Explore drug properties, targets, and indications with answers grounded in DrugCentral.
Powered by DrugCentral + retrieval-augmented AIAsk in your own words. Each question is answered independently.
Select a question to fill the editor, then ask it or make it your own.
Your answer will appear here. Open linked drug cards in a new tab to explore the source details.
Ask DrugCentral helps you explore drug properties, biological targets, and indications using natural language. Sample questions offer starting points, and linked drug cards let you check the underlying records.
Each request is independent; previous questions are not sent as conversation history. You can edit a sample before submitting, retry a failed request, or switch back to normal search. Drug links open in a new tab so your question and answer stay available.
Answers may contain mistakes or omit information. Verify details against DrugCentral records and original sources.
AI can make mistakes. Verify answers against the original sources before relying on them.
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4779 | 10040-45-6 |
| Molecule | Description |
|---|---|
|
Synonyms:
|
contains two active ingredients, sodium picosulfate and magnesium citrate, which are both laxatives; structure
|
| Dose | Unit | Route |
|---|---|---|
| 5 | mg | O |
None
None
| Date | Agency | Company | Orphan |
|---|---|---|---|
| July 16, 2012 | FDA | FERRING PHARMS AS |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Food allergy | 457.96 | 22.45 | 165 | 13691 | 25313 | 90589278 |
| Immunodeficiency | 379.86 | 22.45 | 167 | 13689 | 43067 | 90571524 |
| Overdose | 337.31 | 22.45 | 240 | 13616 | 157469 | 90457122 |
| Intentional product misuse | 313.94 | 22.45 | 186 | 13670 | 89418 | 90525173 |
| Temperature regulation disorder | 267.78 | 22.45 | 96 | 13760 | 14483 | 90600108 |
| Prescribed overdose | 249.63 | 22.45 | 166 | 13690 | 97459 | 90517132 |
| Hyperhidrosis | 249.59 | 22.45 | 189 | 13667 | 136116 | 90478475 |
| Foetal death | 218.00 | 22.45 | 91 | 13765 | 20632 | 90593959 |
| Exposure during pregnancy | 138.28 | 22.45 | 176 | 13680 | 238234 | 90376357 |
| Cognitive disorder | 115.40 | 22.45 | 91 | 13765 | 69316 | 90545275 |
| Fluid retention | 114.22 | 22.45 | 100 | 13756 | 87991 | 90526600 |
| Creatinine renal clearance increased | 109.90 | 22.45 | 34 | 13822 | 3247 | 90611344 |
| Hypertension | 107.52 | 22.45 | 224 | 13632 | 457308 | 90157283 |
| Hyponatraemia | 102.80 | 22.45 | 114 | 13742 | 133424 | 90481167 |
| Renal function test abnormal | 101.33 | 22.45 | 39 | 13817 | 7152 | 90607439 |
| Reduced facial expression | 96.35 | 22.45 | 29 | 13827 | 2524 | 90612067 |
| Listless | 93.56 | 22.45 | 30 | 13826 | 3219 | 90611372 |
| Creatinine renal clearance decreased | 92.67 | 22.45 | 49 | 13807 | 18850 | 90595741 |
| Product use issue | 92.45 | 22.45 | 174 | 13682 | 329745 | 90284846 |
| Hepatic enzyme increased | 92.24 | 22.45 | 183 | 13673 | 360553 | 90254038 |
| Sedation complication | 88.99 | 22.45 | 46 | 13810 | 16898 | 90597693 |
| Urinary retention | 84.03 | 22.45 | 59 | 13797 | 37685 | 90576906 |
