DrugCentral 2023 ๐
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 ๐
2022 Update-Veterinary Drugs & Uses
Search
Structure ๐
Similarity ๐
Smart API
Redial
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Download
L1000
FAQ
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
mydecamycin ๐ถ
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
antibiotics, produced by Streptomyces strains
1861
35457-80-8
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
mydecamycin
aboren
Espinomycin A
Medecamycin A1
medemycin
Medemycin A1
midecamycin
Midecamycin A1
Platenomycin B1
rubimycin
turimycin
macrolide antibiotic from Streptomyces hygroscopicus JA 6599; structure
Molecular weight: 813.98
Formula: C41H67NO15
CLOGP: 3.27
LIPINSKI: 2
HAC: 16
HDO: 3
TPSA: 206.05
ALOGS: -3.94
ROTB: 14
Drug dosage:
Dose
Unit
Route
1.20
g
O
1
g
P
ADMET properties:
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Property
Value
Reference
MRTD (Maximum Recommended Therapeutic Daily Dose)
31.59 ยตM/kg/day
Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
J01FA03
ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
Macrolides
MeSH PA
D000900
Anti-Bacterial Agents
MeSH PA
D000890
Anti-Infective Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
๐ถ Veterinary Drug Use
None
๐ถ Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
12.8
acidic
pKa2
13.95
acidic
pKa3
7.88
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
005381
NDDF
30005
RXNORM
3461
INN_ID
5282169
PUBCHEM_CID
703378009
SNOMEDCT_US
703379001
SNOMEDCT_US
C0066531
UMLSCUI
C011138
MESH_SUPPLEMENTAL_RECORD_UI
C026483
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:31845
CHEBI
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Pharmaceutical products:
None
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mydecamycin