bisacodyl 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	375	603-50-9

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: bisacodyl brocalax dulcolax	A diphenylmethane stimulant laxative used for the treatment of CONSTIPATION and for bowel evacuation. (From Martindale, The Extra Pharmacopoeia, 30th ed, p871) Molecular weight: 361.40 Formula: C22H19NO4 CLOGP: 2.85 LIPINSKI: 0 HAC: 5 HDO: 0 TPSA: 65.49 ALOGS: -5.46 ROTB: 7 Status: OFM Legend: OFP - off patent OFM - off market ONP - on patent

Molecule

Description

Molfile Inchi Smiles

Synonyms:

bisacodyl
brocalax
dulcolax

A diphenylmethane stimulant laxative used for the treatment of CONSTIPATION and for bowel evacuation. (From Martindale, The Extra Pharmacopoeia, 30th ed, p871)

Molecular weight: 361.40
Formula: C22H19NO4
CLOGP: 2.85
LIPINSKI: 0
HAC: 5
HDO: 0
TPSA: 65.49
ALOGS: -5.46
ROTB: 7

Status: OFM

Legend:
OFP - off patent
OFM - off market
ONP - on patent

Drug dosage:

Dose	Unit	Route
10	mg	O
10	mg	R

ADMET properties:

Property	Value	Reference
BA (Bioavailability)	15 %	Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

Date	Agency	Company	Orphan
May 10, 2004	FDA	BRAINTREE

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Macular degeneration	384.69	12.48	156	17624	14232	50573112
Sedation complication	276.01	12.48	107	17673	8659	50578685
Cognitive disorder	265.38	12.48	175	17605	43948	50543396
Orthostatic hypotension	264.52	12.48	151	17629	29330	50558014
Creatinine renal clearance decreased	247.82	12.48	108	17672	11773	50575571
Sedation	235.67	12.48	142	17638	30468	50556876
Hypomania	208.41	12.48	73	17707	4432	50582912
Jaundice cholestatic	206.85	12.48	75	17705	5036	50582308
Blood calcium decreased	199.06	12.48	111	17669	20595	50566749
Schizophrenia	176.57	12.48	74	17706	7323	50580021
Balance disorder	173.04	12.48	165	17615	70425	50516919
Psychotic disorder	142.03	12.48	91	17689	21721	50565623
Depressed level of consciousness	132.14	12.48	124	17656	51829	50535515
Mobility decreased	102.21	12.48	133	17647	79815	50507529
Hypotension	96.90	12.48	238	17542	235231	50352113
Blood bilirubin increased	96.24	12.48	84	17696	31954	50555390
Hepatotoxicity	95.38	12.48	78	17702	27148	50560196
Fall	92.83	12.48	293	17487	334639	50252705
Cholelithiasis	76.76	12.48	80	17700	37893	50549451
Constipation	75.56	12.48	187	17593	185521	50401823
Intestinal pseudo-obstruction	71.11	12.48	21	17759	733	50586611
Toxicity to various agents	49.88	12.48	176	17604	212323	50375021
Rheumatoid arthritis	48.05	12.48	7	17773	202543	50384801
Alopecia	38.51	12.48	19	17761	245028	50342316
Vomiting	37.37	12.48	283	17497	460475	50126869
Drug intolerance	35.95	12.48	16	17764	219088	50368256
Systemic lupus erythematosus	35.41	12.48	4	17776	140618	50446726
Maternal exposure during pregnancy	34.63	12.48	7	17773	159771	50427573
Treatment failure	34.45	12.48	4	17776	137633	50449711
Joint swelling	34.26	12.48	22	17758	245264	50342080
Contraindicated product administered	33.40	12.48	6	17774	148952	50438392
Pneumonia	31.53	12.48	234	17546	378167	50209177
Arthropathy	30.17	12.48	9	17771	157897	50429447
Arthralgia	29.08	12.48	70	17710	438632	50148712
Death	28.69	12.48	204	17576	325175	50262169
Urinary retention	28.01	12.48	40	17740	26150	50561194
Drug hypersensitivity	27.04	12.48	29	17751	250981	50336363
Wound	26.65	12.48	3	17777	105791	50481553
Loss of bladder sensation	25.82	12.48	5	17775	25	50587319
Atonic urinary bladder	25.51	12.48	6	17774	84	50587260
Delirium	25.37	12.48	47	17733	38145	50549199
Hypersensitivity	25.31	12.48	23	17757	215138	50372206
Therapeutic product effect decreased	23.82	12.48	9	17771	136041	50451303
Nausea	23.36	12.48	362	17418	705036	49882308
Mental status changes	23.29	12.48	44	17736	36228	50551116
Flatulence	21.79	12.48	38	17742	29420	50557924
Prescription drug used without a prescription	21.65	12.48	11	17769	1689	50585655
Nasopharyngitis	21.09	12.48	22	17758	192905	50394439
Sinusitis	20.33	12.48	18	17762	170540	50416804
Anal sphincter atony	19.80	12.48	6	17774	229	50587115
Hyponatraemia	19.46	12.48	76	17704	96063	50491281
Subileus	19.17	12.48	12	17768	2747	50584597
Body dysmorphic disorder	19.09	12.48	6	17774	259	50587085
Hypokalaemia	18.99	12.48	71	17709	87921	50499423
Headache	18.80	12.48	103	17677	506432	50080912
Rash	18.49	12.48	85	17695	437386	50149958
Abdominal pain	18.45	12.48	144	17636	236084	50351260
Exposure during pregnancy	18.08	12.48	10	17770	121005	50466339
Mutism	17.77	12.48	9	17771	1372	50585972
Foreign body	17.40	12.48	10	17770	1961	50585383
Intestinal obstruction	16.93	12.48	32	17748	26351	50560993
Product use issue	16.38	12.48	17	17763	149458	50437886
Drug dose titration not performed	15.80	12.48	6	17774	458	50586886
Listless	15.62	12.48	10	17770	2380	50584964
Musculoskeletal stiffness	14.78	12.48	14	17766	128467	50458877
Anorgasmia	14.76	12.48	6	17774	549	50586795
Infusion related reaction	14.72	12.48	23	17757	169534	50417810
Ascites	14.41	12.48	36	17744	35825	50551519
Pericoronitis	14.28	12.48	3	17777	24	50587320
Freezing phenomenon	14.20	12.48	7	17773	1008	50586336
Pain in extremity	14.05	12.48	49	17731	272816	50314528
Reduced facial expression	13.84	12.48	8	17772	1586	50585758
Infection	13.60	12.48	25	17755	172929	50414415
Urinary tract infection	13.51	12.48	129	17651	223891	50363453
Completed suicide	13.35	12.48	16	17764	131873	50455471
Localised oedema	13.09	12.48	12	17768	4855	50582489
Psoriasis	13.05	12.48	4	17776	68996	50518348
Anticholinergic syndrome	12.96	12.48	8	17772	1787	50585557
Product appearance confusion	12.89	12.48	3	17777	40	50587304
Leukocytosis	12.81	12.48	26	17754	22553	50564791
Enteral nutrition	12.75	12.48	3	17777	42	50587302
Intestinal perforation	12.69	12.48	17	17763	10462	50576882
Lower respiratory tract infection	12.65	12.48	9	17771	95192	50492152

