micronomicin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
aminoglycosides, antibiotics obtained from various Micromonospora 1801 52093-21-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • micronomicin sulfate
  • micronomicin
  • Gentamicin C2b
  • sagamicin
  • santemycin
DE 020 & DE 020 eyedrops both consist of KW 1062, benzalkonium chloride, sodium chloride, sodium hydroxide & distilled water pH 7.4; RN given refers to parent cpd; see also record for gentamicin C; structure
  • Molecular weight: 463.58
  • Formula: C20H41N5O7
  • CLOGP: -2.11
  • LIPINSKI: 2
  • HAC: 12
  • HDO: 8
  • TPSA: 199.73
  • ALOGS: -1.42
  • ROTB: 7

Drug dosage:

None

ADMET properties:

PropertyValueReference
Vd (Volume of distribution) 0.15 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 1.10 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 2.10 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC S01AA22 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFECTIVES
Antibiotics
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.11 Basic
pKa2 8.5 Basic
pKa3 7.09 Basic
pKa4 6.48 Basic
pKa5 5.55 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01821 KEGG_DRUG
66803-19-8 SECONDARY_CAS_RN
C0066520 UMLSCUI
CHEBI:31844 CHEBI
CHEMBL373081 ChEMBL_ID
DB13274 DRUGBANK_ID
C037545 MESH_SUPPLEMENTAL_RECORD_UI
12162 IUPHAR_LIGAND_ID
5036 INN_ID
S9AZ0R40QV UNII
3037206 PUBCHEM_CID
236199 RXNORM
005379 NDDF
005380 NDDF

Pharmaceutical products:

None