ethyl hydroxybenzoate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4773 120-47-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ethyl hydroxybenzoate
  • ethylparaben
  • ethyl parasept
  • mycocten
  • Molecular weight: 166.18
  • Formula: C9H10O3
  • CLOGP: 2.51
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 46.53
  • ALOGS: -1.82
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D01AE10 DERMATOLOGICALS
ANTIFUNGALS FOR DERMATOLOGICAL USE
ANTIFUNGALS FOR TOPICAL USE
Other antifungals for topical use
FDA CS M0000728 Allergens
FDA PE N0000175629 Increased Histamine Release
FDA PE N0000184306 Cell-mediated Immunity
FDA EPC N0000185508 Standardized Chemical Allergen
CHEBI has role CHEBI:35718 antifungal agents
CHEBI has role CHEBI:65256 antimicrobial food preservatives
CHEBI has role CHEBI:76924 plant metabolites
CHEBI has role CHEBI:76989 phytoestrogens

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.39 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Carbonic anhydrase 2 Enzyme Ki 5.32 CHEMBL
Estrogen receptor Nuclear hormone receptor EC50 4.42 CHEMBL
Carbonic anhydrase 1 Enzyme Ki 5.10 CHEMBL
Estrogen receptor beta Nuclear hormone receptor EC50 5.73 CHEMBL
Carbonic anhydrase 9 Enzyme Ki 5.09 CHEMBL
Carbonic anhydrase 12 Enzyme Ki 5.07 CHEMBL
Carbonic anhydrase 7 Enzyme Ki 5.06 CHEMBL
Carbonic anhydrase 14 Enzyme Ki 5.11 CHEMBL

External reference:

IDSource
CHEBI:88839 CHEBI
E4B PDB_CHEM_ID
CHEMBL15841 ChEMBL_ID
DB13628 DRUGBANK_ID
1362892 RXNORM
NOCODE MMSL
005164 NDDF
255864002 SNOMEDCT_US
411198001 SNOMEDCT_US
C3652694 UMLSCUI
8434 PUBCHEM_CID
14255EXE39 UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Anubis Barcelona HUMAN OTC DRUG LABEL 27 83021-617 CONCENTRATE 0 g TOPICAL OTC monograph final 9 sections
Anubis Barcelona HUMAN OTC DRUG LABEL 27 83021-617 CONCENTRATE 0 g TOPICAL OTC monograph final 9 sections
Anubis Barcelona Regul OIl HUMAN OTC DRUG LABEL 27 83021-624 CONCENTRATE 0 g TOPICAL OTC monograph final 9 sections
Anubis Barcelona Regul OIl HUMAN OTC DRUG LABEL 27 83021-624 CONCENTRATE 0 g TOPICAL OTC monograph final 9 sections