 |
Endometriosis | 17.44 | 10.10 | 51 | 233396 | 5269 | 63250306 |
Pulmonary oedema | 17.41 | 10.10 | 124 | 233323 | 54749 | 63200826 |
Blood pressure diastolic increased | 17.39 | 10.10 | 78 | 233369 | 9932 | 63245643 |
Hepatic cirrhosis | 17.29 | 10.10 | 41 | 233406 | 24693 | 63230882 |
COVID-19 | 17.28 | 10.10 | 302 | 233145 | 112801 | 63142774 |
Metastases to fallopian tube | 17.20 | 10.10 | 7 | 233440 | 55 | 63255520 |
Glossodynia | 17.04 | 10.10 | 514 | 232933 | 178362 | 63077213 |
Glomerulonephritis minimal lesion | 17.02 | 10.10 | 11 | 233436 | 244 | 63255331 |
Sinus bradycardia | 17.02 | 10.10 | 17 | 233430 | 14534 | 63241041 |
Enterocolitis | 16.99 | 10.10 | 4 | 233443 | 7854 | 63247721 |
Dyspnoea exertional | 16.91 | 10.10 | 141 | 233306 | 60161 | 63195414 |
Radiation associated pain | 16.86 | 10.10 | 8 | 233439 | 94 | 63255481 |
Gait disturbance | 16.75 | 10.10 | 829 | 232618 | 182349 | 63073226 |
Ischaemic stroke | 16.75 | 10.10 | 25 | 233422 | 17932 | 63237643 |
Blood urea increased | 16.68 | 10.10 | 46 | 233401 | 26333 | 63229242 |
Deformity | 16.65 | 10.10 | 86 | 233361 | 11598 | 63243977 |
Sputum discoloured | 16.59 | 10.10 | 110 | 233337 | 16237 | 63239338 |
Oral candidiasis | 16.57 | 10.10 | 37 | 233410 | 22761 | 63232814 |
Adrenergic syndrome | 16.55 | 10.10 | 6 | 233441 | 33 | 63255542 |
Anaphylactic reaction | 16.54 | 10.10 | 338 | 233109 | 65762 | 63189813 |
Schizophrenia | 16.43 | 10.10 | 8 | 233439 | 9944 | 63245631 |
Blood albumin decreased | 16.42 | 10.10 | 18 | 233429 | 14748 | 63240827 |
Amblyopia | 16.41 | 10.10 | 11 | 233436 | 260 | 63255315 |
Aggression | 16.38 | 10.10 | 39 | 233408 | 23459 | 63232116 |
Unevaluable event | 16.36 | 10.10 | 116 | 233331 | 51270 | 63204305 |
Duodenal ulcer | 16.25 | 10.10 | 64 | 233383 | 7692 | 63247883 |
HLA marker study positive | 16.25 | 10.10 | 10 | 233437 | 203 | 63255372 |
Cushingoid | 16.18 | 10.10 | 68 | 233379 | 8417 | 63247158 |
Ventricular fibrillation | 16.15 | 10.10 | 12 | 233435 | 11855 | 63243720 |
Eye pain | 16.13 | 10.10 | 193 | 233254 | 33661 | 63221914 |
Breast cancer stage I | 15.93 | 10.10 | 3 | 233444 | 6886 | 63248689 |
Unresponsive to stimuli | 15.92 | 10.10 | 67 | 233380 | 33749 | 63221826 |
Staphylococcal infection | 15.79 | 10.10 | 88 | 233359 | 41168 | 63214407 |
Libido increased | 15.78 | 10.10 | 22 | 233425 | 1323 | 63254252 |
Gallbladder cholesterolosis | 15.66 | 10.10 | 17 | 233430 | 789 | 63254786 |
Blood lactate dehydrogenase increased | 15.62 | 10.10 | 39 | 233408 | 23077 | 63232498 |
Pre-eclampsia | 15.61 | 10.10 | 7 | 233440 | 9126 | 63246449 |
Abdominal pain | 15.57 | 10.10 | 1267 | 232180 | 292189 | 62963386 |
Complication associated with device | 15.49 | 10.10 | 24 | 233423 | 16954 | 63238621 |
Anomaly of external ear congenital | 15.48 | 10.10 | 9 | 233438 | 164 | 63255411 |
Status epilepticus | 15.42 | 10.10 | 20 | 233427 | 15213 | 63240362 |
Mental status changes | 15.41 | 10.10 | 84 | 233363 | 39515 | 63216060 |
Pemphigoid | 15.37 | 10.10 | 4 | 233443 | 7340 | 63248235 |
Pneumocystis jirovecii pneumonia | 15.34 | 10.10 | 24 | 233423 | 16890 | 63238685 |
Vascular device infection | 15.27 | 10.10 | 4 | 233443 | 7308 | 63248267 |
Nail dystrophy | 15.24 | 10.10 | 19 | 233428 | 1024 | 63254551 |
Accidental overdose | 15.23 | 10.10 | 40 | 233407 | 23269 | 63232306 |
Lip oedema | 15.22 | 10.10 | 40 | 233407 | 3884 | 63251691 |
IIIrd nerve injury | 15.21 | 10.10 | 4 | 233443 | 5 | 63255570 |
Nail psoriasis | 15.12 | 10.10 | 15 | 233432 | 626 | 63254949 |
Fixed eruption | 15.12 | 10.10 | 20 | 233427 | 1144 | 63254431 |
Skin fissures | 14.99 | 10.10 | 82 | 233365 | 11306 | 63244269 |
Sudden death | 14.96 | 10.10 | 10 | 233437 | 10439 | 63245136 |
Depression | 14.93 | 10.10 | 874 | 232573 | 195618 | 63059957 |
Clostridium difficile infection | 14.89 | 10.10 | 58 | 233389 | 29864 | 63225711 |
Normal newborn | 14.88 | 10.10 | 6 | 233441 | 8335 | 63247240 |
Adverse drug reaction | 14.80 | 10.10 | 391 | 233056 | 79323 | 63176252 |
Hypothyroidism | 14.69 | 10.10 | 94 | 233353 | 42538 | 63213037 |
Fine motor skill dysfunction | 14.63 | 10.10 | 45 | 233402 | 4780 | 63250795 |
Product label confusion | 14.62 | 10.10 | 25 | 233422 | 1797 | 63253778 |
Spondylitis | 14.52 | 10.10 | 42 | 233405 | 4312 | 63251263 |
Blood pressure systolic increased | 14.49 | 10.10 | 250 | 233197 | 47147 | 63208428 |
Blood pressure decreased | 14.44 | 10.10 | 161 | 233286 | 64861 | 63190714 |
Vaginal stricture | 14.42 | 10.10 | 4 | 233443 | 7 | 63255568 |
Myopathy | 14.36 | 10.10 | 12 | 233435 | 11179 | 63244396 |
Tachypnoea | 14.36 | 10.10 | 26 | 233421 | 17276 | 63238299 |
Infusion site pain | 14.31 | 10.10 | 25 | 233422 | 16844 | 63238731 |
Blood pressure diastolic abnormal | 14.25 | 10.10 | 97 | 233350 | 14445 | 63241130 |
Vaginal infection | 14.14 | 10.10 | 60 | 233387 | 7458 | 63248117 |
Haematocrit decreased | 14.09 | 10.10 | 213 | 233234 | 39127 | 63216448 |
Costovertebral angle tenderness | 14.06 | 10.10 | 7 | 233440 | 92 | 63255483 |
Shock | 14.04 | 10.10 | 42 | 233405 | 23421 | 63232154 |
Gastric disorder | 14.03 | 10.10 | 204 | 233243 | 37165 | 63218410 |
Oliguria | 14.02 | 10.10 | 8 | 233439 | 9093 | 63246482 |
Injection site reaction | 13.90 | 10.10 | 297 | 233150 | 58227 | 63197348 |
Foetal death | 13.82 | 10.10 | 12 | 233435 | 10968 | 63244607 |
Road traffic accident | 13.77 | 10.10 | 200 | 233247 | 36432 | 63219143 |
Onychomadesis | 13.74 | 10.10 | 50 | 233397 | 5790 | 63249785 |
Faecaloma | 13.71 | 10.10 | 6 | 233441 | 7935 | 63247640 |
Pulmonary fibrosis | 13.66 | 10.10 | 214 | 233233 | 39595 | 63215980 |
Periorbital oedema | 13.65 | 10.10 | 49 | 233398 | 5635 | 63249940 |
Asphyxia | 13.65 | 10.10 | 3 | 233444 | 6178 | 63249397 |
Meningitis streptococcal | 13.61 | 10.10 | 8 | 233439 | 149 | 63255426 |
Red cell distribution width decreased | 13.60 | 10.10 | 26 | 233421 | 2039 | 63253536 |
Lupus-like syndrome | 13.59 | 10.10 | 22 | 233425 | 15273 | 63240302 |
Stress cardiomyopathy | 13.59 | 10.10 | 9 | 233438 | 9441 | 63246134 |
Acquired cystic kidney disease | 13.49 | 10.10 | 6 | 233441 | 60 | 63255515 |
Aspartate aminotransferase increased | 13.48 | 10.10 | 242 | 233205 | 90035 | 63165540 |
Genitourinary symptom | 13.32 | 10.10 | 6 | 233441 | 62 | 63255513 |
Cholesterosis | 13.32 | 10.10 | 12 | 233435 | 443 | 63255132 |
Supraventricular tachycardia | 13.19 | 10.10 | 20 | 233427 | 14251 | 63241324 |
Sleep disorder | 13.17 | 10.10 | 393 | 233054 | 81173 | 63174402 |
Limb asymmetry | 13.10 | 10.10 | 16 | 233431 | 844 | 63254731 |
Hypophagia | 13.10 | 10.10 | 174 | 233273 | 31085 | 63224490 |
Tooth hypoplasia | 13.07 | 10.10 | 6 | 233441 | 65 | 63255510 |
Hypovolaemia | 13.03 | 10.10 | 12 | 233435 | 10661 | 63244914 |
Anal abscess | 12.94 | 10.10 | 42 | 233405 | 4590 | 63250985 |
Muscle spasms | 12.92 | 10.10 | 700 | 232747 | 155450 | 63100125 |
Tendon disorder | 12.89 | 10.10 | 49 | 233398 | 5794 | 63249781 |
Therapeutic product effect variable | 12.88 | 10.10 | 19 | 233428 | 1204 | 63254371 |
Hostility | 12.86 | 10.10 | 24 | 233423 | 1848 | 63253727 |
Troponin increased | 12.81 | 10.10 | 11 | 233436 | 10110 | 63245465 |
Generalised tonic-clonic seizure | 12.74 | 10.10 | 59 | 233388 | 28957 | 63226618 |
Muscle twitching | 12.59 | 10.10 | 119 | 233328 | 19549 | 63236026 |
Spinal cord infection | 12.53 | 10.10 | 14 | 233433 | 671 | 63254904 |
Spleen congestion | 12.52 | 10.10 | 7 | 233440 | 118 | 63255457 |
Epstein-Barr virus infection | 12.51 | 10.10 | 7 | 233440 | 8043 | 63247532 |
Anxiety | 12.48 | 10.10 | 945 | 232502 | 216596 | 63038979 |
Lymphocyte count decreased | 12.43 | 10.10 | 63 | 233384 | 30194 | 63225381 |
Cardiac disorder | 12.43 | 10.10 | 123 | 233324 | 50693 | 63204882 |
Dialysis | 12.40 | 10.10 | 12 | 233435 | 10415 | 63245160 |
Blood pressure systolic abnormal | 12.36 | 10.10 | 88 | 233359 | 13298 | 63242277 |
Pneumonia bacterial | 12.33 | 10.10 | 10 | 233437 | 9455 | 63246120 |
Hemiparesis | 12.33 | 10.10 | 44 | 233403 | 23238 | 63232337 |
Post-traumatic neck syndrome | 12.31 | 10.10 | 25 | 233422 | 2049 | 63253526 |
Alanine aminotransferase increased | 12.28 | 10.10 | 289 | 233158 | 103481 | 63152094 |
Lipase increased | 12.24 | 10.10 | 11 | 233436 | 9889 | 63245686 |
Labelled drug-drug interaction medication error | 12.17 | 10.10 | 19 | 233428 | 13380 | 63242195 |
Myoclonus | 12.16 | 10.10 | 25 | 233422 | 15843 | 63239732 |
Pseudomonas infection | 12.11 | 10.10 | 14 | 233433 | 11199 | 63244376 |
Left ventricular failure | 12.09 | 10.10 | 3 | 233444 | 5684 | 63249891 |
Single umbilical artery | 12.07 | 10.10 | 9 | 233438 | 253 | 63255322 |
Pancreatitis acute | 12.07 | 10.10 | 55 | 233392 | 27111 | 63228464 |
Rash | 11.93 | 10.10 | 2287 | 231160 | 558584 | 62696991 |
Spinal pain | 11.91 | 10.10 | 86 | 233361 | 13053 | 63242522 |
Lipidosis | 11.90 | 10.10 | 5 | 233442 | 43 | 63255532 |
Muscular weakness | 11.87 | 10.10 | 557 | 232890 | 121796 | 63133779 |
Head injury | 11.86 | 10.10 | 56 | 233391 | 27340 | 63228235 |
Oropharyngeal oedema | 11.82 | 10.10 | 10 | 233437 | 339 | 63255236 |
Accidental exposure to product by child | 11.80 | 10.10 | 18 | 233429 | 1175 | 63254400 |
Hypertensive crisis | 11.79 | 10.10 | 24 | 233423 | 15262 | 63240313 |
Wrong product procured | 11.76 | 10.10 | 3 | 233444 | 3 | 63255572 |
Colostomy infection | 11.76 | 10.10 | 3 | 233444 | 3 | 63255572 |
Headache | 11.75 | 10.10 | 2565 | 230882 | 630676 | 62624899 |
Mania | 11.75 | 10.10 | 17 | 233430 | 12350 | 63243225 |
Restlessness | 11.72 | 10.10 | 62 | 233385 | 29391 | 63226184 |
Sedation | 11.69 | 10.10 | 89 | 233358 | 38720 | 63216855 |
Atrioventricular block complete | 11.68 | 10.10 | 8 | 233439 | 8243 | 63247332 |
Metastases to central nervous system | 11.51 | 10.10 | 19 | 233428 | 13086 | 63242489 |
Colitis ulcerative | 11.49 | 10.10 | 53 | 233394 | 26038 | 63229537 |
Wound | 11.47 | 10.10 | 487 | 232960 | 162776 | 63092799 |
Toxicity to various agents | 11.44 | 10.10 | 769 | 232678 | 246481 | 63009094 |
Vaginal abscess | 11.39 | 10.10 | 11 | 233436 | 444 | 63255131 |
Hyperthyroidism | 11.34 | 10.10 | 23 | 233424 | 14650 | 63240925 |
Staphylococcal sepsis | 11.34 | 10.10 | 8 | 233439 | 8120 | 63247455 |
Pregnancy | 11.32 | 10.10 | 84 | 233363 | 36752 | 63218823 |
Blood pressure fluctuation | 11.31 | 10.10 | 236 | 233211 | 46081 | 63209494 |
Oesophageal atresia | 11.30 | 10.10 | 12 | 233435 | 543 | 63255032 |
Aphasia | 11.25 | 10.10 | 73 | 233374 | 32927 | 63222648 |
Hepatic enzyme abnormal | 11.25 | 10.10 | 50 | 233397 | 6342 | 63249233 |
Polymenorrhagia | 11.24 | 10.10 | 5 | 233442 | 50 | 63255525 |
Aspiration | 11.24 | 10.10 | 14 | 233433 | 10837 | 63244738 |
Frequent bowel movements | 11.22 | 10.10 | 45 | 233402 | 22977 | 63232598 |
COVID-19 pneumonia | 11.22 | 10.10 | 22 | 233425 | 14187 | 63241388 |
Glaucoma | 11.20 | 10.10 | 34 | 233413 | 18871 | 63236704 |
Lung disorder | 11.16 | 10.10 | 304 | 233143 | 61957 | 63193618 |
Torsade de pointes | 11.13 | 10.10 | 20 | 233427 | 13331 | 63242244 |
Parakeratosis | 11.13 | 10.10 | 9 | 233438 | 286 | 63255289 |
Lower limb fracture | 11.07 | 10.10 | 137 | 233310 | 24084 | 63231491 |
Septic arthritis staphylococcal | 11.03 | 10.10 | 11 | 233436 | 462 | 63255113 |
Lip and/or oral cavity cancer | 11.01 | 10.10 | 15 | 233432 | 883 | 63254692 |
Dementia | 10.99 | 10.10 | 34 | 233413 | 18760 | 63236815 |
Basal cell carcinoma | 10.99 | 10.10 | 154 | 233293 | 27837 | 63227738 |
Pseudodementia | 10.96 | 10.10 | 6 | 233441 | 97 | 63255478 |
Bradyphrenia | 10.95 | 10.10 | 6 | 233441 | 6974 | 63248601 |
Proteinuria | 10.94 | 10.10 | 35 | 233412 | 19110 | 63236465 |
Transaminases increased | 10.89 | 10.10 | 69 | 233378 | 31298 | 63224277 |
Sternal fracture | 10.89 | 10.10 | 25 | 233422 | 2229 | 63253346 |
Gastrointestinal submucosal tumour | 10.88 | 10.10 | 4 | 233443 | 23 | 63255552 |
Inflammatory pain | 10.83 | 10.10 | 15 | 233432 | 897 | 63254678 |
Maternal drugs affecting foetus | 10.70 | 10.10 | 3 | 233444 | 5239 | 63250336 |
Compartment syndrome | 10.67 | 10.10 | 25 | 233422 | 2259 | 63253316 |
Infective pulmonary exacerbation of cystic fibrosis | 10.66 | 10.10 | 10 | 233437 | 8807 | 63246768 |
Metabolic encephalopathy | 10.66 | 10.10 | 4 | 233443 | 5805 | 63249770 |
Brain natriuretic peptide increased | 10.61 | 10.10 | 3 | 233444 | 5210 | 63250365 |
Trigger finger | 10.59 | 10.10 | 38 | 233409 | 4370 | 63251205 |
Poor quality sleep | 10.55 | 10.10 | 116 | 233331 | 19819 | 63235756 |
Blood glucose increased | 10.55 | 10.10 | 231 | 233216 | 83525 | 63172050 |
Sleep disorder due to general medical condition, insomnia type | 10.55 | 10.10 | 132 | 233315 | 52085 | 63203490 |
Generalised oedema | 10.45 | 10.10 | 27 | 233420 | 15791 | 63239784 |
Spinal osteoarthritis | 10.39 | 10.10 | 98 | 233349 | 16088 | 63239487 |
Congenital choroid plexus cyst | 10.37 | 10.10 | 9 | 233438 | 316 | 63255259 |
Plantar fasciitis | 10.34 | 10.10 | 34 | 233413 | 3741 | 63251834 |
Progressive multifocal leukoencephalopathy | 10.31 | 10.10 | 20 | 233427 | 12951 | 63242624 |
Food aversion | 10.30 | 10.10 | 14 | 233433 | 822 | 63254753 |
Haemorrhage | 10.28 | 10.10 | 160 | 233287 | 60862 | 63194713 |
Tremor | 10.24 | 10.10 | 390 | 233057 | 131849 | 63123726 |
Failure of child resistant product closure | 10.22 | 10.10 | 4 | 233443 | 28 | 63255547 |
Retinitis | 10.20 | 10.10 | 5 | 233442 | 6191 | 63249384 |
Diffuse large B-cell lymphoma | 10.20 | 10.10 | 6 | 233441 | 6706 | 63248869 |