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Appendicolith	139.72	13.72	53	12167	3427	29558880
Victim of child abuse	99.55	13.72	29	12191	816	29561491
Appendicitis	98.27	13.72	55	12165	8724	29553583
Hyponatraemia	70.33	13.72	111	12109	67522	29494785
Respiratory depression	69.67	13.72	52	12168	13471	29548836
Cardiogenic shock	69.47	13.72	60	12160	19130	29543177
Sepsis	66.32	13.72	167	12053	142515	29419792
Abdominal distension	57.17	13.72	82	12138	45829	29516478
Stress	56.10	13.72	56	12164	21434	29540873
Constipation	53.39	13.72	134	12086	114026	29448281
Urinary tract infection	53.29	13.72	102	12118	72252	29490055
Drug dependence	44.61	13.72	49	12171	20932	29541375
Epidural lipomatosis	44.30	13.72	15	12205	696	29561611
Ascites	42.09	13.72	63	12157	36556	29525751
Multiple organ dysfunction syndrome	37.00	13.72	81	12139	63035	29499272
Product prescribing error	36.52	13.72	41	12179	17935	29544372
General physical health deterioration	35.40	13.72	108	12112	102749	29459558
Juvenile idiopathic arthritis	34.48	13.72	15	12205	1379	29560928
Urosepsis	33.71	13.72	31	12189	10715	29551592
Ventricular fibrillation	28.61	13.72	34	12186	15799	29546508
Vomiting	28.52	13.72	167	12053	212093	29350214
Sitting disability	27.36	13.72	7	12213	119	29562188
Abdominal pain	26.19	13.72	118	12102	135239	29427068
Mixed dementia	26.09	13.72	8	12212	269	29562038
Urinary retention	21.06	13.72	43	12177	31855	29530452
Quality of life decreased	20.12	13.72	14	12206	3248	29559059
Decubitus ulcer	18.97	13.72	19	12201	7292	29555015
Completed suicide	18.62	13.72	7	12213	90239	29472068
Transcription medication error	17.80	13.72	5	12215	123	29562184
Alveolar proteinosis	16.92	13.72	6	12214	320	29561987
Burkholderia test positive	16.13	13.72	8	12212	991	29561316
Nausea	15.08	13.72	184	12036	289071	29273236
Pneumonia aspiration	14.95	13.72	41	12179	36696	29525611
Convulsive threshold lowered	14.39	13.72	6	12214	497	29561810
Obesity	14.34	13.72	19	12201	9844	29552463

