ephedrine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| sympathomimetics | 1024 | 299-42-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 50 | mg | P |
| 8 | mg | N |
| 50 | mg | O |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| S (Water solubility) | 56.18 mg/mL | Bocci G, Oprea TI, Benet LZ |
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 3 | Bocci G, Oprea TI, Benet LZ |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Bradycardia | 125.93 | 32.45 | 55 | 1819 | 73172 | 63413976 |
| Hypotension | 94.94 | 32.45 | 72 | 1802 | 272532 | 63214616 |
| Exposure during pregnancy | 94.47 | 32.45 | 58 | 1816 | 155489 | 63331659 |
| Anterior spinal artery syndrome | 85.09 | 32.45 | 12 | 1862 | 113 | 63487035 |
| Maternal exposure during delivery | 84.28 | 32.45 | 17 | 1857 | 1483 | 63485665 |
| Anaphylactic shock | 68.94 | 32.45 | 26 | 1848 | 23607 | 63463541 |
| Spinal cord injury | 67.68 | 32.45 | 13 | 1861 | 880 | 63486268 |
| Mental status changes postoperative | 56.99 | 32.45 | 9 | 1865 | 191 | 63486957 |
| Cardio-respiratory arrest | 56.89 | 32.45 | 30 | 1844 | 59929 | 63427219 |
| Live birth | 56.42 | 32.45 | 23 | 1851 | 25607 | 63461541 |
| Confusion postoperative | 55.13 | 32.45 | 9 | 1865 | 237 | 63486911 |
| Rhythm idioventricular | 54.43 | 32.45 | 9 | 1865 | 257 | 63486891 |
| Drug reaction with eosinophilia and systemic symptoms | 50.27 | 32.45 | 23 | 1851 | 33813 | 63453335 |
| Cardiac arrest | 44.82 | 32.45 | 30 | 1844 | 92515 | 63394633 |
| Maternal exposure during pregnancy | 43.23 | 32.45 | 42 | 1832 | 220020 | 63267128 |
| Ventricular tachycardia | 37.46 | 32.45 | 16 | 1858 | 19963 | 63467185 |
| Stress cardiomyopathy | 37.27 | 32.45 | 13 | 1861 | 9437 | 63477711 |
| Eosinophilia | 35.46 | 32.45 | 16 | 1858 | 22740 | 63464408 |
| Metabolic alkalosis | 32.52 | 32.45 | 9 | 1865 | 3052 | 63484096 |
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Anaphylactic shock | 96.51 | 34.81 | 32 | 1272 | 15909 | 34939718 |
| Toxicity to various agents | 59.10 | 34.81 | 53 | 1251 | 200309 | 34755318 |
| Hypertonia neonatal | 47.27 | 34.81 | 9 | 1295 | 458 | 34955169 |
| Anaphylactic reaction | 46.22 | 34.81 | 23 | 1281 | 32278 | 34923349 |
| Locked-in syndrome | 45.31 | 34.81 | 8 | 1296 | 267 | 34955360 |
| Hyperthermia malignant | 43.12 | 34.81 | 11 | 1293 | 2166 | 34953461 |
| Agitation neonatal | 39.62 | 34.81 | 9 | 1295 | 1087 | 34954540 |
| Embolic stroke | 39.58 | 34.81 | 12 | 1292 | 4442 | 34951185 |
| Hypotension | 38.32 | 34.81 | 44 | 1260 | 221605 | 34734022 |
| Eosinophilia | 35.51 | 34.81 | 18 | 1286 | 26204 | 34929423 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Anaphylactic shock | 158.32 | 29.12 | 58 | 3131 | 35938 | 79705261 |
| Hypotension | 88.86 | 29.12 | 98 | 3091 | 440219 | 79300980 |
| Maternal exposure during delivery | 80.94 | 29.12 | 17 | 3172 | 1329 | 79739870 |
| Anterior spinal artery syndrome | 79.90 | 29.12 | 12 | 3177 | 130 | 79741069 |
| Eosinophilia | 67.64 | 29.12 | 34 | 3155 | 45311 | 79695888 |
| Anaphylactic reaction | 62.77 | 29.12 | 40 | 3149 | 83703 | 79657496 |
| Metal poisoning | 60.76 | 29.12 | 9 | 3180 | 88 | 79741111 |
| Bradycardia | 60.21 | 29.12 | 47 | 3142 | 135510 | 79605689 |
| Spinal cord injury | 58.91 | 29.12 | 13 | 3176 | 1282 | 79739917 |
| Cardio-respiratory arrest | 53.39 | 29.12 | 40 | 3149 | 108470 | 79632729 |
| Exposure during pregnancy | 49.12 | 29.12 | 37 | 3152 | 101095 | 79640104 |
| Drug abuse | 48.77 | 29.12 | 45 | 3144 | 162646 | 79578553 |
| Mental status changes postoperative | 47.91 | 29.12 | 8 | 3181 | 177 | 79741022 |
| Cardiac arrest | 46.61 | 29.12 | 45 | 3144 | 172051 | 79569148 |
| Confusion postoperative | 46.45 | 29.12 | 8 | 3181 | 214 | 79740985 |
