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chlorphenesin carbamate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| tranquillizers, propanediol and pentanediol derivatives | 614 | 886-74-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A centrally acting muscle relaxant. Its mode of action is unknown. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1203)
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,EIF2AK3,ERBB2,GRK2,ITK,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PRKDC,TEK | 19 | |||
| kinase-selectivity-class | AXL,BRAF,CDK9,EIF2AK3,ERBB2,GRK2,MAPK7,PDK4,SIK2,STK33 | 10 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| June 14, 1965 | FDA | PHARMACIA AND UPJOHN |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D01AE07 | DERMATOLOGICALS ANTIFUNGALS FOR DERMATOLOGICAL USE ANTIFUNGALS FOR TOPICAL USE Other antifungals for topical use |
| CHEBI has role | CHEBI:36047 | antibacterial drug |
| CHEBI has role | CHEBI:51371 | muscle relaxant |
| CHEBI has role | CHEBI:86327 | antifungal drug |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
| MeSH PA | D009125 | Muscle Relaxants, Central |
| MeSH PA | D009465 | Neuromuscular Agents |
Related Drugs by ATC class:
D01AE Other antifungals for topical use 23 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Spasticity | indication | 221360009 |
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Dogs | Discomfort associated with myositis, muscle sprains, traumatic injuries, stifle injuries, and invertebral disc syndrome | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Maolate Tablets, Maolate Veterinary | Zoetis Inc. | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4018091 | VUID |
| N0000146429 | NUI |
| D00770 | KEGG_DRUG |
| 20880 | RXNORM |
| C0055467 | UMLSCUI |
| CHEBI:3643 | CHEBI |
| CHEMBL607710 | ChEMBL_ID |
| DB14656 | DRUGBANK_ID |
| C015071 | MESH_SUPPLEMENTAL_RECORD_UI |
| 2724 | PUBCHEM_CID |
| 57U5YI11WP | UNII |
| DB00856 | DRUGBANK_ID |
| 1563 | MMSL |
| 4424 | MMSL |
| d00961 | MMSL |
| 001674 | NDDF |
| 003806 | NDDF |
| 004678 | NDDF |
| 373778007 | SNOMEDCT_US |
| 73213007 | SNOMEDCT_US |
| 80311000 | SNOMEDCT_US |
| C0008280 | UMLSCUI |
| 104-29-0 | SECONDARY_CAS_RN |
| 7697 | PUBCHEM_CID |
| 825 | INN_ID |
| 4018091 | VANDF |
| 4019676 | VANDF |
| D002743 | MESH_DESCRIPTOR_UI |
| I670DAL4SZ | UNII |
| CHEBI:3642 | CHEBI |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Hand Sanitizer Smells Clean | HUMAN OTC DRUG LABEL | 3 | 75525-001 | GEL | 0.14 g | TOPICAL | OTC monograph not final | 12 sections |
| Wet Wipes | HUMAN OTC DRUG LABEL | 5 | 76693-101 | CLOTH | 0.10 g | TOPICAL | unapproved drug other | 12 sections |
| 99.99% Disinfection wipes | HUMAN OTC DRUG LABEL | 3 | 80515-002 | CLOTH | 0.37 g | TOPICAL | OTC monograph not final | 10 sections |
| AnubisMed | HUMAN OTC DRUG LABEL | 28 | 83021-551 | CREAM | 0.10 g | TOPICAL | OTC monograph final | 7 sections |
| Anubis Barcelona Protective Line | HUMAN OTC DRUG LABEL | 27 | 83021-686 | CREAM | 0.10 g | TOPICAL | OTC monograph final | 9 sections |