iron 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4277 7439-89-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • iron
  • elemental iron (as carbonyl iron)
A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
  • Molecular weight: 55.85
  • Formula: Fe
  • CLOGP: -1.32
  • LIPINSKI: None
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS:
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,ERBB2,GRK2,GSK3B,ITK,MAP2K6,MAP3K7,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIK3CD,PIK3CG,PRKDC,STK33,SYK,TEK 30
kinase-selectivity-class PDK1 1
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hand deformity 292.48 9.86 7 99639 296355 90232446
Glossodynia 279.80 9.86 19 99627 321760 90207041
Pericarditis 250.19 9.86 11 99635 270140 90258661
Helicobacter infection 221.36 9.86 6 99640 226844 90301957
Duodenal ulcer perforation 219.17 9.86 5 99641 221283 90307518
Systemic lupus erythematosus 198.28 9.86 75 99571 361821 90166980
Haemoglobin decreased 183.54 9.86 489 99157 161467 90367334
Folliculitis 177.76 9.86 12 99634 204341 90324460
Muscle injury 160.89 9.86 8 99638 176646 90352155
Blood iron decreased 150.13 9.86 138 99508 17821 90510980
Colitis ulcerative 147.06 9.86 249 99397 60017 90468784
Irritable bowel syndrome 145.83 9.86 26 99620 207422 90321379
Wound 145.15 9.86 76 99570 302904 90225897
Liver injury 129.87 9.86 17 99629 170550 90358251
Product dose omission issue 125.51 9.86 643 99003 291044 90237757
Anaemia 118.79 9.86 728 98918 352074 90176727
Sleep disorder due to general medical condition, insomnia type 116.63 9.86 6 99640 128688 90400113
Ill-defined disorder 114.14 9.86 31 99615 184860 90343941
Blood cholesterol increased 114.02 9.86 43 99603 207969 90320832
Premature labour 112.23 9.86 103 99543 13273 90515528
Heavy menstrual bleeding 111.57 9.86 125 99521 20405 90508396
Discomfort 109.21 9.86 85 99561 274250 90254551
Haematochezia 107.94 9.86 240 99406 70673 90458128
Premature delivery 103.77 9.86 167 99479 38595 90490206
Blister 101.51 9.86 79 99567 254919 90273882
Choreoathetosis 101.15 9.86 34 99612 558 90528243
Swelling 99.30 9.86 194 99452 418864 90109937
Abdominal pain 97.29 9.86 756 98890 394965 90133836
Fibromyalgia 96.90 9.86 53 99593 206216 90322585
Contraindicated product administered 96.81 9.86 126 99520 320013 90208788
Stomatitis 95.07 9.86 97 99549 274601 90254200
Impaired healing 93.92 9.86 72 99574 234127 90294674
Type 2 diabetes mellitus 91.50 9.86 55 99591 203189 90325612
Facet joint syndrome 91.04 9.86 4 99642 98385 90430416
Mobility decreased 90.85 9.86 85 99561 250649 90278152
Drug intolerance 85.25 9.86 233 99413 447358 90081443
Synovitis 84.91 9.86 145 99501 329607 90199194
Lip dry 84.71 9.86 7 99639 100948 90427853
General physical health deterioration 84.45 9.86 164 99482 354951 90173850
Hypercholesterolaemia 81.95 9.86 8 99638 100884 90427917
Breast cancer stage III 79.59 9.86 3 99643 84444 90444357
Grip strength decreased 78.85 9.86 6 99640 92570 90436231
Blood parathyroid hormone decreased 78.00 9.86 81 99565 12135 90516666
Bursitis 77.70 9.86 24 99622 131630 90397171
Granuloma skin 77.69 9.86 76 99570 10604 90518197
Prescribed overdose 71.33 9.86 11 99635 97614 90431187
Peripheral venous disease 69.91 9.86 6 99640 83915 90444886
Weight decreased 69.42 9.86 680 98966 379230 90149571
Confusional state 68.42 9.86 208 99438 385997 90142804
Athetosis 66.38 9.86 16 99630 69 90528732
Psoriatic arthropathy 65.82 9.86 93 99553 228242 90300559
Defaecation urgency 64.27 9.86 54 99592 6188 90522613
Joint range of motion decreased 63.47 9.86 35 99611 135608 90393193
Illness 63.01 9.86 216 99430 81753 90447048
Panniculitis 61.98 9.86 78 99568 14380 90514421
Exposure during pregnancy 61.02 9.86 460 99186 237950 90290851
Heart rate increased 60.96 9.86 266 99380 112636 90416165
C-reactive protein abnormal 59.45 9.86 33 99613 127396 90401405
Maternal exposure during breast feeding 58.32 9.86 51 99595 6169 90522632
Therapeutic reaction time decreased 58.22 9.86 41 99605 3617 90525184
Breath sounds abnormal 58.15 9.86 78 99568 15308 90513493
Complication of device insertion 57.49 9.86 64 99582 10372 90518429
Nasal congestion 56.59 9.86 211 99435 83203 90445598
Wheezing 53.95 9.86 113 99533 237967 90290834
Hypersensitivity 53.87 9.86 287 99359 454390 90074411
Gastrointestinal haemorrhage 53.67 9.86 219 99427 90029 90438772
Abdominal discomfort 52.91 9.86 308 99338 477020 90051781
Obesity 52.68 9.86 25 99621 105482 90423319
Injury 52.41 9.86 85 99561 197264 90331537
Skin necrosis 52.35 9.86 78 99568 16863 90511938
Chronic disease 51.68 9.86 16 99630 199 90528602
Vaginal haemorrhage 51.18 9.86 109 99537 31162 90497639
Off label use 51.12 9.86 1578 98068 1100674 89428127
Full blood count abnormal 50.30 9.86 119 99527 36478 90492323
Hepatic enzyme increased 48.92 9.86 217 99429 360519 90168282
Hair follicle tumour benign 48.48 9.86 18 99628 400 90528401
Epilepsy 48.47 9.86 15 99631 82191 90446610
Inappropriate schedule of product administration 48.23 9.86 306 99340 149627 90379174
Wound infection 47.58 9.86 29 99617 106373 90422428
Mineral supplementation 47.54 9.86 21 99625 739 90528062
Treatment failure 46.75 9.86 174 99472 303754 90225047
Infusion related reaction 46.13 9.86 269 99377 416511 90112290
Lower respiratory tract infection 45.80 9.86 133 99513 250526 90278275
Clostridium difficile infection 45.70 9.86 114 99532 36131 90492670
Diarrhoea 45.48 9.86 1352 98294 937838 89590963
Poor venous access 45.41 9.86 79 99567 19448 90509353
Iron deficiency anaemia 45.27 9.86 88 99558 23574 90505227
Autoimmune disorder 45.26 9.86 14 99632 76730 90452071
Drug abuse 45.13 9.86 17 99629 82330 90446471
Haemorrhoids 44.77 9.86 94 99552 26608 90502193
Overdose 44.68 9.86 65 99581 157644 90371157
Arthropathy 44.58 9.86 229 99417 366013 90162788
Pancreatitis haemorrhagic 44.07 9.86 19 99627 630 90528171
Device expulsion 43.79 9.86 121 99525 40765 90488036
Transfusion 43.63 9.86 73 99573 17415 90511386
Rheumatoid nodule 43.57 9.86 79 99567 20087 90508714
Gastrointestinal tract mucosal pigmentation 42.46 9.86 19 99627 690 90528111
Alopecia 41.75 9.86 346 99300 494725 90034076
Blood albumin decreased 41.73 9.86 70 99576 16733 90512068
Caesarean section 41.70 9.86 74 99572 18503 90510298
Basal cell carcinoma 41.03 9.86 104 99542 33285 90495516
Uterine leiomyoma 40.94 9.86 55 99591 10809 90517992
Back pain 40.32 9.86 529 99117 316646 90212155
Blood pressure fluctuation 39.30 9.86 137 99509 52276 90476525
Myelosuppression 39.23 9.86 6 99640 53585 90475216
Bone erosion 38.67 9.86 6 99640 53015 90475786
Flushing 38.62 9.86 196 99450 88295 90440506
Joint swelling 37.93 9.86 362 99284 502938 90025863
Urinary tract infection 37.29 9.86 506 99140 305126 90223675
Iron deficiency 36.74 9.86 49 99597 9563 90519238
Device dislocation 36.56 9.86 96 99550 31386 90497415
Dermatitis atopic 36.33 9.86 80 99566 23392 90505409
Nail disorder 36.25 9.86 10 99636 59057 90469744
Crohn's disease 36.18 9.86 35 99611 4816 90523985
Fatigue 36.08 9.86 1581 98065 1152442 89376359
Skin neoplasm excision 36.04 9.86 23 99623 1723 90527078
Intestinal obstruction 35.99 9.86 106 99540 37025 90491776
Allergy to metals 35.54 9.86 19 99627 1021 90527780
Hypercalcaemia 35.36 9.86 100 99546 34140 90494661
Injection site pain 34.69 9.86 317 99329 173382 90355419
Faeces discoloured 34.52 9.86 74 99572 21246 90507555
Rash pruritic 34.41 9.86 180 99466 82034 90446767
Lower limb fracture 34.23 9.86 26 99620 84987 90443814
Serum ferritin decreased 34.14 9.86 26 99620 2588 90526213
Therapeutic product effect decreased 34.08 9.86 173 99473 277398 90251403
Incorrect dose administered 33.86 9.86 174 99472 78756 90450045
Intentional overdose 33.74 9.86 32 99614 93802 90434999
Toxicity to various agents 33.33 9.86 183 99463 287663 90241138
Anal fissure 33.12 9.86 35 99611 5350 90523451
Ulcer 32.95 9.86 95 99551 32787 90496014
Dry skin 32.94 9.86 187 99459 87886 90440915