| Rash erythematous | 82.55 | 22.45 | 73 | 13783 | 65031 | 90549560 |
| Constipation | 82.42 | 22.45 | 151 | 13705 | 280244 | 90334347 |
| Coeliac disease | 81.78 | 22.45 | 62 | 13794 | 44548 | 90570043 |
| Multiple drug therapy | 77.80 | 22.45 | 32 | 13824 | 6977 | 90607614 |
| Apathy | 72.84 | 22.45 | 35 | 13821 | 11005 | 90603586 |
| Decreased immune responsiveness | 67.81 | 22.45 | 31 | 13825 | 8717 | 90605874 |
| Psoriasis | 67.14 | 22.45 | 97 | 13759 | 147657 | 90466934 |
| Blood calcium decreased | 66.76 | 22.45 | 47 | 13809 | 30135 | 90584456 |
| Cholestatic liver injury | 65.93 | 22.45 | 24 | 13832 | 3773 | 90610818 |
| Ileus | 62.17 | 22.45 | 36 | 13820 | 16510 | 90598081 |
| Orthostatic hypotension | 61.36 | 22.45 | 51 | 13805 | 41776 | 90572815 |
| Thrombocytopenia | 58.26 | 22.45 | 110 | 13746 | 208615 | 90405976 |
| Infusion related reaction | 58.01 | 22.45 | 167 | 13689 | 416613 | 90197978 |
| Depressed level of consciousness | 55.72 | 22.45 | 62 | 13794 | 72722 | 90541869 |
| Hypersensitivity | 55.56 | 22.45 | 174 | 13682 | 454503 | 90160088 |
| Sedation | 55.13 | 22.45 | 51 | 13805 | 48120 | 90566471 |
| Head discomfort | 54.72 | 22.45 | 33 | 13823 | 16300 | 90598291 |
| Off label use | 53.27 | 22.45 | 318 | 13538 | 1101934 | 89512657 |
| Drug interaction | 53.06 | 22.45 | 125 | 13731 | 276328 | 90338263 |
| Upper respiratory tract infection | 52.20 | 22.45 | 80 | 13776 | 128238 | 90486353 |
| Foreign body | 51.77 | 22.45 | 18 | 13838 | 2476 | 90612115 |
| Altered state of consciousness | 49.50 | 22.45 | 40 | 13816 | 31492 | 90583099 |
| Immobile | 47.48 | 22.45 | 22 | 13834 | 6376 | 90608215 |
| Prescription drug used without a prescription | 47.10 | 22.45 | 18 | 13838 | 3237 | 90611354 |
| Hypokalaemia | 46.79 | 22.45 | 77 | 13779 | 131039 | 90483552 |
| Pyrexia | 45.91 | 22.45 | 211 | 13645 | 660274 | 89954317 |
| Peripheral swelling | 45.60 | 22.45 | 5 | 13851 | 413101 | 90201490 |
| Arthralgia | 43.96 | 22.45 | 33 | 13823 | 778489 | 89836102 |
| Alopecia | 43.63 | 22.45 | 11 | 13845 | 495060 | 90119531 |
| Drug abuse | 43.26 | 22.45 | 58 | 13798 | 82289 | 90532302 |
| Abdominal discomfort | 41.30 | 22.45 | 11 | 13845 | 477317 | 90137274 |
| Sinusitis | 40.96 | 22.45 | 3 | 13853 | 343085 | 90271506 |
| Joint swelling | 40.43 | 22.45 | 168 | 13688 | 503132 | 90111459 |
| Affect lability | 37.34 | 22.45 | 27 | 13829 | 18036 | 90596555 |
| General physical health deterioration | 37.14 | 22.45 | 129 | 13727 | 354986 | 90259605 |
| Product prescribing error | 36.60 | 22.45 | 33 | 13823 | 30112 | 90584479 |
| Swelling | 35.60 | 22.45 | 10 | 13846 | 419048 | 90195543 |
| Inappropriate antidiuretic hormone secretion | 35.49 | 22.45 | 27 | 13829 | 19478 | 90595113 |
| Drug ineffective | 34.90 | 22.45 | 103 | 13753 | 1384195 | 89230396 |
| Fracture | 34.64 | 22.45 | 28 | 13828 | 22048 | 90592543 |
| Dehydration | 34.14 | 22.45 | 85 | 13771 | 194362 | 90420229 |
| Weight increased | 33.64 | 22.45 | 11 | 13845 | 417916 | 90196675 |
| Nasopharyngitis | 32.27 | 22.45 | 11 | 13845 | 407093 | 90207498 |
| Pelvic fracture | 32.04 | 22.45 | 23 | 13833 | 15196 | 90599395 |
