succinimide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4723 123-56-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • succinimide
  • butanimide
  • succinic acid imide
  • succinic imide
  • Molecular weight: 99.09
  • Formula: C4H5NO2
  • CLOGP: -1.17
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 46.17
  • ALOGS: 0.36
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC G04BX10 GENITO URINARY SYSTEM AND SEX HORMONES
UROLOGICALS
UROLOGICALS
Other urologicals

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Primary hyperoxaluria indication 17901006 DOID:2977




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.18 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Protein cereblon Cytosolic other Ki 4.58 CHEMBL
Cereblon isoform 4 Unclassified Ki 5.37 CHEMBL

External reference:

IDSource
CHEBI:9307 CHEBI
SZB PDB_CHEM_ID
CHEMBL275661 ChEMBL_ID
C032620 MESH_SUPPLEMENTAL_RECORD_UI
DB13376 DRUGBANK_ID
10X90O3503 UNII
005461 NDDF
372837008 SNOMEDCT_US
74632002 SNOMEDCT_US
C0038623 UMLSCUI
11439 PUBCHEM_CID

Pharmaceutical products:

None