Blepharospasm 32.90 9.86 10 99636 55435 90473366
Device placement issue 32.88 9.86 23 99623 2007 90526794
Neutropenia 32.49 9.86 132 99514 224772 90304029
Night sweats 31.85 9.86 58 99588 128708 90400093
Skin ulcer 31.76 9.86 124 99522 49951 90478850
Congenital cytomegalovirus infection 31.21 9.86 10 99636 140 90528661
Hip arthroplasty 31.07 9.86 23 99623 76185 90452616
Lung disorder 30.80 9.86 75 99571 149808 90378993
Back injury 30.33 9.86 7 99639 46615 90482186
Headache 30.32 9.86 1197 98449 861549 89667252
Drug-induced liver injury 29.97 9.86 33 99613 90285 90438516
Stress 29.90 9.86 172 99474 81223 90447578
Oropharyngeal pain 29.86 9.86 223 99423 114964 90413837
Frequent bowel movements 29.85 9.86 133 99513 56802 90471999
Appetite disorder 29.59 9.86 43 99603 9090 90519711
Delirium 29.56 9.86 43 99603 104316 90424485
Chills 29.54 9.86 247 99399 131734 90397067
Pyrexia 29.47 9.86 530 99116 659955 89868846
Complications of bone marrow transplant 29.42 9.86 13 99633 458 90528343
Arthritis infective 29.42 9.86 40 99606 7952 90520849
Blood pressure increased 29.39 9.86 339 99307 196878 90331923
Gastrointestinal disorder 29.27 9.86 164 99482 256523 90272278
Gait inability 28.76 9.86 75 99571 146381 90382420
Deafness congenital 28.63 9.86 9 99637 118 90528683
Pericoronitis 28.36 9.86 9 99637 122 90528679
Breast cancer stage II 28.17 9.86 3 99643 35331 90493470
Neoplasm skin 27.94 9.86 25 99621 3117 90525684
Liver disorder 27.93 9.86 57 99589 121212 90407589
Haemorrhage 27.75 9.86 150 99496 69219 90459582
Drug level decreased 27.52 9.86 43 99603 9687 90519114
Carbuncle 27.39 9.86 18 99628 1418 90527383
Drug interaction 27.17 9.86 185 99461 276268 90252533
Road traffic accident 27.05 9.86 48 99598 107578 90421223
Abnormal faeces 26.99 9.86 35 99611 6647 90522154
Drug eruption 26.93 9.86 93 99553 35314 90493487
Arthritis 26.93 9.86 292 99354 167023 90361778
Lupus-like syndrome 26.91 9.86 10 99636 48836 90479965
Skin disorder 26.70 9.86 95 99551 36611 90492190
Hypothalamo-pituitary disorder 26.37 9.86 21 99625 2231 90526570
Loss of personal independence in daily activities 25.97 9.86 246 99400 135859 90392942
Erythema 25.71 9.86 374 99272 228872 90299929
Red blood cell count decreased 25.61 9.86 110 99536 46241 90482560
Onychomycosis 25.57 9.86 5 99641 37371 90491430
Febrile neutropenia 25.42 9.86 89 99557 158260 90370541
Cough 25.05 9.86 556 99090 368406 90160395
Embedded device 25.05 9.86 27 99619 4221 90524580
Hepatosplenic T-cell lymphoma 24.80 9.86 13 99633 671 90528130
Dry mouth 24.75 9.86 111 99535 183948 90344853
Vitamin D decreased 24.71 9.86 46 99600 11933 90516868
Myringotomy 24.51 9.86 6 99640 28 90528773
Haematocrit decreased 24.46 9.86 101 99545 41731 90487070
Loss of therapeutic response 24.15 9.86 18 99628 1734 90527067
Rheumatoid factor positive 24.00 9.86 102 99544 171548 90357253
Medication error 23.86 9.86 35 99611 84617 90444184
Intermenstrual bleeding 23.68 9.86 39 99607 9184 90519617
Vascular device infection 23.54 9.86 45 99601 11907 90516894
Drug ineffective 23.38 9.86 1265 98381 1383033 89145768
Hypervolaemia 23.16 9.86 84 99562 32673 90496128
Fluid retention 23.09 9.86 171 99475 87920 90440881
Reflux gastritis 22.96 9.86 16 99630 1388 90527413
Feeling abnormal 22.95 9.86 283 99363 166952 90361849
Small intestinal obstruction 22.89 9.86 63 99583 21171 90507630
Premature baby 22.80 9.86 70 99576 25007 90503794
Blood potassium decreased 22.44 9.86 108 99538 47619 90481182
Malabsorption 22.30 9.86 28 99618 5150 90523651
Uterine perforation 22.23 9.86 34 99612 7520 90521281
Constipation 22.12 9.86 432 99214 279963 90248838
Polyp 21.93 9.86 34 99612 7610 90521191
Mucous stools 21.90 9.86 28 99618 5243 90523558
Small intestine ulcer 21.83 9.86 10 99636 384 90528417
Acne 21.79 9.86 75 99571 28432 90500369
Iodine allergy 21.66 9.86 13 99633 873 90527928
Intestinal resection 21.61 9.86 21 99625 2906 90525895
Urticaria 21.43 9.86 230 99416 312504 90216297
Premature separation of placenta 21.41 9.86 19 99627 2343 90526458
Hot flush 21.39 9.86 125 99521 59363 90469438
Dysmenorrhoea 21.30 9.86 26 99620 4646 90524155
Drug level below therapeutic 21.25 9.86 29 99617 5785 90523016
Monoclonal immunoglobulin present 21.10 9.86 18 99628 2106 90526695
Pre-eclampsia 21.03 9.86 41 99605 11007 90517794
Abdominal pain lower 21.01 9.86 77 99569 30100 90498701
Joint space narrowing 21.00 9.86 12 99634 735 90528066
Foreign body in reproductive tract 20.63 9.86 14 99632 1163 90527638
Foetal growth restriction 20.58 9.86 37 99609 9343 90519458
Flatulence 20.47 9.86 95 99551 41272 90487529
Serotonin syndrome 20.46 9.86 8 99638 37879 90490922
Skin warm 20.41 9.86 33 99613 7654 90521147
Hyponatraemia 20.15 9.86 77 99569 133461 90395340
Body height decreased 19.95 9.86 42 99604 11907 90516894
Sciatica 19.84 9.86 52 99594 101330 90427471
Sleep disorder 19.71 9.86 132 99514 197898 90330903
Rhinorrhoea 19.60 9.86 165 99481 88151 90440650
Faecal calprotectin increased 19.51 9.86 23 99623 3964 90524837
Delivery 19.47 9.86 16 99630 1777 90527024
Product quality issue 19.38 9.86 36 99610 79289 90449512
Asthenia 19.26 9.86 743 98903 533008 89995793
Chorea 19.18 9.86 17 99629 2093 90526708
Blood growth hormone increased 19.01 9.86 10 99636 520 90528281
Infection 18.94 9.86 282 99364 361812 90166989
Splenomegaly 18.83 9.86 43 99603 12881 90515920
Injection site erythema 18.77 9.86 178 99468 98324 90430477
Small intestinal stenosis 18.68 9.86 11 99635 713 90528088
Suicide attempt 18.61 9.86 34 99612 75365 90453436
Preterm premature rupture of membranes 18.57 9.86 15 99631 1626 90527175
Dizziness 18.45 9.86 808 98838 588476 89940325
Pulmonary arterial hypertension 18.39 9.86 67 99579 26120 90502681
Sinus pain 18.38 9.86 26 99620 5363 90523438
Limb injury 18.36 9.86 76 99570 31432 90497369
Red blood cells urine positive 18.15 9.86 20 99626 3205 90525596
Deafness 17.88 9.86 60 99586 22454 90506347
Overweight 17.87 9.86 27 99619 5907 90522894
Platelet count increased 17.83 9.86 57 99589 20802 90507999
Liver function test increased 17.79 9.86 42 99604 84813 90443988
Acute lung injury 17.61 9.86 14 99632 1484 90527317
COVID-19 17.58 9.86 272 99374 168571 90360230
Device breakage 17.52 9.86 44 99602 14000 90514801
Planning to become pregnant 17.44 9.86 3 99643 0 90528801
Nephrogenic systemic fibrosis 17.35 9.86 22 99624 4086 90524715
Incorrect route of product administration 17.35 9.86 18 99628 50608 90478193
Bowel movement irregularity 17.34 9.86 28 99618 6486 90522315
Skin discolouration 17.17 9.86 95 99551 44220 90484581
Maternal exposure before pregnancy 17.11 9.86 38 99608 11175 90517626
Depressed level of consciousness 16.93 9.86 34 99612 72750 90456051
Natural killer cell count 16.84 9.86 4 99642 16 90528785
Amegakaryocytic thrombocytopenia 16.84 9.86 4 99642 16 90528785
Complication of device removal 16.81 9.86 27 99619 6228 90522573
Gastrointestinal inflammation 16.77 9.86 28 99618 6668 90522133
Leukopenia 16.57 9.86 56 99590 100654 90428147
Dyschezia 16.52 9.86 18 99628 2847 90525954
Intercepted medication error 16.52 9.86 11 99635 886 90527915
Eosinophilic pneumonia chronic 16.47 9.86 7 99639 224 90528577
Heart rate decreased 16.45 9.86 108 99538 53397 90475404
Bone density decreased 16.32 9.86 49 99597 17296 90511505
Kidney infection 16.29 9.86 64 99582 25852 90502949
Coeliac disease 16.28 9.86 15 99631 44595 90484206
Fistula 16.28 9.86 39 99607 12050 90516751
Viral infection 16.19 9.86 89 99557 41325 90487476
Cardiac arrest 16.16 9.86 60 99586 104875 90423926
Musculoskeletal pain 16.13 9.86 116 99530 171135 90357666
Vascular stenosis 16.12 9.86 9 99637 527 90528274
Diarrhoea haemorrhagic 16.12 9.86 36 99610 10627 90518174
Amnesia 16.09 9.86 63 99583 108442 90420359
Empty sella syndrome 16.09 9.86 5 99641 63 90528738
Retching 16.06 9.86 52 99594 19107 90509694
Full blood count decreased 16.05 9.86 70 99576 29619 90499182
Knee arthroplasty 16.02 9.86 43 99603 83139 90445662
Coma 16.00 9.86 35 99611 72597 90456204