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Sedation complication	298.02	12.22	124	26528	10230	64461850
Cognitive disorder	251.47	12.22	197	26455	54890	64417190
Creatinine renal clearance decreased	246.51	12.22	120	26532	14301	64457779
Orthostatic hypotension	232.68	12.22	176	26476	46562	64425518
Sedation	214.99	12.22	160	26492	41302	64430778
Blood calcium decreased	199.69	12.22	127	26525	25427	64446653
Hypomania	177.25	12.22	72	26580	5582	64466498
Balance disorder	166.60	12.22	189	26463	83737	64388343
Jaundice cholestatic	159.83	12.22	76	26576	8594	64463486
Appendicolith	139.82	12.22	53	26599	3416	64468664
Schizophrenia	136.04	12.22	74	26578	11094	64460986
Mobility decreased	107.85	12.22	154	26498	85686	64386394
Constipation	101.78	12.22	264	26388	229073	64243007
Victim of child abuse	98.66	12.22	29	26623	842	64471238
Fall	97.77	12.22	385	26267	416441	64055639
Depressed level of consciousness	97.77	12.22	143	26509	81293	64390787
Psychotic disorder	97.49	12.22	94	26558	34484	64437596
Appendicitis	85.52	12.22	59	26593	13510	64458570
Hyponatraemia	79.84	12.22	184	26468	148155	64323925
Hypotension	76.01	12.22	335	26317	380639	64091441
Drug ineffective	64.70	12.22	159	26493	840088	63631992
Cholelithiasis	62.12	12.22	85	26567	45421	64426659
Ascites	59.20	12.22	98	26554	61903	64410177
Hepatotoxicity	58.14	12.22	77	26575	39885	64432195
Vomiting	57.66	12.22	407	26245	550710	63921370
Blood bilirubin increased	54.98	12.22	91	26561	57462	64414618
Abdominal distension	54.86	12.22	122	26530	95872	64376208
Intestinal pseudo-obstruction	54.34	12.22	23	26629	1977	64470103
Cardiogenic shock	54.29	12.22	67	26585	32360	64439720
Respiratory depression	50.24	12.22	55	26597	23388	64448692
Sepsis	50.03	12.22	208	26444	230133	64241947
Urinary retention	44.60	12.22	76	26576	49125	64422955
Urinary tract infection	42.59	12.22	199	26453	231397	64240683
Epidural lipomatosis	41.21	12.22	15	26637	862	64471218
Rheumatoid arthritis	38.80	12.22	10	26642	164284	64307796
Completed suicide	37.76	12.22	23	26629	224391	64247689
Nausea	37.27	12.22	491	26161	785309	63686771
Pneumonia	35.53	12.22	370	26282	559206	63912874
Abdominal pain	34.49	12.22	234	26418	312141	64159939
Arthralgia	34.43	12.22	83	26569	442177	64029903
Drug dependence	32.25	12.22	53	26599	33259	64438821
General physical health deterioration	31.42	12.22	167	26485	204258	64267822
Joint swelling	31.08	12.22	26	26626	215356	64256724
Product prescribing error	28.75	12.22	52	26600	35217	64436863
Nasopharyngitis	27.88	12.22	24	26628	196049	64276031
Ventricular fibrillation	25.90	12.22	40	26612	23820	64448260
Sitting disability	25.88	12.22	7	26645	149	64471931
Mixed dementia	25.73	12.22	8	26644	282	64471798
Alopecia	25.16	12.22	19	26633	165671	64306409
Juvenile idiopathic arthritis	24.75	12.22	17	26635	3862	64468218
Atonic urinary bladder	24.74	12.22	6	26646	81	64471999
Multiple organ dysfunction syndrome	24.71	12.22	95	26557	101318	64370762
Treatment failure	24.18	12.22	9	26643	116807	64355273
