Stem definition | Drug id | CAS RN |
---|---|---|
quinoline derivatives | 1395 | 118-42-3 |
Dose | Unit | Route |
---|---|---|
0.52 | g | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 200 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 27 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 29.77 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 74 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 700 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 11 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.57 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 850 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
April 18, 1955 | FDA | SANOFI AVENTIS US |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug ineffective | 6984.25 | 11.14 | 17339 | 361456 | 801994 | 49424335 |
Drug intolerance | 4788.28 | 11.14 | 6967 | 371828 | 212137 | 50014192 |
Rheumatoid arthritis | 3554.86 | 11.14 | 5824 | 372971 | 196726 | 50029603 |
Contraindicated product administered | 3320.82 | 11.14 | 4787 | 374008 | 144171 | 50082158 |
Joint swelling | 3085.59 | 11.14 | 6101 | 372694 | 239185 | 49987144 |
Synovitis | 2878.98 | 11.14 | 4062 | 374733 | 119803 | 50106526 |
Treatment failure | 2710.49 | 11.14 | 4175 | 374620 | 133462 | 50092867 |
Therapeutic product effect decreased | 1988.28 | 11.14 | 3612 | 375183 | 132438 | 50093891 |
Systemic lupus erythematosus | 1956.45 | 11.14 | 3655 | 375140 | 136967 | 50089362 |
Arthropathy | 1847.60 | 11.14 | 3816 | 374979 | 154090 | 50072239 |
Pemphigus | 1619.33 | 11.14 | 3082 | 375713 | 117084 | 50109245 |
Abdominal discomfort | 1488.91 | 11.14 | 4451 | 374344 | 227190 | 49999139 |
Hand deformity | 1294.28 | 11.14 | 2525 | 376270 | 97674 | 50128655 |
Glossodynia | 1275.97 | 11.14 | 2729 | 376066 | 112840 | 50113489 |
Death | 1258.27 | 11.14 | 434 | 378361 | 324945 | 49901384 |
Pain | 1246.91 | 11.14 | 7985 | 370810 | 570918 | 49655411 |
Alopecia | 1234.30 | 11.14 | 4333 | 374462 | 240714 | 49985615 |
Swelling | 1216.99 | 11.14 | 3782 | 375013 | 197090 | 50029239 |
Arthralgia | 1101.34 | 11.14 | 6301 | 372494 | 432401 | 49793928 |
C-reactive protein abnormal | 955.49 | 11.14 | 1109 | 377686 | 26700 | 50199629 |
Rheumatoid factor positive | 880.44 | 11.14 | 1441 | 377354 | 48418 | 50177911 |
Hepatic enzyme increased | 836.78 | 11.14 | 2593 | 376202 | 134787 | 50091542 |
Anti-cyclic citrullinated peptide antibody positive | 827.36 | 11.14 | 1709 | 377086 | 68878 | 50157451 |
Therapeutic product effect incomplete | 816.29 | 11.14 | 1987 | 376808 | 89528 | 50136801 |
Musculoskeletal stiffness | 804.76 | 11.14 | 2449 | 376346 | 126032 | 50100297 |
Off label use | 773.72 | 11.14 | 6125 | 372670 | 468301 | 49758028 |
Red blood cell sedimentation rate abnormal | 762.06 | 11.14 | 766 | 378029 | 15577 | 50210752 |
Acute kidney injury | 760.02 | 11.14 | 379 | 378416 | 227679 | 49998650 |
Peripheral swelling | 726.32 | 11.14 | 3259 | 375536 | 202677 | 50023652 |
Wound | 720.79 | 11.14 | 2078 | 376717 | 103716 | 50122613 |
Completed suicide | 689.98 | 11.14 | 87 | 378708 | 131802 | 50094527 |
Condition aggravated | 646.83 | 11.14 | 4116 | 374679 | 292942 | 49933387 |
Pericarditis | 641.17 | 11.14 | 1651 | 377144 | 77038 | 50149291 |
Anaemia | 595.55 | 11.14 | 607 | 378188 | 251849 | 49974480 |
Rash | 591.37 | 11.14 | 5419 | 373376 | 432052 | 49794277 |
Constipation | 591.36 | 11.14 | 327 | 378468 | 185381 | 50040948 |
Discomfort | 562.60 | 11.14 | 1938 | 376857 | 106442 | 50119887 |