| Balance disorder | 31.94 | 22.45 | 55 | 13801 | 97025 | 90517566 |
| Delirium | 30.33 | 22.45 | 56 | 13800 | 104303 | 90510288 |
| Bursitis | 29.08 | 22.45 | 63 | 13793 | 131591 | 90483000 |
| Restlessness | 28.31 | 22.45 | 31 | 13825 | 35689 | 90578902 |
| Encephalopathy | 27.96 | 22.45 | 35 | 13821 | 46409 | 90568182 |
| Oxygen saturation decreased | 27.93 | 22.45 | 55 | 13801 | 107428 | 90507163 |
| Abdominal rigidity | 26.29 | 22.45 | 11 | 13845 | 2501 | 90612090 |
| Blister | 25.92 | 22.45 | 4 | 13852 | 254994 | 90359597 |
| Paraesthesia | 25.28 | 22.45 | 4 | 13852 | 250322 | 90364269 |
| Electrolyte imbalance | 24.98 | 22.45 | 24 | 13832 | 23721 | 90590870 |
| Bedridden | 24.75 | 22.45 | 18 | 13838 | 12130 | 90602461 |
| Psoriatic arthropathy | 24.58 | 22.45 | 3 | 13853 | 228332 | 90386259 |
| Pruritus | 24.55 | 22.45 | 28 | 13828 | 541497 | 90073094 |
| Fall | 24.37 | 22.45 | 141 | 13715 | 481669 | 90132922 |
| Depression | 24.02 | 22.45 | 8 | 13848 | 300593 | 90313998 |
| Asthenia | 23.76 | 22.45 | 28 | 13828 | 533723 | 90080868 |
| Retching | 23.31 | 22.45 | 21 | 13835 | 19138 | 90595453 |
| Chest pain | 23.06 | 22.45 | 10 | 13846 | 319635 | 90294956 |
| Product dose omission issue | 22.90 | 22.45 | 8 | 13848 | 291679 | 90322912 |
| Paraneoplastic rash | 22.55 | 22.45 | 5 | 13851 | 128 | 90614463 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Appendicolith | 437.31 | 19.43 | 163 | 13241 | 13293 | 42594638 |
| Appendicitis | 389.54 | 19.43 | 169 | 13235 | 20444 | 42587487 |
| Blood phosphorus increased | 308.20 | 19.43 | 124 | 13280 | 12401 | 42595530 |
| Ventricular fibrillation | 302.59 | 19.43 | 160 | 13244 | 29963 | 42577968 |
| General physical health deterioration | 280.39 | 19.43 | 288 | 13116 | 150958 | 42456973 |
| Cardiogenic shock | 280.07 | 19.43 | 161 | 13243 | 35479 | 42572452 |
| Abdominal distension | 260.17 | 19.43 | 200 | 13204 | 71535 | 42536396 |
| Ascites | 243.49 | 19.43 | 175 | 13229 | 56503 | 42551428 |
| Stress | 243.13 | 19.43 | 159 | 13245 | 44053 | 42563878 |
| Myasthenia gravis | 206.49 | 19.43 | 101 | 13303 | 16036 | 42591895 |
| Hyponatraemia | 201.91 | 19.43 | 201 | 13203 | 101261 | 42506670 |
| Blood uric acid increased | 186.11 | 19.43 | 93 | 13311 | 15454 | 42592477 |
| Multiple organ dysfunction syndrome | 170.80 | 19.43 | 180 | 13224 | 96855 | 42511076 |
| Dry mouth | 168.54 | 19.43 | 122 | 13282 | 39757 | 42568174 |
| Hyperphosphataemia | 168.17 | 19.43 | 82 | 13322 | 12922 | 42595009 |
| Blood cholesterol increased | 156.30 | 19.43 | 100 | 13304 | 26641 | 42581290 |
| Incorrect route of product administration | 144.80 | 19.43 | 92 | 13312 | 24213 | 42583718 |
| Abdominal pain | 144.52 | 19.43 | 233 | 13171 | 190238 | 42417693 |
| Constipation | 136.19 | 19.43 | 208 | 13196 | 162083 | 42445848 |
| Iron deficiency | 131.87 | 19.43 | 66 | 13338 | 10995 | 42596936 |
| Hypophosphataemia | 131.57 | 19.43 | 82 | 13322 | 20863 | 42587068 |
| Bacterial infection | 130.94 | 19.43 | 91 | 13313 | 27788 | 42580143 |
| Sleep disorder therapy | 128.36 | 19.43 | 56 | 13348 | 6838 | 42601093 |
| Neuralgia | 123.46 | 19.43 | 85 | 13319 | 25562 | 42582369 |
