pentamycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, polyene derivatives 3254 6834-98-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • fungchromin
  • fungichromin
  • cantricin
  • cogomycin
  • lagosin
  • pentamycin
  • Molecular weight: 670.84
  • Formula: C35H58O12
  • CLOGP: 2.47
  • LIPINSKI: 3
  • HAC: 12
  • HDO: 10
  • TPSA: 228.60
  • ALOGS: -3.51
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,ERBB2,GRK2,ITK,JAK3,MAP2K6,MAP3K21,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PRKDC,TEK,TGFBR1,ZAP70 26
kinase-selectivity-class AXL,CDK4,GRK2,MAP2K6 4
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC G01AA11 GENITO URINARY SYSTEM AND SEX HORMONES
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Antibiotics

Related Drugs by ATC class:

G01AA Antibiotics 10 drugs
amphotericin Bcandicidincarfecillinchloramphenicolclindamycinhachimycinmepartricinnatamycinnystatinoxytetracycline

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.74 acidic
pKa2 13.55 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01829 KEGG_DRUG
C0060838 UMLSCUI
CHEBI:31639 CHEBI
CHEMBL2272031 ChEMBL_ID
DB13571 DRUGBANK_ID
C011827 MESH_SUPPLEMENTAL_RECORD_UI
1JB340D58S UNII
5282200 PUBCHEM_CID

Pharmaceutical products:

None