amorolfine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
188 78613-35-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • amorolfine
  • loceryl
  • amorolfine hydrochloride
  • amorolfine HCl
  • Molecular weight: 317.52
  • Formula: C21H35NO
  • CLOGP: 6.24
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 0
  • TPSA: 12.47
  • ALOGS: -5.61
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pathogen resistance 62.97 55.89 14 289 12529 64485900
Pseudoaldosteronism 58.19 55.89 7 296 129 64498300

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D01AE16 DERMATOLOGICALS
ANTIFUNGALS FOR DERMATOLOGICAL USE
ANTIFUNGALS FOR TOPICAL USE
Other antifungals for topical use
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000935 Antifungal Agents
CHEBI has role CHEBI:59285 squalene monooxygenase inhibitors
CHEBI has role CHEBI:83319 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitor
CHEBI has role CHEBI:86385 Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.3 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01720 KEGG_DRUG
17804 RXNORM
C0051736 UMLSCUI
CHEBI:599440 CHEBI
CHEMBL489411 ChEMBL_ID
DB09056 DRUGBANK_ID
C038974 MESH_SUPPLEMENTAL_RECORD_UI
54260 PUBCHEM_CID
5855 INN_ID
78613-38-4 SECONDARY_CAS_RN
AB0BHP2FH0 UNII
003929 NDDF
004122 NDDF
332998007 SNOMEDCT_US
391769002 SNOMEDCT_US
391770001 SNOMEDCT_US

Pharmaceutical products:

None