| Drug reaction with eosinophilia and systemic symptoms | 46.42 | 29.12 | 30 | 3159 | 64214 | 79676985 |
| Toxicity to various agents | 45.53 | 29.12 | 69 | 3120 | 421471 | 79319728 |
| Tachycardia | 45.37 | 29.12 | 45 | 3144 | 177723 | 79563476 |
| Rhythm idioventricular | 44.03 | 29.12 | 9 | 3180 | 615 | 79740584 |
| Angle closure glaucoma | 43.50 | 29.12 | 12 | 3177 | 2964 | 79738235 |
| Procedural hypotension | 43.14 | 29.12 | 11 | 3178 | 2012 | 79739187 |
| Rash maculo-papular | 42.52 | 29.12 | 27 | 3162 | 56051 | 79685148 |
| Maternal exposure during pregnancy | 41.35 | 29.12 | 38 | 3151 | 136500 | 79604699 |
| Stress cardiomyopathy | 38.19 | 29.12 | 15 | 3174 | 11151 | 79730048 |
| Haemodynamic instability | 38.08 | 29.12 | 17 | 3172 | 17365 | 79723834 |
| Arteriospasm coronary | 37.73 | 29.12 | 13 | 3176 | 6703 | 79734496 |
| Locked-in syndrome | 36.85 | 29.12 | 8 | 3181 | 731 | 79740468 |
| Ventricular tachycardia | 36.37 | 29.12 | 22 | 3167 | 41913 | 79699286 |
| Embolic stroke | 32.09 | 29.12 | 12 | 3177 | 7814 | 79733385 |
| Airway complication of anaesthesia | 29.29 | 29.12 | 6 | 3183 | 414 | 79740785 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A08AA56 | ALIMENTARY TRACT AND METABOLISM ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS Centrally acting antiobesity products |
| ATC | C01CA26 | CARDIOVASCULAR SYSTEM CARDIAC THERAPY CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES Adrenergic and dopaminergic agents |
| ATC | R01AA03 | RESPIRATORY SYSTEM NASAL PREPARATIONS DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE Sympathomimetics, plain |
| ATC | R01AB05 | RESPIRATORY SYSTEM NASAL PREPARATIONS DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE Sympathomimetics, combinations excl. corticosteroids |
| ATC | R03CA02 | RESPIRATORY SYSTEM DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES ADRENERGICS FOR SYSTEMIC USE Alpha- and beta-adrenoreceptor agonists |
| ATC | S01FB02 | SENSORY ORGANS OPHTHALMOLOGICALS MYDRIATICS AND CYCLOPLEGICS Sympathomimetics excl. antiglaucoma preparations |
| FDA MoA | N0000000209 | Adrenergic alpha-Agonists |
| FDA MoA | N0000000245 | Adrenergic beta-Agonists |
| FDA PE | N0000009456 | Increased Norepinephrine Activity |
| FDA EPC | N0000175552 | alpha-Adrenergic Agonist |
| FDA EPC | N0000175555 | beta-Adrenergic Agonist |
| MeSH PA | D018663 | Adrenergic Agents |
| MeSH PA | D002317 | Cardiovascular Agents |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D000697 | Central Nervous System Stimulants |
| MeSH PA | D018377 | Neurotransmitter Agents |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D013566 | Sympathomimetics |
| MeSH PA | D014662 | Vasoconstrictor Agents |
| CHEBI has role | CHEBI:35524 | sympathomimetic |
| CHEBI has role | CHEBI:35703 | Xenobiotic |
| CHEBI has role | CHEBI:76924 | plant metabolites |
| CHEBI has role | CHEBI:77715 | nasal decongestants |
| CHEBI has role | CHEBI:78298 | environmental contaminants |
| FDA EPC | N0000192563 | Norepinephrine Releasing Agent |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Bronchospasm | indication | 4386001 | |
| Sinus headache | indication | 4969004 | |
| Vasomotor rhinitis | indication | 8229003 | DOID:4730 |
| Bronchitis | indication | 32398004 | DOID:6132 |
| Allergic rhinitis | indication | 61582004 | |
| Nasal discharge | indication | 64531003 | |
| Nasal congestion | indication | 68235000 | |
| Rhinitis | indication | 70076002 | DOID:4483 |
| Sneezing | indication | 76067001 | |
| Common cold | indication | 82272006 | DOID:10459 |
| Headache disorder | indication | 230461009 | |
| Influenza-like symptoms | indication | 315642008 | |
| Seasonal allergic rhinitis | indication | 367498001 | |
| Allergic conjunctivitis | indication | 473460002 | DOID:11204 |