Quality of life decreased	23.47	12.22	22	26630	7784	64464296
Drug intolerance	23.27	12.22	26	26626	187966	64284114
Sinusitis	23.11	12.22	16	26636	145912	64326168
Urosepsis	22.54	12.22	36	26616	22058	64450022
Hypersensitivity	22.38	12.22	29	26623	196423	64275657
Maternal exposure during pregnancy	22.32	12.22	6	26646	95878	64376202
Decubitus ulcer	21.36	12.22	27	26625	13352	64458728
Arthropathy	20.89	12.22	12	26640	120955	64351125
Mental status changes	20.77	12.22	64	26588	61098	64410982
Loss of bladder sensation	20.45	12.22	5	26647	70	64472010
Toxicity to various agents	20.07	12.22	234	26418	363279	64108801
Systemic lupus erythematosus	19.76	12.22	4	26648	77608	64394472
Interstitial lung disease	19.45	12.22	8	26644	97724	64374356
Injection site pain	19.31	12.22	11	26641	111397	64360683
Unresponsive to stimuli	19.27	12.22	55	26597	50338	64421742
Death	18.91	12.22	292	26360	482413	63989667
Flatulence	18.88	12.22	44	26608	35622	64436458
Delirium	18.67	12.22	67	26585	69127	64402953
Stress	18.42	12.22	61	26591	60473	64411607
Body dysmorphic disorder	18.27	12.22	6	26646	253	64471827
Intentional product misuse	17.83	12.22	68	26584	72227	64399853
Small intestinal obstruction	17.02	12.22	33	26619	23540	64448540
Anal sphincter atony	16.93	12.22	6	26646	319	64471761
Colitis ischaemic	16.72	12.22	24	26628	13390	64458690
Neurogenic bladder	16.61	12.22	13	26639	3606	64468474
Transcription medication error	16.48	12.22	6	26646	345	64471735
Pain in extremity	16.39	12.22	67	26585	303018	64169062
Pericarditis	16.38	12.22	3	26649	62513	64409567
Leukocytosis	16.22	12.22	43	26609	37697	64434383
Infusion related reaction	16.07	12.22	27	26625	164440	64307640
Drug hypersensitivity	15.92	12.22	48	26604	237767	64234313
Freezing phenomenon	15.45	12.22	9	26643	1537	64470543
Tubulointerstitial nephritis	15.14	12.22	37	26615	30872	64441208
Hypokalaemia	15.05	12.22	94	26558	121809	64350271
Heparin-induced thrombocytopenia	14.97	12.22	18	26634	8461	64463619
Dementia	14.90	12.22	29	26623	20737	64451343
Exposure during pregnancy	14.45	12.22	7	26645	77668	64394412
Contraindicated product administered	14.37	12.22	14	26638	107815	64364265
Intestinal obstruction	14.26	12.22	40	26612	36246	64435834
Therapeutic product effect decreased	14.22	12.22	16	26636	115335	64356745
Lower respiratory tract infection	14.16	12.22	11	26641	94603	64377477
Pain	14.04	12.22	313	26339	553198	63918882
Headache	13.83	12.22	146	26506	529321	63942759
Alveolar proteinosis	13.56	12.22	6	26646	574	64471506
Failure to thrive	13.54	12.22	19	26633	10385	64461695
Arthritis	13.52	12.22	9	26643	83805	64388275
Prescription drug used without a prescription	13.38	12.22	10	26642	2590	64469490
Pneumonia aspiration	13.20	12.22	54	26598	59217	64412863
Mutism	13.18	12.22	9	26643	2025	64470055
Subileus	13.03	12.22	13	26639	4964	64467116
Reduced facial expression	12.87	12.22	9	26643	2104	64469976
Peripheral swelling	12.76	12.22	44	26608	209109	64262971
Rash	12.56	12.22	125	26527	458424	64013656
Psoriasis	12.54	12.22	7	26645	71696	64400384