| Drug therapy | 116.11 | 19.43 | 51 | 13353 | 6329 | 42601602 |
| Diabetes mellitus | 104.74 | 19.43 | 111 | 13293 | 59976 | 42547955 |
| Sepsis | 96.60 | 19.43 | 201 | 13203 | 199133 | 42408798 |
| Somnolence | 92.67 | 19.43 | 162 | 13242 | 140943 | 42466988 |
| Vomiting | 91.36 | 19.43 | 247 | 13157 | 289476 | 42318455 |
| Swelling | 74.43 | 19.43 | 89 | 13315 | 54796 | 42553135 |
| Thrombosis | 66.21 | 19.43 | 94 | 13310 | 68417 | 42539514 |
| Chronic obstructive pulmonary disease | 66.08 | 19.43 | 90 | 13314 | 63024 | 42544907 |
| Intentional product misuse | 65.92 | 19.43 | 89 | 13315 | 61811 | 42546120 |
| Antacid therapy | 64.74 | 19.43 | 31 | 13373 | 4686 | 42603245 |
| Aortic stenosis | 64.58 | 19.43 | 38 | 13366 | 8707 | 42599224 |
| Nausea | 63.19 | 19.43 | 269 | 13135 | 396530 | 42211401 |
| Sleep disorder | 61.96 | 19.43 | 76 | 13328 | 48019 | 42559912 |
| Bacteroides infection | 61.47 | 19.43 | 25 | 13379 | 2562 | 42605369 |
| Anticoagulant therapy | 56.81 | 19.43 | 28 | 13376 | 4507 | 42603424 |
| Drug intolerance | 56.19 | 19.43 | 95 | 13309 | 80329 | 42527602 |
| Drug ineffective | 54.92 | 19.43 | 71 | 13333 | 630126 | 41977805 |
| Activated partial thromboplastin time prolonged | 54.57 | 19.43 | 43 | 13361 | 15860 | 42592071 |
| End stage renal disease | 50.94 | 19.43 | 42 | 13362 | 16516 | 42591415 |
| Ulcer | 49.11 | 19.43 | 41 | 13363 | 16400 | 42591531 |
| Anaemia | 47.61 | 19.43 | 194 | 13210 | 280084 | 42327847 |
| Drug hypersensitivity | 42.02 | 19.43 | 95 | 13309 | 99294 | 42508637 |
| Dehiscence | 41.27 | 19.43 | 13 | 13391 | 633 | 42607298 |
| Total lung capacity decreased | 38.74 | 19.43 | 20 | 13384 | 3550 | 42604381 |
| Fatigue | 35.89 | 19.43 | 51 | 13353 | 435590 | 42172341 |
| Pulmonary embolism | 34.56 | 19.43 | 99 | 13305 | 119513 | 42488418 |
| Hyperlipidaemia | 34.38 | 19.43 | 38 | 13366 | 21478 | 42586453 |
| Troponin increased | 32.78 | 19.43 | 35 | 13369 | 19027 | 42588904 |
| Gout | 32.40 | 19.43 | 42 | 13362 | 28013 | 42579918 |
| Blood calcium increased | 31.48 | 19.43 | 24 | 13380 | 8430 | 42599501 |
| Lung opacity | 27.25 | 19.43 | 19 | 13385 | 5818 | 42602113 |
| Rash | 26.33 | 19.43 | 29 | 13375 | 276925 | 42331006 |
| Toxicity to various agents | 25.27 | 19.43 | 21 | 13383 | 229115 | 42378816 |
| Condition aggravated | 25.25 | 19.43 | 154 | 13250 | 260600 | 42347331 |
| Arthralgia | 24.95 | 19.43 | 17 | 13387 | 205221 | 42402710 |
| Cholestatic liver injury | 24.49 | 19.43 | 15 | 13389 | 3694 | 42604237 |
| Abdominal neoplasm | 24.25 | 19.43 | 8 | 13396 | 452 | 42607479 |
| Ileus | 24.23 | 19.43 | 30 | 13374 | 19109 | 42588822 |
| Bronchopulmonary aspergillosis allergic | 23.91 | 19.43 | 16 | 13388 | 4582 | 42603349 |
| Analgesic therapy | 23.15 | 19.43 | 18 | 13386 | 6506 | 42601425 |
| Blood test abnormal | 22.73 | 19.43 | 24 | 13380 | 12882 | 42595049 |
| Neuropathy peripheral | 19.74 | 19.43 | 4 | 13400 | 101849 | 42506082 |
| Faecaloma | 19.48 | 19.43 | 16 | 13388 | 6254 | 42601677 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Appendicolith | 498.20 | 19.75 | 169 | 25713 | 14086 | 110549331 |
| Appendicitis | 427.25 | 19.75 | 182 | 25700 | 28282 | 110535135 |
