mebutizide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diuretics, chlorothiazide derivatives 1645 3568-00-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • mebutizide
  • mebuthiazide
  • mebutizid
  • Molecular weight: 381.89
  • Formula: C13H20ClN3O4S2
  • CLOGP: 2.54
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 118.36
  • ALOGS: -3.07
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C03AA13 CARDIOVASCULAR SYSTEM
DIURETICS
LOW-CEILING DIURETICS, THIAZIDES
Thiazides, plain
ATC C03EA05 CARDIOVASCULAR SYSTEM
DIURETICS
DIURETICS AND POTASSIUM-SPARING AGENTS IN COMBINATION
Low-ceiling diuretics and potassium-sparing agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.74 acidic
pKa2 10.46 acidic
pKa3 1.35 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07172 KEGG_DRUG
C0603520 UMLSCUI
CHEBI:135597 CHEBI
CHEMBL2105212 ChEMBL_ID
DB13430 DRUGBANK_ID
C008338 MESH_SUPPLEMENTAL_RECORD_UI
71652 PUBCHEM_CID
1859 INN_ID
7738AS8324 UNII

Pharmaceutical products:

None