Dysmenorrhoea | 10.19 | 10.10 | 35 | 233412 | 3938 | 63251637 |
Cytomegalovirus viraemia | 10.18 | 10.10 | 4 | 233443 | 5645 | 63249930 |
Cardiac failure acute | 10.17 | 10.10 | 12 | 233435 | 9511 | 63246064 |
Failure to thrive | 10.16 | 10.10 | 7 | 233440 | 7191 | 63248384 |
Musculoskeletal deformity | 10.15 | 10.10 | 22 | 233425 | 1887 | 63253688 |
Toxic skin eruption | 10.13 | 10.10 | 20 | 233427 | 12865 | 63242710 |
Altered state of consciousness | 10.10 | 10.10 | 53 | 233394 | 25177 | 63230398 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Ankylosing spondylitis | 379.06 | 10.85 | 206 | 79775 | 5398 | 34871552 |
Gastric haemorrhage | 249.99 | 10.85 | 199 | 79782 | 10062 | 34866888 |
Arthralgia | 242.98 | 10.85 | 897 | 79084 | 169144 | 34707806 |
Psoriatic arthropathy | 231.22 | 10.85 | 255 | 79726 | 19543 | 34857407 |
Joint swelling | 208.57 | 10.85 | 438 | 79543 | 59452 | 34817498 |
Musculoskeletal stiffness | 203.23 | 10.85 | 375 | 79606 | 46305 | 34830645 |
Duodenal ulcer | 199.11 | 10.85 | 175 | 79806 | 10157 | 34866793 |
Pain | 182.57 | 10.85 | 937 | 79044 | 203738 | 34673212 |
Psoriasis | 143.45 | 10.85 | 291 | 79690 | 38521 | 34838429 |
Lip swelling | 131.72 | 10.85 | 173 | 79808 | 15907 | 34861043 |
Death | 130.38 | 10.85 | 471 | 79510 | 397578 | 34479372 |
Upper gastrointestinal haemorrhage | 129.07 | 10.85 | 219 | 79762 | 25299 | 34851651 |
Cardiospasm | 129.03 | 10.85 | 66 | 79915 | 1522 | 34875428 |
Neutropenia | 123.89 | 10.85 | 106 | 79875 | 156672 | 34720278 |
Palmoplantar keratoderma | 113.52 | 10.85 | 65 | 79916 | 1888 | 34875062 |
Pruritus genital | 111.38 | 10.85 | 67 | 79914 | 2137 | 34874813 |
Acne cystic | 109.36 | 10.85 | 42 | 79939 | 472 | 34876478 |
Sleep terror | 105.73 | 10.85 | 66 | 79915 | 2252 | 34874698 |
Febrile neutropenia | 103.91 | 10.85 | 96 | 79885 | 136753 | 34740197 |
Gastrointestinal haemorrhage | 103.61 | 10.85 | 439 | 79542 | 88038 | 34788912 |
Off label use | 99.12 | 10.85 | 560 | 79421 | 418964 | 34457986 |
Melaena | 98.70 | 10.85 | 237 | 79744 | 35143 | 34841807 |
Tension headache | 98.57 | 10.85 | 70 | 79911 | 2972 | 34873978 |
Angioedema | 98.56 | 10.85 | 245 | 79736 | 37129 | 34839821 |
Rheumatoid arthritis | 92.88 | 10.85 | 243 | 79738 | 37995 | 34838955 |
Carotid artery occlusion | 92.13 | 10.85 | 73 | 79908 | 3664 | 34873286 |
Migraine | 91.03 | 10.85 | 152 | 79829 | 17326 | 34859624 |
Anosmia | 89.46 | 10.85 | 74 | 79907 | 3950 | 34873000 |
Facial pain | 88.42 | 10.85 | 71 | 79910 | 3633 | 34873317 |
Immunisation | 88.19 | 10.85 | 45 | 79936 | 1032 | 34875918 |
Gastric ulcer | 88.13 | 10.85 | 141 | 79840 | 15509 | 34861441 |
Atrial tachycardia | 87.29 | 10.85 | 70 | 79911 | 3575 | 34873375 |
Congenital hiatus hernia | 86.22 | 10.85 | 41 | 79940 | 803 | 34876147 |
Pancytopenia | 76.74 | 10.85 | 63 | 79918 | 95094 | 34781856 |
Eye pruritus | 76.45 | 10.85 | 90 | 79891 | 7399 | 34869551 |
Arthritis | 75.91 | 10.85 | 199 | 79782 | 31147 | 34845803 |
Duodenal ulcer haemorrhage | 75.46 | 10.85 | 74 | 79907 | 4939 | 34872011 |
Thrombocytopenia | 74.91 | 10.85 | 153 | 79828 | 156094 | 34720856 |
Pain in extremity | 73.83 | 10.85 | 519 | 79462 | 125994 | 34750956 |
Back pain | 73.65 | 10.85 | 504 | 79477 | 121285 | 34755665 |
Sepsis | 71.74 | 10.85 | 173 | 79808 | 166388 | 34710562 |
Transient ischaemic attack | 71.72 | 10.85 | 180 | 79801 | 27433 | 34849517 |
Milk-alkali syndrome | 69.89 | 10.85 | 32 | 79949 | 573 | 34876377 |
Abdominal discomfort | 69.31 | 10.85 | 296 | 79685 | 59539 | 34817411 |
Sacroiliitis | 69.20 | 10.85 | 43 | 79938 | 1455 | 34875495 |
Peripheral swelling | 65.60 | 10.85 | 347 | 79634 | 76194 | 34800756 |
Pain of skin | 63.33 | 10.85 | 74 | 79907 | 6035 | 34870915 |
IgM nephropathy | 63.29 | 10.85 | 20 | 79961 | 118 | 34876832 |
Neck pain | 62.47 | 10.85 | 162 | 79819 | 25187 | 34851763 |
Cardiac failure | 62.40 | 10.85 | 70 | 79911 | 91178 | 34785772 |
Pneumonia | 61.38 | 10.85 | 533 | 79448 | 362094 | 34514856 |
Completed suicide | 60.36 | 10.85 | 408 | 79573 | 97760 | 34779190 |
Faeces discoloured | 60.30 | 10.85 | 116 | 79865 | 14762 | 34862188 |
Gastric ulcer haemorrhage | 57.98 | 10.85 | 67 | 79914 | 5399 | 34871551 |
Pericarditis | 57.62 | 10.85 | 99 | 79882 | 11546 | 34865404 |
Synovitis | 54.97 | 10.85 | 108 | 79873 | 13958 | 34862992 |
Joint injury | 54.90 | 10.85 | 85 | 79896 | 9088 | 34867862 |
Haematemesis | 53.44 | 10.85 | 162 | 79819 | 27549 | 34849401 |
Leukopenia | 52.70 | 10.85 | 40 | 79941 | 62816 | 34814134 |
Septic shock | 52.59 | 10.85 | 52 | 79929 | 71782 | 34805168 |
Atrial fibrillation | 50.42 | 10.85 | 130 | 79851 | 122263 | 34754687 |
Enthesopathy | 49.70 | 10.85 | 57 | 79924 | 4556 | 34872394 |
Peptic ulcer | 49.37 | 10.85 | 45 | 79936 | 2738 | 34874212 |
Muscle twitching | 48.93 | 10.85 | 86 | 79895 | 10212 | 34866738 |
Grip strength decreased | 46.25 | 10.85 | 46 | 79935 | 3123 | 34873827 |
Tinnitus | 44.95 | 10.85 | 124 | 79857 | 19994 | 34856956 |
Disability | 43.32 | 10.85 | 54 | 79927 | 4711 | 34872239 |
C-reactive protein abnormal | 43.03 | 10.85 | 74 | 79907 | 8636 | 34868314 |
Osteoarthritis | 42.96 | 10.85 | 124 | 79857 | 20518 | 34856432 |
Duodenal ulcer perforation | 42.65 | 10.85 | 33 | 79948 | 1599 | 34875351 |
Cytomegalovirus infection | 42.41 | 10.85 | 5 | 79976 | 26130 | 34850820 |
General physical health deterioration | 42.26 | 10.85 | 151 | 79830 | 128118 | 34748832 |
Insomnia | 41.42 | 10.85 | 391 | 79590 | 103516 | 34773434 |
Bradycardia | 39.47 | 10.85 | 70 | 79911 | 75348 | 34801602 |
Musculoskeletal discomfort | 37.85 | 10.85 | 67 | 79914 | 8001 | 34868949 |
Disease progression | 37.79 | 10.85 | 124 | 79857 | 107953 | 34768997 |
Abdominal pain upper | 37.47 | 10.85 | 286 | 79695 | 71204 | 34805746 |
Product used for unknown indication | 37.46 | 10.85 | 25 | 79956 | 958 | 34875992 |
Drug resistance | 37.38 | 10.85 | 7 | 79974 | 25920 | 34851030 |
Drug interaction | 37.27 | 10.85 | 334 | 79647 | 225612 | 34651338 |
Hypoglycaemia | 37.25 | 10.85 | 42 | 79939 | 54598 | 34822352 |
Muscle swelling | 36.97 | 10.85 | 18 | 79963 | 372 | 34876578 |
Vasculitis | 36.26 | 10.85 | 80 | 79901 | 11216 | 34865734 |
Anxiety | 35.65 | 10.85 | 366 | 79615 | 99062 | 34777888 |
Rash papular | 35.52 | 10.85 | 75 | 79906 | 10203 | 34866747 |
Ascites | 34.91 | 10.85 | 33 | 79948 | 46538 | 34830412 |
Withdrawal arrhythmia | 34.82 | 10.85 | 10 | 79971 | 40 | 34876910 |
Hyponatraemia | 34.67 | 10.85 | 87 | 79894 | 82604 | 34794346 |
Hospitalisation | 34.34 | 10.85 | 48 | 79933 | 56854 | 34820096 |
Product use in unapproved indication | 33.80 | 10.85 | 146 | 79835 | 117353 | 34759597 |
Arthropathy | 33.39 | 10.85 | 136 | 79845 | 26771 | 34850179 |
Hypokalaemia | 33.28 | 10.85 | 51 | 79930 | 58163 | 34818787 |
Gastrointestinal ulcer | 32.99 | 10.85 | 29 | 79952 | 1682 | 34875268 |
Malignant melanoma in situ | 32.75 | 10.85 | 29 | 79952 | 1699 | 34875251 |
Gastritis | 32.44 | 10.85 | 117 | 79864 | 21756 | 34855194 |
Musculoskeletal disorder | 32.36 | 10.85 | 54 | 79927 | 6150 | 34870800 |
Seronegative arthritis | 31.58 | 10.85 | 23 | 79958 | 1016 | 34875934 |
Gastritis erosive | 31.43 | 10.85 | 52 | 79929 | 5880 | 34871070 |
Discomfort | 31.29 | 10.85 | 105 | 79876 | 18833 | 34858117 |
Accidental exposure to product by child | 30.45 | 10.85 | 26 | 79955 | 1450 | 34875500 |
Diplopia | 30.18 | 10.85 | 96 | 79885 | 16747 | 34860203 |
Neutrophil count decreased | 29.96 | 10.85 | 44 | 79937 | 51060 | 34825890 |
Hyperhidrosis | 29.73 | 10.85 | 284 | 79697 | 75408 | 34801542 |
Platelet count decreased | 29.62 | 10.85 | 157 | 79824 | 119560 | 34757390 |
Renal papillary necrosis | 29.40 | 10.85 | 12 | 79969 | 160 | 34876790 |
Subarachnoid haemorrhage | 29.34 | 10.85 | 79 | 79902 | 12556 | 34864394 |
Drug hypersensitivity | 29.13 | 10.85 | 297 | 79684 | 80232 | 34796718 |
Spinal osteoarthritis | 28.83 | 10.85 | 58 | 79923 | 7625 | 34869325 |
Lymphocyte count abnormal | 28.67 | 10.85 | 23 | 79958 | 1175 | 34875775 |
Pseudoporphyria | 28.52 | 10.85 | 15 | 79966 | 367 | 34876583 |
Tendonitis | 28.51 | 10.85 | 64 | 79917 | 9076 | 34867874 |
Gastrointestinal fistula | 28.50 | 10.85 | 16 | 79965 | 447 | 34876503 |
White blood cell count decreased | 28.43 | 10.85 | 117 | 79864 | 95328 | 34781622 |
Headache | 28.35 | 10.85 | 629 | 79352 | 200006 | 34676944 |
Feeling abnormal | 28.27 | 10.85 | 244 | 79737 | 62991 | 34813959 |
Diverticulitis | 27.98 | 10.85 | 105 | 79876 | 19899 | 34857051 |
Fibromyalgia | 27.97 | 10.85 | 35 | 79946 | 3065 | 34873885 |
Visual impairment | 27.74 | 10.85 | 158 | 79823 | 35644 | 34841306 |
Loss of personal independence in daily activities | 27.43 | 10.85 | 149 | 79832 | 33030 | 34843920 |
Drug abuse | 27.36 | 10.85 | 125 | 79856 | 98971 | 34777979 |
Back disorder | 27.12 | 10.85 | 52 | 79929 | 6599 | 34870351 |
Anti-glomerular basement membrane disease | 27.10 | 10.85 | 8 | 79973 | 36 | 34876914 |
Dactylitis | 27.10 | 10.85 | 20 | 79961 | 902 | 34876048 |
Exposure to communicable disease | 27.00 | 10.85 | 11 | 79970 | 146 | 34876804 |
Therapeutic product effect incomplete | 26.92 | 10.85 | 203 | 79778 | 50338 | 34826612 |
Drug tolerance | 26.74 | 10.85 | 33 | 79948 | 2849 | 34874101 |
Spinal pain | 26.46 | 10.85 | 48 | 79933 | 5841 | 34871109 |
Nephrolithiasis | 26.29 | 10.85 | 138 | 79843 | 30195 | 34846755 |
Joint stiffness | 26.28 | 10.85 | 69 | 79912 | 10804 | 34866146 |
Palpitations | 26.24 | 10.85 | 169 | 79812 | 39817 | 34837133 |
Myelosuppression | 26.12 | 10.85 | 6 | 79975 | 19259 | 34857691 |
Urticaria | 25.98 | 10.85 | 237 | 79744 | 62140 | 34814810 |
Pyrexia | 25.87 | 10.85 | 573 | 79408 | 332440 | 34544510 |
Heart rate increased | 25.74 | 10.85 | 188 | 79793 | 46155 | 34830795 |
Joint effusion | 25.49 | 10.85 | 44 | 79937 | 5149 | 34871801 |
Uveitis | 24.90 | 10.85 | 54 | 79927 | 7481 | 34869469 |
Mycobacterium tuberculosis complex test positive | 24.54 | 10.85 | 22 | 79959 | 1310 | 34875640 |
Glomerulonephritis membranous | 24.52 | 10.85 | 21 | 79960 | 1176 | 34875774 |
Exostosis | 24.48 | 10.85 | 41 | 79940 | 4682 | 34872268 |
Respiratory failure | 24.35 | 10.85 | 147 | 79834 | 108425 | 34768525 |
Hepatic function abnormal | 24.28 | 10.85 | 40 | 79941 | 44323 | 34832627 |
Inflammation | 24.02 | 10.85 | 128 | 79853 | 28167 | 34848783 |
Gamma-glutamyltransferase increased | 23.98 | 10.85 | 19 | 79962 | 29212 | 34847738 |
Disturbance in attention | 23.85 | 10.85 | 120 | 79861 | 25825 | 34851125 |
Blindness | 23.80 | 10.85 | 82 | 79899 | 14904 | 34862046 |
Eye swelling | 23.72 | 10.85 | 63 | 79918 | 9932 | 34867018 |
Neuroleptic malignant syndrome | 23.51 | 10.85 | 6 | 79975 | 17928 | 34859022 |
Ulcer | 23.36 | 10.85 | 58 | 79923 | 8777 | 34868173 |
Electrocardiogram QT prolonged | 23.28 | 10.85 | 36 | 79945 | 40916 | 34836034 |
Intentional product misuse | 23.07 | 10.85 | 181 | 79800 | 45430 | 34831520 |
Gastroduodenal ulcer | 22.78 | 10.85 | 13 | 79968 | 375 | 34876575 |
Amnesia | 22.43 | 10.85 | 120 | 79861 | 26443 | 34850507 |
Gastrooesophageal reflux disease | 22.31 | 10.85 | 156 | 79825 | 37768 | 34839182 |
Acute myeloid leukaemia | 22.30 | 10.85 | 7 | 79974 | 18263 | 34858687 |
Metabolic alkalosis | 22.30 | 10.85 | 22 | 79959 | 1479 | 34875471 |
Diverticular perforation | 22.22 | 10.85 | 33 | 79948 | 3401 | 34873549 |
Acute biphenotypic leukaemia | 22.21 | 10.85 | 8 | 79973 | 74 | 34876876 |
Anaemia | 22.17 | 10.85 | 388 | 79593 | 232947 | 34644003 |
Foetal exposure during pregnancy | 22.14 | 10.85 | 33 | 79948 | 38068 | 34838882 |
Nasopharyngitis | 22.02 | 10.85 | 251 | 79730 | 69717 | 34807233 |
Penile swelling | 21.80 | 10.85 | 17 | 79964 | 833 | 34876117 |
Neck injury | 21.75 | 10.85 | 20 | 79961 | 1231 | 34875719 |
Confusional state | 21.64 | 10.85 | 218 | 79763 | 143942 | 34733008 |
Nightmare | 21.35 | 10.85 | 77 | 79904 | 14314 | 34862636 |
Energy increased | 21.09 | 10.85 | 20 | 79961 | 1280 | 34875670 |
Cardiogenic shock | 20.97 | 10.85 | 18 | 79963 | 26600 | 34850350 |
Mucosal inflammation | 20.97 | 10.85 | 35 | 79946 | 38587 | 34838363 |
Tendon disorder | 20.61 | 10.85 | 29 | 79952 | 2846 | 34874104 |
Hypercholesterolaemia | 20.56 | 10.85 | 55 | 79926 | 8707 | 34868243 |
Dry skin | 20.38 | 10.85 | 132 | 79849 | 31155 | 34845795 |
Respiratory tract malformation | 20.33 | 10.85 | 4 | 79977 | 0 | 34876950 |
Nail bed bleeding | 20.28 | 10.85 | 12 | 79969 | 371 | 34876579 |
Epilepsy | 20.26 | 10.85 | 12 | 79969 | 21483 | 34855467 |
Breath sounds abnormal | 20.15 | 10.85 | 47 | 79934 | 6834 | 34870116 |
Rheumatoid nodule | 20.05 | 10.85 | 29 | 79952 | 2918 | 34874032 |
Hiatus hernia | 20.01 | 10.85 | 50 | 79931 | 7595 | 34869355 |
Obstructive pancreatitis | 19.80 | 10.85 | 14 | 79967 | 590 | 34876360 |
Syndesmophyte | 19.72 | 10.85 | 8 | 79973 | 105 | 34876845 |
Musculoskeletal pain | 19.70 | 10.85 | 133 | 79848 | 31830 | 34845120 |
Tendon pain | 19.69 | 10.85 | 29 | 79952 | 2966 | 34873984 |
Failure of child resistant product closure | 19.65 | 10.85 | 6 | 79975 | 31 | 34876919 |
Extrapyramidal disorder | 19.62 | 10.85 | 3 | 79978 | 12877 | 34864073 |
Dysstasia | 19.60 | 10.85 | 67 | 79914 | 12128 | 34864822 |
Bone marrow failure | 19.38 | 10.85 | 23 | 79958 | 29230 | 34847720 |
Steatorrhoea | 19.36 | 10.85 | 15 | 79966 | 728 | 34876222 |
Iritis | 19.35 | 10.85 | 20 | 79961 | 1421 | 34875529 |
Venous angioma of brain | 19.34 | 10.85 | 6 | 79975 | 33 | 34876917 |
Fracture | 19.21 | 10.85 | 46 | 79935 | 6803 | 34870147 |
Status epilepticus | 19.07 | 10.85 | 3 | 79978 | 12611 | 34864339 |