| Blood phosphorus increased | 336.07 | 19.75 | 131 | 25751 | 16209 | 110547208 |
| Ventricular fibrillation | 321.81 | 19.75 | 168 | 25714 | 41145 | 110522272 |
| Hyponatraemia | 294.85 | 19.75 | 306 | 25576 | 217347 | 110346070 |
| Ascites | 282.06 | 19.75 | 207 | 25675 | 92601 | 110470816 |
| Cardiogenic shock | 270.46 | 19.75 | 168 | 25714 | 57170 | 110506247 |
| General physical health deterioration | 257.68 | 19.75 | 400 | 25482 | 424895 | 110138522 |
| Constipation | 229.97 | 19.75 | 346 | 25536 | 357440 | 110205977 |
| Myasthenia gravis | 228.35 | 19.75 | 108 | 25774 | 21403 | 110542014 |
| Blood uric acid increased | 207.01 | 19.75 | 101 | 25781 | 21428 | 110541989 |
| Abdominal distension | 199.81 | 19.75 | 225 | 25657 | 174878 | 110388539 |
| Hyperphosphataemia | 198.01 | 19.75 | 90 | 25792 | 16291 | 110547126 |
| Multiple organ dysfunction syndrome | 176.57 | 19.75 | 197 | 25685 | 151513 | 110411904 |
| Stress | 175.60 | 19.75 | 166 | 25716 | 105182 | 110458235 |
| Intentional product misuse | 174.63 | 19.75 | 184 | 25698 | 132720 | 110430697 |
| Sleep disorder therapy | 164.64 | 19.75 | 63 | 25819 | 7408 | 110556009 |
| Hypophosphataemia | 153.32 | 19.75 | 96 | 25786 | 33086 | 110530331 |
| Drug therapy | 151.82 | 19.75 | 59 | 25823 | 7232 | 110556185 |
| Iron deficiency | 137.73 | 19.75 | 73 | 25809 | 18403 | 110545014 |
| Temperature regulation disorder | 134.89 | 19.75 | 64 | 25818 | 12762 | 110550655 |
| Bacterial infection | 133.73 | 19.75 | 100 | 25782 | 45936 | 110517481 |
| Sepsis | 130.08 | 19.75 | 256 | 25626 | 327090 | 110236327 |
| Neuralgia | 116.24 | 19.75 | 94 | 25788 | 48384 | 110515033 |
| Diabetes mellitus | 113.76 | 19.75 | 128 | 25754 | 99253 | 110464164 |
| Food allergy | 113.56 | 19.75 | 66 | 25816 | 19882 | 110543535 |
| Foetal death | 112.87 | 19.75 | 61 | 25821 | 15984 | 110547433 |
| Abdominal pain | 111.60 | 19.75 | 317 | 25565 | 512672 | 110050745 |
| Incorrect route of product administration | 104.89 | 19.75 | 100 | 25782 | 63961 | 110499456 |
| Somnolence | 104.36 | 19.75 | 221 | 25661 | 297228 | 110266189 |
| Creatinine renal clearance increased | 92.36 | 19.75 | 34 | 25848 | 3591 | 110559826 |
| Antacid therapy | 88.68 | 19.75 | 37 | 25845 | 5447 | 110557970 |
| Anticoagulant therapy | 79.46 | 19.75 | 34 | 25848 | 5327 | 110558090 |
| Ileus | 78.81 | 19.75 | 62 | 25820 | 30667 | 110532750 |
| Altered state of consciousness | 77.79 | 19.75 | 81 | 25801 | 57545 | 110505872 |
| Renal function test abnormal | 77.18 | 19.75 | 39 | 25843 | 8907 | 110554510 |
| Aortic stenosis | 76.44 | 19.75 | 44 | 25838 | 13015 | 110550402 |
| Vomiting | 76.15 | 19.75 | 416 | 25466 | 910259 | 109653158 |
| Immunodeficiency | 75.99 | 19.75 | 67 | 25815 | 38771 | 110524646 |
| Cholestatic liver injury | 75.10 | 19.75 | 36 | 25846 | 7340 | 110556077 |
| Anaemia | 74.82 | 19.75 | 289 | 25593 | 546797 | 110016620 |
| Urinary retention | 68.45 | 19.75 | 83 | 25799 | 69600 | 110493817 |
| Head discomfort | 68.31 | 19.75 | 47 | 25835 | 18953 | 110544464 |
| Listless | 68.13 | 19.75 | 29 | 25853 | 4486 | 110558931 |
