tosufloxacin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibacterials, nalidixic acid derivatives 2710 100490-36-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tosufloxacin tosylate
  • tosufloxacin tosilate hydrate
  • tosufloxacin
  • tosulfloxacin
  • tosufloxacin tosilate
  • tosufloxacin hydrochloride
  • tosufloxacin HCl
quinolone anti-infective agent; structure given in first source
  • Molecular weight: 404.35
  • Formula: C19H15F3N4O3
  • CLOGP: -0.81
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 2
  • TPSA: 99.76
  • ALOGS: -3.72
  • ROTB: 3

Drug dosage:

DoseUnitRoute
0.45 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01MA22 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
QUINOLONE ANTIBACTERIALS
Fluoroquinolones
ATC S01AE09 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFECTIVES
Fluoroquinolones
CHEBI has role CHEBI:33281 antibiotics
CHEBI has role CHEBI:35441 antiinfective agents
CHEBI has role CHEBI:50908 agente hepatotoxico
CHEBI has role CHEBI:53559 topoisomerase IV inhibitors
CHEBI has role CHEBI:59517 DNA synthesis inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.92 acidic
pKa2 8.7 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02317 KEGG_DRUG
115964-29-9 SECONDARY_CAS_RN
C0076843 UMLSCUI
CHEBI:77573 CHEBI
CHEMBL273348 ChEMBL_ID
CHEMBL104270 ChEMBL_ID
DB16850 DRUGBANK_ID
C055185 MESH_SUPPLEMENTAL_RECORD_UI
5517 PUBCHEM_CID
6242 INN_ID
104051-69-6 SECONDARY_CAS_RN
GHJ553KQPS UNII
008167 NDDF
008169 NDDF

Pharmaceutical products:

None