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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
medifoxamine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
1656
32359-34-5
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
medifoxamine
Molecular weight: 257.33
Formula: C16H19NO2
CLOGP: 3.38
LIPINSKI: 0
HAC: 3
HDO: 0
TPSA: 21.70
ALOGS: -2.90
ROTB: 6
Drug dosage:
None
ADMET properties:
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Property
Value
Reference
t_half (Half-life)
4.40 hours
Lombardo F, Berellini G, Obach RS
BA (Bioavailability)
21 %
Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
Vd (Volume of distribution)
2.80 L/kg
Lombardo F, Berellini G, Obach RS
CL (Clearance)
13.70 mL/min/kg
Lombardo F, Berellini G, Obach RS
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
N06AX13
NERVOUS SYSTEM
PSYCHOANALEPTICS
ANTIDEPRESSANTS
Other antidepressants
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
7.35
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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entries
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ID
Source
005661
NDDF
29434
RXNORM
36109
PUBCHEM_CID
3759
INN_ID
C0065858
UMLSCUI
C034065
MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL85231
ChEMBL_ID
D07341
KEGG_DRUG
DB13219
DRUGBANK_ID
KWU7C2A1NT
UNII
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Pharmaceutical products:
None
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medifoxamine