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A06AB02	ALIMENTARY TRACT AND METABOLISM DRUGS FOR CONSTIPATION DRUGS FOR CONSTIPATION Contact laxatives
ATC	A06AB52	ALIMENTARY TRACT AND METABOLISM DRUGS FOR CONSTIPATION DRUGS FOR CONSTIPATION Contact laxatives
ATC	A06AG02	ALIMENTARY TRACT AND METABOLISM DRUGS FOR CONSTIPATION DRUGS FOR CONSTIPATION Enemas
FDA PE	N0000009371	Increased Large Intestinal Motility
FDA PE	N0000009871	Stimulation Large Intestine Fluid/Electrolyte Secretion
MeSH PA	D002400	Cathartics
MeSH PA	D005765	Gastrointestinal Agents
MeSH PA	D054368	Laxatives
FDA EPC	N0000175812	Stimulant Laxative

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Constipation	indication	14760008	DOID:2089
Incomplete passage of stool	indication	249515001
Anuria	contraindication	2472002	DOID:2983
Hypocalcemia	contraindication	5291005
Rectal hemorrhage	contraindication	12063002
Hyperkalemia	contraindication	14140009
Severe chronic ulcerative colitis	contraindication	14311001
Acute vomiting	contraindication	23971007
Complete atrioventricular block	contraindication	27885002
Toxic megacolon	contraindication	28536002	DOID:1770
Anal fissure	contraindication	30037006
Gastrointestinal ulcer	contraindication	40845000
Toxic colitis	contraindication	42359007
Hypokalemia	contraindication	43339004
Chronic heart failure	contraindication	48447003
Gastrointestinal perforation	contraindication	51875005
Chronic ulcerative proctitis	contraindication	52231000
Congenital myotonia, autosomal dominant form	contraindication	57938005
Acute nephropathy	contraindication	58574008
Incontinence of feces	contraindication	72042002
Appendicitis	contraindication	74400008	DOID:8337
Hyperchloremia	contraindication	74450001
Third degree burn injury	contraindication	80247002
Intestinal obstruction	contraindication	81060008	DOID:8437
Oliguria	contraindication	83128009
Hyponatremia	contraindication	89627008
Kidney disease	contraindication	90708001	DOID:557
Gastrointestinal obstruction	contraindication	126765001
Seizure disorder	contraindication	128613002
Hyporeninemic hypoaldosteronism	contraindication	236464008
Edema	contraindication	267038008
Familial hyperkalemic periodic paralysis	contraindication	304737009	DOID:14451
Gastric retention	contraindication	307227006
At risk for aspiration	contraindication	371736008
Severe dehydration	contraindication	450316000

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	4.39	Basic

Orange Book patent data (new drug applications)

Formulation strength	Trade name	Applicant	Application number	Approval date	Type	Dose form	Route	Patent number	Patent expiration date	Patent use
5MG,N/A;N/A,210GM;N/A,0.74GM;N/A,2.86GM;N/A,5.6GM Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	HALFLYTELY	BRAINTREE	N021551	July 16, 2010	DISCN	FOR SOLUTION, TABLET, DELAYED RELEASE	ORAL	7291324	Oct. 22, 2022	GASTROINTESTINAL LAVAGE INDICATED FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY IN ADULTS

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Type	Activity value (-log[M])	Bioact source
Sodium-dependent dopamine transporter	Transporter	Q01959	SC6A3_HUMAN	Ki	5.76	DRUG MATRIX
Kappa-type opioid receptor	GPCR	P41145	OPRK_HUMAN	Ki	6.01	DRUG MATRIX
Cytochrome P450 2C9	Enzyme	P11712	CP2C9_HUMAN	IC50	5	DRUG MATRIX

External reference:

ID	Source
4018526	VUID
N0000146848	NUI
D00245	KEGG_DRUG
151672	RXNORM
C0005632	UMLSCUI
CHEBI:3125	CHEBI
CHEMBL942	ChEMBL_ID
DB09020	DRUGBANK_ID
D001726	MESH_DESCRIPTOR_UI
2391	PUBCHEM_CID
824	INN_ID
10X0709Y6I	UNII
4286	MMSL
4855	MMSL
d01015	MMSL
001172	NDDF
13565005	SNOMEDCT_US
387075009	SNOMEDCT_US
4018526	VANDF