Hypersensitivity | 558.03 | 11.14 | 3122 | 375673 | 212039 | 50014290 |
Drug hypersensitivity | 553.42 | 11.14 | 3490 | 375305 | 247520 | 49978809 |
Red blood cell sedimentation rate increased | 546.14 | 11.14 | 870 | 377925 | 28546 | 50197783 |
Dehydration | 537.46 | 11.14 | 234 | 378561 | 152215 | 50074114 |
Loss of personal independence in daily activities | 535.16 | 11.14 | 1435 | 377360 | 68615 | 50157714 |
Hypotension | 517.79 | 11.14 | 600 | 378195 | 234869 | 49991460 |
Product use issue | 494.84 | 11.14 | 2323 | 376472 | 147152 | 50079177 |
C-reactive protein increased | 487.01 | 11.14 | 1341 | 377454 | 65133 | 50161196 |
Gastrointestinal disorder | 480.54 | 11.14 | 1678 | 377117 | 92778 | 50133551 |
Maternal exposure during pregnancy | 462.53 | 11.14 | 2390 | 376405 | 157388 | 50068941 |
Infusion related reaction | 456.48 | 11.14 | 2486 | 376309 | 167071 | 50059258 |
Febrile neutropenia | 455.19 | 11.14 | 89 | 378706 | 97578 | 50128751 |
Infection | 449.70 | 11.14 | 2512 | 376283 | 170442 | 50055887 |
Hyponatraemia | 449.34 | 11.14 | 87 | 378708 | 96052 | 50130277 |
Malignant neoplasm progression | 435.43 | 11.14 | 17 | 378778 | 68107 | 50158222 |
Tremor | 415.11 | 11.14 | 170 | 378625 | 114733 | 50111596 |
Muscle injury | 411.81 | 11.14 | 879 | 377916 | 36232 | 50190097 |
Seizure | 402.75 | 11.14 | 189 | 378606 | 117685 | 50108644 |
Folliculitis | 396.63 | 11.14 | 895 | 377900 | 38330 | 50187999 |
Ill-defined disorder | 377.14 | 11.14 | 1079 | 377716 | 53575 | 50172754 |
Lower respiratory tract infection | 375.83 | 11.14 | 1560 | 377235 | 93641 | 50132688 |
Helicobacter infection | 371.28 | 11.14 | 1010 | 377785 | 48692 | 50177637 |
Duodenal ulcer perforation | 361.03 | 11.14 | 947 | 377848 | 44664 | 50181665 |
Toxicity to various agents | 360.10 | 11.14 | 650 | 378145 | 211849 | 50014480 |
Dyspnoea | 359.83 | 11.14 | 2513 | 376282 | 545095 | 49681234 |
Retinal toxicity | 358.34 | 11.14 | 176 | 378619 | 1012 | 50225317 |
Irritable bowel syndrome | 352.44 | 11.14 | 1013 | 377782 | 50428 | 50175901 |
Somnolence | 345.75 | 11.14 | 390 | 378405 | 154595 | 50071734 |
Anxiety | 339.44 | 11.14 | 502 | 378293 | 177104 | 50049225 |
Drug interaction | 326.34 | 11.14 | 624 | 378171 | 198997 | 50027332 |
Impaired healing | 323.52 | 11.14 | 1203 | 377592 | 68583 | 50157746 |
Dizziness | 318.41 | 11.14 | 1422 | 377373 | 344947 | 49881382 |
Knee arthroplasty | 316.75 | 11.14 | 776 | 378019 | 35070 | 50191259 |
Drug abuse | 316.44 | 11.14 | 38 | 378757 | 59808 | 50166521 |
Atrial fibrillation | 308.23 | 11.14 | 190 | 378605 | 101555 | 50124774 |
Psoriatic arthropathy | 307.62 | 11.14 | 911 | 377884 | 46121 | 50180208 |
Sleep disorder due to general medical condition, insomnia type | 297.47 | 11.14 | 699 | 378096 | 30748 | 50195581 |
Bradycardia | 297.44 | 11.14 | 60 | 378735 | 64366 | 50161963 |
Pulmonary embolism | 293.03 | 11.14 | 201 | 378594 | 101503 | 50124826 |
Rheumatoid nodule | 292.39 | 11.14 | 416 | 378379 | 12319 | 50214010 |
Overdose | 291.47 | 11.14 | 194 | 378601 | 99533 | 50126796 |
Renal failure | 289.98 | 11.14 | 224 | 378571 | 106409 | 50119920 |
Product dose omission issue | 288.95 | 11.14 | 588 | 378207 | 183250 | 50043079 |
Fall | 284.87 | 11.14 | 1414 | 377381 | 333518 | 49892811 |
Blood iron abnormal | 284.31 | 11.14 | 220 | 378575 | 3106 | 50223223 |
Neutropenia | 282.88 | 11.14 | 418 | 378377 | 147547 | 50078782 |