Seizure | 19.05 | 10.85 | 151 | 79830 | 104706 | 34772244 |
Tuberculin test positive | 19.02 | 10.85 | 18 | 79963 | 1149 | 34875801 |
Kounis syndrome | 18.95 | 10.85 | 26 | 79955 | 2492 | 34874458 |
Chronic pigmented purpura | 18.94 | 10.85 | 8 | 79973 | 117 | 34876833 |
Blood pressure systolic increased | 18.92 | 10.85 | 103 | 79878 | 22849 | 34854101 |
Hepatitis B core antibody positive | 18.77 | 10.85 | 11 | 79970 | 334 | 34876616 |
Bacteraemia | 18.60 | 10.85 | 11 | 79970 | 19706 | 34857244 |
Hypervolaemia | 18.58 | 10.85 | 11 | 79970 | 19698 | 34857252 |
Tongue disorder | 18.49 | 10.85 | 39 | 79942 | 5300 | 34871650 |
Pneumonia aspiration | 18.41 | 10.85 | 43 | 79938 | 41860 | 34835090 |
Mobility decreased | 18.35 | 10.85 | 125 | 79856 | 30003 | 34846947 |
Aspergillus infection | 18.34 | 10.85 | 3 | 79978 | 12251 | 34864699 |
Fixed eruption | 18.30 | 10.85 | 21 | 79960 | 1679 | 34875271 |
Gangrene neonatal | 18.23 | 10.85 | 9 | 79972 | 192 | 34876758 |
Lymphocyte count decreased | 18.19 | 10.85 | 15 | 79966 | 22607 | 34854343 |
Arteriosclerosis coronary artery | 17.85 | 10.85 | 66 | 79915 | 12419 | 34864531 |
Acute respiratory failure | 17.76 | 10.85 | 27 | 79954 | 30901 | 34846049 |
Polyneuropathy | 17.67 | 10.85 | 6 | 79975 | 14890 | 34862060 |
Blood bilirubin unconjugated | 17.57 | 10.85 | 4 | 79977 | 4 | 34876946 |
Ventricular fibrillation | 17.51 | 10.85 | 16 | 79965 | 22938 | 34854012 |
Drug ineffective | 17.39 | 10.85 | 1240 | 78741 | 455511 | 34421439 |
Sensitivity to weather change | 17.36 | 10.85 | 20 | 79961 | 1606 | 34875344 |
Rectal haemorrhage | 17.30 | 10.85 | 154 | 79827 | 40095 | 34836855 |
Alopecia | 17.26 | 10.85 | 105 | 79876 | 24250 | 34852700 |
Bronchopulmonary aspergillosis | 17.22 | 10.85 | 6 | 79975 | 14653 | 34862297 |
Rash pruritic | 17.14 | 10.85 | 113 | 79868 | 26828 | 34850122 |
Nervous system neoplasm | 17.14 | 10.85 | 8 | 79973 | 150 | 34876800 |
Influenza like illness | 17.04 | 10.85 | 115 | 79866 | 27519 | 34849431 |
Chest pain | 16.81 | 10.85 | 394 | 79587 | 126368 | 34750582 |
Agranulocytosis | 16.57 | 10.85 | 18 | 79963 | 23803 | 34853147 |
Gastric ulcer perforation | 16.51 | 10.85 | 16 | 79965 | 1052 | 34875898 |
Lipoma | 16.40 | 10.85 | 20 | 79961 | 1706 | 34875244 |
Hepatotoxicity | 16.36 | 10.85 | 15 | 79966 | 21470 | 34855480 |
Weight decrease neonatal | 16.34 | 10.85 | 10 | 79971 | 329 | 34876621 |
Oral pustule | 16.34 | 10.85 | 9 | 79972 | 242 | 34876708 |
Clumsiness | 16.34 | 10.85 | 20 | 79961 | 1712 | 34875238 |
Renal failure | 16.22 | 10.85 | 206 | 79775 | 130351 | 34746599 |
Hypocalcaemia | 16.19 | 10.85 | 19 | 79962 | 24270 | 34852680 |
Pulmonary fibrosis | 16.15 | 10.85 | 84 | 79897 | 18312 | 34858638 |
Hypoaesthesia | 16.12 | 10.85 | 213 | 79768 | 61231 | 34815719 |
Gait disturbance | 16.07 | 10.85 | 279 | 79702 | 84861 | 34792089 |
Decreased appetite | 16.01 | 10.85 | 276 | 79705 | 166116 | 34710834 |
Tracheal atresia | 15.95 | 10.85 | 4 | 79977 | 8 | 34876942 |
Extra dose administered | 15.93 | 10.85 | 31 | 79950 | 3978 | 34872972 |
Pruritus | 15.50 | 10.85 | 430 | 79551 | 141551 | 34735399 |
Orthostatic hypotension | 15.50 | 10.85 | 22 | 79959 | 25897 | 34851053 |
Oesophageal injury | 15.35 | 10.85 | 5 | 79976 | 33 | 34876917 |
Undifferentiated connective tissue disease | 15.35 | 10.85 | 5 | 79976 | 33 | 34876917 |
Ankle fracture | 15.31 | 10.85 | 31 | 79950 | 4094 | 34872856 |
Joint range of motion decreased | 15.28 | 10.85 | 44 | 79937 | 7268 | 34869682 |
Skin turgor decreased | 15.22 | 10.85 | 11 | 79970 | 480 | 34876470 |
Swollen tongue | 15.19 | 10.85 | 70 | 79911 | 14535 | 34862415 |
Laryngospasm | 15.06 | 10.85 | 18 | 79963 | 1503 | 34875447 |
Eosinophilic pneumonia | 15.05 | 10.85 | 28 | 79953 | 3473 | 34873477 |
Ulcer haemorrhage | 14.95 | 10.85 | 24 | 79957 | 2646 | 34874304 |
Encephalopathy | 14.92 | 10.85 | 37 | 79944 | 35282 | 34841668 |
Renal arteriosclerosis | 14.91 | 10.85 | 8 | 79973 | 204 | 34876746 |
Diverticulum | 14.89 | 10.85 | 43 | 79938 | 7116 | 34869834 |
Memory impairment | 14.82 | 10.85 | 158 | 79823 | 43160 | 34833790 |
Intervertebral disc degeneration | 14.78 | 10.85 | 40 | 79941 | 6377 | 34870573 |
Congenital umbilical hernia | 14.74 | 10.85 | 9 | 79972 | 295 | 34876655 |
Acute respiratory distress syndrome | 14.60 | 10.85 | 23 | 79958 | 25946 | 34851004 |
Drug intolerance | 14.60 | 10.85 | 204 | 79777 | 59366 | 34817584 |
Secondary amyloidosis | 14.57 | 10.85 | 6 | 79975 | 82 | 34876868 |
Back injury | 14.56 | 10.85 | 30 | 79951 | 4011 | 34872939 |
Moaning | 14.51 | 10.85 | 13 | 79968 | 773 | 34876177 |
Dyspepsia | 14.50 | 10.85 | 138 | 79843 | 36594 | 34840356 |
Spondyloarthropathy | 14.46 | 10.85 | 12 | 79969 | 643 | 34876307 |
Lymphocyte count | 14.44 | 10.85 | 6 | 79975 | 84 | 34876866 |
Inflammatory pain | 14.40 | 10.85 | 8 | 79973 | 219 | 34876731 |
Inappropriate schedule of product administration | 14.34 | 10.85 | 211 | 79770 | 62085 | 34814865 |
Drug ineffective for unapproved indication | 14.31 | 10.85 | 20 | 79961 | 23695 | 34853255 |
Blood lactate dehydrogenase increased | 14.26 | 10.85 | 19 | 79962 | 22971 | 34853979 |
Incorrect dosage administered | 14.24 | 10.85 | 16 | 79965 | 1250 | 34875700 |
Coma | 14.22 | 10.85 | 55 | 79926 | 45623 | 34831327 |
Neck mass | 14.22 | 10.85 | 18 | 79963 | 1595 | 34875355 |
Peptic ulcer perforation | 14.14 | 10.85 | 8 | 79973 | 227 | 34876723 |
Dizziness | 14.12 | 10.85 | 623 | 79358 | 217898 | 34659052 |
Arrhythmia | 13.99 | 10.85 | 39 | 79942 | 35769 | 34841181 |
Restlessness | 13.92 | 10.85 | 23 | 79958 | 25459 | 34851491 |
Peptic ulcer haemorrhage | 13.92 | 10.85 | 11 | 79970 | 550 | 34876400 |
Arthroscopy | 13.77 | 10.85 | 6 | 79975 | 95 | 34876855 |
Hallucination | 13.70 | 10.85 | 179 | 79802 | 51319 | 34825631 |
Pleural effusion | 13.64 | 10.85 | 120 | 79861 | 81426 | 34795524 |
Application site haematoma | 13.63 | 10.85 | 5 | 79976 | 49 | 34876901 |
Red blood cell sedimentation rate increased | 13.57 | 10.85 | 49 | 79932 | 9113 | 34867837 |
Swelling face | 13.56 | 10.85 | 95 | 79886 | 23010 | 34853940 |
Dystonia | 13.52 | 10.85 | 4 | 79977 | 10841 | 34866109 |
Bone hypertrophy | 13.51 | 10.85 | 7 | 79974 | 166 | 34876784 |
Throat tightness | 13.50 | 10.85 | 46 | 79935 | 8312 | 34868638 |
Lactic acidosis | 13.49 | 10.85 | 38 | 79943 | 34734 | 34842216 |
Micturition urgency | 13.38 | 10.85 | 39 | 79942 | 6486 | 34870464 |
Renal impairment | 13.32 | 10.85 | 145 | 79836 | 94368 | 34782582 |
Progressive multifocal leukoencephalopathy | 13.32 | 10.85 | 3 | 79978 | 9761 | 34867189 |
Deep vein thrombosis | 13.26 | 10.85 | 91 | 79890 | 65157 | 34811793 |
Hypotension | 13.26 | 10.85 | 396 | 79585 | 221253 | 34655697 |
Depression | 13.23 | 10.85 | 303 | 79678 | 96795 | 34780155 |
Tenosynovitis | 13.15 | 10.85 | 31 | 79950 | 4539 | 34872411 |
Appendicitis | 12.95 | 10.85 | 9 | 79972 | 14798 | 34862152 |
Pulmonary embolism | 12.93 | 10.85 | 137 | 79844 | 89609 | 34787341 |
Lymphopenia | 12.93 | 10.85 | 11 | 79970 | 16324 | 34860626 |
Myelodysplastic syndrome | 12.83 | 10.85 | 15 | 79966 | 19193 | 34857757 |
Product label issue | 12.81 | 10.85 | 8 | 79973 | 273 | 34876677 |
Toxic skin eruption | 12.80 | 10.85 | 5 | 79976 | 11380 | 34865570 |
Hypoxia | 12.66 | 10.85 | 74 | 79907 | 55021 | 34821929 |
Hyperglycaemia | 12.64 | 10.85 | 47 | 79934 | 39433 | 34837517 |
Pneumocystis jirovecii pneumonia | 12.52 | 10.85 | 16 | 79965 | 19694 | 34857256 |
Rheumatoid lung | 12.52 | 10.85 | 13 | 79968 | 929 | 34876021 |
Loss of proprioception | 12.49 | 10.85 | 9 | 79972 | 391 | 34876559 |
Hepatic failure | 12.48 | 10.85 | 39 | 79942 | 34492 | 34842458 |
Atrioventricular block complete | 12.44 | 10.85 | 3 | 79978 | 9316 | 34867634 |
Malignant neoplasm progression | 12.44 | 10.85 | 135 | 79846 | 87911 | 34789039 |
Fluid retention | 12.29 | 10.85 | 27 | 79954 | 26860 | 34850090 |
Inappropriate antidiuretic hormone secretion | 12.19 | 10.85 | 7 | 79974 | 12746 | 34864204 |
Disease recurrence | 12.11 | 10.85 | 19 | 79962 | 21471 | 34855479 |
Skin irritation | 12.08 | 10.85 | 34 | 79947 | 5543 | 34871407 |
Fibromuscular dysplasia | 11.97 | 10.85 | 3 | 79978 | 6 | 34876944 |
Thrombocytosis | 11.95 | 10.85 | 28 | 79953 | 4084 | 34872866 |
Tooth disorder | 11.95 | 10.85 | 53 | 79928 | 10829 | 34866121 |
Haemangioma | 11.95 | 10.85 | 18 | 79963 | 1879 | 34875071 |
Ligament calcification | 11.93 | 10.85 | 7 | 79974 | 213 | 34876737 |
Benign prostatic hyperplasia | 11.91 | 10.85 | 65 | 79916 | 14430 | 34862520 |
Oral pruritus | 11.91 | 10.85 | 8 | 79973 | 310 | 34876640 |
Respiratory arrest | 11.90 | 10.85 | 107 | 79874 | 27936 | 34849014 |
Fatigue | 11.87 | 10.85 | 993 | 78988 | 369660 | 34507290 |
Lumbar radiculopathy | 11.85 | 10.85 | 12 | 79969 | 832 | 34876118 |
Neoplasm progression | 11.84 | 10.85 | 22 | 79959 | 23278 | 34853672 |
Malaise | 11.83 | 10.85 | 529 | 79452 | 185296 | 34691654 |
Nail injury | 11.72 | 10.85 | 4 | 79977 | 31 | 34876919 |
Analgesic drug level increased | 11.71 | 10.85 | 12 | 79969 | 844 | 34876106 |
Vanishing bile duct syndrome | 11.68 | 10.85 | 13 | 79968 | 1005 | 34875945 |
Red blood cell sedimentation rate | 11.67 | 10.85 | 14 | 79967 | 1174 | 34875776 |
Burning sensation | 11.61 | 10.85 | 77 | 79904 | 18317 | 34858633 |
COVID-19 pneumonia | 11.60 | 10.85 | 13 | 79968 | 16954 | 34859996 |
Proctitis ulcerative | 11.60 | 10.85 | 5 | 79976 | 77 | 34876873 |
Steatohepatitis | 11.60 | 10.85 | 8 | 79973 | 324 | 34876626 |
Peripheral artery thrombosis | 11.59 | 10.85 | 20 | 79961 | 2340 | 34874610 |
Post-traumatic neck syndrome | 11.55 | 10.85 | 6 | 79975 | 143 | 34876807 |
Pseudomonas infection | 11.55 | 10.85 | 7 | 79974 | 12375 | 34864575 |
Blood creatine phosphokinase increased | 11.54 | 10.85 | 58 | 79923 | 44799 | 34832151 |
Tandem gait test abnormal | 11.51 | 10.85 | 4 | 79977 | 33 | 34876917 |
Hyperbilirubinaemia | 11.41 | 10.85 | 13 | 79968 | 16830 | 34860120 |
Priapism | 11.37 | 10.85 | 31 | 79950 | 4963 | 34871987 |
Alcoholic hangover | 11.37 | 10.85 | 3 | 79978 | 8 | 34876942 |
Alcohol use | 11.37 | 10.85 | 24 | 79957 | 3264 | 34873686 |
Therapeutic response shortened | 11.31 | 10.85 | 40 | 79941 | 7364 | 34869586 |
Blood cholesterol increased | 11.21 | 10.85 | 83 | 79898 | 20460 | 34856490 |
Swelling | 11.16 | 10.85 | 147 | 79834 | 42219 | 34834731 |
Overdose | 11.15 | 10.85 | 280 | 79701 | 90779 | 34786171 |
Sopor | 11.12 | 10.85 | 7 | 79974 | 12129 | 34864821 |
Salivary hypersecretion | 11.12 | 10.85 | 3 | 79978 | 8641 | 34868309 |
Swollen joint count decreased | 11.08 | 10.85 | 6 | 79975 | 156 | 34876794 |
Tender joint count decreased | 11.08 | 10.85 | 6 | 79975 | 156 | 34876794 |
Pneumonitis | 11.06 | 10.85 | 40 | 79941 | 33838 | 34843112 |
Neurotoxicity | 11.05 | 10.85 | 15 | 79966 | 17995 | 34858955 |
Failure to thrive | 11.04 | 10.85 | 3 | 79978 | 8598 | 34868352 |
Local reaction | 10.95 | 10.85 | 5 | 79976 | 89 | 34876861 |
Cognitive disorder | 10.93 | 10.85 | 107 | 79874 | 28586 | 34848364 |
Klebsiella infection | 10.90 | 10.85 | 3 | 79978 | 8528 | 34868422 |
Joint lock | 10.88 | 10.85 | 14 | 79967 | 1261 | 34875689 |
Intentional overdose | 10.87 | 10.85 | 150 | 79831 | 43524 | 34833426 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Psoriatic arthropathy | 513.67 | 10.08 | 926 | 263846 | 77073 | 79402543 |
Ankylosing spondylitis | 475.80 | 10.08 | 364 | 264408 | 11841 | 79467775 |
C-reactive protein abnormal | 452.42 | 10.08 | 673 | 264099 | 47694 | 79431922 |
Musculoskeletal stiffness | 441.14 | 10.08 | 1431 | 263341 | 173577 | 79306039 |
Death | 440.11 | 10.08 | 754 | 264018 | 565760 | 78913856 |
Rheumatoid arthritis | 436.09 | 10.08 | 1602 | 263170 | 206868 | 79272748 |
Arthralgia | 392.64 | 10.08 | 3238 | 261534 | 568565 | 78911051 |
Synovitis | 373.91 | 10.08 | 1226 | 263546 | 149508 | 79330108 |
Pain | 365.22 | 10.08 | 3752 | 261020 | 700050 | 78779566 |
Joint swelling | 352.82 | 10.08 | 1889 | 262883 | 286757 | 79192859 |
Neutropenia | 327.63 | 10.08 | 284 | 264488 | 287426 | 79192190 |
Arthropathy | 321.90 | 10.08 | 1302 | 263470 | 175809 | 79303807 |
Red blood cell sedimentation rate abnormal | 311.27 | 10.08 | 366 | 264406 | 20597 | 79459019 |
Fibromyalgia | 311.01 | 10.08 | 671 | 264101 | 63669 | 79415947 |
Febrile neutropenia | 302.82 | 10.08 | 197 | 264575 | 230802 | 79248814 |
Drug hypersensitivity | 259.96 | 10.08 | 1791 | 262981 | 297125 | 79182491 |
Pancytopenia | 254.07 | 10.08 | 116 | 264656 | 165629 | 79313987 |
Migraine | 241.88 | 10.08 | 739 | 264033 | 86754 | 79392862 |
Sepsis | 239.09 | 10.08 | 327 | 264445 | 269101 | 79210515 |
Thrombocytopenia | 227.36 | 10.08 | 330 | 264442 | 264929 | 79214687 |
Drug intolerance | 219.29 | 10.08 | 1565 | 263207 | 262554 | 79217062 |
Psoriasis | 217.82 | 10.08 | 724 | 264048 | 88863 | 79390753 |
Cardiac failure | 212.64 | 10.08 | 125 | 264647 | 154717 | 79324899 |
Arthritis | 208.96 | 10.08 | 845 | 263927 | 114035 | 79365581 |
Anaemia | 206.66 | 10.08 | 770 | 264002 | 444245 | 79035371 |
Leukopenia | 189.00 | 10.08 | 75 | 264697 | 116438 | 79363178 |
Pain in extremity | 188.51 | 10.08 | 1944 | 262828 | 362594 | 79117022 |
Pneumonia | 186.63 | 10.08 | 1355 | 263417 | 658891 | 78820725 |
Drug interaction | 185.88 | 10.08 | 729 | 264043 | 414454 | 79065162 |
Rheumatoid nodule | 181.03 | 10.08 | 255 | 264517 | 17183 | 79462433 |
Drug ineffective | 179.80 | 10.08 | 4774 | 259998 | 1076139 | 78403477 |
Hyponatraemia | 179.74 | 10.08 | 195 | 264577 | 177653 | 79301963 |
