altizide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diuretics, chlorothiazide derivatives 140 5588-16-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • altizide
  • aldactazine
  • althiazide
  • althizide
  • altizid
  • racemic althiazide
  • altizida
  • Molecular weight: 383.88
  • Formula: C11H14ClN3O4S3
  • CLOGP: 1.05
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 118.36
  • ALOGS: -2.96
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C03EA04 CARDIOVASCULAR SYSTEM
DIURETICS
DIURETICS AND POTASSIUM-SPARING AGENTS IN COMBINATION
Low-ceiling diuretics and potassium-sparing agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypertensive disorder indication 38341003 DOID:10763
Edema indication 267038008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.89 acidic
pKa2 10.88 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02838 KEGG_DRUG
17599 RXNORM
C0051500 UMLSCUI
CHEBI:91768 CHEBI
CHEMBL599870 ChEMBL_ID
C006480 MESH_SUPPLEMENTAL_RECORD_UI
2122 PUBCHEM_CID
717101002 SNOMEDCT_US
1382 INN_ID
GI8CB72B0D UNII
005226 NDDF

Pharmaceutical products:

None