Drug results: 68
| titanium dioxide | used medically as protectant against externally caused irritation & sunlight; high concentrations of dust may cause irritation to respiratory tract; RN given refers to titanium oxide (TiO2); structure |
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| pentobarbital | A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236) |
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| amobarbital | A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565) |
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| hexobarbital | A barbiturate that is effective as a hypnotic and sedative. |
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| eszopiclone | A pyridine, pyrazine, and piperazine derivative that is used as a HYPNOTIC AND SEDATIVE in the treatment of INSOMNIA. |
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| zaleplon | an azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; a hypnotic with less marked effect on psychomotor functions compared to lorazepam |
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| barbital | A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice for central nervous system depression. |
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| buthalital |
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| etallobarbital |
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| phetharbital |
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| eterobarb |
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| cyclopentobarbital |
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| vinbarbital |
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| heptobarbital |
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| aprobarbital |
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| allobarbital |
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| butalbital | management of butalbital withdrawal can be simplified by using a phenobarbital-loading protocol; RN given refers to parent cpd |
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| bucolome |
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| reposal |
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| eltanolone | A pregnane found in the urine of pregnant women and sows. It has anesthetic, hypnotic, and sedative properties. |
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| thialbarbital |
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| estazolam | A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than DIAZEPAM or NITRAZEPAM. |
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| secbutabarbital | Butabarbital (a synonym for Secbutabarbital) should be distinguished from Butobarbital |
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| metharbital |
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| nitrazepam | A benzodiazepine derivative used as an anticonvulsant and hypnotic. |
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| methohexital | An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia. |
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| butobarbital | Butobarbital should be distinguished from Butabarbital (a synonym for Secbutabarbital) |
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| etomidate | Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic. |
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| methylphenobarbital | A barbiturate that is metabolized to PHENOBARBITAL. It has been used for similar purposes, especially in EPILEPSY, but there is no evidence mephobarbital offers any advantage over PHENOBARBITAL. |
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| thiamylal | A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state. (From Martindale, The Extra Pharmacopoeia, 30th ed, p919) |
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| chloral hydrate | A hypnotic and sedative used in the treatment of INSOMNIA. |
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| ethinamate | short duration hypnotic with fast onset & relatively low toxicity; may cause dependence; minor descriptor (76-85); on-line & Index Medicus search CARBAMATES (76-85) |
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| methapyrilene | Histamine H1 antagonist with sedative action used as a hypnotic and in allergies. |
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| glutethimide | A hypnotic and sedative. Its use has been largely superseded by other drugs. |
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| bromisoval | A sedative and mild hypnotic with potentially toxic effects. |
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| methaqualone | A quinazoline derivative with hypnotic and sedative properties. It has been withdrawn from the market in many countries because of problems with abuse. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604) |
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| phenobarbital | A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations. |
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| secobarbital | A barbiturate that is used as a sedative. Secobarbital is reported to have no anti-anxiety activity. |
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| flurazepam | A benzodiazepine derivative used mainly as a hypnotic. |
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| diphenhydramine | A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. |
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| doxylamine | Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM. |
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| proxibarbal |
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| cyclobarbital |
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| propallylonal |
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| methitural |
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| vinylbital |
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| brallobarbital |
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| difebarbamate |
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| febarbamate |
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| talbutal |
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| carbubarb |
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| heptabarb |
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| ethchlorvynol | A sedative and hypnotic that has been used in the short-term management of INSOMNIA. Its use has been superseded by other drugs. |
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| alprazolam | A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238) |
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| lorazepam | A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent. |
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| meprobamate | A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) |
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| thiopental | A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. |
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| mepyramine | A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies. |
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| zopiclone | S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007 |
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| thalidomide | A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action. |
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| barbexaclone | ||
| midazolam | A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH. |
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| narcobarbital |
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| pimeclone |
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| tetrabarbital |
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| enallylpropymal |
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| nealbarbital |
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| paraldehyde | A hypnotic and sedative with anticonvulsant effects. However, because of the hazards associated with its administration, its tendency to react with plastic, and the risks associated with its deterioration, it has largely been superseded by other agents. It is still occasionally used to control status epilepticus resistant to conventional treatment. (From Martindale, The Extra Pharmacopoeia, 30th ed, p608-9) |
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