tetrazepam 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
diazepam derivatives	2614	10379-14-3

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: tetrazepam myolastan	Molecular weight: 288.78 Formula: C16H17ClN2O CLOGP: 3.68 LIPINSKI: 0 HAC: 3 HDO: 0 TPSA: 32.67 ALOGS: -3.83 ROTB: 1

Molecule

Description

Molfile Inchi Smiles

Synonyms:

tetrazepam
myolastan

Molecular weight: 288.78
Formula: C16H17ClN2O
CLOGP: 3.68
LIPINSKI: 0
HAC: 3
HDO: 0
TPSA: 32.67
ALOGS: -3.83
ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Cross sensitivity reaction	99.76	33.40	19	1069	2143	63485791
Dermatitis contact	83.11	33.40	22	1066	10986	63476948
Occupational exposure to product	63.81	33.40	13	1075	2065	63485869
Skin test positive	56.87	33.40	10	1078	722	63487212
Eczema	56.11	33.40	21	1067	32270	63455664
Eczema eyelids	47.94	33.40	7	1081	153	63487781
Wrong technique in product usage process	45.82	33.40	22	1066	62318	63425616

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FDA Adverse Event Reporting System (Male)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Logorrhoea	94.56	74.34	18	491	2408	34954014
Transposition of the great vessels	92.96	74.34	14	495	455	34955967
Vestibular disorder	80.95	74.34	14	495	1093	34955329

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FDA Adverse Event Reporting System (Geriatric)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Toxicity to various agents	99.99	33.04	63	939	421477	79321909
Cross sensitivity reaction	95.41	33.04	19	983	3693	79739693
Dermatitis contact	89.85	33.04	22	980	11011	79732375
Logorrhoea	86.50	33.04	18	984	4347	79739039
Occupational exposure to product	81.97	33.04	13	989	687	79742699
Vestibular disorder	71.78	33.04	14	988	2441	79740945
Skin test positive	55.26	33.04	10	992	1164	79742222
Psychomotor skills impaired	50.61	33.04	12	990	5225	79738161
Eczema eyelids	48.87	33.04	7	995	184	79743202
Wrong technique in product usage process	48.79	33.04	22	980	73853	79669533

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FDA Adverse Event Reporting System (Pediatric)

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Pharmacologic Action:

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Source	Code	Description
ATC	M03BX07	MUSCULO-SKELETAL SYSTEM MUSCLE RELAXANTS MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS Other centrally acting agents
MeSH PA	D002491	Central Nervous System Agents
MeSH PA	D009125	Muscle Relaxants, Central
MeSH PA	D009465	Neuromuscular Agents
MeSH PA	D018373	Peripheral Nervous System Agents

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Drug Use | Suggest Off label Use Form| |View source of the data|

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🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	5.8	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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ID	Source
005346	NDDF
2182	INN_ID
25215	PUBCHEM_CID
37985	RXNORM
698845008	SNOMEDCT_US
C005245	MESH_SUPPLEMENTAL_RECORD_UI
C0076341	UMLSCUI
CHEBI:135198	CHEBI
CHEMBL2105527	ChEMBL_ID
D07277	KEGG_DRUG

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Pharmaceutical products:

None