carfecillin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, 6-aminopenicillanic acid derivatives 507 27025-49-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • carfecillin sodium
  • BRL-3475
  • carfecillin
  • carbenicillin phenyl
  • carbenicillin phenyl ester
The phenyl ester of CARBENICILLIN that, upon oral administration, is broken down in the intestinal mucosa to the active antibacterial. It is used for urinary tract infections.
  • Molecular weight: 454.50
  • Formula: C23H22N2O6S
  • CLOGP: 3.17
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 2
  • TPSA: 113.01
  • ALOGS: -4.40
  • ROTB: 7

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC G01AA08 GENITO URINARY SYSTEM AND SEX HORMONES
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Antibiotics
FDA CS M0016152 Penicillins
FDA EPC N0000175497 Penicillin-class Antibacterial
CHEBI has role CHEBI:36047 antibacterial drugs
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000892 Anti-Infective Agents, Urinary

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.79 acidic
pKa2 10.83 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02199 KEGG_DRUG
2015 RXNORM
C0007241 UMLSCUI
CHEBI:3414 CHEBI
CHEBI:3393 CHEBI
0JM PDB_CHEM_ID
CHEMBL1095283 ChEMBL_ID
CHEMBL2105996 ChEMBL_ID
D002323 MESH_DESCRIPTOR_UI
DB13506 DRUGBANK_ID
12288 IUPHAR_LIGAND_ID
33672 PUBCHEM_CID
d00092 MMSL
323761001 SNOMEDCT_US
34731007 SNOMEDCT_US
350166000 SNOMEDCT_US
372713001 SNOMEDCT_US
417288007 SNOMEDCT_US
C0006976 UMLSCUI
DB00578 DRUGBANK_ID
4019654 VANDF
3487 INN_ID
2516 INN_ID
D002228 MESH_DESCRIPTOR_UI
20824 PUBCHEM_CID
9UU4XDB74X UNII
002700 NDDF
003946 NDDF

Pharmaceutical products:

None