Hospitalisation 15.97 9.86 213 99433 127887 90400914
Antineutrophil cytoplasmic antibody positive 15.74 9.86 10 99636 743 90528058
Macrophages increased 15.64 9.86 4 99642 23 90528778
Acute kidney injury 15.57 9.86 253 99393 320134 90208667
Crystal urine present 15.57 9.86 13 99633 1477 90527324
Sinus disorder 15.52 9.86 77 99569 34370 90494431
Abdominal abscess 15.51 9.86 24 99622 5363 90523438
Postpartum haemorrhage 15.47 9.86 16 99630 2385 90526416
Eosinophilia 15.45 9.86 6 99640 28527 90500274
Muscular weakness 15.38 9.86 149 99497 206517 90322284
Vision blurred 15.28 9.86 187 99459 110106 90418695
Eczema 15.23 9.86 105 99541 52765 90476036
Anaemia of pregnancy 15.10 9.86 6 99640 161 90528640
Pelvic pain 15.03 9.86 44 99602 15313 90513488
Dyspnoea exertional 14.97 9.86 133 99513 72155 90456646
Hypophosphataemia 14.96 9.86 43 99603 14811 90513990
Movement disorder 14.62 9.86 67 99579 28952 90499849
Anal incontinence 14.47 9.86 45 99601 16185 90512616
Dehydration 14.46 9.86 297 99349 194150 90334651
Skin lesion 14.41 9.86 80 99566 37285 90491516
Body temperature fluctuation 14.37 9.86 15 99631 2260 90526541
Vein rupture 14.34 9.86 13 99633 1648 90527153
Laryngitis 14.29 9.86 21 99625 50732 90478069
Stress at work 14.27 9.86 12 99634 1377 90527424
Early satiety 14.13 9.86 12 99634 1395 90527406
Palindromic rheumatism 14.12 9.86 6 99640 192 90528609
Drug hypersensitivity 14.08 9.86 395 99251 463214 90065587
Polymenorrhoea 14.06 9.86 12 99634 1405 90527396
Joint dislocation 14.02 9.86 17 99629 44565 90484236
Wound infection bacterial 14.00 9.86 9 99637 683 90528118
Exostosis 13.99 9.86 23 99623 53111 90475690
Muscle spasticity 13.96 9.86 11 99635 35311 90493490
Epistaxis 13.89 9.86 149 99497 84976 90443825
Rectal tenesmus 13.88 9.86 11 99635 1161 90527640
Rash macular 13.86 9.86 68 99578 30212 90498589
Oedema 13.83 9.86 147 99499 200148 90328653
Product label confusion 13.78 9.86 4 99642 22846 90505955
Drug reaction with eosinophilia and systemic symptoms 13.77 9.86 16 99630 42742 90486059
Cytomegalovirus infection 13.75 9.86 6 99640 26596 90502205
Uterine atony 13.73 9.86 7 99639 341 90528460
Bone marrow reticulin fibrosis 13.70 9.86 6 99640 207 90528594
Bronchospasm 13.69 9.86 3 99643 20706 90508095
Acute myeloid leukaemia 13.63 9.86 3 99643 20637 90508164
Blood pressure decreased 13.61 9.86 134 99512 74761 90454040
Premature rupture of membranes 13.60 9.86 23 99623 5535 90523266
Toxoplasmosis 13.54 9.86 13 99633 1772 90527029
Dysstasia 13.49 9.86 59 99587 24993 90503808
Injection site alopecia 13.45 9.86 4 99642 43 90528758
Hyperparathyroidism secondary 13.44 9.86 13 99633 1788 90527013
Maternal exposure timing unspecified 13.44 9.86 4 99642 22479 90506322
Autoimmune lung disease 13.43 9.86 5 99641 112 90528689
Multiple organ dysfunction syndrome 13.41 9.86 35 99611 68301 90460500
Chronic spontaneous urticaria 13.33 9.86 13 99633 1807 90526994
Twin pregnancy 13.31 9.86 11 99635 1232 90527569
Rash 13.27 9.86 728 98918 795372 89733429
Nausea 13.14 9.86 1403 98243 1108913 89419888
Skin exfoliation 13.07 9.86 123 99523 67790 90461011
Septic shock 13.04 9.86 48 99598 84112 90444689
Blood pressure systolic abnormal 12.98 9.86 49 99597 19429 90509372
Foot deformity 12.93 9.86 29 99617 59622 90469179
Intentional dose omission 12.91 9.86 46 99600 17737 90511064
Walking aid user 12.89 9.86 12 99634 35494 90493307
Surgery 12.84 9.86 89 99557 44798 90484003
Thrombosis 12.79 9.86 130 99516 73121 90455680
Tendon injury 12.73 9.86 14 99632 2239 90526562
Infusion site haemorrhage 12.72 9.86 22 99624 5389 90523412
Contusion 12.66 9.86 197 99449 251019 90277782
Upper-airway cough syndrome 12.61 9.86 41 99605 15094 90513707
Arthropod bite 12.58 9.86 29 99617 8738 90520063
Chest discomfort 12.58 9.86 218 99428 138147 90390654
Normal newborn 12.57 9.86 55 99591 23307 90505494
Ileostomy 12.55 9.86 13 99633 1941 90526860
Emotional distress 12.51 9.86 76 99570 36586 90492215
Agranulocytosis 12.50 9.86 12 99634 34990 90493811
Delayed haemolytic transfusion reaction 12.43 9.86 3 99643 13 90528788
Pleural calcification 12.42 9.86 4 99642 57 90528744
Drug specific antibody present 12.42 9.86 22 99624 5492 90523309
Blood pressure diastolic abnormal 12.42 9.86 49 99597 19832 90508969
Uterine contractions during pregnancy 12.28 9.86 8 99638 621 90528180
Hernia 12.27 9.86 39 99607 14192 90514609
Livedo reticularis 12.26 9.86 17 99629 3442 90525359
Amniotic cavity infection 12.20 9.86 11 99635 1385 90527416
Low birth weight baby 12.17 9.86 30 99616 9437 90519364
Cyst 12.16 9.86 43 99603 16518 90512283
Impaired quality of life 12.08 9.86 54 99592 23090 90505711
Cytokine release syndrome 11.99 9.86 8 99638 27965 90500836
Infusion site bruising 11.92 9.86 19 99627 4353 90524448
Transferrin saturation increased 11.88 9.86 4 99642 66 90528735
Cognitive disorder 11.83 9.86 38 99608 69369 90459432
Injection site papule 11.75 9.86 9 99637 903 90527898
Mean cell haemoglobin concentration decreased 11.74 9.86 19 99627 4409 90524392
Dermatitis 11.72 9.86 52 99594 22168 90506633
Productive cough 11.71 9.86 133 99513 76930 90451871
Therapeutic response shortened 11.66 9.86 53 99593 22826 90505975
Pollakiuria 11.63 9.86 69 99577 32936 90495865
Posterior reversible encephalopathy syndrome 11.61 9.86 5 99641 22334 90506467
Wrist deformity 11.61 9.86 16 99630 3222 90525579
Hip fracture 11.56 9.86 69 99577 33008 90495793
Vomiting projectile 11.56 9.86 12 99634 1797 90527004
Pancytopenia 11.55 9.86 81 99565 120182 90408619
Therapeutic response decreased 11.52 9.86 150 99496 89579 90439222
Polyhydramnios 11.50 9.86 14 99632 2494 90526307
Bronchitis 11.50 9.86 234 99412 152693 90376108
Purulent discharge 11.45 9.86 21 99625 5384 90523417
Blood pressure systolic increased 11.39 9.86 106 99540 58239 90470562
Pain in jaw 11.37 9.86 91 99555 47894 90480907
Shock 11.33 9.86 9 99637 28769 90500032
Thyroid adenoma 11.32 9.86 5 99641 176 90528625
Hepatic function abnormal 11.31 9.86 21 99625 46267 90482534
Bone pain 11.31 9.86 111 99535 61872 90466929
Cervical polyp 11.30 9.86 6 99640 318 90528483
Arthralgia 11.28 9.86 998 98648 777524 89751277
Fungal infection 11.28 9.86 83 99563 42578 90486223
Uterine infection 11.27 9.86 7 99639 500 90528301
Malignant neoplasm progression 11.26 9.86 70 99576 106800 90422001
Cholestasis 11.25 9.86 14 99632 36285 90492516
Hepatic hypertrophy 11.23 9.86 3 99643 21 90528780
Vaginal infection 11.12 9.86 27 99619 8413 90520388
Myelofibrosis 11.12 9.86 11 99635 1556 90527245
Post procedural hypotension 11.11 9.86 3 99643 22 90528779
Pharyngitis streptococcal 11.06 9.86 35 99611 12707 90516094
Mastitis 11.05 9.86 15 99631 2978 90525823
Fall 11.00 9.86 641 99005 481169 90047632
Blood glucose decreased 11.00 9.86 53 99593 23376 90505425
Impaired fasting glucose 11.00 9.86 6 99640 336 90528465
Myalgia 10.96 9.86 261 99385 174864 90353937
Glomerulonephritis rapidly progressive 10.95 9.86 10 99636 1280 90527521
Cardiac disorder 10.94 9.86 103 99543 56769 90472032
Molluscum contagiosum 10.93 9.86 6 99640 340 90528461
Sterile pyuria 10.88 9.86 3 99643 24 90528777
Peritonitis bacterial 10.84 9.86 20 99626 5151 90523650
Product dose omission in error 10.82 9.86 48 99598 20455 90508346
Head discomfort 10.81 9.86 41 99605 16292 90512509
Refractory cytopenia with unilineage dysplasia 10.78 9.86 7 99639 540 90528261
Xeroderma 10.77 9.86 6 99640 350 90528451
Uterine haemorrhage 10.76 9.86 19 99627 4733 90524068
Menstrual disorder 10.75 9.86 22 99624 6116 90522685
Renal cyst 10.72 9.86 35 99611 12915 90515886
Injection site bruising 10.71 9.86 96 99550 52211 90476590
Respiratory disorder 10.69 9.86 36 99610 64780 90464021
Cardiac failure congestive 10.65 9.86 160 99486 98534 90430267
Wrong dose 10.64 9.86 12 99634 1972 90526829
Obstruction 10.64 9.86 17 99629 3904 90524897
Pulmonary cavitation 10.63 9.86 9 99637 1042 90527759
Foetal exposure during pregnancy 10.46 9.86 82 99564 42893 90485908
