azidamfenicol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
antibacterial antibiotics, chloramphenicol analogues 3011 13838-08-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • azidamfenicol
  • azidamphenicol
  • azidoamphenicol
  • Molecular weight: 295.26
  • Formula: C11H13N5O5
  • CLOGP: 0.90
  • LIPINSKI: 0
  • HAC: 10
  • HDO: 3
  • TPSA: 144.81
  • ALOGS: -2.39
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AKT2,AKT3,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,IGF1R,ITK,JAK2,JAK3,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK8,MAPK9,MAPKAPK2,MET,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1,ZAP70 55
kinase-selectivity-class AXL,GRK2,MAP2K6,MAPK7,STK33,TEK,TTK 7
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC S01AA25 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFECTIVES
Antibiotics
CHEBI has role CHEBI:66981 ophthalmology drug

Related Drugs by ATC class:

S01AA Antibiotics 27 drugs
amikacinampicillinazithromycinbacitracinbenzylpenicillincefmenoximecefuroximechloramphenicolchlortetracyclinedibekacindihydrostreptomycinerythromycin show all 27 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.37 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07411 KEGG_DRUG
C0771992 UMLSCUI
CHEBI:135238 CHEBI
CHEMBL3989525 ChEMBL_ID
DB13294 DRUGBANK_ID
62858 PUBCHEM_CID
12397 IUPHAR_LIGAND_ID
C004450 MESH_SUPPLEMENTAL_RECORD_UI
1703 INN_ID
40257685LM UNII
006603 NDDF

Pharmaceutical products:

None