| Intracranial hemorrhage | contraindication | 1386000 | |
| Brain damage | contraindication | 2470005 | |
| Goiter | contraindication | 3716002 | DOID:12176 |
| Ocular hypertension | contraindication | 4210003 | DOID:9282 |
| Gastritis | contraindication | 4556007 | DOID:4029 |
| Tachyarrhythmia | contraindication | 6285003 | |
| Suicidal thoughts | contraindication | 6471006 | |
| Dependent drug abuse | contraindication | 6525002 | |
| Urinary tract obstruction | contraindication | 7163005 | DOID:5200 |
| Alcoholism | contraindication | 7200002 | |
| Alcohol withdrawal delirium | contraindication | 8635005 | |
| Hyperammonemia | contraindication | 9360008 | |
| Peptic ulcer | contraindication | 13200003 | DOID:750 |
| Chronic obstructive lung disease | contraindication | 13645005 | DOID:3083 |
| Asthenia | contraindication | 13791008 | |
| Hepatic encephalopathy | contraindication | 13920009 | DOID:13413 |
| Hyperkalemia | contraindication | 14140009 | |
| Severe chronic ulcerative colitis | contraindication | 14311001 | |
| Constipation | contraindication | 14760008 | DOID:2089 |
| Disorder of autonomic nervous system | contraindication | 15241006 | |
| Chronic disease of respiratory system | contraindication | 17097001 | |
| Mood swings | contraindication | 18963009 | |
| Pulmonary edema | contraindication | 19242006 | DOID:11396 |
| Hashimoto thyroiditis | contraindication | 21983002 | |
| Myocardial infarction | contraindication | 22298006 | DOID:5844 |
| Glaucoma | contraindication | 23986001 | DOID:1686 |
| Inflammatory bowel disease | contraindication | 24526004 | DOID:0050589 |
| Ventricular tachycardia | contraindication | 25569003 | |
| Acute tuberculosis | contraindication | 25629007 | |
| Alcohol intoxication | contraindication | 25702006 | |
| Shock | contraindication | 27942005 | |
| Toxic megacolon | contraindication | 28536002 | DOID:1770 |
| Atony of colon | contraindication | 29479008 | |
| Hypercapnia | contraindication | 29596007 | |
| Dehydration | contraindication | 34095006 | |
| Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
| Depressive disorder | contraindication | 35489007 | |
| Acute hepatitis | contraindication | 37871000 | |
| Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
| Hypovolemic shock | contraindication | 39419009 | |
| Disorder of gallbladder | contraindication | 39621005 | DOID:0060262 |
| Gastrointestinal ulcer | contraindication | 40845000 | |
| Hypothyroidism | contraindication | 40930008 | DOID:1459 |
| Complete trisomy 21 syndrome | contraindication | 41040004 | DOID:14250 |
| Third trimester pregnancy | contraindication | 41587001 | |
| Body fluid retention | contraindication | 43498006 | |
| Conduction disorder of the heart | contraindication | 44808001 | |
| Low blood pressure | contraindication | 45007003 | |
| Achalasia of esophagus | contraindication | 45564002 | DOID:9164 |
| Pregnancy-induced hypertension | contraindication | 48194001 | |
| Chronic heart failure | contraindication | 48447003 | |
| Bradycardia | contraindication | 48867003 | |
| Disorder of cardiovascular system | contraindication | 49601007 | DOID:1287 |
| Acidosis | contraindication | 51387008 | |
| Gastrointestinal perforation | contraindication | 51875005 | |
| Coronary arteriosclerosis | contraindication | 53741008 | DOID:3393 |
| Paralytic ileus | contraindication | 55525008 | DOID:8442 |
| Heart disease | contraindication | 56265001 | DOID:114 |
| Peptic reflux disease | contraindication | 57643001 | |
| Multiple organ failure | contraindication | 57653000 | |
| Acute nephropathy | contraindication | 58574008 | |
| Metabolic acidosis | contraindication | 59455009 | |
| Hepatic failure | contraindication | 59927004 | |