Skin fissures 10.45 9.86 48 99598 20761 90508040
Nitrite urine present 10.42 9.86 9 99637 1070 90527731
Gastrointestinal stromal tumour 10.42 9.86 10 99636 1363 90527438
Morganella infection 10.40 9.86 8 99638 808 90527993
Disability 10.39 9.86 18 99628 40727 90488074
Autonomic dysreflexia 10.32 9.86 6 99640 380 90528421
Hepatocellular injury 10.26 9.86 10 99636 28948 90499853
Urine albumin/creatinine ratio decreased 10.26 9.86 4 99642 102 90528699
Exposure to fungus 10.26 9.86 5 99641 221 90528580
Immunodeficiency 10.23 9.86 20 99626 43214 90485587
Coombs negative haemolytic anaemia 10.22 9.86 6 99640 387 90528414
Creatinine renal clearance decreased 10.19 9.86 4 99642 18895 90509906
Antineutrophil cytoplasmic antibody increased 10.07 9.86 5 99641 230 90528571
Heart rate irregular 10.06 9.86 53 99593 24215 90504586
Fibrosis 10.03 9.86 21 99625 5931 90522870
Fishbane reaction 10.02 9.86 3 99643 33 90528768
Human chorionic gonadotropin negative 10.02 9.86 3 99643 33 90528768
Anion gap 9.98 9.86 9 99637 1133 90527668
Hypokalaemia 9.98 9.86 94 99552 131022 90397779
Localised infection 9.87 9.86 67 99579 33495 90495306

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Colitis ulcerative 253.17 11.39 200 37850 25975 42557310
Blood iron decreased 119.62 11.39 73 37977 6245 42577040
Nipple swelling 90.36 11.39 27 38023 370 42582915
Fatigue 87.17 11.39 675 37375 434966 42148319
Haematochezia 86.76 11.39 173 37877 58263 42525022
Diarrhoea 79.24 11.39 690 37360 460159 42123126
Nipple pain 67.12 11.39 28 38022 1059 42582226
Frequent bowel movements 65.56 11.39 88 37962 21319 42561966
Drug abuse 63.56 11.39 9 38041 104762 42478523
Abdominal pain 57.20 11.39 327 37723 190144 42393141
Haemoglobin decreased 51.19 11.39 244 37806 132227 42451058
Polyp 46.18 11.39 36 38014 4578 42578707
Weight decreased 44.03 11.39 327 37723 207621 42375664
Polyneuropathy in malignant disease 42.33 11.39 15 38035 361 42582924
Faeces discoloured 41.84 11.39 63 37987 16951 42566334
Inappropriate schedule of product administration 40.99 11.39 182 37868 95720 42487565
Acute kidney injury 40.25 11.39 180 37870 367157 42216128
Large intestine polyp 39.51 11.39 45 38005 9220 42574065
Device interaction 39.25 11.39 16 38034 570 42582715
Toxicity to various agents 39.21 11.39 92 37958 229044 42354241
Constipation 38.87 11.39 263 37787 162028 42421257
Asthenia 37.42 11.39 399 37651 280394 42302891
Interstitial lung disease 36.92 11.39 12 38038 78450 42504835
Febrile neutropenia 36.42 11.39 69 37981 185634 42397651
Gastrointestinal tract mucosal pigmentation 36.04 11.39 15 38035 564 42582721
Off label use 35.61 11.39 781 37269 637554 41945731
Full blood count decreased 34.32 11.39 64 37986 20496 42562789
Faeces soft 34.02 11.39 31 38019 4881 42578404
Exposure during pregnancy 33.91 11.39 40 38010 8508 42574777
Nephrogenic systemic fibrosis 32.21 11.39 26 38024 3475 42579810
Weight increased 31.44 11.39 184 37866 107799 42475486
Crohn's disease 31.43 11.39 24 38026 2960 42580325
Clostridium difficile infection 31.13 11.39 65 37985 22594 42560691
Drug interaction 30.94 11.39 128 37922 266871 42316414
Thrombocytopenia 30.50 11.39 79 37971 190200 42393085
Mucous stools 30.26 11.39 22 38028 2518 42580767
Gastrointestinal inflammation 29.91 11.39 28 38022 4564 42578721
Flatulence 29.83 11.39 68 37982 25084 42558201
Gastrointestinal haemorrhage 28.76 11.39 167 37883 97559 42485726
Anal stenosis 28.64 11.39 11 38039 334 42582951
Iron deficiency anaemia 27.50 11.39 45 38005 12994 42570291
Mineral supplementation 27.09 11.39 8 38042 105 42583180
Intestinal resection 26.53 11.39 18 38032 1846 42581439
Faecal calprotectin increased 26.42 11.39 22 38028 3072 42580213
Anaemia 26.34 11.39 373 37677 279905 42303380
Product dose omission issue 26.25 11.39 231 37819 154134 42429151
Blood pressure fluctuation 25.77 11.39 67 37983 26841 42556444
Blood pressure increased 25.47 11.39 167 37883 101761 42481524
Defaecation urgency 24.97 11.39 23 38027 3671 42579614
Maternal exposure before pregnancy 24.46 11.39 14 38036 1063 42582222
Abdominal discomfort 24.39 11.39 132 37918 75123 42508162
Allodynia 24.26 11.39 14 38036 1080 42582205
Neutropenia 24.10 11.39 94 37956 199337 42383948
Suicide attempt 23.62 11.39 6 38044 46094 42537191
Rhabdomyolysis 23.50 11.39 21 38029 77998 42505287
Faeces hard 23.17 11.39 16 38034 1688 42581597
Haemorrhage 22.95 11.39 111 37939 60452 42522833
Drug level decreased 21.81 11.39 35 38015 9942 42573343
Premature baby 21.51 11.39 57 37993 23096 42560189
Myelosuppression 21.25 11.39 5 38045 40456 42542829
Autoscopy 20.43 11.39 8 38042 256 42583029
Thrombosis 18.81 11.39 115 37935 68396 42514889
Agitation 18.56 11.39 18 38032 64296 42518989
Arthralgia 18.40 11.39 271 37779 204967 42378318
Heart rate increased 18.34 11.39 95 37955 53160 42530125
Aplasia pure red cell 18.28 11.39 27 38023 7139 42576146
Gastroenteritis viral 18.25 11.39 29 38021 8170 42575115
Therapeutic reaction time decreased 18.21 11.39 15 38035 2063 42581222
Abdominal distension 18.20 11.39 118 37932 71617 42511668
Intestinal stenosis 18.07 11.39 17 38033 2787 42580498
Cataract 17.82 11.39 64 37986 30540 42552745
Intentional product use issue 17.52 11.39 117 37933 71716 42511569
Hyperaesthesia 17.51 11.39 24 38026 5928 42577357
Enterobacter pneumonia 17.50 11.39 9 38041 552 42582733
Nasopharyngitis 17.11 11.39 131 37919 83865 42499420
Poor venous access 16.63 11.39 26 38024 7226 42576059
Agitated depression 16.63 11.39 7 38043 271 42583014
Parkinsonism 16.41 11.39 32 38018 10591 42572694
Malaise 16.30 11.39 273 37777 211883 42371402
Drug-induced liver injury 16.08 11.39 7 38043 38266 42545019
Skin discolouration 16.04 11.39 48 38002 20842 42562443
Hypophosphataemia 15.96 11.39 48 38002 20897 42562388
Overdose 15.87 11.39 45 38005 105219 42478066
Blood loss anaemia 15.86 11.39 30 38020 9706 42573579
Neutrophil count decreased 15.82 11.39 20 38030 63395 42519890
Condition aggravated 15.69 11.39 323 37727 260431 42322854
Gastroduodenal haemorrhage 15.63 11.39 6 38044 182 42583103
Heart rate decreased 15.34 11.39 69 37981 36463 42546822
Anal fissure 15.22 11.39 21 38029 5218 42578067
Back injury 15.06 11.39 19 38031 4329 42578956
Fluid retention 15.03 11.39 62 37988 31557 42551728
Skin induration 15.01 11.39 13 38037 1914 42581371
Fistula 14.95 11.39 26 38024 7886 42575399
Diet noncompliance 14.79 11.39 6 38044 211 42583074
Cytokine release syndrome 14.63 11.39 11 38039 44516 42538769
Leukopenia 14.43 11.39 28 38022 74718 42508567
Hernia 14.32 11.39 31 38019 11042 42572243
Coma 14.31 11.39 16 38034 53538 42529747
Muscle spasms 14.21 11.39 128 37922 85916 42497369
Intentional overdose 14.16 11.39 15 38035 51441 42531844
Vision blurred 14.03 11.39 89 37961 53610 42529675
Anal ulcer 13.63 11.39 10 38040 1161 42582124
Acute respiratory distress syndrome 13.48 11.39 5 38045 30103 42553182
Lactose intolerance 13.47 11.39 11 38039 1495 42581790
Bronchiolitis 13.42 11.39 17 38033 3889 42579396
Hip fracture 13.37 11.39 34 38016 13438 42569847
Quality of life decreased 13.35 11.39 20 38030 5356 42577929
Aphthous ulcer 13.31 11.39 21 38029 5880 42577405
Abnormal faeces 13.30 11.39 17 38033 3924 42579361
Contusion 13.16 11.39 73 37977 41912 42541373
Hepatitis 13.15 11.39 4 38046 27296 42555989
Spondylitis 13.08 11.39 11 38039 1557 42581728
Drug level below therapeutic 13.01 11.39 22 38028 6523 42576762
Mucosal inflammation 12.92 11.39 15 38035 49359 42533926
Death 12.82 11.39 528 37522 470657 42112628
Hepatic cytolysis 12.81 11.39 4 38046 26840 42556445
Faecal calprotectin abnormal 12.40 11.39 6 38044 323 42582962
Aspartate aminotransferase increased 12.37 11.39 32 38018 77131 42506154
Eosinophilia 12.34 11.39 7 38043 32892 42550393
Cholestasis 12.33 11.39 7 38043 32872 42550413
Neurotoxicity 12.27 11.39 3 38047 23648 42559637
Meconium abnormal 12.22 11.39 4 38046 75 42583210
Angioedema 12.12 11.39 12 38038 42465 42540820
Electrocardiogram QT prolonged 12.09 11.39 15 38035 47930 42535355
