amyl nitrite 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
NO2 - derivatives 205 8017-89-8

Description:

MoleculeDescription

Synonyms:

  • amyl nitrite
  • vaporole
  • nitramyl
  • amylnitrit
A vasodilator that is administered by inhalation. It is also used recreationally due to its supposed ability to induce euphoria and act as an aphrodisiac.
  • Molecular weight: 234.30
  • Formula: C10H22N2O4
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 38.66
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V03AB22 VARIOUS
ALL OTHER THERAPEUTIC PRODUCTS
ALL OTHER THERAPEUTIC PRODUCTS
Antidotes
CHEBI has role CHEBI:35620 vasodilator agents
CHEBI has role CHEBI:35674 antihypertensive drugs
MeSH PA D002317 Cardiovascular Agents
MeSH PA D014665 Vasodilator Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Toxic effect of cyanide indication 66207005
Angina pectoris off-label use 194828000
Glaucoma contraindication 23986001 DOID:1686
Orthostatic hypotension contraindication 28651003
Methemoglobinemia contraindication 38959009 DOID:10783
Benign intracranial hypertension contraindication 68267002 DOID:11459
Injury of head contraindication 82271004
Anemia contraindication 271737000 DOID:2355
Cerebral hemorrhage contraindication 274100004




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
22T8Z09XAK UNII
4017514 VUID
N0000145899 NUI
D00517 KEGG_DRUG
742 RXNORM
C0002711 UMLSCUI
CHEBI:55344 CHEBI
CHEMBL3833339 ChEMBL_ID
10026 PUBCHEM_CID
DB01612 DRUGBANK_ID
D000680 MESH_DESCRIPTOR_UI
3836 MMSL
4197 MMSL
d00666 MMSL
116655003 SNOMEDCT_US
387038004 SNOMEDCT_US
4017514 VANDF
000684 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Amyl Nitrite HUMAN PRESCRIPTION DRUG LABEL 1 46414-2222 INHALANT 0.30 g RESPIRATORY (INHALATION) unapproved drug other 13 sections