amorolfine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 188 | 78613-35-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Pseudoaldosteronism | 49.35 | 44.39 | 5 | 78 | 70 | 63488869 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Pseudoaldosteronism | 75.28 | 61.43 | 9 | 345 | 167 | 79743867 |
| Pathogen resistance | 61.85 | 61.43 | 14 | 340 | 14328 | 79729706 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D01AE16 | DERMATOLOGICALS ANTIFUNGALS FOR DERMATOLOGICAL USE ANTIFUNGALS FOR TOPICAL USE Other antifungals for topical use |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000935 | Antifungal Agents |
| CHEBI has role | CHEBI:59285 | squalene monooxygenase inhibitors |
| CHEBI has role | CHEBI:83319 | 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitor |
| CHEBI has role | CHEBI:86385 | Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.3 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01720 | KEGG_DRUG |
| 17804 | RXNORM |
| C0051736 | UMLSCUI |
| CHEBI:599440 | CHEBI |
| CHEMBL489411 | ChEMBL_ID |
| DB09056 | DRUGBANK_ID |
| C038974 | MESH_SUPPLEMENTAL_RECORD_UI |
| 54260 | PUBCHEM_CID |
| 5855 | INN_ID |
| 78613-38-4 | SECONDARY_CAS_RN |
| AB0BHP2FH0 | UNII |
| 332998007 | SNOMEDCT_US |
| 391769002 | SNOMEDCT_US |
| 391770001 | SNOMEDCT_US |
| 003929 | NDDF |
| 004122 | NDDF |
Pharmaceutical products:
None