Completed suicide 11.93 11.39 45 38005 96420 42486865
Low birth weight baby 11.89 11.39 27 38023 9928 42573357
Small intestinal ulcer haemorrhage 11.80 11.39 4 38046 84 42583201
Proctalgia 11.73 11.39 22 38028 7071 42576214
Hepatotoxicity 11.57 11.39 4 38046 25163 42558122
Prostate cancer metastatic 11.52 11.39 21 38029 6608 42576677
Pancreatitis acute 11.41 11.39 8 38042 33556 42549729
Vanishing bile duct syndrome 11.41 11.39 11 38039 1860 42581425
Rash maculo-papular 11.40 11.39 10 38040 37493 42545792

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Colitis ulcerative 301.79 10.31 381 111089 76982 110400847
Blood iron decreased 212.25 10.31 167 111303 19047 110458782
Hand deformity 185.93 10.31 8 111462 218498 110259331
Pericarditis 171.23 10.31 13 111457 219101 110258728
Haemoglobin decreased 167.03 10.31 591 110879 248136 110229693
Haematochezia 159.66 10.31 357 111113 115167 110362662
Glossodynia 153.27 10.31 21 111449 221983 110255846
Duodenal ulcer perforation 152.87 10.31 6 111464 177694 110300135
Abdominal pain 148.86 10.31 955 110515 512034 109965795
Helicobacter infection 144.37 10.31 10 111460 181867 110295962
Folliculitis 125.36 10.31 12 111458 167641 110310188
Muscle injury 120.28 10.31 5 111465 140802 110337027
Drug abuse 115.12 10.31 20 111450 177391 110300438
Premature delivery 114.89 10.31 148 111322 30484 110447345
Off label use 111.53 10.31 2124 109346 1498061 108979768
Product dose omission issue 109.72 10.31 625 110845 321157 110156672
Inappropriate schedule of product administration 108.77 10.31 450 111020 203187 110274642
Fatigue 106.38 10.31 1767 109703 1214191 109263638
Systemic lupus erythematosus 105.11 10.31 63 111407 254275 110223554
Heavy menstrual bleeding 104.03 10.31 104 111366 16261 110461568
Irritable bowel syndrome 95.27 10.31 24 111446 164191 110313638
Weight decreased 91.06 10.31 793 110677 467264 110010565
Defaecation urgency 90.14 10.31 73 111397 8674 110469155
Nipple swelling 87.12 10.31 27 111443 370 110477459
Liver injury 81.62 10.31 25 111445 150388 110327441
Choreoathetosis 81.53 10.31 38 111432 1660 110476169
Anaemia 81.36 10.31 876 110594 546210 109931619
Facet joint syndrome 80.86 10.31 4 111466 96824 110381005
Sleep disorder due to general medical condition, insomnia type 80.47 10.31 7 111463 105636 110372193
Granuloma skin 79.75 10.31 76 111394 11207 110466622
Blood parathyroid hormone decreased 79.21 10.31 81 111389 13008 110464821
Gastrointestinal tract mucosal pigmentation 78.61 10.31 34 111436 1243 110476586
Wound 76.50 10.31 74 111396 234363 110243466
Clostridium difficile infection 75.27 10.31 164 111306 51965 110425864
Therapeutic reaction time decreased 74.16 10.31 53 111417 5226 110472603
Neutropenia 73.74 10.31 168 111302 374452 110103377
Frequent bowel movements 71.42 10.31 195 111275 71195 110406634
Fibromyalgia 69.67 10.31 43 111427 170866 110306963
Complication of device insertion 69.16 10.31 63 111407 8775 110469054
Diarrhoea 68.83 10.31 1566 109904 1137939 109339890
Poor venous access 68.75 10.31 103 111367 24419 110453410
Faeces discoloured 68.62 10.31 123 111347 33825 110444004
Lip dry 67.80 10.31 10 111460 100073 110377756
Stomatitis 67.43 10.31 105 111365 270137 110207692
Breast cancer stage III 66.93 10.31 3 111467 79114 110398715
Gastrointestinal haemorrhage 66.90 10.31 337 111133 165181 110312648
Acute kidney injury 66.69 10.31 372 111098 635058 109842771
Mineral supplementation 66.56 10.31 27 111443 838 110476991
Athetosis 65.13 10.31 18 111452 160 110477669
Bursitis 64.60 10.31 25 111445 129893 110347936
Ill-defined disorder 64.58 10.31 39 111431 156814 110321015
Heart rate increased 63.98 10.31 301 111169 143533 110334296
Blood pressure fluctuation 63.83 10.31 193 111277 74631 110403198
Impaired healing 63.13 10.31 63 111407 196654 110281175
Exposure during pregnancy 62.90 10.31 334 111136 167090 110310739
Toxicity to various agents 62.84 10.31 260 111210 480295 109997534
Myelosuppression 62.60 10.31 10 111460 94330 110383499
Nipple pain 62.19 10.31 28 111442 1128 110476701
Anal fissure 61.34 10.31 62 111408 9819 110468010
Obesity 61.21 10.31 19 111451 113332 110364497
Panniculitis 61.13 10.31 77 111393 15505 110462324
Nasal congestion 60.36 10.31 227 111243 98055 110379774
Peripheral venous disease 60.35 10.31 7 111463 84110 110393719
Drug interaction 59.72 10.31 280 111190 499903 109977926
Premature labour 59.61 10.31 59 111411 9113 110468716
Iron deficiency anaemia 59.56 10.31 111 111359 31448 110446381
Hypercholesterolaemia 59.45 10.31 10 111460 90827 110387002
Febrile neutropenia 58.40 10.31 147 111323 316620 110161209
Blood cholesterol increased 58.36 10.31 60 111410 184725 110293104
Polyp 57.22 10.31 60 111410 9920 110467909
Grip strength decreased 56.71 10.31 7 111463 80167 110397662
Chronic disease 56.18 10.31 17 111453 214 110477615
Blister 55.15 10.31 90 111380 227286 110250543
Mobility decreased 54.81 10.31 97 111373 237325 110240504
Type 2 diabetes mellitus 54.34 10.31 59 111411 177173 110300656
Mucous stools 53.95 10.31 49 111421 6798 110471031
Device expulsion 53.80 10.31 105 111365 30786 110447043
Maternal exposure during breast feeding 53.75 10.31 40 111430 4198 110473631
Epilepsy 53.75 10.31 17 111453 100192 110377637
Faecal calprotectin increased 52.78 10.31 48 111422 6671 110471158
C-reactive protein abnormal 52.34 10.31 33 111437 129662 110348167
Synovitis 52.24 10.31 125 111345 273967 110203862
Condition aggravated 51.03 10.31 1031 110439 733805 109744024
Illness 50.63 10.31 190 111280 81981 110395848
Confusional state 50.44 10.31 272 111198 468408 110009421
Drug level decreased 49.30 10.31 76 111394 18472 110459357
Contraindicated product administered 49.10 10.31 111 111359 248156 110229673
Hair follicle tumour benign 48.48 10.31 18 111452 438 110477391
Overdose 48.32 10.31 102 111368 233692 110244137
Blood pressure increased 48.21 10.31 434 111036 257939 110219890
Urinary tract infection 48.20 10.31 522 110948 325760 110152069
Caesarean section 47.54 10.31 64 111406 13753 110464076
Rheumatoid nodule 46.86 10.31 78 111392 20218 110457611
Discomfort 45.79 10.31 92 111378 214615 110263214
Breath sounds abnormal 45.03 10.31 87 111383 25317 110452512
Flatulence 44.93 10.31 135 111335 52014 110425815
Skin necrosis 43.55 10.31 78 111392 21434 110456395
Autoimmune disorder 43.31 10.31 7 111463 65476 110412353
Large intestine polyp 43.10 10.31 64 111406 15053 110462776
Psoriatic arthropathy 42.22 10.31 84 111386 196677 110281152
Intestinal resection 40.93 10.31 33 111437 3896 110473933
Flushing 40.73 10.31 211 111259 104525 110373304
Arthralgia 40.44 10.31 1050 110420 778582 109699247
Drug level below therapeutic 40.06 10.31 54 111416 11619 110466210
Wound infection 39.68 10.31 24 111446 96441 110381388
Drug-induced liver injury 39.04 10.31 38 111432 120029 110357800
Drug intolerance 38.87 10.31 245 111225 406267 110071562
Basal cell carcinoma 38.82 10.31 117 111353 45153 110432676
Vaginal haemorrhage 38.63 10.31 81 111389 24993 110452836
Hepatic cytolysis 38.47 10.31 5 111465 55048 110422781
Hepatic function abnormal 38.47 10.31 21 111449 89274 110388555
Suicide attempt 38.15 10.31 29 111441 103365 110374464
Constipation 37.57 10.31 537 110933 357249 110120580
Ulcer 37.51 10.31 112 111358 43004 110434825
Device dislocation 37.26 10.31 92 111378 31612 110446217
Swelling 37.04 10.31 205 111265 350836 110126993
Nephrogenic systemic fibrosis 36.99 10.31 36 111434 5447 110472382
Wheezing 36.59 10.31 133 111337 255097 110222732
Intentional overdose 36.47 10.31 48 111422 132453 110345376
Polyneuropathy in malignant disease 36.38 10.31 15 111455 486 110477343
Uterine leiomyoma 36.24 10.31 42 111428 7758 110470071
Fluid retention 35.30 10.31 188 111282 94119 110383710
Abnormal faeces 35.22 10.31 45 111425 9191 110468638
Leukopenia 35.04 10.31 60 111410 148731 110329098
Pancreatitis haemorrhagic 34.62 10.31 18 111452 998 110476831