Lip swelling | 176.70 | 10.08 | 408 | 264364 | 40503 | 79439113 |
Gastric haemorrhage | 172.69 | 10.08 | 231 | 264541 | 14819 | 79464797 |
Abdominal pain upper | 171.86 | 10.08 | 1302 | 263470 | 222517 | 79257099 |
Cardiospasm | 168.66 | 10.08 | 116 | 264656 | 3185 | 79476431 |
Contraindicated product administered | 164.46 | 10.08 | 989 | 263783 | 156549 | 79323067 |
Disease progression | 163.23 | 10.08 | 224 | 264548 | 184138 | 79295478 |
Pyrexia | 161.86 | 10.08 | 1458 | 263314 | 677251 | 78802365 |
Grip strength decreased | 159.91 | 10.08 | 272 | 264500 | 21597 | 79458019 |
Gastric ulcer | 155.18 | 10.08 | 346 | 264426 | 33559 | 79446057 |
Palmoplantar keratoderma | 151.84 | 10.08 | 114 | 264658 | 3602 | 79476014 |
Duodenal ulcer | 150.48 | 10.08 | 226 | 264546 | 16143 | 79463473 |
Pruritus genital | 147.39 | 10.08 | 121 | 264651 | 4365 | 79475251 |
Mobility decreased | 145.85 | 10.08 | 795 | 263977 | 121380 | 79358236 |
Bradycardia | 144.45 | 10.08 | 142 | 264630 | 135415 | 79344201 |
Inflammation | 140.81 | 10.08 | 651 | 264121 | 93102 | 79386514 |
Drug abuse | 139.70 | 10.08 | 202 | 264570 | 162489 | 79317127 |
Polyarthritis | 138.04 | 10.08 | 186 | 264586 | 12016 | 79467600 |
Injury | 136.10 | 10.08 | 564 | 264208 | 76932 | 79402684 |
Sleep terror | 135.59 | 10.08 | 115 | 264657 | 4343 | 79475273 |
Musculoskeletal disorder | 135.22 | 10.08 | 250 | 264522 | 21198 | 79458418 |
Joint destruction | 133.29 | 10.08 | 129 | 264643 | 5796 | 79473820 |
Dislocation of vertebra | 132.92 | 10.08 | 147 | 264625 | 7733 | 79471883 |
Platelet count decreased | 132.36 | 10.08 | 280 | 264492 | 194384 | 79285232 |
Human antichimeric antibody positive | 129.75 | 10.08 | 76 | 264696 | 1565 | 79478051 |
Peripheral swelling | 129.48 | 10.08 | 1417 | 263355 | 268200 | 79211416 |
Drug tolerance | 126.35 | 10.08 | 150 | 264622 | 8525 | 79471091 |
Body height below normal | 126.31 | 10.08 | 81 | 264691 | 1972 | 79477644 |
C-reactive protein increased | 125.81 | 10.08 | 796 | 263976 | 128231 | 79351385 |
Hypoaesthesia | 122.08 | 10.08 | 1015 | 263757 | 178337 | 79301279 |
Tension headache | 120.74 | 10.08 | 134 | 264638 | 7077 | 79472539 |
Abdominal discomfort | 119.12 | 10.08 | 1315 | 263457 | 249412 | 79230204 |
Therapeutic product effect decreased | 118.36 | 10.08 | 940 | 263832 | 162923 | 79316693 |
Neck pain | 114.96 | 10.08 | 526 | 264246 | 74891 | 79404725 |
Seronegative arthritis | 114.78 | 10.08 | 107 | 264665 | 4585 | 79475031 |
Cytomegalovirus infection | 113.57 | 10.08 | 7 | 264765 | 42637 | 79436979 |
Atrial fibrillation | 110.68 | 10.08 | 315 | 264457 | 197571 | 79282045 |
Musculoskeletal pain | 110.25 | 10.08 | 648 | 264124 | 101706 | 79377910 |
Joint laxity | 109.57 | 10.08 | 78 | 264694 | 2266 | 79477350 |
Drug tolerance decreased | 109.20 | 10.08 | 172 | 264600 | 12806 | 79466810 |
Joint range of motion decreased | 109.19 | 10.08 | 299 | 264473 | 32983 | 79446633 |
Immunisation | 108.01 | 10.08 | 75 | 264697 | 2092 | 79477524 |
Drug resistance | 106.48 | 10.08 | 9 | 264763 | 42204 | 79437412 |
Hypoglycaemia | 106.42 | 10.08 | 108 | 264664 | 101486 | 79378130 |
Carotid artery occlusion | 106.09 | 10.08 | 129 | 264643 | 7518 | 79472098 |
Hypotension | 105.56 | 10.08 | 944 | 263828 | 439373 | 79040243 |
Obesity | 104.91 | 10.08 | 305 | 264467 | 34820 | 79444796 |
Respiratory failure | 103.38 | 10.08 | 285 | 264487 | 180626 | 79298990 |
Pharyngitis | 103.13 | 10.08 | 229 | 264543 | 22146 | 79457470 |
Angioedema | 102.61 | 10.08 | 512 | 264260 | 75523 | 79404093 |
Impaired healing | 102.32 | 10.08 | 567 | 264205 | 87088 | 79392528 |
Cardiac failure congestive | 101.74 | 10.08 | 199 | 264573 | 142203 | 79337413 |
Impaired work ability | 100.54 | 10.08 | 210 | 264562 | 19471 | 79460145 |
Malignant neoplasm progression | 99.81 | 10.08 | 187 | 264585 | 135803 | 79343813 |
Gastrointestinal pain | 99.17 | 10.08 | 142 | 264630 | 9713 | 79469903 |
Disability | 98.58 | 10.08 | 192 | 264580 | 16928 | 79462688 |
Foot deformity | 98.40 | 10.08 | 235 | 264537 | 23839 | 79455777 |
Atrial tachycardia | 96.81 | 10.08 | 119 | 264653 | 7014 | 79472602 |
Off label use | 94.91 | 10.08 | 2292 | 262480 | 904923 | 78574693 |
Multiple organ dysfunction syndrome | 94.89 | 10.08 | 158 | 264614 | 120088 | 79359528 |
Loose body in joint | 94.62 | 10.08 | 57 | 264715 | 1238 | 79478378 |
Upper gastrointestinal haemorrhage | 94.01 | 10.08 | 327 | 264445 | 41053 | 79438563 |
Enthesopathy | 93.76 | 10.08 | 151 | 264621 | 11457 | 79468159 |
Joint effusion | 92.94 | 10.08 | 193 | 264579 | 17821 | 79461795 |
Cytokine release syndrome | 92.68 | 10.08 | 7 | 264765 | 35991 | 79443625 |
Anosmia | 91.31 | 10.08 | 129 | 264643 | 8715 | 79470901 |
Duodenal ulcer haemorrhage | 90.03 | 10.08 | 115 | 264657 | 7048 | 79472568 |
Neutrophil count decreased | 89.48 | 10.08 | 108 | 264664 | 93851 | 79385765 |
Renal impairment | 89.07 | 10.08 | 250 | 264522 | 157533 | 79322083 |
Renal failure | 87.79 | 10.08 | 356 | 264416 | 200612 | 79279004 |
Ascites | 86.60 | 10.08 | 74 | 264698 | 75488 | 79404128 |
Femur fracture | 86.56 | 10.08 | 304 | 264468 | 38348 | 79441268 |
Orthostatic hypotension | 86.50 | 10.08 | 39 | 264733 | 56125 | 79423491 |
Ulcer | 86.40 | 10.08 | 257 | 264515 | 29715 | 79449901 |
Pseudoporphyria | 86.21 | 10.08 | 42 | 264730 | 586 | 79479030 |
White blood cell count decreased | 85.77 | 10.08 | 328 | 264444 | 187960 | 79291656 |
Tenosynovitis | 85.41 | 10.08 | 171 | 264601 | 15383 | 79464233 |
Liver injury | 83.42 | 10.08 | 391 | 264381 | 56223 | 79423393 |
Foot operation | 83.28 | 10.08 | 99 | 264673 | 5634 | 79473982 |
Pain of skin | 83.07 | 10.08 | 163 | 264609 | 14450 | 79465166 |
Systemic lupus erythematosus rash | 82.61 | 10.08 | 60 | 264712 | 1800 | 79477816 |
Gait inability | 81.82 | 10.08 | 400 | 264372 | 58517 | 79421099 |
Facial pain | 81.71 | 10.08 | 147 | 264625 | 12203 | 79467413 |
Red blood cell sedimentation rate increased | 81.15 | 10.08 | 335 | 264437 | 45607 | 79434009 |
Deafness transitory | 81.10 | 10.08 | 47 | 264725 | 948 | 79478668 |
Gastric ulcer haemorrhage | 80.66 | 10.08 | 123 | 264649 | 8904 | 79470712 |
Tendonitis | 80.08 | 10.08 | 216 | 264556 | 23614 | 79456002 |
Adjustment disorder with depressed mood | 80.05 | 10.08 | 123 | 264649 | 8963 | 79470653 |
Hepatic function abnormal | 79.70 | 10.08 | 75 | 264697 | 73032 | 79406584 |
Prescribed overdose | 78.92 | 10.08 | 291 | 264481 | 37592 | 79442024 |
Wound infection | 78.17 | 10.08 | 215 | 264557 | 23776 | 79455840 |
Wheelchair user | 77.95 | 10.08 | 99 | 264673 | 6033 | 79473583 |
Urticaria | 77.92 | 10.08 | 949 | 263823 | 184252 | 79295364 |
Swelling | 77.57 | 10.08 | 1078 | 263694 | 215633 | 79263983 |
Amnesia | 77.02 | 10.08 | 413 | 264359 | 62644 | 79416972 |
Bursitis | 76.92 | 10.08 | 278 | 264494 | 35566 | 79444050 |
Shoulder arthroplasty | 76.75 | 10.08 | 73 | 264699 | 3209 | 79476407 |
Red blood cell sedimentation rate | 75.78 | 10.08 | 93 | 264679 | 5472 | 79474144 |
Gamma-glutamyltransferase increased | 75.22 | 10.08 | 44 | 264728 | 54636 | 79424980 |
Hypoxia | 74.85 | 10.08 | 143 | 264629 | 103100 | 79376516 |
Posterior reversible encephalopathy syndrome | 74.16 | 10.08 | 3 | 264769 | 26278 | 79453338 |
Haematemesis | 73.41 | 10.08 | 356 | 264416 | 51908 | 79427708 |
Tenosynovitis stenosans | 73.00 | 10.08 | 69 | 264703 | 3009 | 79476607 |
Nerve injury | 72.91 | 10.08 | 120 | 264652 | 9272 | 79470344 |
Confusional state | 72.57 | 10.08 | 690 | 264082 | 317307 | 79162309 |
Myelosuppression | 72.10 | 10.08 | 22 | 264750 | 40274 | 79439342 |
Dyspnoea | 71.47 | 10.08 | 2235 | 262537 | 854790 | 78624826 |
Bone density decreased | 71.22 | 10.08 | 145 | 264627 | 13202 | 79466414 |
Facet joint syndrome | 70.32 | 10.08 | 131 | 264641 | 11171 | 79468445 |
Lip dry | 70.16 | 10.08 | 157 | 264615 | 15261 | 79464355 |
Hypomagnesaemia | 70.04 | 10.08 | 34 | 264738 | 46877 | 79432739 |
Congenital hiatus hernia | 70.04 | 10.08 | 40 | 264732 | 784 | 79478832 |
Toothache | 68.10 | 10.08 | 182 | 264590 | 19788 | 79459828 |
Joint injury | 67.21 | 10.08 | 243 | 264529 | 31092 | 79448524 |
Nephrolithiasis | 67.11 | 10.08 | 352 | 264420 | 52939 | 79426677 |
Blood cholesterol increased | 66.40 | 10.08 | 491 | 264281 | 83229 | 79396387 |
Respiratory tract congestion | 66.18 | 10.08 | 180 | 264592 | 19774 | 79459842 |
Back pain | 66.13 | 10.08 | 1396 | 263376 | 302784 | 79176832 |
Memory impairment | 65.95 | 10.08 | 613 | 264159 | 111121 | 79368495 |
Fear of injection | 64.20 | 10.08 | 100 | 264672 | 7374 | 79472242 |
Osteoporosis | 63.78 | 10.08 | 351 | 264421 | 53761 | 79425855 |
Swollen joint count increased | 63.64 | 10.08 | 194 | 264578 | 22733 | 79456883 |
Rash | 63.56 | 10.08 | 2433 | 262339 | 575925 | 78903691 |
Multiple fractures | 62.92 | 10.08 | 103 | 264669 | 7923 | 79471693 |
Encephalopathy | 62.56 | 10.08 | 79 | 264693 | 67318 | 79412298 |
Deep vein thrombosis postoperative | 62.41 | 10.08 | 121 | 264651 | 10631 | 79468985 |
Synovial fluid analysis | 61.99 | 10.08 | 56 | 264716 | 2303 | 79477313 |
Cholecystitis chronic | 61.85 | 10.08 | 115 | 264657 | 9791 | 79469825 |
Dizziness | 61.78 | 10.08 | 2231 | 262541 | 524210 | 78955406 |
Acute respiratory failure | 61.55 | 10.08 | 64 | 264708 | 59477 | 79420139 |
Bone marrow failure | 61.10 | 10.08 | 48 | 264724 | 51059 | 79428557 |
Hypervolaemia | 60.67 | 10.08 | 33 | 264739 | 42657 | 79436959 |
Constipation | 60.04 | 10.08 | 625 | 264147 | 282425 | 79197191 |
Blepharospasm | 59.90 | 10.08 | 85 | 264687 | 5766 | 79473850 |
Dehydration | 59.41 | 10.08 | 532 | 264240 | 247655 | 79231961 |
Swelling face | 58.97 | 10.08 | 422 | 264350 | 70790 | 79408826 |
Hospitalisation | 58.76 | 10.08 | 142 | 264630 | 94094 | 79385522 |
Rheumatic fever | 58.48 | 10.08 | 218 | 264554 | 28307 | 79451309 |
Agranulocytosis | 58.13 | 10.08 | 39 | 264733 | 44991 | 79434625 |
Eye pruritus | 57.98 | 10.08 | 175 | 264597 | 20395 | 79459221 |
Limb discomfort | 57.59 | 10.08 | 239 | 264533 | 32611 | 79447005 |
Pleuritic pain | 57.41 | 10.08 | 113 | 264659 | 10039 | 79469577 |
Cardiogenic shock | 57.27 | 10.08 | 34 | 264738 | 41880 | 79437736 |
Neuroleptic malignant syndrome | 57.21 | 10.08 | 11 | 264761 | 27548 | 79452068 |
Mucosal inflammation | 57.16 | 10.08 | 102 | 264670 | 75478 | 79404138 |
Hyperglycaemia | 56.81 | 10.08 | 91 | 264681 | 70244 | 79409372 |
Osteoarthritis | 56.65 | 10.08 | 489 | 264283 | 86820 | 79392796 |
IgM nephropathy | 55.98 | 10.08 | 20 | 264752 | 118 | 79479498 |
Sopor | 55.59 | 10.08 | 20 | 264752 | 32990 | 79446626 |
Drug specific antibody | 54.99 | 10.08 | 55 | 264717 | 2573 | 79477043 |
Thrombotic microangiopathy | 54.66 | 10.08 | 3 | 264769 | 20166 | 79459450 |
Nodule | 54.23 | 10.08 | 184 | 264588 | 22810 | 79456806 |
Hypokalaemia | 53.40 | 10.08 | 271 | 264501 | 143769 | 79335847 |
Acute myeloid leukaemia | 53.24 | 10.08 | 18 | 264754 | 30867 | 79448749 |
Seizure | 52.88 | 10.08 | 388 | 264384 | 188446 | 79291170 |
Dactylitis | 52.78 | 10.08 | 55 | 264717 | 2702 | 79476914 |
Bone disorder | 52.37 | 10.08 | 161 | 264611 | 18952 | 79460664 |
Mycotic allergy | 52.07 | 10.08 | 42 | 264730 | 1477 | 79478139 |
Neoplasm progression | 51.80 | 10.08 | 57 | 264715 | 51625 | 79427991 |
Scleritis | 51.73 | 10.08 | 68 | 264704 | 4288 | 79475328 |
Aspergillus infection | 51.46 | 10.08 | 3 | 264769 | 19158 | 79460458 |
Dyspepsia | 51.05 | 10.08 | 569 | 264203 | 108118 | 79371498 |
Cardiac arrest | 50.93 | 10.08 | 348 | 264424 | 171748 | 79307868 |
Pulmonary hypertension | 50.47 | 10.08 | 51 | 264721 | 48029 | 79431587 |
Gastrooesophageal reflux disease | 50.46 | 10.08 | 549 | 264223 | 103697 | 79375919 |
Blood creatine phosphokinase increased | 50.15 | 10.08 | 89 | 264683 | 66001 | 79413615 |
Cerebral haemorrhage | 50.07 | 10.08 | 71 | 264701 | 57602 | 79422014 |
Loss of personal independence in daily activities | 50.01 | 10.08 | 541 | 264231 | 102039 | 79377577 |
Sacroiliitis | 49.93 | 10.08 | 62 | 264710 | 3692 | 79475924 |
Pulmonary arterial hypertension | 49.83 | 10.08 | 16 | 264756 | 28350 | 79451266 |
Synovial cyst | 49.79 | 10.08 | 106 | 264666 | 9959 | 79469657 |
Electrocardiogram QT prolonged | 49.68 | 10.08 | 145 | 264627 | 90241 | 79389375 |
Syncope | 49.63 | 10.08 | 370 | 264402 | 179079 | 79300537 |
Wrist deformity | 49.34 | 10.08 | 47 | 264725 | 2070 | 79477546 |
Musculoskeletal discomfort | 48.80 | 10.08 | 161 | 264611 | 19674 | 79459942 |
Osteonecrosis of jaw | 48.71 | 10.08 | 43 | 264729 | 43183 | 79436433 |
Respiratory distress | 48.52 | 10.08 | 74 | 264698 | 58265 | 79421351 |
Peripheral venous disease | 48.33 | 10.08 | 139 | 264633 | 15770 | 79463846 |
Ventricular fibrillation | 47.87 | 10.08 | 23 | 264749 | 31903 | 79447713 |
Melaena | 47.65 | 10.08 | 356 | 264416 | 60534 | 79419082 |
Blood parathyroid hormone decreased | 47.62 | 10.08 | 107 | 264665 | 10429 | 79469187 |
Type 2 diabetes mellitus | 47.58 | 10.08 | 339 | 264433 | 56783 | 79422833 |
Bunion operation | 47.57 | 10.08 | 33 | 264739 | 919 | 79478697 |
Clostridium difficile colitis | 47.28 | 10.08 | 24 | 264748 | 32259 | 79447357 |
Dysstasia | 47.18 | 10.08 | 200 | 264572 | 27546 | 79452070 |
Acute respiratory distress syndrome | 47.11 | 10.08 | 46 | 264726 | 44021 | 79435595 |
Hip arthroplasty | 46.98 | 10.08 | 239 | 264533 | 35517 | 79444099 |
Myelodysplastic syndrome | 46.72 | 10.08 | 21 | 264751 | 30280 | 79449336 |
Septic shock | 46.69 | 10.08 | 229 | 264543 | 122572 | 79357044 |
Faeces discoloured | 46.50 | 10.08 | 206 | 264566 | 28921 | 79450695 |