| Ulcerative colitis | contraindication | 64766004 | DOID:8577 |
| Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
| Poisoning by phenobarbital | contraindication | 64921004 | |
| Arterial thrombosis | contraindication | 65198009 | |
| Drug AND/OR toxin-induced diarrhea | contraindication | 65979008 | |
| Substance abuse | contraindication | 66214007 | |
| Benign intracranial hypertension | contraindication | 68267002 | DOID:11459 |
| Psychotic disorder | contraindication | 69322001 | |
| Poisoning by acetaminophen | contraindication | 70273001 | |
| Abnormal vasomotor function | contraindication | 70670009 | |
| Arteriosclerotic vascular disease | contraindication | 72092001 | |
| Hepatic coma | contraindication | 72836002 | DOID:12550 |
| Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
| Sleep apnea | contraindication | 73430006 | DOID:0050847 |
| Gastrointestinal hemorrhage | contraindication | 74474003 | |
| Urethral stricture | contraindication | 76618002 | |
| Spastic paralysis | contraindication | 78403003 | |
| Disturbance of salivary secretion | contraindication | 78948009 | |
| Decreased respiratory function | contraindication | 80954004 | |
| Injury of head | contraindication | 82271004 | |
| Chronic idiopathic constipation | contraindication | 82934008 | |
| Oliguria | contraindication | 83128009 | |
| Cor pulmonale | contraindication | 83291003 | DOID:8515 |
| Hiatal hernia | contraindication | 84089009 | DOID:12642 |
| Open-angle glaucoma | contraindication | 84494001 | DOID:1067 |
| Epilepsy | contraindication | 84757009 | DOID:1826 |
| Pulmonary emphysema | contraindication | 87433001 | |
| Kidney disease | contraindication | 90708001 | DOID:557 |
| Thyrotoxicosis | contraindication | 90739004 | DOID:7997 |
| Myasthenia gravis | contraindication | 91637004 | DOID:437 |
| Dermatitis herpetiformis | contraindication | 111196000 | DOID:8505 |
| Acute abdominal pain | contraindication | 116290004 | |
| Procedure on urinary system | contraindication | 118677009 | |
| Gastrointestinal obstruction | contraindication | 126765001 | |
| Neoplasm of brain | contraindication | 126952004 | DOID:1319 |
| Seizure disorder | contraindication | 128613002 | |
| Autonomic dysreflexia | contraindication | 129618003 | |
| Bleeding | contraindication | 131148009 | |
| Liver function tests abnormal | contraindication | 166603001 | |
| Cystic fibrosis | contraindication | 190905008 | DOID:1485 |
| Drug-induced psychosis | contraindication | 191483003 | DOID:1742 |
| Angina pectoris | contraindication | 194828000 | |
| Partial atrioventricular block | contraindication | 195039008 | |
| Acute pancreatitis | contraindication | 197456007 | DOID:2913 |
| Impaired renal function disorder | contraindication | 197663003 | |
| Cerebrovascular accident | contraindication | 230690007 | |
| Coronary artery bypass graft | contraindication | 232717009 | |
| Myocardial dysfunction | contraindication | 233928007 | |
| Gastroesophageal reflux disease | contraindication | 235595009 | DOID:8534 |
| Disease of liver | contraindication | 235856003 | DOID:409 |
| Hyporeninemic hypoaldosteronism | contraindication | 236464008 | |
| Bladder outflow obstruction | contraindication | 236645006 | |
| Morbid obesity | contraindication | 238136002 | DOID:11981 |
| Sepsis syndrome | contraindication | 238150007 | |
| Hypocomplementemic urticarial vasculitis | contraindication | 239945009 | |
| Rhabdomyolysis | contraindication | 240131006 | |
| Pyloric obstruction | contraindication | 244815007 | |
| Esophageal dysmotility | contraindication | 266434009 | DOID:9192 |
| Benign prostatic hyperplasia | contraindication | 266569009 | |
| Dyspnea | contraindication | 267036007 | |
| Edema | contraindication | 267038008 | |