Pyrexia 34.53 10.31 668 110802 897597 109580232
Device placement issue 34.52 10.31 22 111448 1795 110476034
Sleep disorder 34.45 10.31 95 111375 198549 110279280
Incorrect dose administered 34.40 10.31 200 111270 103441 110374388
Joint range of motion decreased 33.67 10.31 44 111426 121788 110356041
Intestinal obstruction 33.56 10.31 124 111346 53103 110424726
Haemorrhage 33.55 10.31 203 111267 106489 110371340
Haemorrhoids 33.27 10.31 95 111375 35577 110442252
Adjustment disorder with depressed mood 33.17 10.31 3 111467 43880 110433949
Nail disorder 32.58 10.31 9 111461 57926 110419903
Iron deficiency 32.41 10.31 63 111407 18413 110459416
Transfusion 32.16 10.31 76 111394 25396 110452433
Injury 31.32 10.31 84 111386 177181 110300648
Gastrointestinal inflammation 31.28 10.31 43 111427 9426 110468403
Interstitial lung disease 31.18 10.31 58 111412 139276 110338553
Bone erosion 30.57 10.31 5 111465 46366 110431463
Headache 30.45 10.31 1131 110339 881246 109596583
General physical health deterioration 30.38 10.31 278 111192 425017 110052812
Back pain 30.32 10.31 534 110936 370462 110107367
Coma 30.14 10.31 45 111425 117824 110360005
Blepharospasm 29.96 10.31 9 111461 54842 110422987
Oropharyngeal pain 29.86 10.31 236 111234 135040 110342789
Lung disorder 29.83 10.31 88 111382 179959 110297870
Skin neoplasm excision 29.69 10.31 21 111449 2037 110475792
Heart rate decreased 29.64 10.31 163 111307 82593 110395236
Thrombocytopenia 29.50 10.31 218 111252 348667 110129162
Prescribed overdose 29.31 10.31 27 111443 87554 110390275
Asthenia 29.30 10.31 905 110565 688094 109789735
Neurotoxicity 29.09 10.31 4 111466 42203 110435626
Eosinophilia 29.04 10.31 11 111459 57925 110419904
Appetite disorder 28.77 10.31 42 111428 9727 110468102
Serum ferritin decreased 28.64 10.31 24 111446 2990 110474839
Arthritis 28.48 10.31 276 111194 167310 110310519
Carbuncle 28.47 10.31 18 111452 1449 110476380
Full blood count abnormal 28.43 10.31 122 111348 55930 110421899
Cytokine release syndrome 28.21 10.31 18 111452 70288 110407541
Blood albumin decreased 28.12 10.31 76 111394 27576 110450253
Skin disorder 27.92 10.31 101 111369 42812 110435017
Dry skin 27.84 10.31 195 111275 107458 110370371
Therapeutic response shortened 27.80 10.31 79 111391 29504 110448325
Rhinorrhoea 27.76 10.31 188 111282 102478 110375351
Agranulocytosis 27.37 10.31 14 111456 61746 110416083
Neutrophil count decreased 27.37 10.31 50 111420 120891 110356938
Uterine perforation 27.15 10.31 34 111436 6806 110471023
Bowel movement irregularity 27.15 10.31 36 111434 7624 110470205
Rhabdomyolysis 27.05 10.31 50 111420 120351 110357478
Pancytopenia 26.99 10.31 114 111356 209499 110268330
Delirium 26.98 10.31 60 111410 134965 110342864
Pericoronitis 26.88 10.31 9 111461 160 110477669
Delivery 26.50 10.31 15 111455 986 110476843
Hyponatraemia 26.43 10.31 121 111349 217532 110260297
Complications of bone marrow transplant 26.35 10.31 13 111457 645 110477184
Night sweats 25.59 10.31 61 111409 133922 110343907
Arthritis infective 25.32 10.31 41 111429 10388 110467441
Medication error 25.26 10.31 42 111428 105324 110372505
Cough 25.13 10.31 626 110844 461015 110016814
Injection site pain 25.03 10.31 282 111188 177640 110300189
Myringotomy 25.03 10.31 6 111464 28 110477801
Full blood count decreased 24.79 10.31 80 111390 32019 110445810
Liver disorder 24.68 10.31 68 111402 142175 110335654
Skin ulcer 24.59 10.31 128 111342 63517 110414312
Embedded device 24.48 10.31 25 111445 4008 110473821
Loss of therapeutic response 23.88 10.31 20 111450 2490 110475339
Dermatitis atopic 23.80 10.31 68 111402 25473 110452356
Bone density decreased 23.76 10.31 51 111419 15991 110461838
Hypothalamo-pituitary disorder 23.67 10.31 21 111449 2825 110475004
Parkinsonism 23.59 10.31 62 111408 22125 110455704
Lupus-like syndrome 23.57 10.31 6 111464 40786 110437043
Treatment failure 23.54 10.31 173 111297 277061 110200768
Cardiac arrest 23.52 10.31 110 111360 196643 110281186
Arthropod bite 23.45 10.31 38 111432 9633 110468196
Nausea 23.20 10.31 1492 109978 1234198 109243631
Vision blurred 23.17 10.31 215 111255 128807 110349022
Faeces soft 23.15 10.31 41 111429 11169 110466660
Fistula 23.08 10.31 49 111421 15250 110462579
Cholestasis 22.66 10.31 19 111451 64499 110413330
Maternal exposure before pregnancy 22.52 10.31 32 111438 7233 110470596
Premature separation of placenta 22.51 10.31 16 111454 1564 110476265
Lower limb fracture 22.09 10.31 26 111444 75322 110402507
Hypercalcaemia 21.73 10.31 99 111371 46558 110431271
Device interaction 21.68 10.31 12 111458 755 110477074
Blood creatine phosphokinase increased 21.66 10.31 25 111445 73052 110404777
Drug specific antibody present 21.63 10.31 34 111436 8400 110469429
Rash maculo-papular 21.34 10.31 26 111444 74196 110403633
Road traffic accident 21.23 10.31 48 111422 107350 110370479
Diarrhoea haemorrhagic 21.22 10.31 48 111422 15591 110462238
Hepatosplenic T-cell lymphoma 21.17 10.31 13 111457 994 110476835
Hepatic enzyme increased 21.11 10.31 214 111256 320678 110157151
Rash pruritic 21.05 10.31 170 111300 97899 110379930
Dizziness 21.02 10.31 882 110588 697311 109780518
Preterm premature rupture of membranes 20.80 10.31 15 111455 1500 110476329
Depressed level of consciousness 20.75 10.31 52 111418 112226 110365603
Intermenstrual bleeding 20.70 10.31 30 111440 6904 110470925
Abdominal pain lower 20.36 10.31 83 111387 37200 110440629
Dyschezia 20.26 10.31 22 111448 3785 110474044
Bronchopulmonary aspergillosis 20.19 10.31 3 111467 29860 110447969
Sopor 19.95 10.31 6 111464 36540 110441289
Sinus pain 19.87 10.31 27 111443 5852 110471977
Cerebral infarction 19.82 10.31 14 111456 51824 110426005
Hip fracture 19.79 10.31 79 111391 35072 110442757
Monoclonal immunoglobulin present 19.67 10.31 18 111452 2522 110475307
Pre-eclampsia 19.65 10.31 33 111437 8617 110469212
Intestinal stenosis 19.62 10.31 24 111446 4691 110473138
Haemophagocytic lymphohistiocytosis 19.52 10.31 4 111466 31555 110446274
Acute myeloid leukaemia 19.50 10.31 7 111463 38103 110439726
Vascular device infection 19.49 10.31 48 111422 16464 110461365
Malignant neoplasm progression 19.48 10.31 100 111370 174467 110303362
Rectal tenesmus 19.44 10.31 17 111453 2245 110475584
Drug reaction with eosinophilia and systemic symptoms 19.42 10.31 33 111437 82062 110395767
Multiple organ dysfunction syndrome 19.22 10.31 83 111387 151627 110326202
Red blood cell count decreased 19.20 10.31 123 111347 65800 110412029
Cytomegalovirus infection 19.16 10.31 16 111454 54428 110423401
Hypophosphataemia 19.02 10.31 75 111395 33107 110444722
Agitation 18.90 10.31 55 111415 112996 110364833
Serotonin syndrome 18.90 10.31 19 111451 59134 110418695
Retching 18.86 10.31 58 111412 22624 110455205
Haemoglobin abnormal 18.59 10.31 33 111437 9005 110468824
Loss of personal independence in daily activities 18.55 10.31 232 111238 149788 110328041
Skin discolouration 18.51 10.31 98 111372 48948 110428881
Hypokalaemia 18.44 10.31 108 111362 182340 110295489
Haematocrit decreased 18.43 10.31 122 111348 65995 110411834
Sedation 18.41 10.31 26 111444 69657 110408172
Complication of device removal 18.39 10.31 23 111447 4597 110473232
Premature rupture of membranes 18.33 10.31 23 111447 4614 110473215
Cognitive disorder 18.22 10.31 38 111432 87473 110390356
Onychomycosis 18.20 10.31 8 111462 38523 110439306
Intentional product use issue 18.20 10.31 351 111119 247555 110230274
Lower respiratory tract infection 18.18 10.31 157 111313 242949 110234880
Toxic skin eruption 18.07 10.31 3 111467 27512 110450317
Malabsorption 18.03 10.31 27 111443 6398 110471431
Small intestinal stenosis 18.03 10.31 13 111457 1300 110476529
Bone marrow failure 18.01 10.31 19 111451 57829 110420000
Joint space narrowing 17.97 10.31 11 111459 836 110476993
Breast cancer stage II 17.94 10.31 3 111467 27372 110450457
Stress at work 17.92 10.31 13 111457 1312 110476517
Overweight 17.90 10.31 27 111443 6437 110471392