Malaise | 46.45 | 10.08 | 2029 | 262743 | 487840 | 78991776 |
Tongue disorder | 46.28 | 10.08 | 126 | 264646 | 13849 | 79465767 |
Neuropathy peripheral | 46.28 | 10.08 | 277 | 264495 | 141028 | 79338588 |
Emotional distress | 46.26 | 10.08 | 258 | 264514 | 39711 | 79439905 |
Bronchopulmonary aspergillosis | 46.07 | 10.08 | 9 | 264763 | 22285 | 79457331 |
Neovascularisation | 46.05 | 10.08 | 36 | 264736 | 1209 | 79478407 |
Nasopharyngitis | 46.05 | 10.08 | 1136 | 263636 | 252745 | 79226871 |
Knee arthroplasty | 46.02 | 10.08 | 273 | 264499 | 42975 | 79436641 |
Tinnitus | 46.00 | 10.08 | 278 | 264494 | 44055 | 79435561 |
International normalised ratio increased | 45.77 | 10.08 | 137 | 264635 | 84584 | 79395032 |
Feeling abnormal | 45.75 | 10.08 | 763 | 264009 | 158436 | 79321180 |
Bacteraemia | 45.74 | 10.08 | 26 | 264746 | 32798 | 79446818 |
Autoimmune disorder | 45.58 | 10.08 | 140 | 264632 | 16472 | 79463144 |
Therapy non-responder | 44.62 | 10.08 | 486 | 264286 | 91819 | 79387797 |
Cartilage atrophy | 44.48 | 10.08 | 18 | 264754 | 156 | 79479460 |
Muscle twitching | 44.06 | 10.08 | 181 | 264591 | 24583 | 79455033 |
Rheumatoid lung | 43.94 | 10.08 | 62 | 264710 | 4183 | 79475433 |
Tooth disorder | 43.76 | 10.08 | 188 | 264584 | 26045 | 79453571 |
Electrolyte imbalance | 43.69 | 10.08 | 24 | 264748 | 30857 | 79448759 |
Neurotoxicity | 43.56 | 10.08 | 27 | 264745 | 32491 | 79447125 |
Hand deformity | 43.45 | 10.08 | 532 | 264240 | 103387 | 79376229 |
Rash pruritic | 43.27 | 10.08 | 395 | 264377 | 71234 | 79408382 |
Arrhythmia | 42.56 | 10.08 | 87 | 264685 | 61185 | 79418431 |
Granuloma skin | 42.39 | 10.08 | 94 | 264678 | 9080 | 79470536 |
Tenderness | 42.22 | 10.08 | 173 | 264599 | 23469 | 79456147 |
Adrenal insufficiency | 42.15 | 10.08 | 197 | 264575 | 28290 | 79451326 |
Hepatotoxicity | 41.88 | 10.08 | 66 | 264706 | 51286 | 79428330 |
Antibody test positive | 41.86 | 10.08 | 49 | 264723 | 2743 | 79476873 |
Right ventricular failure | 41.73 | 10.08 | 13 | 264759 | 23484 | 79456132 |
Accidental exposure to product by child | 41.64 | 10.08 | 50 | 264722 | 2876 | 79476740 |
Night sweats | 41.57 | 10.08 | 306 | 264466 | 51789 | 79427827 |
Anxiety | 41.55 | 10.08 | 1100 | 263672 | 247412 | 79232204 |
Duodenal ulcer perforation | 41.47 | 10.08 | 368 | 264404 | 65843 | 79413773 |
Psychotic disorder | 41.12 | 10.08 | 46 | 264726 | 41356 | 79438260 |
Osteoporotic fracture | 41.07 | 10.08 | 60 | 264712 | 4180 | 79475436 |
Transient ischaemic attack | 40.62 | 10.08 | 307 | 264465 | 52388 | 79427228 |
Hunger | 40.32 | 10.08 | 68 | 264704 | 5360 | 79474256 |
Oedema peripheral | 40.29 | 10.08 | 592 | 264180 | 251696 | 79227920 |
Fracture delayed union | 40.23 | 10.08 | 42 | 264730 | 2068 | 79477548 |
Infection | 40.15 | 10.08 | 1069 | 263703 | 240643 | 79238973 |
Hallucination, visual | 40.07 | 10.08 | 30 | 264742 | 32699 | 79446917 |
Polyneuropathy | 40.05 | 10.08 | 15 | 264757 | 24136 | 79455480 |
Juvenile idiopathic arthritis | 39.90 | 10.08 | 63 | 264709 | 4700 | 79474916 |
Alopecia | 39.82 | 10.08 | 1028 | 263744 | 230327 | 79249289 |
Walking aid user | 39.27 | 10.08 | 97 | 264675 | 10051 | 79469565 |
Dry mouth | 39.17 | 10.08 | 456 | 264316 | 87563 | 79392053 |
Gastrointestinal haemorrhage | 38.85 | 10.08 | 698 | 264074 | 147021 | 79332595 |
Hepatic cytolysis | 38.56 | 10.08 | 21 | 264751 | 27130 | 79452486 |
Product use in unapproved indication | 38.42 | 10.08 | 592 | 264180 | 249767 | 79229849 |
Acute kidney injury | 38.33 | 10.08 | 1375 | 263397 | 518029 | 78961587 |
Intestinal obstruction | 38.31 | 10.08 | 52 | 264720 | 42968 | 79436648 |
Premature delivery | 38.21 | 10.08 | 15 | 264757 | 23452 | 79456164 |
Cerebral infarction | 37.93 | 10.08 | 58 | 264714 | 45618 | 79433998 |
Colitis | 37.86 | 10.08 | 121 | 264651 | 73186 | 79406430 |
Lactic acidosis | 37.85 | 10.08 | 114 | 264658 | 70245 | 79409371 |
Tooth infection | 37.84 | 10.08 | 143 | 264629 | 18689 | 79460927 |
Ankle arthroplasty | 37.73 | 10.08 | 35 | 264737 | 1490 | 79478126 |
Blood creatinine increased | 37.69 | 10.08 | 331 | 264441 | 154726 | 79324890 |
Fall | 37.56 | 10.08 | 1284 | 263488 | 486345 | 78993271 |
Panniculitis | 37.49 | 10.08 | 108 | 264664 | 12263 | 79467353 |
Smear cervix abnormal | 37.18 | 10.08 | 44 | 264728 | 2492 | 79477124 |
Therapeutic response decreased | 37.06 | 10.08 | 362 | 264410 | 66491 | 79413125 |
Subdural haematoma | 36.98 | 10.08 | 30 | 264742 | 31404 | 79448212 |
Urosepsis | 36.90 | 10.08 | 21 | 264751 | 26474 | 79453142 |
Pulmonary fibrosis | 36.86 | 10.08 | 262 | 264510 | 43850 | 79435766 |
Paraesthesia | 36.59 | 10.08 | 804 | 263968 | 175519 | 79304097 |
Iritis | 36.54 | 10.08 | 54 | 264718 | 3801 | 79475815 |
Functional gastrointestinal disorder | 36.39 | 10.08 | 62 | 264710 | 4928 | 79474688 |
Pneumonia aspiration | 36.38 | 10.08 | 108 | 264664 | 66859 | 79412757 |
Pathogen resistance | 36.33 | 10.08 | 3 | 264769 | 14339 | 79465277 |
Gait disturbance | 36.28 | 10.08 | 924 | 263848 | 206582 | 79273034 |
Hyperkalaemia | 36.02 | 10.08 | 227 | 264545 | 114171 | 79365445 |
Pleural effusion | 35.79 | 10.08 | 309 | 264463 | 144953 | 79334663 |
Arthrodesis | 35.68 | 10.08 | 42 | 264730 | 2365 | 79477251 |
Sciatica | 35.53 | 10.08 | 210 | 264562 | 33012 | 79446604 |
Eosinophilia | 35.37 | 10.08 | 60 | 264712 | 45285 | 79434331 |
Sedation complication | 35.32 | 10.08 | 5 | 264767 | 15664 | 79463952 |
Blood pressure decreased | 35.25 | 10.08 | 190 | 264582 | 99276 | 79380340 |
Oesophageal spasm | 35.07 | 10.08 | 50 | 264722 | 3406 | 79476210 |
Status epilepticus | 34.65 | 10.08 | 20 | 264752 | 25021 | 79454595 |
Pseudomonas infection | 34.64 | 10.08 | 13 | 264759 | 20890 | 79458726 |
Schizophrenia | 34.63 | 10.08 | 5 | 264767 | 15435 | 79464181 |
COVID-19 pneumonia | 34.61 | 10.08 | 27 | 264745 | 28822 | 79450794 |
Depressed level of consciousness | 34.60 | 10.08 | 184 | 264588 | 96468 | 79383148 |
Plasma cell myeloma | 34.20 | 10.08 | 79 | 264693 | 53180 | 79426436 |
Device related infection | 34.17 | 10.08 | 38 | 264734 | 34256 | 79445360 |
Diabetes mellitus inadequate control | 34.12 | 10.08 | 19 | 264753 | 24245 | 79455371 |
Circulatory collapse | 34.08 | 10.08 | 45 | 264727 | 37623 | 79441993 |
Milk-alkali syndrome | 34.00 | 10.08 | 32 | 264740 | 1388 | 79478228 |
Limb deformity | 33.61 | 10.08 | 50 | 264722 | 3540 | 79476076 |
Ileus | 33.43 | 10.08 | 23 | 264749 | 26188 | 79453428 |
Photophobia | 33.39 | 10.08 | 146 | 264626 | 20382 | 79459234 |
Sensitivity to weather change | 33.37 | 10.08 | 79 | 264693 | 7968 | 79471648 |
Allergy to chemicals | 33.06 | 10.08 | 42 | 264730 | 2560 | 79477056 |
Blood bilirubin increased | 33.04 | 10.08 | 111 | 264661 | 66121 | 79413495 |
Breast cancer stage III | 32.95 | 10.08 | 89 | 264683 | 9737 | 79469879 |
Creatinine renal clearance decreased | 32.88 | 10.08 | 11 | 264761 | 18991 | 79460625 |
Palmar-plantar erythrodysaesthesia syndrome | 32.71 | 10.08 | 37 | 264735 | 33097 | 79446519 |
Tendon disorder | 32.50 | 10.08 | 73 | 264699 | 7113 | 79472503 |
Intestinal diaphragm disease | 32.49 | 10.08 | 18 | 264754 | 332 | 79479284 |
Pneumocystis jirovecii pneumonia | 32.42 | 10.08 | 36 | 264736 | 32472 | 79447144 |
Gastrointestinal ulcer | 32.27 | 10.08 | 48 | 264724 | 3398 | 79476218 |
Blood lactate dehydrogenase increased | 32.27 | 10.08 | 50 | 264722 | 39120 | 79440496 |
Wrong technique in product usage process | 32.14 | 10.08 | 131 | 264641 | 73744 | 79405872 |
Lymphocyte count decreased | 32.12 | 10.08 | 68 | 264704 | 47221 | 79432395 |
Diplopia | 31.68 | 10.08 | 205 | 264567 | 33261 | 79446355 |
Cytopenia | 31.62 | 10.08 | 14 | 264758 | 20369 | 79459247 |
Haematoma | 31.48 | 10.08 | 80 | 264692 | 52115 | 79427501 |
Pericarditis | 31.20 | 10.08 | 503 | 264269 | 103733 | 79375883 |
Withdrawal arrhythmia | 31.15 | 10.08 | 10 | 264762 | 40 | 79479576 |
Aspartate aminotransferase increased | 31.08 | 10.08 | 302 | 264470 | 138339 | 79341277 |
Hepatocellular injury | 31.04 | 10.08 | 70 | 264702 | 47523 | 79432093 |
Enterococcal infection | 30.96 | 10.08 | 7 | 264765 | 15653 | 79463963 |
Blood alkaline phosphatase increased | 30.88 | 10.08 | 108 | 264664 | 63556 | 79416060 |
Lower respiratory tract infection | 30.66 | 10.08 | 601 | 264171 | 128619 | 79350997 |
Restlessness | 30.63 | 10.08 | 68 | 264704 | 46424 | 79433192 |
Ischaemic stroke | 30.57 | 10.08 | 39 | 264733 | 33092 | 79446524 |
Tumour lysis syndrome | 30.54 | 10.08 | 21 | 264751 | 23918 | 79455698 |
Feeling jittery | 30.49 | 10.08 | 103 | 264669 | 12738 | 79466878 |
Drug level increased | 30.44 | 10.08 | 53 | 264719 | 39598 | 79440018 |
Alanine aminotransferase abnormal | 30.42 | 10.08 | 81 | 264691 | 8786 | 79470830 |
Cardio-respiratory arrest | 30.34 | 10.08 | 223 | 264549 | 108287 | 79371329 |
Lymphopenia | 30.29 | 10.08 | 34 | 264738 | 30523 | 79449093 |
Peptic ulcer | 30.16 | 10.08 | 65 | 264707 | 6158 | 79473458 |
Full blood count decreased | 29.83 | 10.08 | 27 | 264745 | 26792 | 79452824 |
Cholestasis | 29.81 | 10.08 | 82 | 264690 | 52027 | 79427589 |
Metastases to liver | 29.75 | 10.08 | 30 | 264742 | 28284 | 79451332 |
Labelled drug-drug interaction medication error | 29.39 | 10.08 | 29 | 264743 | 27621 | 79451995 |
Disability assessment scale score increased | 29.33 | 10.08 | 46 | 264726 | 3412 | 79476204 |
Uveitis | 29.15 | 10.08 | 122 | 264650 | 16708 | 79462908 |
Cytomegalovirus viraemia | 29.11 | 10.08 | 4 | 264768 | 12817 | 79466799 |
Adverse drug reaction | 29.11 | 10.08 | 343 | 264429 | 66049 | 79413567 |
Left ventricular dysfunction | 28.95 | 10.08 | 14 | 264758 | 19347 | 79460269 |
C-reactive protein | 28.86 | 10.08 | 56 | 264716 | 4923 | 79474693 |
Rhabdomyolysis | 28.81 | 10.08 | 212 | 264560 | 102919 | 79376697 |
Gastritis | 28.65 | 10.08 | 264 | 264508 | 47729 | 79431887 |
Hepatic encephalopathy | 28.51 | 10.08 | 23 | 264749 | 24143 | 79455473 |
Blood pressure systolic increased | 28.46 | 10.08 | 344 | 264428 | 66642 | 79412974 |
Rash papular | 28.44 | 10.08 | 146 | 264626 | 21770 | 79457846 |
Discomfort | 28.39 | 10.08 | 580 | 264192 | 125037 | 79354579 |
Venoocclusive liver disease | 28.38 | 10.08 | 3 | 264769 | 11768 | 79467848 |
Pulmonary oedema | 28.36 | 10.08 | 174 | 264598 | 88080 | 79391536 |
Pancreatitis | 28.35 | 10.08 | 124 | 264648 | 68451 | 79411165 |
Hepatic failure | 28.26 | 10.08 | 106 | 264666 | 61106 | 79418510 |
Gastric disorder | 28.24 | 10.08 | 217 | 264555 | 37216 | 79442400 |
Atrioventricular block complete | 28.08 | 10.08 | 10 | 264762 | 16600 | 79463016 |
Crepitations | 28.02 | 10.08 | 85 | 264687 | 9932 | 79469684 |
Soft tissue injury | 27.95 | 10.08 | 32 | 264740 | 1749 | 79477867 |
Gastroenteritis viral | 27.88 | 10.08 | 159 | 264613 | 24672 | 79454944 |
Cardiac failure acute | 27.83 | 10.08 | 14 | 264758 | 18915 | 79460701 |
Fatigue | 27.57 | 10.08 | 3506 | 261266 | 926221 | 78553395 |
Fixed eruption | 27.46 | 10.08 | 41 | 264731 | 2913 | 79476703 |
Epstein-Barr virus infection | 27.41 | 10.08 | 7 | 264765 | 14409 | 79465207 |
Intentional product use issue | 27.36 | 10.08 | 680 | 264092 | 151432 | 79328184 |
Treatment failure | 27.16 | 10.08 | 750 | 264022 | 169736 | 79309880 |
Oesophageal pain | 27.12 | 10.08 | 50 | 264722 | 4229 | 79475387 |
Serum sickness-like reaction | 27.11 | 10.08 | 20 | 264752 | 615 | 79479001 |
Short stature | 27.10 | 10.08 | 21 | 264751 | 696 | 79478920 |
Malnutrition | 27.07 | 10.08 | 21 | 264751 | 22481 | 79457135 |
Spinal fusion surgery | 26.88 | 10.08 | 56 | 264716 | 5182 | 79474434 |
Cerebrovascular accident | 26.69 | 10.08 | 359 | 264413 | 154933 | 79324683 |
Completed suicide | 26.44 | 10.08 | 1032 | 263740 | 244735 | 79234881 |
Haemorrhage intracranial | 26.13 | 10.08 | 29 | 264743 | 26164 | 79453452 |
Chronic kidney disease | 25.93 | 10.08 | 122 | 264650 | 66032 | 79413584 |
Spondyloarthropathy | 25.89 | 10.08 | 24 | 264748 | 1021 | 79478595 |
Transaminases increased | 25.62 | 10.08 | 87 | 264685 | 51656 | 79427960 |
Pericardial effusion | 25.53 | 10.08 | 74 | 264698 | 46163 | 79433453 |
Unresponsive to stimuli | 25.50 | 10.08 | 97 | 264675 | 55691 | 79423925 |
Deformity | 25.47 | 10.08 | 80 | 264692 | 9525 | 79470091 |
Oedema | 25.35 | 10.08 | 547 | 264225 | 119033 | 79360583 |
Pneumonitis | 25.19 | 10.08 | 110 | 264662 | 60750 | 79418866 |
Vasculitis | 25.15 | 10.08 | 156 | 264616 | 24946 | 79454670 |
Prostate cancer | 25.06 | 10.08 | 45 | 264727 | 33223 | 79446393 |
Antinuclear antibody positive | 25 | 10.08 | 70 | 264702 | 7820 | 79471796 |
Hypophosphataemia | 24.70 | 10.08 | 18 | 264754 | 19895 | 79459721 |
Device ineffective | 24.66 | 10.08 | 12 | 264760 | 167 | 79479449 |
Pemphigoid | 24.59 | 10.08 | 10 | 264762 | 15305 | 79464311 |
Gallbladder injury | 24.53 | 10.08 | 25 | 264747 | 1196 | 79478420 |
Bone density increased | 24.43 | 10.08 | 21 | 264751 | 808 | 79478808 |
Alanine aminotransferase increased | 24.39 | 10.08 | 386 | 264386 | 162184 | 79317432 |
Finger deformity | 24.37 | 10.08 | 67 | 264705 | 7407 | 79472209 |
Skin ulcer | 24.29 | 10.08 | 281 | 264491 | 53869 | 79425747 |
Quality of life decreased | 24.23 | 10.08 | 83 | 264689 | 10337 | 79469279 |
Exposure during pregnancy | 24.08 | 10.08 | 217 | 264555 | 100915 | 79378701 |
Body temperature decreased | 24.06 | 10.08 | 186 | 264586 | 31959 | 79447657 |
Pharyngeal swelling | 23.99 | 10.08 | 68 | 264704 | 7651 | 79471965 |
Disseminated intravascular coagulation | 23.96 | 10.08 | 52 | 264720 | 35790 | 79443826 |