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Fleet	HUMAN OTC DRUG LABEL	1	0132-0703	ENEMA	10 mg	RECTAL	OTC monograph not final	11 sections
Gentle Laxative	HUMAN OTC DRUG LABEL	1	0363-0327	TABLET	5 mg	ORAL	OTC MONOGRAPH NOT FINAL	16 sections
Gentle Laxative	HUMAN OTC DRUG LABEL	1	0363-0327	TABLET	5 mg	ORAL	OTC MONOGRAPH NOT FINAL	16 sections
Walgreens Gentle Laxative	HUMAN OTC DRUG LABEL	1	0363-0466	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	14 sections
Walgreens Gentle Laxative	HUMAN OTC DRUG LABEL	1	0363-0466	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	14 sections
Walgreens Gentle Laxative	HUMAN OTC DRUG LABEL	1	0363-0466	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	14 sections
WOMENS GENTLE LAXATIVE	HUMAN OTC DRUG LABEL	1	0363-3011	CAPSULE, GELATIN COATED	5 mg	ORAL	OTC monograph not final	16 sections
Laxative	HUMAN OTC DRUG LABEL	1	0363-6760	TABLET, COATED	5 mg	ORAL	OTC monograph not final	15 sections
Rugby Gentle Laxative	HUMAN OTC DRUG LABEL	1	0536-1238	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	15 sections
ENTERIC COATED STIMULANT LAXATIVE	HUMAN OTC DRUG LABEL	1	0536-3381	TABLET, DELAYED RELEASE	5 mg	ORAL	OTC monograph not final	6 sections
Bisacodyl	HUMAN OTC DRUG LABEL	1	0574-7050	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	15 sections
Bisacodyl	HUMAN OTC DRUG LABEL	1	0615-0598	TABLET, COATED	5 mg	ORAL	OTC MONOGRAPH NOT FINAL	14 sections
Unit Dose Bisacodyl	HUMAN OTC DRUG LABEL	1	0904-6407	TABLET, DELAYED RELEASE	5 mg	ORAL	OTC monograph not final	15 sections
Bisacodyl	HUMAN OTC DRUG LABEL	1	0904-6748	TABLET, COATED	5 mg	ORAL	OTC monograph not final	15 sections
Leader Gentle Laxative	HUMAN OTC DRUG LABEL	1	0904-6981	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	15 sections
Leader Gentle Laxative	HUMAN OTC DRUG LABEL	1	0904-6981	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	15 sections
Bisacodyl	HUMAN OTC DRUG LABEL	1	0904-7142	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	14 sections
Carters Little PillsSodium-Free	HUMAN OTC DRUG LABEL	1	10237-906	TABLET, DELAYED RELEASE	5 mg	ORAL	OTC monograph not final	11 sections
Bisacodyl	HUMAN OTC DRUG LABEL	1	11534-013	TABLET, DELAYED RELEASE	5 mg	ORAL	OTC monograph not final	13 sections
Bisacodyl	HUMAN OTC DRUG LABEL	1	11534-156	TABLET, DELAYED RELEASE	5 mg	ORAL	OTC monograph not final	12 sections
LaxativeEnteric Coated	HUMAN OTC DRUG LABEL	1	11673-053	TABLET, COATED	5 mg	ORAL	OTC MONOGRAPH NOT FINAL	15 sections
up and up gentle laxative	HUMAN OTC DRUG LABEL	1	11673-116	TABLET, COATED	5 mg	ORAL	OTC monograph not final	15 sections
WOMENS GENTLE LAXATIVE	HUMAN OTC DRUG LABEL	1	11673-151	TABLET	5 mg	ORAL	OTC monograph not final	8 sections
BISACODYL	HUMAN OTC DRUG LABEL	1	11673-182	TABLET, COATED	5 mg	ORAL	OTC monograph not final	7 sections
Laxative	HUMAN OTC DRUG LABEL	1	11822-0327	TABLET, DELAYED RELEASE	5 mg	ORAL	OTC monograph not final	15 sections
laxative for women	HUMAN OTC DRUG LABEL	1	11822-0676	TABLET, COATED	5 mg	ORAL	OTC monograph not final	15 sections
Rite Aid fast relief laxative	HUMAN OTC DRUG LABEL	1	11822-4600	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	13 sections
Rite Aid fast relief laxative	HUMAN OTC DRUG LABEL	1	11822-4601	SUPPOSITORY	10 mg	RECTAL	OTC monograph not final	12 sections
DELAYED RELEASE LAXATIVE BISACODYL	HUMAN OTC DRUG LABEL	1	11822-7850	TABLET, DELAYED RELEASE	5 mg	ORAL	OTC monograph not final	15 sections
Bisacodyl	HUMAN OTC DRUG LABEL	1	16103-367	TABLET, DELAYED RELEASE	5 mg	ORAL	OTC monograph not final	15 sections