Neoplasm skin 17.90 10.31 19 111451 3185 110474644
Neuroleptic malignant syndrome 17.87 10.31 6 111464 34053 110443776
Postpartum haemorrhage 17.87 10.31 15 111455 1874 110475955
Hypersensitivity 17.83 10.31 293 111177 403705 110074124
Chorea 17.75 10.31 19 111451 3216 110474613
Posterior reversible encephalopathy syndrome 17.70 10.31 6 111464 33855 110443974
Serum ferritin 17.70 10.31 3 111467 0 110477829
Heart rate irregular 17.69 10.31 75 111395 34199 110443630
Limb injury 17.63 10.31 80 111390 37556 110440273
Product quality issue 17.45 10.31 32 111438 77267 110400562
Pulmonary arterial hypertension 17.38 10.31 72 111398 32496 110445333
Accidental overdose 17.32 10.31 16 111454 51818 110426011
Hot flush 17.30 10.31 120 111350 65916 110411913
Kidney infection 17.29 10.31 61 111409 25538 110452291
Polymenorrhoea 17.26 10.31 12 111458 1132 110476697
Infection 17.22 10.31 259 111211 361941 110115888
Natural killer cell count 17.18 10.31 4 111466 16 110477813
Extrapyramidal disorder 17.16 10.31 4 111466 28863 110448966
Poisoning deliberate 17.00 10.31 3 111467 26328 110451501
Skin warm 16.99 10.31 32 111438 9138 110468691
Localised infection 16.92 10.31 87 111383 42961 110434868
Blood pressure systolic increased 16.81 10.31 142 111328 82849 110394980
Chronic kidney disease 16.78 10.31 133 111337 76158 110401671
Hypervolaemia 16.77 10.31 96 111374 49364 110428465
Weight increased 16.69 10.31 547 110923 419097 110058732
Intercepted medication error 16.60 10.31 12 111458 1204 110476625
Septic shock 16.59 10.31 92 111378 157436 110320393
Feeling abnormal 16.53 10.31 265 111205 180446 110297383
Reflux gastritis 16.51 10.31 13 111457 1483 110476346
Allergy to metals 16.46 10.31 10 111460 750 110477079
Tendon injury 16.37 10.31 16 111454 2433 110475396
Erythema 16.37 10.31 397 111073 291050 110186779
Amegakaryocytic thrombocytopenia 16.29 10.31 4 111466 21 110477808
Acne 16.27 10.31 72 111398 33448 110444381
Pallor 16.23 10.31 105 111365 56362 110421467
Splenomegaly 16.23 10.31 58 111412 24440 110453389
Hospitalisation 16.20 10.31 217 111253 142276 110335553
Dyspnoea 16.19 10.31 1310 110160 1105562 109372267
Body height decreased 16.13 10.31 34 111436 10529 110467300
Electrocardiogram QT prolonged 16.12 10.31 56 111414 108904 110368925
Thrombosis 16.09 10.31 174 111296 108488 110369341
Dysmenorrhoea 16.04 10.31 19 111451 3591 110474238
Viral infection 16.01 10.31 100 111370 53039 110424790
Ischaemic stroke 15.97 10.31 11 111459 41252 110436577
Uterine atony 15.95 10.31 7 111463 265 110477564
Abscess 15.67 10.31 62 111408 27407 110450422
Cerebral haemorrhage 15.48 10.31 26 111444 64942 110412887
Early satiety 15.37 10.31 14 111456 1949 110475880
COVID-19 15.37 10.31 339 111131 244721 110233108
Urticaria 14.81 10.31 229 111241 318628 110159201
Allodynia 14.66 10.31 14 111456 2069 110475760
Autonomic dysreflexia 14.64 10.31 8 111462 491 110477338
Skin induration 14.58 10.31 20 111450 4375 110473454
Hip arthroplasty 14.57 10.31 21 111449 55792 110422037
Heart valve replacement 14.53 10.31 11 111459 1185 110476644
Hernia 14.52 10.31 48 111422 19452 110458377
Feeding disorder 14.51 10.31 51 111419 21311 110456518
Infusion related reaction 14.42 10.31 284 111186 380878 110096951
Amnesia 14.40 10.31 56 111414 105352 110372477
Muscular weakness 14.22 10.31 171 111299 248297 110229532
Musculoskeletal pain 14.22 10.31 117 111353 182906 110294923
Vaginal infection 14.20 10.31 25 111445 6779 110471050
Foreign body in reproductive tract 14.19 10.31 10 111460 964 110476865
Device breakage 14.16 10.31 38 111432 13731 110464098
Small intestinal obstruction 14.01 10.31 67 111403 32146 110445683
Influenza 14.01 10.31 244 111226 168857 110308972
Blood loss anaemia 13.99 10.31 45 111425 17980 110459849
Peritonitis bacterial 13.92 10.31 32 111438 10501 110467328
Vein rupture 13.91 10.31 15 111455 2560 110475269
Vitamin D decreased 13.88 10.31 35 111435 12180 110465649
Transferrin saturation increased 13.78 10.31 6 111464 223 110477606
Bronchiectasis 13.76 10.31 10 111460 36483 110441346
Internal haemorrhage 13.76 10.31 31 111439 10040 110467789
Vascular stenosis 13.75 10.31 9 111461 769 110477060
Blood pressure diastolic decreased 13.74 10.31 72 111398 35813 110442016
Pneumonitis 13.71 10.31 36 111434 76495 110401334
Dry mouth 13.70 10.31 132 111338 199816 110278013
Chills 13.70 10.31 269 111201 190311 110287518
Therapeutic product effect decreased 13.66 10.31 169 111301 244147 110233682
Coeliac disease 13.65 10.31 14 111456 43173 110434656
Stress 13.49 10.31 164 111306 105184 110372645
Pelvic pain 13.48 10.31 41 111429 15901 110461928
Foetal growth restriction 13.47 10.31 16 111454 3034 110474795
Transferrin saturation decreased 13.40 10.31 11 111459 1332 110476497
Crystal urine present 13.39 10.31 13 111457 1961 110475868
Mydriasis 13.31 10.31 3 111467 22154 110455675
Gamma-glutamyltransferase increased 13.29 10.31 26 111444 61283 110416546
Chronic spontaneous urticaria 13.29 10.31 13 111457 1980 110475849
Drug tolerance decreased 13.25 10.31 59 111411 27481 110450348
Enterobacter pneumonia 13.20 10.31 8 111462 597 110477232
Drug ineffective for unapproved indication 13.19 10.31 56 111414 102782 110375047
Uterine infection 13.17 10.31 7 111463 406 110477423
Vessel puncture site pain 13.17 10.31 4 111466 51 110477778
Fall 13.02 10.31 738 110732 602744 109875085
Rectal haemorrhage 13.01 10.31 181 111289 119652 110358177
Cervical polyp 12.92 10.31 6 111464 260 110477569
Wrist deformity 12.89 10.31 16 111454 3173 110474656
Small intestine ulcer 12.83 10.31 9 111461 862 110476967
Transaminases increased 12.80 10.31 28 111442 63362 110414467
Respiratory failure 12.79 10.31 147 111323 215185 110262644
Chest discomfort 12.70 10.31 246 111224 173602 110304227
Coronary artery disease 12.63 10.31 34 111436 71656 110406173
Aspergillus infection 12.61 10.31 5 111465 25611 110452218
Dysarthria 12.60 10.31 43 111427 84078 110393751
Aplasia pure red cell 12.55 10.31 29 111441 9549 110468280
Infusion site bruising 12.54 10.31 17 111453 3677 110474152
Dyslipidaemia 12.52 10.31 40 111430 15925 110461904
Hyperparathyroidism secondary 12.44 10.31 16 111454 3288 110474541
Infusion site haemorrhage 12.44 10.31 19 111451 4579 110473250
Myositis 12.44 10.31 8 111462 31108 110446721
Platelet count increased 12.36 10.31 56 111414 26278 110451551
Cystitis 12.34 10.31 111 111359 65925 110411904
Maternal exposure timing unspecified 12.32 10.31 3 111467 21010 110456819
Hepatocellular injury 12.31 10.31 20 111450 50622 110427207
Body temperature fluctuation 12.26 10.31 17 111453 3756 110474073
Injection site erythema 12.23 10.31 147 111323 94029 110383800
Faeces hard 12.14 10.31 18 111452 4228 110473601
Muscle spasticity 12.10 10.31 11 111459 35904 110441925
Myopathy 12.08 10.31 5 111465 24955 110452874
Vasculitis 12.07 10.31 11 111459 35862 110441967
Red blood cells urine positive 12.07 10.31 20 111450 5165 110472664
Anal ulcer 12.07 10.31 12 111458 1864 110475965
Twin pregnancy 12.06 10.31 9 111461 949 110476880
Appendicectomy 12.06 10.31 16 111454 3391 110474438
Gastroduodenal haemorrhage 12.04 10.31 6 111464 304 110477525
Sciatica 12.04 10.31 50 111420 92349 110385480
Malaise 11.97 10.31 808 110662 671011 109806818
Deafness 11.94 10.31 56 111414 26653 110451176
Mucosal inflammation 11.93 10.31 53 111417 96088 110381741
Ventricular tachycardia 11.92 10.31 20 111450 49989 110427840
Blood glucose decreased 11.87 10.31 60 111410 29428 110448401
Pancreatitis acute 11.86 10.31 27 111443 60247 110417582
Tooth infection 11.77 10.31 49 111421 22167 110455662
Congenital cytomegalovirus infection 11.74 10.31 3 111467 19 110477810
Premature baby 11.67 10.31 19 111451 4836 110472993
Dyspnoea exertional 11.63 10.31 158 111312 103902 110373927
Wound infection bacterial 11.57 10.31 9 111461 1009 110476820
Anion gap 11.50 10.31 12 111458 1973 110475856
Anal fistula 11.49 10.31 26 111444 8447 110469382
Hepatic hypertrophy 11.49 10.31 3 111467 21 110477808