| Activated partial thromboplastin time prolonged | 68.11 | 19.75 | 50 | 25832 | 22318 | 110541099 |
| Reduced facial expression | 67.10 | 19.75 | 27 | 25855 | 3624 | 110559793 |
| Creatinine renal clearance decreased | 66.96 | 19.75 | 49 | 25833 | 21766 | 110541651 |
| Bacteroides infection | 65.69 | 19.75 | 25 | 25857 | 2894 | 110560523 |
| End stage renal disease | 65.38 | 19.75 | 48 | 25834 | 21425 | 110541992 |
| Thrombosis | 65.22 | 19.75 | 102 | 25780 | 108560 | 110454857 |
| Sedation complication | 64.13 | 19.75 | 46 | 25836 | 19809 | 110543608 |
| Peripheral swelling | 62.23 | 19.75 | 10 | 25872 | 404024 | 110159393 |
| Drug ineffective | 61.70 | 19.75 | 169 | 25713 | 1520371 | 109043046 |
| Chronic obstructive pulmonary disease | 60.76 | 19.75 | 99 | 25783 | 109059 | 110454358 |
| Multiple drug therapy | 60.67 | 19.75 | 32 | 25850 | 7982 | 110555435 |
| Cognitive disorder | 59.41 | 19.75 | 87 | 25795 | 87424 | 110475993 |
| Sinusitis | 57.10 | 19.75 | 3 | 25879 | 296685 | 110266732 |
| Coeliac disease | 57.02 | 19.75 | 60 | 25822 | 43127 | 110520290 |
| Nausea | 56.24 | 19.75 | 486 | 25396 | 1235204 | 109328213 |
| Overdose | 56.16 | 19.75 | 150 | 25732 | 233644 | 110329773 |
| Arthralgia | 54.91 | 19.75 | 61 | 25821 | 779571 | 109783846 |
| Decreased immune responsiveness | 52.60 | 19.75 | 31 | 25851 | 9575 | 110553842 |
| Dry mouth | 49.76 | 19.75 | 130 | 25752 | 199818 | 110363599 |
| Apathy | 48.76 | 19.75 | 36 | 25846 | 16203 | 110547214 |
| Weight increased | 48.12 | 19.75 | 19 | 25863 | 419625 | 110143792 |
| Blood calcium decreased | 47.68 | 19.75 | 50 | 25832 | 35795 | 110527622 |
| Total lung capacity decreased | 47.13 | 19.75 | 26 | 25856 | 7088 | 110556329 |
| Abdominal discomfort | 46.55 | 19.75 | 17 | 25865 | 393841 | 110169576 |
| Therapeutic product effect decreased | 45.39 | 19.75 | 3 | 25879 | 244313 | 110319104 |
| Alopecia | 44.38 | 19.75 | 15 | 25867 | 364738 | 110198679 |
| Gout | 43.36 | 19.75 | 48 | 25834 | 36518 | 110526899 |
| Pyrexia | 43.23 | 19.75 | 358 | 25524 | 897907 | 109665510 |
| Paraesthesia | 42.21 | 19.75 | 7 | 25875 | 276514 | 110286903 |
| Upper respiratory tract infection | 41.89 | 19.75 | 94 | 25788 | 131234 | 110432183 |
| Amaurosis fugax | 41.61 | 19.75 | 17 | 25865 | 2373 | 110561044 |
| Hyperlipidaemia | 40.69 | 19.75 | 46 | 25836 | 35802 | 110527615 |
| Troponin increased | 40.45 | 19.75 | 42 | 25840 | 29724 | 110533693 |
| Prescribed overdose | 40.27 | 19.75 | 73 | 25809 | 87508 | 110475909 |
| Hypokalaemia | 39.77 | 19.75 | 113 | 25769 | 182335 | 110381082 |
| Dehiscence | 38.75 | 19.75 | 12 | 25870 | 746 | 110562671 |
| Foreign body | 37.91 | 19.75 | 17 | 25865 | 2978 | 110560439 |
| Immobile | 37.38 | 19.75 | 23 | 25859 | 7679 | 110555738 |
| Rash erythematous | 37.36 | 19.75 | 68 | 25814 | 81764 | 110481653 |
| Ulcer | 36.98 | 19.75 | 48 | 25834 | 43068 | 110520349 |
| Depressed level of consciousness | 35.40 | 19.75 | 80 | 25802 | 112198 | 110451219 |
| Orthostatic hypotension | 35.39 | 19.75 | 59 | 25823 | 66190 | 110497227 |
| Memory impairment | 34.93 | 19.75 | 3 | 25879 | 196941 | 110366476 |
| Psoriatic arthropathy | 34.89 | 19.75 | 3 | 25879 | 196758 | 110366659 |
