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phenyl salicylate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 3462 | 118-55-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 2 | g | O |
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK2,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK | 40 | |||
| kinase-selectivity-class | ACVR2A,ACVR2B,AXL,ERBB2,GRK2,MAP2K6,PDK4,STK33,TEK,TTK | 10 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | G04BX12 | GENITO URINARY SYSTEM AND SEX HORMONES UROLOGICALS UROLOGICALS Other urologicals |
| CHEBI has role | CHEBI:73335 | ultraviolet filter |
Related Drugs by ATC class:
G04BX Other urologicals 10 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Gastritis | contraindication | 4556007 | DOID:4029 |
| Hypocalcemia | contraindication | 5291005 | |
| Severe chronic ulcerative colitis | contraindication | 14311001 | |
| Disorder of autonomic nervous system | contraindication | 15241006 | |
| Cirrhosis of liver | contraindication | 19943007 | DOID:5082 |
| Hyperphosphatemia | contraindication | 20165001 | DOID:0050459 |
| Glaucoma | contraindication | 23986001 | DOID:1686 |
| Toxic megacolon | contraindication | 28536002 | DOID:1770 |
| Atony of colon | contraindication | 29479008 | |
| Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
| Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
| Hypernatremia | contraindication | 39355002 | |
| Hypovolemic shock | contraindication | 39419009 | |
| Gastrointestinal ulcer | contraindication | 40845000 | |
| Body fluid retention | contraindication | 43498006 | |
| Conduction disorder of the heart | contraindication | 44808001 | |
| Achalasia of esophagus | contraindication | 45564002 | DOID:9164 |
| Chronic heart failure | contraindication | 48447003 | |
| Disorder of cardiovascular system | contraindication | 49601007 | DOID:1287 |
| Vitamin K deficiency | contraindication | 52675005 | DOID:11249 |
| Nasal polyp | contraindication | 52756005 | |
| Paralytic ileus | contraindication | 55525008 | DOID:8442 |
| Acute nephropathy | contraindication | 58574008 | |
| Hepatic failure | contraindication | 59927004 | |
| Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
| Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
| Factor II deficiency | contraindication | 73975000 | |
| Gastrointestinal hemorrhage | contraindication | 74474003 | |
| Thrombotic thrombocytopenic purpura | contraindication | 78129009 | DOID:10772 |
| Hiatal hernia | contraindication | 84089009 | DOID:12642 |
| Kidney disease | contraindication | 90708001 | DOID:557 |
| Thyrotoxicosis | contraindication | 90739004 | DOID:7997 |
| Hemophilia | contraindication | 90935002 | |
| Myasthenia gravis | contraindication | 91637004 | DOID:437 |
| Anemia due to enzyme deficiency | contraindication | 111577008 | |
| Deficiency of glucose-6-phosphate dehydrogenase | contraindication | 124134002 | DOID:2862 |
| Liver function tests abnormal | contraindication | 166603001 | |
| Gastroesophageal reflux disease | contraindication | 235595009 | DOID:8534 |
| Disease of liver | contraindication | 235856003 | DOID:409 |
| Bladder outflow obstruction | contraindication | 236645006 | |
| Pyloric obstruction | contraindication | 244815007 | |
| Benign prostatic hyperplasia | contraindication | 266569009 | |
| Edema | contraindication | 267038008 | |
| Anemia | contraindication | 271737000 | DOID:2355 |
| Pregnancy, function | contraindication | 289908002 | |
| Cardiovascular event risk | contraindication | 395112001 | |
| Breastfeeding (mother) | contraindication | 413712001 | |
| Disorder of coronary artery | contraindication | 414024009 | |
| Fever greater than 100.4 Fahrenheit | contraindication | 426000000 | |
| Severe dehydration | contraindication | 450316000 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.43 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4019042 | VUID |
| N0000179236 | NUI |
| 4018580 | VANDF |
| 4019042 | VANDF |
| C0073999 | UMLSCUI |
| CHEMBL1339216 | ChEMBL_ID |
| DB11071 | DRUGBANK_ID |
| 8361 | PUBCHEM_CID |
| C026041 | MESH_SUPPLEMENTAL_RECORD_UI |
| 28A37T47QO | UNII |
| 36122 | RXNORM |
| 5281 | MMSL |
| d03087 | MMSL |
| 001597 | NDDF |
| 255898006 | SNOMEDCT_US |
| 411256006 | SNOMEDCT_US |
| CHEBI:34918 | CHEBI |
| 28A37T47QO | INXIGHT DRUGS |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| URELLE | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0037-6321 | TABLET | 32.40 mg | ORAL | Unapproved drug other | 12 sections |
| URIBEL | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0076-0111 | CAPSULE | 36 mg | ORAL | unapproved drug other | 20 sections |
| Hyophen | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0076-0901 | TABLET | 36.20 mg | ORAL | unapproved drug other | 19 sections |
| Phosphasal | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0076-0902 | TABLET | 36.20 mg | ORAL | unapproved drug other | 20 sections |
| Ustell | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0076-0903 | CAPSULE | 36 mg | ORAL | unapproved drug other | 20 sections |
| URIBEL TABS | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0178-0745 | TABLET, COATED | 36.20 mg | ORAL | unapproved drug other | 13 sections |
| Uretron D/S | HUMAN PRESCRIPTION DRUG LABEL | 5 | 12539-144 | TABLET | 36.20 mg | ORAL | unapproved drug other | 20 sections |
| UroAv-81 | HUMAN PRESCRIPTION DRUG LABEL | 5 | 15338-502 | TABLET | 32.40 mg | ORAL | unapproved drug other | 18 sections |
| UroAv-B | HUMAN PRESCRIPTION DRUG LABEL | 5 | 15338-503 | CAPSULE | 36 mg | ORAL | unapproved drug other | 18 sections |
| URIMAR-T CAPS | HUMAN PRESCRIPTION DRUG LABEL | 5 | 28595-224 | CAPSULE | 36.20 mg | ORAL | unapproved drug other | 19 sections |
| MB CAPS | HUMAN PRESCRIPTION DRUG LABEL | 5 | 28595-299 | CAPSULE | 36.20 mg | ORAL | unapproved drug other | 18 sections |
| UrinD/S | HUMAN PRESCRIPTION DRUG LABEL | 5 | 54859-701 | TABLET | 36.20 mg | ORAL | Unapproved drug other | 17 sections |
| Uro-MP | HUMAN PRESCRIPTION DRUG LABEL | 5 | 58657-456 | CAPSULE | 36 mg | ORAL | unapproved drug other | 18 sections |
| Uro-MP | HUMAN PRESCRIPTION DRUG LABEL | 5 | 58657-456 | CAPSULE | 36 mg | ORAL | unapproved drug other | 18 sections |
| Vilevev MB | HUMAN PRESCRIPTION DRUG LABEL | 5 | 71186-000 | TABLET | 32.40 mg | ORAL | UNAPPROVED DRUG OTHER | 18 sections |
| Vilamit MB | HUMAN PRESCRIPTION DRUG LABEL | 5 | 71186-002 | CAPSULE | 36 mg | ORAL | UNAPPROVED DRUG OTHER | 18 sections |
| UrNeva | HUMAN PRESCRIPTION DRUG LABEL | 5 | 79043-338 | CAPSULE | 36.20 mg | ORAL | unapproved drug other | 19 sections |