DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
nicomorphine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
opioid receptor antagonists/agonists, morphinan derivates
1918
639-48-5
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
nicomorphine
morphine dinicotinate
Molecular weight: 495.54
Formula: C29H25N3O5
CLOGP: 2.76
LIPINSKI: 0
HAC: 8
HDO: 0
TPSA: 90.85
ALOGS: -3.84
ROTB: 6
Status: OFP
Legend:
OFP - off patent
OFM - off market
ONP - on patent
Drug dosage:
Dose
Unit
Route
30
mg
O
30
mg
P
30
mg
R
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
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MedDRA adverse event term
Likelihood ratio
Likelihood ratio threshold
Patients taking drug having adverse event
Patients taking drug not having adverse event
Patients not taking drug having adverse event
Patients not taking drug not having adverse event
Macular degeneration
69.10
68.74
14
255
11282
79732837
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FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
N02AA04
NERVOUS SYSTEM
ANALGESICS
OPIOIDS
Natural opium alkaloids
CHEBI has role
CHEBI:35482
narcotic analgesic
CHEBI has role
CHEBI:35620
vasodilator agents
CHEBI has role
CHEBI:35703
Xenobiotic
CHEBI has role
CHEBI:38867
anaesthetic
CHEBI has role
CHEBI:55322
mu-opioid agonists
CHEBI has role
CHEBI:76924
plant metabolites
CHEBI has role
CHEBI:78298
environmental contaminants
CHEBI has role
CHEBI:88188
allergenic drug
CHEBI has role
CHEBI:176497
geroprotectors
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
8.18
Basic
pKa2
3.27
Basic
pKa3
2.65
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
MOI
PDB_CHEM_ID
001545
NDDF
373529000
SNOMEDCT_US
4017530
VANDF
5288826
PUBCHEM_CID
5362460
PUBCHEM_CID
7052
RXNORM
73572009
SNOMEDCT_US
789
INN_ID
96181009
SNOMEDCT_US
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Pharmaceutical products:
None
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nicomorphine