| Blood cholesterol increased | 34.17 | 19.75 | 108 | 25774 | 184677 | 110378740 |
| Fluid retention | 34.07 | 19.75 | 71 | 25811 | 94236 | 110469181 |
| Pain in extremity | 33.28 | 19.75 | 39 | 25843 | 487079 | 110076338 |
| Lung opacity | 33.13 | 19.75 | 25 | 25857 | 11627 | 110551790 |
| Blood calcium increased | 33.06 | 19.75 | 30 | 25852 | 18010 | 110545407 |
| Urinary tract disorder | 32.37 | 19.75 | 19 | 25863 | 5825 | 110557592 |
| Pulmonary embolism | 31.45 | 19.75 | 116 | 25766 | 214358 | 110349059 |
| Sleep disorder | 31.31 | 19.75 | 110 | 25772 | 198534 | 110364883 |
| Blister | 30.10 | 19.75 | 8 | 25874 | 227368 | 110336049 |
| Faecaloma | 29.72 | 19.75 | 26 | 25856 | 14882 | 110548535 |
| Depression | 29.43 | 19.75 | 19 | 25863 | 317316 | 110246101 |
| Drug interaction | 29.37 | 19.75 | 209 | 25673 | 499974 | 110063443 |
| Analgesic therapy | 28.52 | 19.75 | 19 | 25863 | 7265 | 110556152 |
| Prescription drug used without a prescription | 28.18 | 19.75 | 17 | 25865 | 5479 | 110557938 |
| Inappropriate antidiuretic hormone secretion | 27.96 | 19.75 | 37 | 25845 | 33814 | 110529603 |
| Malaise | 27.60 | 19.75 | 74 | 25808 | 671745 | 109891672 |
| Therapeutic product effect incomplete | 27.56 | 19.75 | 9 | 25873 | 223796 | 110339621 |
| Musculoskeletal pain | 27.12 | 19.75 | 5 | 25877 | 183018 | 110380399 |
| Urticaria | 27.05 | 19.75 | 21 | 25861 | 318836 | 110244581 |
| Chest pain | 26.93 | 19.75 | 29 | 25853 | 376346 | 110187071 |
| Delirium | 26.89 | 19.75 | 81 | 25801 | 134944 | 110428473 |
| Fatigue | 26.73 | 19.75 | 171 | 25711 | 1215787 | 109347630 |
| Nasopharyngitis | 26.47 | 19.75 | 32 | 25850 | 394329 | 110169088 |
| Therapy non-responder | 26.32 | 19.75 | 3 | 25879 | 157304 | 110406113 |
| Product dose omission issue | 26.29 | 19.75 | 22 | 25860 | 321760 | 110241657 |
| Folliculitis | 26.13 | 19.75 | 4 | 25878 | 167649 | 110395768 |
| Wheezing | 25.46 | 19.75 | 14 | 25868 | 255216 | 110308201 |
| Osteoarthritis | 24.99 | 19.75 | 6 | 25876 | 182617 | 110380800 |
| Affect lability | 24.79 | 19.75 | 26 | 25856 | 18611 | 110544806 |
| Sedation | 24.63 | 19.75 | 52 | 25830 | 69631 | 110493786 |
| Pneumonia aspiration | 24.63 | 19.75 | 57 | 25825 | 81176 | 110482241 |
| Injection site pain | 24.04 | 19.75 | 6 | 25876 | 177916 | 110385501 |
| Arthritis | 23.95 | 19.75 | 5 | 25877 | 167581 | 110395836 |
| Ill-defined disorder | 23.86 | 19.75 | 4 | 25878 | 156849 | 110406568 |
| Hypoaesthesia | 23.86 | 19.75 | 23 | 25859 | 314200 | 110249217 |
| Bronchopulmonary aspergillosis allergic | 23.78 | 19.75 | 18 | 25864 | 8408 | 110555009 |
| Congenital hiatus hernia | 23.72 | 19.75 | 16 | 25866 | 6243 | 110557174 |
| Benign prostatic hyperplasia | 23.47 | 19.75 | 25 | 25857 | 18209 | 110545208 |
| pH body fluid increased | 23.08 | 19.75 | 5 | 25877 | 73 | 110563344 |
| Pelvic fracture | 22.97 | 19.75 | 22 | 25860 | 14132 | 110549285 |
| Thrombocytopenia | 22.97 | 19.75 | 150 | 25732 | 348735 | 110214682 |
| Dyspepsia | 22.96 | 19.75 | 8 | 25874 | 190957 | 110372460 |
| Intentional product use issue | 22.76 | 19.75 | 15 | 25867 | 247891 | 110315526 |
