haloprogin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 1355 | 777-11-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
minor descriptor (73-86); on-line & INDEX MEDICUS search PHENYL ETHERS (73-86)
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA | WESTWOOD SQUIBB |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D01AE11 | DERMATOLOGICALS ANTIFUNGALS FOR DERMATOLOGICAL USE ANTIFUNGALS FOR TOPICAL USE Other antifungals for topical use |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000935 | Antifungal Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Tinea pedis | indication | 6020002 | DOID:12403 |
| Tinea corporis | indication | 84849002 | |
| Tinea cruris | indication | 399029005 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| D(1A) dopamine receptor | GPCR | Ki | 6.55 | DRUG MATRIX | |||||
| Alpha-2A adrenergic receptor | GPCR | Ki | 6.34 | DRUG MATRIX | |||||
| Sodium-dependent serotonin transporter | Transporter | Ki | 6.37 | DRUG MATRIX | |||||
| Sodium-dependent noradrenaline transporter | Transporter | Ki | 5.56 | DRUG MATRIX | |||||
| 5-hydroxytryptamine receptor 2A | GPCR | Ki | 6.16 | DRUG MATRIX | |||||
| 5-hydroxytryptamine receptor 2C | GPCR | Ki | 5.87 | DRUG MATRIX | |||||
| 5-hydroxytryptamine receptor 6 | GPCR | Ki | 5.73 | DRUG MATRIX | |||||
| Alpha-2B adrenergic receptor | GPCR | Ki | 6.60 | DRUG MATRIX | |||||
| D(3) dopamine receptor | GPCR | Ki | 6.78 | DRUG MATRIX | |||||
| Alpha-2C adrenergic receptor | GPCR | Ki | 6.23 | DRUG MATRIX | |||||
| Sodium-dependent dopamine transporter | Transporter | Ki | 5.81 | DRUG MATRIX | |||||
| Adenosine receptor A3 | GPCR | Ki | 6.90 | DRUG MATRIX | |||||
| Kappa-type opioid receptor | GPCR | Ki | 6.34 | DRUG MATRIX | |||||
| Substance-K receptor | GPCR | Ki | 6.31 | DRUG MATRIX | |||||
| UDP-glucose 4-epimerase | Enzyme | IC50 | 6.30 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 4018665 | VUID |
| N0000146976 | NUI |
| D00339 | KEGG_DRUG |
| 4018665 | VANDF |
| C0062106 | UMLSCUI |
| CHEBI:5614 | CHEBI |
| CHEMBL1289 | ChEMBL_ID |
| DB00793 | DRUGBANK_ID |
| C100276 | MESH_SUPPLEMENTAL_RECORD_UI |
| 3561 | PUBCHEM_CID |
| 2263 | INN_ID |
| AIU7053OWL | UNII |
| 26422 | RXNORM |
| 4819 | MMSL |
| 002913 | NDDF |
| 387251004 | SNOMEDCT_US |
| 46436003 | SNOMEDCT_US |
Pharmaceutical products:
None