Red blood cell sedimentation rate increased 11.41 10.31 125 111345 78177 110399652
Sinus disorder 11.41 10.31 64 111406 32664 110445165
Disorientation 11.37 10.31 35 111435 70636 110407193
Normal newborn 11.37 10.31 48 111422 21848 110455981
Sinus tachycardia 11.36 10.31 17 111453 44476 110433353
Muscle rigidity 11.34 10.31 5 111465 24026 110453803
Ileostomy 11.32 10.31 13 111457 2379 110475450
Exostosis 11.31 10.31 18 111452 45938 110431891
Abortion spontaneous 11.27 10.31 66 111404 34216 110443613
Dystonia 11.21 10.31 6 111464 25799 110452030
Blood growth hormone increased 11.19 10.31 9 111461 1059 110476770
Proctalgia 11.17 10.31 34 111436 13188 110464641
Acute respiratory distress syndrome 11.16 10.31 23 111447 53175 110424654
Delayed haemolytic transfusion reaction 11.14 10.31 3 111467 24 110477805
Eosinophilic pneumonia chronic 11.11 10.31 7 111463 560 110477269
Encephalopathy 11.11 10.31 43 111427 81012 110396817
Acute generalised exanthematous pustulosis 11.05 10.31 4 111466 21660 110456169
Blood pressure systolic abnormal 11.04 10.31 52 111418 24798 110453031
Respiratory disorder 11.03 10.31 36 111434 71346 110406483
Skin fibrosis 10.99 10.31 10 111460 1390 110476439
Hemiparesis 10.99 10.31 17 111453 43886 110433943
Left ventricular dysfunction 10.91 10.31 5 111465 23488 110454341
Tumour lysis syndrome 10.90 10.31 9 111461 30792 110447037
Agitated depression 10.89 10.31 7 111463 580 110477249
Neutropenic sepsis 10.87 10.31 9 111461 30737 110447092
Hyperthermia 10.73 10.31 4 111466 21268 110456561
Pain 10.71 10.31 1109 110361 953846 109523983
COVID-19 pneumonia 10.69 10.31 13 111457 37130 110440699
Impaired quality of life 10.66 10.31 59 111411 29958 110447871
Autoimmune lung disease 10.65 10.31 5 111465 222 110477607
Angina pectoris 10.64 10.31 30 111440 62265 110415564
Insurance issue 10.62 10.31 29 111441 10583 110467246
Mastitis 10.61 10.31 13 111457 2545 110475284
Lymphopenia 10.60 10.31 15 111455 40155 110437674
Obstruction 10.56 10.31 20 111450 5732 110472097
Rash macular 10.55 10.31 71 111399 38615 110439214
Anal stenosis 10.52 10.31 7 111463 615 110477214
Acute myocardial infarction 10.51 10.31 46 111424 83731 110394098
Bronchospasm 10.50 10.31 9 111461 30230 110447599
Palindromic rheumatism 10.45 10.31 6 111464 405 110477424
Human chorionic gonadotropin negative 10.45 10.31 3 111467 31 110477798
Back injury 10.36 10.31 20 111450 47379 110430450

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A11AA01 ALIMENTARY TRACT AND METABOLISM
VITAMINS
MULTIVITAMINS, COMBINATIONS
Multivitamins with minerals
ATC B03AE01 BLOOD AND BLOOD FORMING ORGANS
ANTIANEMIC PREPARATIONS
IRON PREPARATIONS
Iron in other combinations
ATC B03AE02 BLOOD AND BLOOD FORMING ORGANS
ANTIANEMIC PREPARATIONS
IRON PREPARATIONS
Iron in other combinations
ATC B03AE03 BLOOD AND BLOOD FORMING ORGANS
ANTIANEMIC PREPARATIONS
IRON PREPARATIONS
Iron in other combinations
ATC B03AE04 BLOOD AND BLOOD FORMING ORGANS
ANTIANEMIC PREPARATIONS
IRON PREPARATIONS
Iron in other combinations
MeSH PA D014131 Trace Elements
MeSH PA D018977 Micronutrients
CHEBI has role CHEBI:27027 trace elements
CHEBI has role CHEBI:76971 Escherichia coli metabolites

Related Drugs by ATC class:

B03AE Iron in other combinations 2 drugs
cyanocobalaminfolic acid

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Anemia of prematurity indication 47100003 DOID:11243
Megaloblastic anemia due to folate deficiency indication 85649008 DOID:14026
Iron deficiency anemia indication 87522002
Magnetic resonance imaging of liver indication 241622002
Peptic ulcer contraindication 13200003 DOID:750
Gastroenteritis contraindication 25374005 DOID:2326
Hemosiderosis contraindication 39011001 DOID:12119
Hemolytic anemia contraindication 61261009 DOID:583
Ulcerative colitis contraindication 64766004 DOID:8577
Diverticular disease contraindication 397881000
Hemochromatosis contraindication 399187006 DOID:2352
Repeated Blood Transfusions contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4017653 VUID
N0000146032 NUI
D09736 KEGG_DRUG
4017653 VANDF
4021247 VANDF
4021883 VANDF
C0337439 UMLSCUI
CHEBI:18248 CHEBI
D007501 MESH_DESCRIPTOR_UI
DB01592 DRUGBANK_ID
E1UOL152H7 UNII
23925 PUBCHEM_CID
262150 RXNORM
20159 MMSL
224113 MMSL
30873 MMSL
30874 MMSL
34448 MMSL
6958 MMSL
7441 MMSL
8219 MMSL
NOCODE MMSL
d04432 MMSL
000828 NDDF
007431 NDDF
30729008 SNOMEDCT_US
32954005 SNOMEDCT_US
3829006 SNOMEDCT_US
714781004 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Ferralet 90 HUMAN PRESCRIPTION DRUG LABEL 5 0178-0089 TABLET, FILM COATED 90 mg ORAL unapproved drug other 17 sections
NataFort HUMAN PRESCRIPTION DRUG LABEL 10 0178-0716 TABLET 60 mg ORAL Unapproved drug other 12 sections
Citranatal Harmony 2.1 HUMAN PRESCRIPTION DRUG LABEL 2 0178-0797 CAPSULE, GELATIN COATED 29 mg ORAL unapproved drug other 10 sections
CitraNatal 90 DHA HUMAN PRESCRIPTION DRUG LABEL 16 0178-0821 TABLET 85 mg ORAL unapproved drug other 11 sections
CitraNatal 90 DHA HUMAN OTC DRUG LABEL 14 0178-0829 TABLET 90 mg ORAL Unapproved drug other 11 sections
CitraNatal Rx HUMAN PRESCRIPTION DRUG LABEL 13 0178-0858 TABLET 27 mg ORAL Unapproved drug other 12 sections
CitraNatal Rx HUMAN PRESCRIPTION DRUG LABEL 14 0178-0859 TABLET 27 mg ORAL Unapproved drug other 9 sections
CitraNatal DHA HUMAN OTC DRUG LABEL 14 0178-0898 TABLET 27 mg ORAL Unapproved drug other 11 sections
VitafolOne HUMAN PRESCRIPTION DRUG LABEL 16 0642-0070 CAPSULE, GELATIN COATED 29 mg ORAL unapproved drug other 14 sections
Select OB HUMAN PRESCRIPTION DRUG LABEL 15 0642-0077 TABLET, CHEWABLE 29 mg ORAL UNAPPROVED DRUG OTHER 14 sections
Vitafol OBCaplet HUMAN PRESCRIPTION DRUG LABEL 15 0642-0079 TABLET 65 mg ORAL unapproved drug other 14 sections
Vitafol Plus HUMAN PRESCRIPTION DRUG LABEL 17 0642-0092 CAPSULE, LIQUID FILLED 27 mg ORAL UNAPPROVED DRUG OTHER 13 sections
VitafolUltra HUMAN PRESCRIPTION DRUG LABEL 17 0642-0093 CAPSULE, LIQUID FILLED 29 mg ORAL unapproved drug other 13 sections
Select OB HUMAN PRESCRIPTION DRUG LABEL 15 0642-0120 TABLET, CHEWABLE 29 mg ORAL UNAPPROVED DRUG OTHER 13 sections
Reaphirm Plant Source DHA HUMAN PRESCRIPTION DRUG LABEL 16 0642-3010 CAPSULE, GELATIN COATED 29 mg ORAL unapproved drug other 7 sections
Vitafol Fe Plus HUMAN PRESCRIPTION DRUG LABEL 17 0642-7473 CAPSULE, LIQUID FILLED 90 mg ORAL unapproved drug other 14 sections
Polysaccharide-Iron HUMAN OTC DRUG LABEL 1 17714-077 CAPSULE 150 mg ORAL unapproved drug other 10 sections
Centratex HUMAN PRESCRIPTION DRUG LABEL 13 23359-100 CAPSULE 106 mg ORAL unapproved drug other 13 sections
Nestabs ONE HUMAN PRESCRIPTION DRUG LABEL 10 50967-410 CAPSULE, GELATIN COATED 38 mg ORAL unapproved drug other 12 sections
Concept OB HUMAN PRESCRIPTION DRUG LABEL 15 52747-620 CAPSULE 42.50 mg ORAL unapproved drug other 13 sections
Concept DHA HUMAN PRESCRIPTION DRUG LABEL 15 52747-621 CAPSULE, LIQUID FILLED 17.50 mg ORAL unapproved drug other 7 sections
7 Heavy Metal Detox HUMAN OTC DRUG LABEL 61 55146-007 LIQUID 12 [hp_X] ORAL unapproved homeopathic 9 sections
1 Detoxification HUMAN OTC DRUG LABEL 81 55146-011 LIQUID 12 [hp_X] ORAL unapproved homeopathic 9 sections
Davimet with Iron HUMAN PRESCRIPTION DRUG LABEL 12 59088-160 TABLET 11 mg ORAL unapproved drug other 13 sections
Nephron FA HUMAN PRESCRIPTION DRUG LABEL 10 59528-4456 TABLET, COATED 66 mg ORAL unapproved drug other 4 sections
PreNatal Vitamins Plus HUMAN PRESCRIPTION DRUG LABEL 14 63629-3545 TABLET 27 mg ORAL Unapproved drug other 9 sections
Chavita 4 HUMAN OTC DRUG LABEL 7 66343-009 LIQUID 50 [hp_C] ORAL Unapproved homeopathic 10 sections
Nephron FA HUMAN PRESCRIPTION DRUG LABEL 10 68151-3063 TABLET, COATED 66 mg ORAL unapproved drug other 4 sections
Prenatal Vitamins Plus Low Iron HUMAN PRESCRIPTION DRUG LABEL 15 68151-5878 TABLET 27 mg ORAL Unapproved drug other 9 sections
REAL SUMMER HUMAN OTC DRUG LABEL 1 69449-1010 PATCH 0.76 g TOPICAL unapproved drug other 10 sections