Coma | 23.94 | 10.08 | 216 | 264556 | 100433 | 79379183 |
Kidney infection | 23.94 | 10.08 | 139 | 264633 | 21712 | 79457904 |
Muscular weakness | 23.91 | 10.08 | 701 | 264071 | 160028 | 79319588 |
Skin necrosis | 23.83 | 10.08 | 121 | 264651 | 17966 | 79461650 |
Shock | 23.82 | 10.08 | 70 | 264702 | 43478 | 79436138 |
Aplastic anaemia | 23.80 | 10.08 | 15 | 264757 | 17890 | 79461726 |
Drug level decreased | 23.79 | 10.08 | 9 | 264763 | 14393 | 79465223 |
Synovial disorder | 23.62 | 10.08 | 31 | 264741 | 1952 | 79477664 |
Spinal osteoarthritis | 23.55 | 10.08 | 115 | 264657 | 16812 | 79462804 |
Failure of child resistant product closure | 23.54 | 10.08 | 9 | 264763 | 66 | 79479550 |
Hyperbilirubinaemia | 23.53 | 10.08 | 28 | 264744 | 24490 | 79455126 |
General physical health deterioration | 23.48 | 10.08 | 715 | 264057 | 274523 | 79205093 |
Blindness | 23.38 | 10.08 | 168 | 264604 | 28215 | 79451401 |
Device expulsion | 23.29 | 10.08 | 31 | 264741 | 25830 | 79453786 |
Blood sodium decreased | 23.28 | 10.08 | 47 | 264725 | 33208 | 79446408 |
Dystonia | 23.26 | 10.08 | 22 | 264750 | 21377 | 79458239 |
Cardiotoxicity | 23.16 | 10.08 | 6 | 264766 | 12233 | 79467383 |
Gastritis erosive | 23.16 | 10.08 | 84 | 264688 | 10763 | 79468853 |
Troponin increased | 23.12 | 10.08 | 18 | 264754 | 19237 | 79460379 |
Myoclonus | 23.08 | 10.08 | 35 | 264737 | 27625 | 79451991 |
Clostridium difficile infection | 23.07 | 10.08 | 69 | 264703 | 42616 | 79437000 |
Feeding disorder | 23.02 | 10.08 | 111 | 264661 | 16143 | 79463473 |
Toxic skin eruption | 22.99 | 10.08 | 24 | 264748 | 22269 | 79457347 |
Wheezing | 22.94 | 10.08 | 528 | 264244 | 116136 | 79363480 |
Dementia | 22.78 | 10.08 | 29 | 264743 | 24630 | 79454986 |
Headache | 22.74 | 10.08 | 2491 | 262281 | 651281 | 78828335 |
Dry skin | 22.60 | 10.08 | 334 | 264438 | 67661 | 79411955 |
Vaginal infection | 22.54 | 10.08 | 56 | 264716 | 5824 | 79473792 |
Skin papilloma | 22.50 | 10.08 | 56 | 264716 | 5830 | 79473786 |
Nail psoriasis | 22.46 | 10.08 | 18 | 264754 | 627 | 79478989 |
Inappropriate antidiuretic hormone secretion | 22.24 | 10.08 | 33 | 264739 | 26280 | 79453336 |
Prescribed underdose | 22.21 | 10.08 | 171 | 264601 | 29343 | 79450273 |
Endometriosis | 22.18 | 10.08 | 42 | 264730 | 3626 | 79475990 |
Product dose omission issue | 22.12 | 10.08 | 639 | 264133 | 246898 | 79232718 |
Epistaxis | 22.10 | 10.08 | 250 | 264522 | 111265 | 79368351 |
Failure to thrive | 22.05 | 10.08 | 6 | 264766 | 11838 | 79467778 |
Parkinsonism | 21.89 | 10.08 | 14 | 264758 | 16570 | 79463046 |
Ear infection | 21.88 | 10.08 | 192 | 264580 | 34240 | 79445376 |
Blood potassium decreased | 21.82 | 10.08 | 80 | 264692 | 46432 | 79433184 |
Tendon pain | 21.81 | 10.08 | 54 | 264718 | 5604 | 79474012 |
Aggression | 21.77 | 10.08 | 91 | 264681 | 50867 | 79428749 |
Collagen-vascular disease | 21.66 | 10.08 | 9 | 264763 | 84 | 79479532 |
Immunodeficiency | 21.63 | 10.08 | 135 | 264637 | 21633 | 79457983 |
Depression | 21.62 | 10.08 | 903 | 263869 | 215887 | 79263729 |
Gastroduodenal ulcer | 21.52 | 10.08 | 16 | 264756 | 498 | 79479118 |
Heart rate increased | 21.50 | 10.08 | 539 | 264233 | 120185 | 79359431 |
Progressive multifocal leukoencephalopathy | 21.45 | 10.08 | 22 | 264750 | 20578 | 79459038 |
Anti-glomerular basement membrane disease | 21.36 | 10.08 | 8 | 264764 | 55 | 79479561 |
Sudden death | 21.29 | 10.08 | 26 | 264746 | 22485 | 79457131 |
Joint stiffness | 21.14 | 10.08 | 218 | 264554 | 40612 | 79439004 |
Kounis syndrome | 21.07 | 10.08 | 45 | 264727 | 4237 | 79475379 |
Glossodynia | 21.04 | 10.08 | 470 | 264302 | 102867 | 79376749 |
Blood pressure measurement | 21.00 | 10.08 | 15 | 264757 | 438 | 79479178 |
Hypothyroidism | 20.90 | 10.08 | 96 | 264676 | 52296 | 79427320 |
Chronic obstructive pulmonary disease | 20.90 | 10.08 | 182 | 264590 | 85237 | 79394379 |
Adenoiditis | 20.89 | 10.08 | 7 | 264765 | 33 | 79479583 |
Oxygen saturation decreased | 20.86 | 10.08 | 302 | 264470 | 128745 | 79350871 |
Subarachnoid haemorrhage | 20.84 | 10.08 | 146 | 264626 | 24319 | 79455297 |
Medication overuse headache | 20.79 | 10.08 | 20 | 264752 | 892 | 79478724 |
Appendicitis | 20.76 | 10.08 | 23 | 264749 | 20771 | 79458845 |
Hyperthyroidism | 20.64 | 10.08 | 26 | 264746 | 22183 | 79457433 |
Lower limb fracture | 20.64 | 10.08 | 140 | 264632 | 23075 | 79456541 |
Bradyphrenia | 20.55 | 10.08 | 5 | 264767 | 10635 | 79468981 |
Insomnia | 20.48 | 10.08 | 1003 | 263769 | 244167 | 79235449 |
Extra dose administered | 20.43 | 10.08 | 68 | 264704 | 8347 | 79471269 |
Bronchospasm | 20.22 | 10.08 | 32 | 264740 | 24827 | 79454789 |
Onychomadesis | 20.17 | 10.08 | 50 | 264722 | 5192 | 79474424 |
Urinary tract infection | 20.13 | 10.08 | 727 | 264045 | 273785 | 79205831 |
Rales | 20.11 | 10.08 | 22 | 264750 | 19979 | 79459637 |
Dysphagia | 20.03 | 10.08 | 285 | 264487 | 121851 | 79357765 |
Cachexia | 19.92 | 10.08 | 6 | 264766 | 11077 | 79468539 |
X-ray abnormal | 19.84 | 10.08 | 53 | 264719 | 5760 | 79473856 |
Muscle spasms | 19.80 | 10.08 | 738 | 264034 | 173992 | 79305624 |
Skin fissures | 19.77 | 10.08 | 91 | 264681 | 12982 | 79466634 |
Hepatic enzyme abnormal | 19.75 | 10.08 | 64 | 264708 | 7746 | 79471870 |
Product used for unknown indication | 19.74 | 10.08 | 25 | 264747 | 1519 | 79478097 |
Visual impairment | 19.70 | 10.08 | 422 | 264350 | 91709 | 79387907 |
Human anti-human antibody test | 19.60 | 10.08 | 14 | 264758 | 409 | 79479207 |
Cholangitis | 19.47 | 10.08 | 9 | 264763 | 12767 | 79466849 |
Renal papillary necrosis | 19.39 | 10.08 | 14 | 264758 | 416 | 79479200 |
Product use issue | 19.36 | 10.08 | 867 | 263905 | 208955 | 79270661 |
Hypernatraemia | 19.35 | 10.08 | 12 | 264760 | 14439 | 79465177 |
Jejunal ulcer | 19.33 | 10.08 | 11 | 264761 | 214 | 79479402 |
Diabetic ketoacidosis | 19.29 | 10.08 | 54 | 264718 | 34068 | 79445548 |
Haemoptysis | 19.27 | 10.08 | 108 | 264664 | 55891 | 79423725 |
Bone lesion | 19.24 | 10.08 | 53 | 264719 | 5866 | 79473750 |
Immune reconstitution inflammatory syndrome | 19.23 | 10.08 | 11 | 264761 | 13830 | 79465786 |
Trigger finger | 19.06 | 10.08 | 43 | 264729 | 4202 | 79475414 |
Tachycardia | 19.03 | 10.08 | 447 | 264325 | 177321 | 79302295 |
Anaphylactic reaction | 19.02 | 10.08 | 387 | 264385 | 83356 | 79396260 |
Blood calcium decreased | 19.01 | 10.08 | 49 | 264723 | 31770 | 79447846 |
Hypersensitivity | 18.91 | 10.08 | 1058 | 263714 | 261181 | 79218435 |
Radiation associated pain | 18.90 | 10.08 | 9 | 264763 | 119 | 79479497 |
Altered state of consciousness | 18.88 | 10.08 | 78 | 264694 | 43744 | 79435872 |
Glomerulonephritis membranous | 18.84 | 10.08 | 25 | 264747 | 1591 | 79478025 |
Clear cell renal cell carcinoma | 18.78 | 10.08 | 32 | 264740 | 2544 | 79477072 |
Therapeutic response shortened | 18.76 | 10.08 | 103 | 264669 | 15760 | 79463856 |
Jaundice cholestatic | 18.73 | 10.08 | 7 | 264765 | 11277 | 79468339 |
Product label confusion | 18.72 | 10.08 | 25 | 264747 | 1601 | 79478015 |
Joint noise | 18.68 | 10.08 | 41 | 264731 | 3933 | 79475683 |
Renal mass | 18.67 | 10.08 | 37 | 264735 | 3303 | 79476313 |
Myofascial pain syndrome | 18.54 | 10.08 | 28 | 264744 | 2009 | 79477607 |
Urinary retention | 18.54 | 10.08 | 111 | 264661 | 56519 | 79423097 |
Pneumonia fungal | 18.53 | 10.08 | 7 | 264765 | 11203 | 79468413 |
Haematuria | 18.51 | 10.08 | 143 | 264629 | 68693 | 79410923 |
Hepatic cirrhosis | 18.45 | 10.08 | 57 | 264715 | 34849 | 79444767 |
Anti-transglutaminase antibody | 18.44 | 10.08 | 5 | 264767 | 9 | 79479607 |
Blood pressure systolic abnormal | 18.43 | 10.08 | 109 | 264663 | 17138 | 79462478 |
Mucormycosis | 18.41 | 10.08 | 3 | 264769 | 8466 | 79471150 |
Head injury | 18.38 | 10.08 | 63 | 264709 | 37306 | 79442310 |
Amblyopia | 18.34 | 10.08 | 11 | 264761 | 237 | 79479379 |
Atrioventricular block | 18.34 | 10.08 | 12 | 264760 | 14029 | 79465587 |
Cystitis haemorrhagic | 18.34 | 10.08 | 4 | 264768 | 9168 | 79470448 |
Neutropenic sepsis | 18.31 | 10.08 | 39 | 264733 | 27025 | 79452591 |
Muscle swelling | 18.26 | 10.08 | 18 | 264754 | 827 | 79478789 |
Hyperammonaemia | 18.21 | 10.08 | 7 | 264765 | 11086 | 79468530 |
Anti-cyclic citrullinated peptide antibody positive | 18.16 | 10.08 | 382 | 264390 | 82761 | 79396855 |
Mental status changes | 18.05 | 10.08 | 139 | 264633 | 66820 | 79412796 |
Back injury | 18.00 | 10.08 | 76 | 264696 | 10447 | 79469169 |
Bladder cancer | 18 | 10.08 | 23 | 264749 | 19503 | 79460113 |
Drug reaction with eosinophilia and systemic symptoms | 17.97 | 10.08 | 132 | 264640 | 64112 | 79415504 |
Post-traumatic neck syndrome | 17.96 | 10.08 | 28 | 264744 | 2066 | 79477550 |
Tachypnoea | 17.93 | 10.08 | 51 | 264721 | 32012 | 79447604 |
Balance disorder | 17.91 | 10.08 | 226 | 264546 | 98631 | 79380985 |
Hepatocellular carcinoma | 17.90 | 10.08 | 4 | 264768 | 9017 | 79470599 |
Metastases to fallopian tube | 17.89 | 10.08 | 7 | 264765 | 55 | 79479561 |
Sternal fracture | 17.88 | 10.08 | 31 | 264741 | 2499 | 79477117 |
Flank pain | 17.84 | 10.08 | 120 | 264652 | 19724 | 79459892 |
Lipase increased | 17.82 | 10.08 | 17 | 264755 | 16449 | 79463167 |
Biliary dyskinesia | 17.75 | 10.08 | 31 | 264741 | 2514 | 79477102 |
Myocarditis | 17.66 | 10.08 | 28 | 264744 | 21705 | 79457911 |
Chronic spontaneous urticaria | 17.55 | 10.08 | 21 | 264751 | 1203 | 79478413 |
Metastases to bone | 17.55 | 10.08 | 34 | 264738 | 24393 | 79455223 |
Sleep disorder | 17.54 | 10.08 | 390 | 264382 | 85287 | 79394329 |
Hepatic adenoma | 17.49 | 10.08 | 12 | 264760 | 328 | 79479288 |
Glomerulonephritis minimal lesion | 17.45 | 10.08 | 17 | 264755 | 770 | 79478846 |
Sinus bradycardia | 17.40 | 10.08 | 36 | 264736 | 25211 | 79454405 |
Ventricular arrhythmia | 17.38 | 10.08 | 4 | 264768 | 8836 | 79470780 |
Malignant melanoma in situ | 17.27 | 10.08 | 30 | 264742 | 2422 | 79477194 |
Aphasia | 17.26 | 10.08 | 88 | 264684 | 46644 | 79432972 |
Nail dystrophy | 17.26 | 10.08 | 19 | 264753 | 994 | 79478622 |
Limb asymmetry | 17.25 | 10.08 | 15 | 264757 | 586 | 79479030 |
Myopathy | 17.18 | 10.08 | 26 | 264746 | 20537 | 79459079 |
Abnormal loss of weight | 17.16 | 10.08 | 64 | 264708 | 8312 | 79471304 |
Red cell distribution width decreased | 17.13 | 10.08 | 27 | 264745 | 2011 | 79477605 |
Lip oedema | 17.11 | 10.08 | 53 | 264719 | 6263 | 79473353 |
Decreased appetite | 17.08 | 10.08 | 946 | 263826 | 341472 | 79138144 |
Adverse event | 17.06 | 10.08 | 288 | 264484 | 59926 | 79419690 |
Fluid retention | 16.96 | 10.08 | 149 | 264623 | 69660 | 79409956 |
Swollen tongue | 16.96 | 10.08 | 216 | 264556 | 42354 | 79437262 |
Blood pressure diastolic increased | 16.91 | 10.08 | 94 | 264678 | 14448 | 79465168 |
Respiratory acidosis | 16.90 | 10.08 | 8 | 264764 | 11192 | 79468424 |
Inflammatory pain | 16.84 | 10.08 | 19 | 264753 | 1022 | 79478594 |
Tardive dyskinesia | 16.81 | 10.08 | 7 | 264765 | 10564 | 79469052 |
Heart rate | 16.79 | 10.08 | 8 | 264764 | 106 | 79479510 |
No adverse event | 16.78 | 10.08 | 65 | 264707 | 37127 | 79442489 |
Dialysis | 16.76 | 10.08 | 22 | 264750 | 18440 | 79461176 |
COVID-19 | 16.72 | 10.08 | 397 | 264375 | 157277 | 79322339 |
Hypertensive crisis | 16.65 | 10.08 | 27 | 264745 | 20743 | 79458873 |
Blood pressure diastolic abnormal | 16.60 | 10.08 | 115 | 264657 | 19087 | 79460529 |
Renal cancer | 16.59 | 10.08 | 10 | 264762 | 12216 | 79467400 |
Ejection fraction decreased | 16.54 | 10.08 | 59 | 264713 | 34518 | 79445098 |
Musculoskeletal deformity | 16.51 | 10.08 | 23 | 264749 | 1533 | 79478083 |
Hallucination, auditory | 16.49 | 10.08 | 27 | 264745 | 20666 | 79458950 |
Candida infection | 16.47 | 10.08 | 68 | 264704 | 38146 | 79441470 |
Endocarditis fibroplastica | 16.43 | 10.08 | 5 | 264767 | 16 | 79479600 |
Haemolytic anaemia | 16.42 | 10.08 | 21 | 264751 | 17799 | 79461817 |
Disease recurrence | 16.33 | 10.08 | 83 | 264689 | 44026 | 79435590 |
Urinary incontinence | 16.29 | 10.08 | 75 | 264697 | 40834 | 79438782 |
Intentional overdose | 16.26 | 10.08 | 464 | 264308 | 105496 | 79374120 |
Periorbital oedema | 16.22 | 10.08 | 63 | 264709 | 8339 | 79471277 |
Coagulopathy | 16.20 | 10.08 | 63 | 264709 | 35943 | 79443673 |
Staphylococcal infection | 16.20 | 10.08 | 120 | 264652 | 58175 | 79421441 |
Rheumatoid factor positive | 16.16 | 10.08 | 284 | 264488 | 59555 | 79420061 |
Aspirin-exacerbated respiratory disease | 16.16 | 10.08 | 20 | 264752 | 1187 | 79478429 |
Blood bilirubin unconjugated | 16.09 | 10.08 | 4 | 264768 | 4 | 79479612 |
Heparin-induced thrombocytopenia | 16.08 | 10.08 | 6 | 264766 | 9676 | 79469940 |
Pulseless electrical activity | 16.06 | 10.08 | 14 | 264758 | 14146 | 79465470 |
Generalised tonic-clonic seizure | 16.04 | 10.08 | 83 | 264689 | 43827 | 79435789 |
Vascular device infection | 16.03 | 10.08 | 7 | 264765 | 10269 | 79469347 |
Device leakage | 16.00 | 10.08 | 8 | 264764 | 10848 | 79468768 |
Therapy interrupted | 15.99 | 10.08 | 52 | 264720 | 31289 | 79448327 |
Transfusion | 15.93 | 10.08 | 29 | 264743 | 21301 | 79458315 |
Cardiomyopathy | 15.92 | 10.08 | 46 | 264726 | 28728 | 79450888 |
Gastrointestinal fistula | 15.92 | 10.08 | 16 | 264756 | 753 | 79478863 |
Road traffic accident | 15.91 | 10.08 | 218 | 264554 | 43446 | 79436170 |
Left ventricular failure | 15.80 | 10.08 | 6 | 264766 | 9575 | 79470041 |
Helicobacter infection | 15.79 | 10.08 | 322 | 264450 | 69382 | 79410234 |
Gastrointestinal disorder | 15.79 | 10.08 | 524 | 264248 | 121681 | 79357935 |
Hypercapnia | 15.77 | 10.08 | 5 | 264767 | 8930 | 79470686 |