| Retention of urine | contraindication | 267064002 | |
| Anemia | contraindication | 271737000 | DOID:2355 |
| Continuous fever | contraindication | 271751000 | |
| Drowsy | contraindication | 271782001 | |
| Exacerbation of asthma | contraindication | 281239006 | |
| Pregnancy, function | contraindication | 289908002 | |
| Lesion of brain | contraindication | 301766008 | |
| Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
| Neutropenic disorder | contraindication | 303011007 | DOID:1227 |
| Thromboembolic disorder | contraindication | 371039008 | |
| Coma | contraindication | 371632003 | |
| Primary adrenocortical insufficiency | contraindication | 373662000 | |
| Smoking cessation assistance | contraindication | 384742004 | |
| Operation on gastrointestinal tract | contraindication | 386621005 | |
| Hypoxia | contraindication | 389086002 | |
| Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
| Cardiovascular event risk | contraindication | 395112001 | |
| Pseudomembranous enterocolitis | contraindication | 397683000 | |
| Gastric ulcer | contraindication | 397825006 | DOID:10808 |
| Breastfeeding (mother) | contraindication | 413712001 | |
| Chronic lung disease | contraindication | 413839001 | |
| Chronic myocardial ischemia | contraindication | 413844008 | DOID:3393 |
| Disorder of coronary artery | contraindication | 414024009 | |
| Myocardial ischemia | contraindication | 414795007 | DOID:3393 |
| Traumatic injury | contraindication | 417746004 | |
| Central nervous system depression | contraindication | 418072004 | |
| Porphyria | contraindication | 418470004 | |
| Ultrarapid metabolizer due to cytochrome p450 CYP2D6 variant | contraindication | 422681000 | |
| Fever greater than 100.4 Fahrenheit | contraindication | 426000000 | |
| Dysfunction of sphincter of Oddi | contraindication | 430887001 | |
| Hypertensive urgency | contraindication | 443482000 | |
| Smokes tobacco daily | contraindication | 449868002 | |
| Acute exacerbation of asthma | contraindication | 708038006 | |
| Acute Thromboembolic Stroke | contraindication | ||
| Severe Hypoxemia | contraindication | ||
| Theophylline Toxicity | contraindication |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.22 | Basic |
Orange Book patent data (new drug applications)
| Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
|---|---|---|---|---|---|---|---|---|---|---|
| 25MG/5ML (5MG/ML) | EMERPHED | NEXUS | N213407 | Feb. 28, 2023 | RX | SOLUTION | INTRAVENOUS | 11571398 | May 16, 2040 | USE OF EPHEDRINE SULFATE FOR TREATING HYPOTENSION |
| 50MG/10ML (5MG/ML) | EMERPHED | NEXUS | N213407 | April 17, 2020 | RX | SOLUTION | INTRAVENOUS | 11090278 | May 16, 2040 | USE OF EPHEDRINE SULFATE FOR TREATING HYPOTENSION |
| 50MG/10ML (5MG/ML) | EMERPHED | NEXUS | N213407 | April 17, 2020 | RX | SOLUTION | INTRAVENOUS | 11241400 | May 16, 2040 | USE OF EPHEDRINE SULFATE FOR TREATING HYPOTENSION |
| 50MG/10ML (5MG/ML) | EMERPHED | NEXUS | N213407 | April 17, 2020 | RX | SOLUTION | INTRAVENOUS | 11478436 | May 16, 2040 | USE OF EPHEDRINE SULFATE FOR TREATING HYPOTENSION |
| 50MG/10ML (5MG/ML) | EMERPHED | NEXUS | N213407 | April 17, 2020 | RX | SOLUTION | INTRAVENOUS | 11571398 | May 16, 2040 | USE OF EPHEDRINE SULFATE FOR TREATING HYPOTENSION |
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Beta-2 adrenergic receptor | GPCR | AGONIST | Ki | 5.60 | IUPHAR | IUPHAR |
External reference:
| ID | Source |
|---|---|
| 4017462 | VUID |
| N0000179480 | NUI |
| D00124 | KEGG_DRUG |
| 134-72-5 | SECONDARY_CAS_RN |
| 50-98-6 | SECONDARY_CAS_RN |
| 4017462 | VANDF |
| 4018445 | VANDF |
| 4019279 | VANDF |
| C0014479 | UMLSCUI |
| CHEBI:15407 | CHEBI |
| CHEMBL211456 | ChEMBL_ID |
| DB01364 | DRUGBANK_ID |
| CHEMBL1523964 | ChEMBL_ID |