| Product prescribing error | 22.60 | 19.75 | 42 | 25840 | 51289 | 110512128 |
| Pruritus | 22.43 | 19.75 | 66 | 25816 | 581494 | 109981923 |
| Drug intolerance | 22.20 | 19.75 | 167 | 25715 | 406345 | 110157072 |
| Fall | 22.09 | 19.75 | 227 | 25655 | 603255 | 109960162 |
| Fracture | 21.89 | 19.75 | 28 | 25854 | 24760 | 110538657 |
| Blood test abnormal | 21.74 | 19.75 | 30 | 25852 | 28524 | 110534893 |
| Hyperhidrosis | 21.59 | 19.75 | 94 | 25788 | 187204 | 110376213 |
| Liver function test increased | 21.42 | 19.75 | 57 | 25825 | 88491 | 110474926 |
| Systemic infection | 21.35 | 19.75 | 18 | 25864 | 9801 | 110553616 |
| Heart rate increased | 21.16 | 19.75 | 4 | 25878 | 143830 | 110419587 |
| Asthenia | 20.68 | 19.75 | 87 | 25795 | 688912 | 109874505 |
| Abdominal rigidity | 20.48 | 19.75 | 12 | 25870 | 3668 | 110559749 |
| Gait disturbance | 20.39 | 19.75 | 21 | 25861 | 278187 | 110285230 |
| Hepatic function abnormal | 20.12 | 19.75 | 56 | 25826 | 89239 | 110474178 |
| Maternal exposure during pregnancy | 20.12 | 19.75 | 18 | 25864 | 254865 | 110308552 |
None
| Source | Code | Description |
|---|---|---|
| ATC | A06AB08 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR CONSTIPATION DRUGS FOR CONSTIPATION Contact laxatives |
| ATC | A06AB58 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR CONSTIPATION DRUGS FOR CONSTIPATION Contact laxatives |
| MeSH PA | D002400 | Cathartics |
| MeSH PA | D005765 | Gastrointestinal Agents |
| CHEBI has role | CHEBI:50503 | laxative |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Colonoscopy | indication | 73761001 |
None
None
None
| Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
|---|---|---|---|---|---|---|---|---|---|---|
| 12GM/BOT;3.5GM/BOT;10MG/BOT | CLENPIQ | FERRING PHARMS INC | N209589 | Nov. 28, 2017 | RX | SOLUTION | ORAL | 11191753 | June 23, 2034 | FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY |
| 12GM/BOT;3.5GM/BOT;10MG/BOT | CLENPIQ | FERRING PHARMS INC | N209589 | Nov. 28, 2017 | RX | SOLUTION | ORAL | 12576072 | June 23, 2034 | FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY |
| 12GM/BOT;3.5GM/BOT;10MG/BOT | CLENPIQ | FERRING PHARMS INC | N209589 | Nov. 28, 2017 | RX | SOLUTION | ORAL | 9827231 | June 26, 2034 | FOR CLEANSING THE LARGE INTESTINE AS A PREPARATION FOR COLONOSCOPY |
None
None
| ID | Source |
|---|---|
| LR57574HN8 | UNII |
| 4032318 | VUID |
| N0000186955 | NUI |
| 4032318 | VANDF |
| C0071042 | UMLSCUI |
| CHEBI:32147 | CHEBI |
| CHEMBL1697768 | ChEMBL_ID |
| 68654 | PUBCHEM_CID |
| C005701 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB14232 | DRUGBANK_ID |
| 33688 | RXNORM |
| 18056 | MMSL |
| d04939 | MMSL |
| 003762 | NDDF |
| 317558003 | SNOMEDCT_US |
| 395881001 | SNOMEDCT_US |
| C0058139 | UMLSCUI |
| 69046 | PUBCHEM_CID |
| 1307301-38-7 | SECONDARY_CAS_RN |
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| SODIUM PICOSULFATE, MAGNESIUM OXIDE AND ANHYDROUS CITRIC ACID | HUMAN PRESCRIPTION DRUG LABEL | 3 | 31722-874 | POWDER, METERED | 10 mg | ORAL | ANDA | 25 sections |
| CLENPIQ | HUMAN PRESCRIPTION DRUG LABEL | 3 | 55566-6800 | LIQUID | 10 mg | ORAL | NDA | 31 sections |