Peripheral arterial occlusive disease | 15.72 | 10.08 | 4 | 264768 | 8254 | 79471362 |
Product monitoring error | 15.69 | 10.08 | 5 | 264767 | 8901 | 79470715 |
Enterocolitis | 15.68 | 10.08 | 15 | 264757 | 14497 | 79465119 |
Incorrect dosage administered | 15.64 | 10.08 | 31 | 264741 | 2768 | 79476848 |
IIIrd nerve injury | 15.62 | 10.08 | 4 | 264768 | 5 | 79479611 |
Pneumonia bacterial | 15.62 | 10.08 | 25 | 264747 | 19306 | 79460310 |
Bacterial sepsis | 15.55 | 10.08 | 4 | 264768 | 8194 | 79471422 |
Acute coronary syndrome | 15.55 | 10.08 | 29 | 264743 | 21104 | 79458512 |
Hyperuricaemia | 15.52 | 10.08 | 10 | 264762 | 11789 | 79467827 |
Brain herniation | 15.45 | 10.08 | 3 | 264769 | 7460 | 79472156 |
Stress cardiomyopathy | 15.33 | 10.08 | 9 | 264763 | 11157 | 79468459 |
Second primary malignancy | 15.31 | 10.08 | 15 | 264757 | 14335 | 79465281 |
Nightmare | 15.30 | 10.08 | 142 | 264630 | 25719 | 79453897 |
Staphylococcal bacteraemia | 15.21 | 10.08 | 11 | 264761 | 12207 | 79467409 |
Toxicity to various agents | 15.20 | 10.08 | 1199 | 263573 | 420341 | 79059275 |
Anal incontinence | 15.15 | 10.08 | 23 | 264749 | 18145 | 79461471 |
Metastases to lung | 15.14 | 10.08 | 23 | 264749 | 18140 | 79461476 |
Eye pain | 15.11 | 10.08 | 191 | 264581 | 37387 | 79442229 |
Eye irritation | 15.11 | 10.08 | 119 | 264653 | 20562 | 79459054 |
Hypoalbuminaemia | 14.99 | 10.08 | 30 | 264742 | 21267 | 79458349 |
Adverse reaction | 14.96 | 10.08 | 66 | 264706 | 9248 | 79470368 |
Eosinophil count increased | 14.90 | 10.08 | 21 | 264751 | 17084 | 79462532 |
Gastric ulcer perforation | 14.88 | 10.08 | 26 | 264746 | 2109 | 79477507 |
Rash maculo-papular | 14.84 | 10.08 | 117 | 264655 | 55961 | 79423655 |
Cushingoid | 14.83 | 10.08 | 67 | 264705 | 9485 | 79470131 |
Vaginal stricture | 14.82 | 10.08 | 4 | 264768 | 7 | 79479609 |
Somnolence | 14.69 | 10.08 | 646 | 264126 | 238335 | 79241281 |
Hostility | 14.65 | 10.08 | 27 | 264745 | 2283 | 79477333 |
Glaucoma | 14.64 | 10.08 | 27 | 264745 | 19734 | 79459882 |
Palpitations | 14.64 | 10.08 | 536 | 264236 | 126074 | 79353542 |
Chronic sinusitis | 14.63 | 10.08 | 13 | 264759 | 13013 | 79466603 |
Peptic ulcer perforation | 14.43 | 10.08 | 12 | 264760 | 441 | 79479175 |
Hyperhidrosis | 14.42 | 10.08 | 628 | 264144 | 150864 | 79328752 |
Mania | 14.39 | 10.08 | 24 | 264748 | 18236 | 79461380 |
Disorientation | 14.38 | 10.08 | 136 | 264636 | 62640 | 79416976 |
Device occlusion | 14.37 | 10.08 | 11 | 264761 | 11855 | 79467761 |
Normal newborn | 14.31 | 10.08 | 3 | 264769 | 7069 | 79472547 |
Infective pulmonary exacerbation of cystic fibrosis | 14.22 | 10.08 | 13 | 264759 | 12838 | 79466778 |
Neutrophil count increased | 14.16 | 10.08 | 50 | 264722 | 29346 | 79450270 |
Haemolysis | 14.13 | 10.08 | 13 | 264759 | 12799 | 79466817 |
Penile swelling | 14.05 | 10.08 | 14 | 264758 | 652 | 79478964 |
Asphyxia | 14.02 | 10.08 | 11 | 264761 | 11709 | 79467907 |
Intestinal ischaemia | 14.01 | 10.08 | 14 | 264758 | 13256 | 79466360 |
Klebsiella infection | 14.00 | 10.08 | 19 | 264753 | 15701 | 79463915 |
Tachyarrhythmia | 13.99 | 10.08 | 3 | 264769 | 6959 | 79472657 |
Akathisia | 13.99 | 10.08 | 14 | 264758 | 13245 | 79466371 |
Brain natriuretic peptide increased | 13.99 | 10.08 | 6 | 264766 | 8894 | 79470722 |
End stage renal disease | 13.96 | 10.08 | 12 | 264760 | 12208 | 79467408 |
Acute biphenotypic leukaemia | 13.95 | 10.08 | 8 | 264764 | 158 | 79479458 |
Endocarditis | 13.92 | 10.08 | 9 | 264763 | 10588 | 79469028 |
Escherichia infection | 13.90 | 10.08 | 24 | 264748 | 17993 | 79461623 |
Hiccups | 13.90 | 10.08 | 8 | 264764 | 10023 | 79469593 |
Diverticulitis | 13.86 | 10.08 | 222 | 264550 | 45714 | 79433902 |
Hypomania | 13.71 | 10.08 | 4 | 264768 | 7540 | 79472076 |
Nail bed bleeding | 13.70 | 10.08 | 14 | 264758 | 672 | 79478944 |
Ventricular extrasystoles | 13.66 | 10.08 | 28 | 264744 | 19676 | 79459940 |
Colitis ulcerative | 13.65 | 10.08 | 64 | 264708 | 34678 | 79444938 |
Faecaloma | 13.65 | 10.08 | 11 | 264761 | 11553 | 79468063 |
Fine motor skill dysfunction | 13.64 | 10.08 | 44 | 264728 | 5313 | 79474303 |
Systemic lupus erythematosus | 13.55 | 10.08 | 511 | 264261 | 120638 | 79358978 |
Brain oedema | 13.54 | 10.08 | 41 | 264731 | 25222 | 79454394 |
Drug eruption | 13.51 | 10.08 | 213 | 264559 | 43722 | 79435894 |
Caesarean section | 13.49 | 10.08 | 13 | 264759 | 12522 | 79467094 |
Chills | 13.47 | 10.08 | 417 | 264355 | 159817 | 79319799 |
Meningitis streptococcal | 13.43 | 10.08 | 8 | 264764 | 170 | 79479446 |
Organising pneumonia | 13.42 | 10.08 | 10 | 264762 | 10929 | 79468687 |
Full blood count abnormal | 13.42 | 10.08 | 79 | 264693 | 40395 | 79439221 |
Acquired cystic kidney disease | 13.42 | 10.08 | 6 | 264766 | 68 | 79479548 |
Ocular hyperaemia | 13.39 | 10.08 | 148 | 264624 | 28058 | 79451558 |
Colorectal cancer | 13.32 | 10.08 | 6 | 264766 | 8641 | 79470975 |
Vaginal abscess | 13.30 | 10.08 | 11 | 264761 | 401 | 79479215 |
Hypogammaglobulinaemia | 13.29 | 10.08 | 14 | 264758 | 12937 | 79466679 |
Bacterial infection | 13.27 | 10.08 | 56 | 264716 | 31224 | 79448392 |
Drug level below therapeutic | 13.24 | 10.08 | 8 | 264764 | 9762 | 79469854 |
Breast cancer stage I | 13.24 | 10.08 | 3 | 264769 | 6697 | 79472919 |
Blood pressure fluctuation | 13.23 | 10.08 | 304 | 264468 | 66841 | 79412775 |
Joint ankylosis | 13.23 | 10.08 | 25 | 264747 | 2155 | 79477461 |
Syndesmophyte | 13.19 | 10.08 | 6 | 264766 | 71 | 79479545 |
Metabolic disorder | 13.16 | 10.08 | 7 | 264765 | 9163 | 79470453 |
Splenomegaly | 13.15 | 10.08 | 31 | 264741 | 20723 | 79458893 |
Lung infiltration | 13.14 | 10.08 | 36 | 264736 | 22876 | 79456740 |
Metabolic encephalopathy | 13.10 | 10.08 | 7 | 264765 | 9140 | 79470476 |
Neutrophilia | 13.08 | 10.08 | 5 | 264767 | 7946 | 79471670 |
Eosinophilic pneumonia | 12.97 | 10.08 | 43 | 264729 | 5267 | 79474349 |
Back disorder | 12.91 | 10.08 | 74 | 264698 | 11504 | 79468112 |
Acute myocardial infarction | 12.90 | 10.08 | 179 | 264593 | 76857 | 79402759 |
Complication associated with device | 12.88 | 10.08 | 24 | 264748 | 17472 | 79462144 |
Aspiration | 12.86 | 10.08 | 30 | 264742 | 20128 | 79459488 |
Hypertonia | 12.84 | 10.08 | 4 | 264768 | 7228 | 79472388 |
Blood urea increased | 12.82 | 10.08 | 102 | 264670 | 48688 | 79430928 |
Goitre | 12.78 | 10.08 | 44 | 264728 | 5495 | 79474121 |
Abdominal distension | 12.76 | 10.08 | 301 | 264471 | 119349 | 79360267 |
Hodgkin's disease | 12.74 | 10.08 | 15 | 264757 | 845 | 79478771 |
Allodynia | 12.72 | 10.08 | 21 | 264751 | 1627 | 79477989 |
Taste disorder | 12.65 | 10.08 | 93 | 264679 | 15730 | 79463886 |
Premature labour | 12.65 | 10.08 | 6 | 264766 | 8384 | 79471232 |
Diffuse large B-cell lymphoma | 12.62 | 10.08 | 13 | 264759 | 12136 | 79467480 |
Spinal pain | 12.61 | 10.08 | 91 | 264681 | 15301 | 79464315 |
Endometrial cancer stage I | 12.61 | 10.08 | 8 | 264764 | 191 | 79479425 |
Pemphigus | 12.61 | 10.08 | 426 | 264346 | 99156 | 79380460 |
Oral candidiasis | 12.60 | 10.08 | 53 | 264719 | 29575 | 79450041 |
Lipidosis | 12.60 | 10.08 | 5 | 264767 | 41 | 79479575 |
Atelectasis | 12.56 | 10.08 | 163 | 264609 | 32094 | 79447522 |
Nephropathy toxic | 12.54 | 10.08 | 31 | 264741 | 20388 | 79459228 |
Supraventricular tachycardia | 12.52 | 10.08 | 33 | 264739 | 21237 | 79458379 |
Multiple sclerosis | 12.51 | 10.08 | 121 | 264651 | 22161 | 79457455 |
Limb operation | 12.47 | 10.08 | 32 | 264740 | 3394 | 79476222 |
Pneumothorax | 12.46 | 10.08 | 50 | 264722 | 28273 | 79451343 |
Duodenitis | 12.45 | 10.08 | 56 | 264716 | 7911 | 79471705 |
Pancreatitis acute | 12.44 | 10.08 | 105 | 264667 | 49499 | 79430117 |
Pneumatosis intestinalis | 12.37 | 10.08 | 3 | 264769 | 6394 | 79473222 |
Pre-eclampsia | 12.32 | 10.08 | 4 | 264768 | 7037 | 79472579 |
Nerve compression | 12.31 | 10.08 | 62 | 264710 | 9177 | 79470439 |
Mean cell haemoglobin decreased | 12.29 | 10.08 | 47 | 264725 | 6177 | 79473439 |
Accidental overdose | 12.22 | 10.08 | 79 | 264693 | 39502 | 79440114 |
Venous angioma of brain | 12.19 | 10.08 | 5 | 264767 | 45 | 79479571 |
Granulocytopenia | 12.14 | 10.08 | 12 | 264760 | 11419 | 79468197 |
Diabetes mellitus | 12.13 | 10.08 | 185 | 264587 | 78205 | 79401411 |
Therapy cessation | 12.10 | 10.08 | 74 | 264698 | 37488 | 79442128 |
Hepatitis cholestatic | 12.07 | 10.08 | 17 | 264755 | 13835 | 79465781 |
Injection site reaction | 12.05 | 10.08 | 252 | 264520 | 54533 | 79425083 |
Cardiac disorder | 12.03 | 10.08 | 150 | 264622 | 65607 | 79414009 |
Ventricular hypokinesia | 12.02 | 10.08 | 8 | 264764 | 9271 | 79470345 |
Glycosylated haemoglobin increased | 12.02 | 10.08 | 29 | 264743 | 19231 | 79460385 |
Dermatitis exfoliative | 11.93 | 10.08 | 11 | 264761 | 10818 | 79468798 |
Haemorrhage | 11.83 | 10.08 | 222 | 264550 | 90896 | 79388720 |
Polymenorrhagia | 11.82 | 10.08 | 5 | 264767 | 49 | 79479567 |
Adrenergic syndrome | 11.79 | 10.08 | 7 | 264765 | 148 | 79479468 |
Congenital bowing of long bones | 11.74 | 10.08 | 4 | 264768 | 20 | 79479596 |
Pseudomonal sepsis | 11.74 | 10.08 | 3 | 264769 | 6171 | 79473445 |
Dysarthria | 11.73 | 10.08 | 156 | 264616 | 67466 | 79412150 |
Enteritis | 11.65 | 10.08 | 19 | 264753 | 14564 | 79465052 |
Helicobacter test positive | 11.63 | 10.08 | 18 | 264754 | 1320 | 79478296 |
Cerebral ischaemia | 11.60 | 10.08 | 12 | 264760 | 11183 | 79468433 |
Condition aggravated | 11.54 | 10.08 | 1863 | 262909 | 499261 | 78980355 |
Exercise tolerance decreased | 11.51 | 10.08 | 8 | 264764 | 9063 | 79470553 |
Hyperpyrexia | 11.50 | 10.08 | 3 | 264769 | 6089 | 79473527 |
Escherichia sepsis | 11.48 | 10.08 | 7 | 264765 | 8501 | 79471115 |
Hypothermia | 11.43 | 10.08 | 38 | 264734 | 22708 | 79456908 |
Coronary arterial stent insertion | 11.37 | 10.08 | 3 | 264769 | 6041 | 79473575 |
Cyanosis | 11.37 | 10.08 | 44 | 264728 | 25138 | 79454478 |
Device malfunction | 11.35 | 10.08 | 35 | 264737 | 21413 | 79458203 |
Small intestinal haemorrhage | 11.34 | 10.08 | 35 | 264737 | 4128 | 79475488 |
Tendon rupture | 11.31 | 10.08 | 74 | 264698 | 12052 | 79467564 |
Disturbance in attention | 11.28 | 10.08 | 234 | 264538 | 50567 | 79429049 |
Frequent bowel movements | 11.27 | 10.08 | 55 | 264717 | 29484 | 79450132 |
Unevaluable event | 11.25 | 10.08 | 124 | 264648 | 55461 | 79424155 |
Intervertebral disc protrusion | 11.24 | 10.08 | 124 | 264648 | 23497 | 79456119 |
Substance abuse | 11.23 | 10.08 | 11 | 264761 | 10515 | 79469101 |
Tremor | 11.23 | 10.08 | 456 | 264316 | 169627 | 79309989 |
Sputum discoloured | 11.21 | 10.08 | 116 | 264656 | 21627 | 79457989 |
Chronic pigmented purpura | 11.19 | 10.08 | 8 | 264764 | 234 | 79479382 |
Autoimmune haemolytic anaemia | 11.17 | 10.08 | 7 | 264765 | 8373 | 79471243 |
Mean platelet volume decreased | 11.15 | 10.08 | 27 | 264745 | 2763 | 79476853 |
Lip and/or oral cavity cancer | 11.14 | 10.08 | 16 | 264756 | 1097 | 79478519 |
Polydipsia | 11.13 | 10.08 | 4 | 264768 | 6601 | 79473015 |
Staphylococcal sepsis | 11.02 | 10.08 | 20 | 264752 | 14706 | 79464910 |
Renal arteriosclerosis | 11.00 | 10.08 | 9 | 264763 | 323 | 79479293 |
Haematocrit decreased | 10.99 | 10.08 | 274 | 264498 | 61038 | 79418578 |
Libido increased | 10.99 | 10.08 | 22 | 264750 | 1979 | 79477637 |
White blood cell count increased | 10.92 | 10.08 | 178 | 264594 | 74455 | 79405161 |
Therapeutic product effect incomplete | 10.90 | 10.08 | 575 | 264197 | 141070 | 79338546 |
Blood potassium increased | 10.89 | 10.08 | 55 | 264717 | 29220 | 79450396 |
Nail disorder | 10.85 | 10.08 | 72 | 264700 | 11780 | 79467836 |
Gynaecomastia | 10.82 | 10.08 | 6 | 264766 | 7675 | 79471941 |
Vascular access complication | 10.82 | 10.08 | 23 | 264749 | 2159 | 79477457 |
Gallbladder cholesterolosis | 10.81 | 10.08 | 12 | 264760 | 634 | 79478982 |
Jaundice | 10.80 | 10.08 | 119 | 264653 | 53230 | 79426386 |
Cervicobrachial syndrome | 10.79 | 10.08 | 16 | 264756 | 1130 | 79478486 |
Retinal haemorrhage | 10.76 | 10.08 | 7 | 264765 | 8210 | 79471406 |
Asthenia | 10.75 | 10.08 | 1512 | 263260 | 510177 | 78969439 |
Metastases to central nervous system | 10.75 | 10.08 | 24 | 264748 | 16351 | 79463265 |
Obstructive pancreatitis | 10.73 | 10.08 | 14 | 264758 | 876 | 79478740 |
Foetal exposure during pregnancy | 10.65 | 10.08 | 3 | 264769 | 5787 | 79473829 |
Mouth ulceration | 10.65 | 10.08 | 183 | 264589 | 38211 | 79441405 |
Nausea | 10.63 | 10.08 | 3440 | 261332 | 953756 | 78525860 |
Granuloma | 10.58 | 10.08 | 55 | 264717 | 8242 | 79471374 |
Hemiplegia | 10.55 | 10.08 | 21 | 264751 | 14918 | 79464698 |
Serotonin syndrome | 10.55 | 10.08 | 97 | 264675 | 44930 | 79434686 |
Amylase increased | 10.54 | 10.08 | 13 | 264759 | 11196 | 79468420 |
Alcoholic hangover | 10.54 | 10.08 | 3 | 264769 | 7 | 79479609 |
Intervertebral disc degeneration | 10.54 | 10.08 | 89 | 264683 | 15696 | 79463920 |
Tender joint count decreased | 10.51 | 10.08 | 7 | 264765 | 182 | 79479434 |
Occult blood positive | 10.48 | 10.08 | 48 | 264724 | 6835 | 79472781 |
Swollen joint count decreased | 10.44 | 10.08 | 7 | 264765 | 184 | 79479432 |
Tandem gait test abnormal | 10.44 | 10.08 | 5 | 264767 | 67 | 79479549 |
Endodontic procedure | 10.38 | 10.08 | 26 | 264746 | 2717 | 79476899 |
Uterine perforation | 10.38 | 10.08 | 45 | 264727 | 6258 | 79473358 |
Allergic respiratory disease | 10.35 | 10.08 | 6 | 264766 | 121 | 79479495 |
Foetal death | 10.34 | 10.08 | 7 | 264765 | 8037 | 79471579 |
Decubitus ulcer | 10.29 | 10.08 | 23 | 264749 | 15664 | 79463952 |
