mephenesin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
1691 59-47-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • mephenesin
  • cresoxydiol
  • cresoxypropanediol
  • dioloxol
  • memphenesin
  • mephedan
  • mephenesine
  • mephesin
  • o-Cresyl glycerol ether
A centrally acting muscle relaxant with a short duration of action.
  • Molecular weight: 182.22
  • Formula: C10H14O3
  • CLOGP: 0.86
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 49.69
  • ALOGS: -0.94
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,JAK3,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIK3CG,PRKDC,TEK,TGFBR1 27
kinase-selectivity-class AXL,BRAF,CDK9,ERBB2,GRK2,PDK4,SIK2,SIK3 8
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M03BX06 MUSCULO-SKELETAL SYSTEM
MUSCLE RELAXANTS
MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
Other centrally acting agents
MeSH PA D009125 Muscle Relaxants, Central
MeSH PA D009465 Neuromuscular Agents

Related Drugs by ATC class:

M03BX Other centrally acting agents 9 drugs
baclofencyclobenzaprineeperisonefenyramidolpridinoltetrazepamthiocolchicosidetizanidinetolperisone

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000166815 NUI
D02595 KEGG_DRUG
C0025379 UMLSCUI
CHEBI:94398 CHEBI
CHEMBL229128 ChEMBL_ID
DB13583 DRUGBANK_ID
D008615 MESH_DESCRIPTOR_UI
4059 PUBCHEM_CID
171 INN_ID
7B8PIR2954 UNII
6755 RXNORM
001668 NDDF
72522000 SNOMEDCT_US

Pharmaceutical products:

None