chlorphenesin carbamate Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
tranquillizers, propanediol and pentanediol derivatives 614 886-74-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • chlorphenesin carbamate
  • maolate
  • chlorphensin carbamate
A centrally acting muscle relaxant. Its mode of action is unknown. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1203)
  • Molecular weight: 245.66
  • Formula: C10H12ClNO4
  • CLOGP: 1.26
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 81.78
  • ALOGS: -2.25
  • ROTB: 6

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
June 14, 1965 FDA PHARMACIA AND UPJOHN

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:36047 antibacterial drugs
CHEBI has role CHEBI:51371 muscle relaxants
CHEBI has role CHEBI:86327 anti-fungal medications
MeSH PA D002491 Central Nervous System Agents
MeSH PA D009125 Muscle Relaxants, Central
MeSH PA D009465 Neuromuscular Agents
MeSH PA D018373 Peripheral Nervous System Agents

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Spasticity indication 221360009

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018091 VUID
N0000146429 NUI
D00770 KEGG_DRUG
104-29-0 SECONDARY_CAS_RN
C0055467 UMLSCUI
CHEBI:3643 CHEBI
CHEBI:3642 CHEBI
CHEMBL607710 ChEMBL_ID
DB14656 DRUGBANK_ID
C015071 MESH_SUPPLEMENTAL_RECORD_UI
2724 PUBCHEM_CID
825 INN_ID
57U5YI11WP UNII
7697 PUBCHEM_CID
DB00856 DRUGBANK_ID
I670DAL4SZ UNII
20880 RXNORM
1563 MMSL
4424 MMSL
d00961 MMSL
001674 NDDF
003806 NDDF
004678 NDDF
373778007 SNOMEDCT_US
73213007 SNOMEDCT_US
80311000 SNOMEDCT_US
D002743 MESH_DESCRIPTOR_UI
4018091 VANDF
4019676 VANDF
C0008280 UMLSCUI

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Hand Sanitizer Smells Clean HUMAN OTC DRUG LABEL 3 75525-001 GEL 0.14 g TOPICAL OTC monograph not final 12 sections
Wet Wipes HUMAN OTC DRUG LABEL 5 76693-101 CLOTH 0.10 g TOPICAL unapproved drug other 12 sections
99.99% Disinfection wipes HUMAN OTC DRUG LABEL 3 80515-002 CLOTH 0.37 g TOPICAL OTC monograph not final 10 sections