Small intestinal obstruction | 10.28 | 10.08 | 51 | 264721 | 27221 | 79452395 |
Stupor | 10.23 | 10.08 | 5 | 264767 | 6867 | 79472749 |
Pulmonary congestion | 10.16 | 10.08 | 136 | 264636 | 26964 | 79452652 |
Oesophageal ulcer | 10.14 | 10.08 | 48 | 264724 | 6927 | 79472689 |
Device related sepsis | 10.14 | 10.08 | 4 | 264768 | 6236 | 79473380 |
Oral pustule | 10.12 | 10.08 | 8 | 264764 | 273 | 79479343 |
Concussion | 10.12 | 10.08 | 60 | 264712 | 9443 | 79470173 |
None
Source | Code | Description |
---|---|---|
ATC | G02CC02 | GENITO URINARY SYSTEM AND SEX HORMONES OTHER GYNECOLOGICALS OTHER GYNECOLOGICALS Antiinflammatory products for vaginal administration |
ATC | M01AE02 | MUSCULO-SKELETAL SYSTEM ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS Propionic acid derivatives |
ATC | M01AE52 | MUSCULO-SKELETAL SYSTEM ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS Propionic acid derivatives |
ATC | M01AE56 | MUSCULO-SKELETAL SYSTEM ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS Propionic acid derivatives |
ATC | M02AA12 | MUSCULO-SKELETAL SYSTEM TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN Antiinflammatory preparations, non-steroids for topical use |
FDA CS | M0001335 | Anti-Inflammatory Agents, Non-Steroidal |
FDA MoA | N0000000160 | Cyclooxygenase Inhibitors |
MeSH PA | D000700 | Analgesics |
MeSH PA | D018712 | Analgesics, Non-Narcotic |
MeSH PA | D000893 | Anti-Inflammatory Agents |
MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
MeSH PA | D018501 | Antirheumatic Agents |
MeSH PA | D016861 | Cyclooxygenase Inhibitors |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D006074 | Gout Suppressants |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D018689 | Sensory System Agents |
CHEBI has role | CHEBI:35475 | non-steroidal anti-inflammatory agent |
CHEBI has role | CHEBI:35493 | anti-pyretic |
CHEBI has role | CHEBI:35703 | Xenobiotic |
CHEBI has role | CHEBI:35845 | gout suppressants |
CHEBI has role | CHEBI:50629 | COX-2 inhibitor |
CHEBI has role | CHEBI:50630 | COX-1 inhibitor |
CHEBI has role | CHEBI:78298 | environmental contaminants |
CHEBI has role | CHEBI:88188 | allergenic drug |
FDA EPC | N0000175722 | Nonsteroidal Anti-inflammatory Drug |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Sinus headache | indication | 4969004 | |
Ankylosing spondylitis | indication | 9631008 | DOID:7147 |
Pain | indication | 22253000 | |
Toothache | indication | 27355003 | |
Tendinitis | indication | 34840004 | DOID:971 |
Migraine | indication | 37796009 | DOID:6364 |
Joint pain | indication | 57676002 | |
Nasal discharge | indication | 64531003 | |
Muscle pain | indication | 68962001 | |
Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
Bursitis | indication | 84017003 | DOID:2965 |
Gout | indication | 90560007 | DOID:13189 |
Headache disorder | indication | 230461009 | |
Dysmenorrhea | indication | 266599000 | |
Fever | indication | 386661006 | |
Osteoarthritis | indication | 396275006 | |
Juvenile rheumatoid arthritis | indication | 410795001 | |
Tachyarrhythmia | contraindication | 6285003 | |
Alcoholism | contraindication | 7200002 | |
Hypercholesterolemia | contraindication | 13644009 | |
Myocardial infarction | contraindication | 22298006 | DOID:5844 |
Hypovolemia | contraindication | 28560003 | |
Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Gastrointestinal ulcer | contraindication | 40845000 | |
Body fluid retention | contraindication | 43498006 | |
Chronic heart failure | contraindication | 48447003 | |
Disorder of cardiovascular system | contraindication | 49601007 | DOID:1287 |
Gastrointestinal perforation | contraindication | 51875005 | |
Coronary arteriosclerosis | contraindication | 53741008 | DOID:3393 |
Hemiplegic migraine | contraindication | 59292006 | |
Hepatic failure | contraindication | 59927004 | |
Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
Osteoporosis | contraindication | 64859006 | DOID:11476 |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Gastrointestinal hemorrhage | contraindication | 74474003 | |
Vascular insufficiency of intestine | contraindication | 82196007 | |
Atrophic gastritis | contraindication | 84568007 | DOID:8929 |
Epilepsy | contraindication | 84757009 | DOID:1826 |
Prinzmetal angina | contraindication | 87343002 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Fracture of bone | contraindication | 125605004 | |
Liver function tests abnormal | contraindication | 166603001 | |
Hypomagnesemia | contraindication | 190855004 | |
Angina pectoris | contraindication | 194828000 | |
Cerebrovascular accident | contraindication | 230690007 | |
Coronary artery bypass graft | contraindication | 232717009 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Transient ischemic attack | contraindication | 266257000 | DOID:224 |
Esophageal dysmotility | contraindication | 266434009 | DOID:9192 |
Benign prostatic hyperplasia | contraindication | 266569009 | |
Edema | contraindication | 267038008 | |
Retention of urine | contraindication | 267064002 | |
Anemia | contraindication | 271737000 | DOID:2355 |
Cerebral ischemia | contraindication | 287731003 | |
Pregnancy, function | contraindication | 289908002 | |
Thromboembolic disorder | contraindication | 371039008 | |
Serotonin syndrome | contraindication | 371089000 | |
Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
Cardiovascular event risk | contraindication | 395112001 | |
Peripheral vascular disease | contraindication | 400047006 | |
Disorder of coronary artery | contraindication | 414024009 | |
Myocardial ischemia | contraindication | 414795007 | DOID:3393 |
Obesity | contraindication | 414916001 | DOID:9970 |
Hypertensive urgency | contraindication | 443482000 | |
Smokes tobacco daily | contraindication | 449868002 |
Species | Use | Relation |
---|---|---|
Horses | Myositis | Indication |
Horses | Pain and inflammation associated with arthritis | Indication |
Horses | Soft tissue diseases of the musculoskeletal system | Indication |
Product | Applicant | Ingredients |
---|---|---|
Equiproxen Granules | Zoetis Inc. | 1 |
Equiproxen 10% Solution | Zoetis Inc. | 1 |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.36 | acidic |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
500MG;EQ 85MG BASE | TREXIMET | CURRAX | N021926 | April 15, 2008 | RX | TABLET | ORAL | 7332183 | Oct. 2, 2025 | TREATMENT OF MIGRAINE |
60MG;EQ 10MG BASE | TREXIMET | CURRAX | N021926 | May 14, 2015 | DISCN | TABLET | ORAL | 7332183 | Oct. 2, 2025 | ACUTE TREATMENT OF MIGRAINE |
EQ 200MG BASE | NAPROXEN SODIUM | BIONPHARMA | N021920 | Feb. 17, 2006 | OTC | CAPSULE | ORAL | 10022344 | March 3, 2026 | TEMPORARY REDUCTION OF FEVER |
EQ 200MG BASE | NAPROXEN SODIUM | BIONPHARMA | N021920 | Feb. 17, 2006 | OTC | CAPSULE | ORAL | 10022344 | March 3, 2026 | TEMPORARY RELIEF OF MINOR ACHES AND PAINS |
EQ 200MG BASE | NAPROXEN SODIUM | BIONPHARMA | N021920 | Feb. 17, 2006 | OTC | CAPSULE | ORAL | 10028925 | March 3, 2026 | TEMPORARY REDUCTION OF FEVER |
EQ 200MG BASE | NAPROXEN SODIUM | BIONPHARMA | N021920 | Feb. 17, 2006 | OTC | CAPSULE | ORAL | 10028925 | March 3, 2026 | TEMPORARY RELIEF OF MINOR ACHES AND PAINS |
EQ 200MG BASE | NAPROXEN SODIUM | BIONPHARMA | N021920 | Feb. 17, 2006 | OTC | CAPSULE | ORAL | 11090280 | March 3, 2026 | TEMPORARY REDUCTION OF FEVER |
EQ 200MG BASE | NAPROXEN SODIUM | BIONPHARMA | N021920 | Feb. 17, 2006 | OTC | CAPSULE | ORAL | 11090280 | March 3, 2026 | TEMPORARY RELIEF OF MINOR ACHES AND PAINS |
EQ 20MG BASE;375MG | VIMOVO | HORIZON | N022511 | April 30, 2010 | RX | TABLET, DELAYED RELEASE | ORAL | 9393208 | Sept. 3, 2029 | RISK-REDUCTION OF NSAID-ASSOCIATED GASTRIC ULCER IN PATIENTS REQUIRING NSAID TREATMENT |
EQ 20MG BASE;500MG | VIMOVO | HORIZON | N022511 | April 30, 2010 | RX | TABLET, DELAYED RELEASE | ORAL | 9393208 | Sept. 3, 2029 | RISK-REDUCTION OF NSAID-ASSOCIATED GASTRIC ULCER IN PATIENTS REQUIRING NSAID TREATMENT |
EQ 20MG BASE;500MG | VIMOVO | HORIZON | N022511 | April 30, 2010 | RX | TABLET, DELAYED RELEASE | ORAL | 9220698 | March 10, 2031 | RISK-REDUCTION OF NSAID-ASSOCIATED GASTRIC ULCER IN PATIENTS REQUIRING NSAID TREATMENT |
EQ 20MG BASE;375MG | VIMOVO | HORIZON | N022511 | April 30, 2010 | RX | TABLET, DELAYED RELEASE | ORAL | 8945621 | Oct. 17, 2031 | RISK-REDUCTION OF NSAID-ASSOCIATED GASTRIC ULCERS IN PATIENTS ALSO TAKING LOW DOSE ASPIRIN |
EQ 20MG BASE;500MG | VIMOVO | HORIZON | N022511 | April 30, 2010 | RX | TABLET, DELAYED RELEASE | ORAL | 8945621 | Oct. 17, 2031 | RISK-REDUCTION OF NSAID-ASSOCIATED GASTRIC ULCERS IN PATIENTS ALSO TAKING LOW DOSE ASPIRIN |
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 | Enzyme | INHIBITOR | IC50 | 5.60 | CHEMBL | CHEMBL | |||
Prostaglandin G/H synthase 1 | Enzyme | INHIBITOR | IC50 | 5.16 | WOMBAT-PK | CHEMBL | |||
Aldo-keto reductase family 1 member C2 | Enzyme | IC50 | 4.50 | CHEMBL | |||||
Aldo-keto reductase family 1 member C3 | Enzyme | IC50 | 6.32 | CHEMBL | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 6.74 | CHEMBL | |||||
Prostaglandin-H2 D-isomerase | Enzyme | IC50 | 4.89 | CHEMBL | |||||
Prostaglandin G/H synthase 2 | Enzyme | IC50 | 5.47 | CHEMBL | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 4.96 | CHEMBL | |||||
Hormone-sensitive lipase | Enzyme | IC50 | 5.92 | CHEMBL | |||||
Cyclooxygenase | Enzyme | IC50 | 7.22 | CHEMBL |
ID | Source |
---|---|
4018847 | VUID |
N0000147149 | NUI |
D00118 | KEGG_DRUG |
26159-34-2 | SECONDARY_CAS_RN |
4018846 | VANDF |
4018847 | VANDF |
C0027396 | UMLSCUI |
CHEBI:59527 | CHEBI |
NPS | PDB_CHEM_ID |
CHEMBL154 | ChEMBL_ID |
DB00788 | DRUGBANK_ID |
CHEMBL1200806 | ChEMBL_ID |
D009288 | MESH_DESCRIPTOR_UI |
156391 | PUBCHEM_CID |
5230 | IUPHAR_LIGAND_ID |
2979 | INN_ID |
57Y76R9ATQ | UNII |
142442 | RXNORM |
2108 | MMSL |
2111 | MMSL |
27852 | MMSL |
5155 | MMSL |
5156 | MMSL |
6350 | MMSL |
8137 | MMSL |
d00019 | MMSL |
002380 | NDDF |
002381 | NDDF |
11847009 | SNOMEDCT_US |
372588000 | SNOMEDCT_US |
42692007 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Naproxen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0054-3630 | SUSPENSION | 125 mg | ORAL | ANDA | 28 sections |
Naproxen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0054-3630 | SUSPENSION | 125 mg | ORAL | ANDA | 28 sections |
Naproxen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1005 | TABLET, DELAYED RELEASE | 375 mg | ORAL | ANDA | 28 sections |
Naproxen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1006 | TABLET, DELAYED RELEASE | 500 mg | ORAL | ANDA | 28 sections |
Good Sense Naproxen Sodium | HUMAN OTC DRUG LABEL | 1 | 0113-0901 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
good sense naproxen sodium | HUMAN OTC DRUG LABEL | 1 | 0113-1412 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
good sense naproxen sodium | HUMAN OTC DRUG LABEL | 1 | 0113-1773 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
Good Sense Naproxen Sodium | HUMAN OTC DRUG LABEL | 1 | 0113-4368 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
basic care naproxen sodium | HUMAN OTC DRUG LABEL | 1 | 0113-7033 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
basic care naproxen sodium pm | HUMAN OTC DRUG LABEL | 2 | 0113-7264 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
Basic Care Naproxen Sodium | HUMAN OTC DRUG LABEL | 1 | 0113-7368 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
basic care naproxen sodium | HUMAN OTC DRUG LABEL | 1 | 0113-7901 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 16 sections |
good sense naproxen sodium | HUMAN OTC DRUG LABEL | 2 | 0113-8264 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
good sense naproxen sodium | HUMAN OTC DRUG LABEL | 2 | 0113-8264 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
good sense naproxen sodium | HUMAN OTC DRUG LABEL | 2 | 0113-8264 | TABLET, FILM COATED | 220 mg | ORAL | ANDA | 16 sections |
Naprosyn | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-0899 | SUSPENSION | 125 mg | ORAL | NDA | 29 sections |
Naprosyn | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-1798 | SUSPENSION | 250 mg | ORAL | NDA | 29 sections |
Naprosyn | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-2697 | SUSPENSION | 500 mg | ORAL | NDA | 29 sections |
Aleve Headache Pain | HUMAN OTC DRUG LABEL | 1 | 0280-0041 | TABLET | 220 mg | ORAL | NDA | 17 sections |
Aleve Headache Pain | HUMAN OTC DRUG LABEL | 1 | 0280-0041 | TABLET | 220 mg | ORAL | NDA | 17 sections |
Menstridol | HUMAN OTC DRUG LABEL | 1 | 0280-0270 | TABLET | 220 mg | ORAL | NDA | 17 sections |
Aleve PM | HUMAN OTC DRUG LABEL | 2 | 0280-1200 | TABLET, FILM COATED | 220 mg | ORAL | NDA | 17 sections |
Aleve PM | HUMAN OTC DRUG LABEL | 2 | 0280-1200 | TABLET, FILM COATED | 220 mg | ORAL | NDA | 17 sections |
Aleve PM | HUMAN OTC DRUG LABEL | 2 | 0280-1200 | TABLET, FILM COATED | 220 mg | ORAL | NDA | 17 sections |
AleveCaplets | HUMAN OTC DRUG LABEL | 1 | 0280-6000 | TABLET | 220 mg | ORAL | NDA | 17 sections |
AleveCaplets | HUMAN OTC DRUG LABEL | 1 | 0280-6000 | TABLET | 220 mg | ORAL | NDA | 17 sections |
AleveCaplets | HUMAN OTC DRUG LABEL | 1 | 0280-6000 | TABLET | 220 mg | ORAL | NDA | 17 sections |
Aleve | HUMAN OTC DRUG LABEL | 1 | 0280-6010 | TABLET | 220 mg | ORAL | NDA | 17 sections |
Aleve | HUMAN OTC DRUG LABEL | 1 | 0280-6010 | TABLET | 220 mg | ORAL | NDA | 17 sections |
Aleve | HUMAN OTC DRUG LABEL | 1 | 0280-6010 | TABLET | 220 mg | ORAL | NDA | 17 sections |