nicomorphine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| opioid receptor antagonists/agonists, morphinan derivates | 1918 | 639-48-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 30 | mg | O |
| 30 | mg | P |
| 30 | mg | R |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Macular degeneration | 69.10 | 68.74 | 14 | 255 | 11282 | 79732837 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | N02AA04 | NERVOUS SYSTEM ANALGESICS OPIOIDS Natural opium alkaloids |
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D002492 | Central Nervous System Depressants |
| MeSH PA | D009294 | Narcotics |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D018689 | Sensory System Agents |
| MeSH PA | D000701 | Analgesics, Opioid |
| FDA MoA | N0000175684 | Full Opioid Agonists |
| FDA EPC | N0000175690 | Opioid Agonist |
| CHEBI has role | CHEBI:35482 | narcotic analgesic |
| CHEBI has role | CHEBI:35620 | vasodilator agents |
| CHEBI has role | CHEBI:35703 | Xenobiotic |
| CHEBI has role | CHEBI:38867 | anaesthetic |
| CHEBI has role | CHEBI:55322 | mu-opioid agonists |
| CHEBI has role | CHEBI:76924 | plant metabolites |
| CHEBI has role | CHEBI:78298 | environmental contaminants |
| CHEBI has role | CHEBI:88188 | allergenic drug |
| CHEBI has role | CHEBI:176497 | geroprotectors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.18 | Basic |
| pKa2 | 3.27 | Basic |
| pKa3 | 2.65 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07285 | KEGG_DRUG |
| 4017530 | VANDF |
| C0068699 | UMLSCUI |
| CHEBI:135797 | CHEBI |
| CHEBI:17303 | CHEBI |
| MOI | PDB_CHEM_ID |
| CHEMBL2106851 | ChEMBL_ID |
| DB13454 | DRUGBANK_ID |
| C008549 | MESH_SUPPLEMENTAL_RECORD_UI |
| 789 | INN_ID |
| Y95FRL95FW | UNII |
| 5362460 | PUBCHEM_CID |
| 7052 | RXNORM |
| d00308 | MMSL |
| 001545 | NDDF |
| 373529000 | SNOMEDCT_US |
| 73572009 | SNOMEDCT_US |
| 96181009 | SNOMEDCT_US |
| C0026549 | UMLSCUI |
| DB00295 | DRUGBANK_ID |
| D009020 | MESH_DESCRIPTOR_UI |
| 5288826 | PUBCHEM_CID |
Pharmaceutical products:
None