| CHEMBL526872 | ChEMBL_ID |
| CHEMBL2146102 | ChEMBL_ID |
| D004809 | MESH_DESCRIPTOR_UI |
| 9294 | PUBCHEM_CID |
| 556 | IUPHAR_LIGAND_ID |
| GN83C131XS | UNII |
| 3966 | RXNORM |
| 3438 | MMSL |
| 4660 | MMSL |
| 4661 | MMSL |
| 6510 | MMSL |
| 71901 | MMSL |
| d00700 | MMSL |
| 001820 | NDDF |
| 001821 | NDDF |
| 001822 | NDDF |
| 387327006 | SNOMEDCT_US |
| 387358007 | SNOMEDCT_US |
| 65026000 | SNOMEDCT_US |
| 76525000 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Bronchial Asthma Relief | HUMAN OTC DRUG LABEL | 2 | 0363-2529 | TABLET | 12.50 mg | ORAL | OTC monograph final | 15 sections |
| Ephedrine Sulfate | HUMAN OTC DRUG LABEL | 1 | 0363-5789 | TABLET, FILM COATED | 25 mg | ORAL | OTC monograph final | 18 sections |
| Ephedrine Hydrochloride | HUMAN OTC DRUG LABEL | 1 | 0363-9812 | TABLET | 12.50 mg | ORAL | OTC monograph final | 18 sections |
| PRIMATENE | HUMAN OTC DRUG LABEL | 2 | 0573-2952 | TABLET | 12.50 mg | ORAL | OTC monograph final | 17 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6238 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 25 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-3269 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-3269 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-3269 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-3269 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 14789-014 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | unapproved drug other | 17 sections |
| Emerphed | HUMAN PRESCRIPTION DRUG LABEL | 1 | 14789-250 | INJECTION | 5 mg | INTRAVENOUS | NDA | 25 sections |
| Emerphed | HUMAN PRESCRIPTION DRUG LABEL | 1 | 14789-250 | INJECTION | 5 mg | INTRAVENOUS | NDA | 25 sections |
| Emerphed | HUMAN PRESCRIPTION DRUG LABEL | 1 | 14789-251 | INJECTION | 5 mg | INTRAVENOUS | NDA | 26 sections |
| Emerphed | HUMAN PRESCRIPTION DRUG LABEL | 1 | 14789-252 | INJECTION | 5 mg | INTRAVENOUS | NDA | 26 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16714-037 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16714-037 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17478-415 | INJECTION | 50 mg | INTRAVENOUS | NDA | 25 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17478-415 | INJECTION | 50 mg | INTRAVENOUS | NDA | 25 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17478-515 | INJECTION | 50 mg | INTRAMUSCULAR | unapproved drug other | 17 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17478-517 | INJECTION | 50 mg | INTRAVENOUS | NDA | 25 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17478-517 | INJECTION | 50 mg | INTRAVENOUS | NDA | 25 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17478-955 | INJECTION | 50 mg | INTRAVENOUS | NDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 17478-955 | INJECTION | 50 mg | INTRAVENOUS | NDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 25021-836 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 25 sections |
| REZIPRES | HUMAN PRESCRIPTION DRUG LABEL | 1 | 39822-1410 | INJECTION, SOLUTION | 4.70 mg | INTRAVENOUS | NDA | 25 sections |
| Corphedra | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-196 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | NDA | 24 sections |
| Corphedra | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-196 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | NDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-216 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | NDA | 24 sections |
| Ephedrine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-216 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | NDA | 24 sections |
| Corphedra | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-233 | INJECTION, SOLUTION | 500 mg | INTRAVENOUS | NDA | 24 sections |