bisoxatin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4356 17692-24-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bisoxatin
  • Molecular weight: 333.34
  • Formula: C20H15NO4
  • CLOGP: 2.77
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 78.79
  • ALOGS: -4.22
  • ROTB: 2

Drug dosage:

DoseUnitRoute
0.12 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,CDK5,EIF2AK3,GRK2,ITK,MAPK10,MAPK7,PDK1,PDK2,PDK4,PIK3CB,PIK3CG,PRKDC,TGFBR1 15
kinase-selectivity-class ACVR2B,GRK2,MAP2K6,RIPK1 4
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A06AB09 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR CONSTIPATION
DRUGS FOR CONSTIPATION
Contact laxatives

Related Drugs by ATC class:

A06AB Contact laxatives 6 drugs
bisacodylcastor oildantronoxyphenisatinephenolphthaleinsodium picosulfate

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.54 acidic
pKa2 9.14 acidic
pKa3 11.99 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07531 KEGG_DRUG
C3652923 UMLSCUI
CHEBI:31294 CHEBI
CHEMBL2106004 ChEMBL_ID
DB09219 DRUGBANK_ID
2348 INN_ID
7C75N0L7FP UNII
28689 PUBCHEM_CID

Pharmaceutical products:

None