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norgestrienone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| steroids, progestogens | 3205 | 848-21-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A synthetic steroid with progestational and contraceptive activities.
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,ITK,JAK2,JAK3,MAP2K6,MAP3K14,MAP3K7,MAPK10,MAPK7,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIM2,PRKDC,STK33,SYK,TEK,TGFBR1,TTK,ZAP70 | 38 | |||
| kinase-selectivity-class | GRK2,MAP2K6,MAP3K14 | 3 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | G03AC07 | GENITO URINARY SYSTEM AND SEX HORMONES SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE Progestogens |
| MeSH PA | D003271 | Contraceptive Agents, Female |
| MeSH PA | D003280 | Contraceptives, Oral, Synthetic |
| MeSH PA | D012102 | Reproductive Control Agents |
| CHEBI has role | CHEBI:50114 | estrogen |
Related Drugs by ATC class:
G03AC Progestogens 9 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.57 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000167402 | NUI |
| D07220 | KEGG_DRUG |
| C0028369 | UMLSCUI |
| CHEBI:135231 | CHEBI |
| CHEMBL1908319 | ChEMBL_ID |
| DB13563 | DRUGBANK_ID |
| D009645 | MESH_DESCRIPTOR_UI |
| 13313 | PUBCHEM_CID |
| 2373 | INN_ID |
| 89386PYU9O | UNII |
| 7519 | RXNORM |
| 005626 | NDDF |
| 89386PYU9O | INXIGHT DRUGS |
Pharmaceutical products:
None