DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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Smart API
Redial
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
bekanamycin 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
antibiotics, produced by Streptomyces strains
1520
4696-76-8
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
bekanamycin
Kanamycin B
aminodeoxykanamycin
kanendomycin
Nebramycin V
kanendomycin is the sulfate of bekanamycin; RN given refers to parent cpd; structure
Molecular weight: 483.52
Formula: C18H37N5O10
CLOGP: -3.85
LIPINSKI: 2
HAC: 15
HDO: 11
TPSA: 288.40
ALOGS: -0.80
ROTB: 6
Drug dosage:
Dose
Unit
Route
0.60
g
P
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
J01GB13
ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
AMINOGLYCOSIDE ANTIBACTERIALS
Other aminoglycosides
MeSH PA
D000900
Anti-Bacterial Agents
MeSH PA
D000890
Anti-Infective Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
13.0
acidic
pKa2
13.56
acidic
pKa3
13.99
acidic
pKa4
8.03
Basic
pKa5
7.6
Basic
pKa6
7.07
Basic
pKa7
6.11
Basic
pKa8
5.41
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
3-oxoacyl-[acyl-carrier-protein] synthase 3
Enzyme
C3TDZ2_ECOLX
IC50
5.20
CHEMBL
3-oxoacyl-[acyl-carrier-protein] synthase 3
Unclassified
FABH_ECOLI
IC50
5.25
CHEMBL
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External reference:
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ID
Source
9CS
PDB_CHEM_ID
12182
IUPHAR_LIGAND_ID
15JT14C3GI
UNII
2838
INN_ID
439318
PUBCHEM_CID
C001495
MESH_SUPPLEMENTAL_RECORD_UI
C0053076
UMLSCUI
CHEBI:28098
CHEBI
CHEMBL176
ChEMBL_ID
D07497
KEGG_DRUG
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Pharmaceutical products:
None
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bekanamycin