Thrombocytopenia | 281.74 | 11.14 | 324 | 378471 | 127349 | 50098980 |
Tachycardia | 272.00 | 11.14 | 209 | 378586 | 99554 | 50126775 |
Depressed level of consciousness | 265.01 | 11.14 | 37 | 378758 | 51916 | 50174413 |
Gastrointestinal haemorrhage | 260.68 | 11.14 | 111 | 378684 | 73210 | 50153119 |
Inflammation | 259.52 | 11.14 | 976 | 377819 | 55936 | 50170393 |
Multiple sclerosis relapse | 257.71 | 11.14 | 16 | 378779 | 42948 | 50183381 |
Impaired work ability | 249.79 | 11.14 | 401 | 378394 | 13239 | 50213090 |
Musculoskeletal disorder | 249.26 | 11.14 | 458 | 378337 | 16891 | 50209438 |
Coma | 248.36 | 11.14 | 60 | 378735 | 56819 | 50169510 |
Mobility decreased | 244.38 | 11.14 | 1215 | 377580 | 78733 | 50147596 |
Hip arthroplasty | 243.02 | 11.14 | 634 | 378161 | 29795 | 50196534 |
Cardio-respiratory arrest | 240.97 | 11.14 | 54 | 378741 | 53838 | 50172491 |
Balance disorder | 238.25 | 11.14 | 115 | 378680 | 70475 | 50155854 |
White blood cell count decreased | 237.76 | 11.14 | 315 | 378480 | 116407 | 50109922 |
Arthritis | 237.39 | 11.14 | 1278 | 377517 | 85443 | 50140886 |
Platelet count decreased | 237.30 | 11.14 | 242 | 378553 | 100484 | 50125845 |
Blister | 234.63 | 11.14 | 1260 | 377535 | 84158 | 50142171 |
Hyperkalaemia | 234.42 | 11.14 | 39 | 378756 | 48050 | 50178279 |
Oedema peripheral | 232.53 | 11.14 | 524 | 378271 | 157437 | 50068892 |
Retinopathy | 230.97 | 11.14 | 179 | 378616 | 2533 | 50223796 |
Disease progression | 228.49 | 11.14 | 228 | 378567 | 95638 | 50130691 |
Sinusitis | 226.21 | 11.14 | 2107 | 376688 | 168451 | 50057878 |
Agitation | 224.09 | 11.14 | 61 | 378734 | 53323 | 50173006 |
Abdominal pain | 223.35 | 11.14 | 959 | 377836 | 235269 | 49991060 |
Cerebrovascular accident | 220.18 | 11.14 | 230 | 378565 | 94450 | 50131879 |
Urinary tract infection | 220.11 | 11.14 | 896 | 377899 | 223124 | 50003205 |
Neutrophil count decreased | 216.37 | 11.14 | 41 | 378754 | 45985 | 50180344 |
Muscle spasms | 215.22 | 11.14 | 381 | 378414 | 125172 | 50101157 |
Decreased appetite | 213.20 | 11.14 | 779 | 378016 | 200144 | 50026185 |
Cardiac arrest | 212.21 | 11.14 | 188 | 378607 | 83463 | 50142866 |
Bone erosion | 203.72 | 11.14 | 336 | 378459 | 11351 | 50214978 |
Pulmonary fibrosis | 202.19 | 11.14 | 516 | 378279 | 23921 | 50202408 |
Sepsis | 199.66 | 11.14 | 436 | 378359 | 132489 | 50093840 |
Diarrhoea | 199.41 | 11.14 | 3154 | 375641 | 585322 | 49641007 |
Cognitive disorder | 197.69 | 11.14 | 44 | 378751 | 44079 | 50182250 |
Haemoglobin decreased | 197.15 | 11.14 | 410 | 378385 | 126806 | 50099523 |
Osteoarthritis | 195.21 | 11.14 | 1022 | 377773 | 67584 | 50158745 |
Asthenia | 194.90 | 11.14 | 1493 | 377302 | 317549 | 49908780 |
Intentional overdose | 194.48 | 11.14 | 113 | 378682 | 62391 | 50163938 |
Suicide attempt | 194.23 | 11.14 | 72 | 378723 | 51660 | 50174669 |
Syncope | 190.97 | 11.14 | 297 | 378498 | 102705 | 50123624 |
Hallucination | 189.03 | 11.14 | 57 | 378738 | 46600 | 50179729 |
Blood glucose increased | 187.38 | 11.14 | 155 | 378640 | 71169 | 50155160 |
Grip strength decreased | 184.33 | 11.14 | 328 | 378467 | 11793 | 50214536 |
Neoplasm progression | 183.86 | 11.14 | 8 | 378787 | 29149 | 50197180 |
Hyperhidrosis | 182.43 | 11.14 | 241 | 378554 | 89185 | 50137144 |
Disability | 181.95 | 11.14 | 336 | 378459 | 12439 | 50213890 |
Rhabdomyolysis | 180.84 | 11.14 | 36 | 378759 | 38991 | 50187338 |
Epistaxis | 179.41 | 11.14 | 130 | 378665 | 63824 | 50162505 |
Lactic acidosis | 179.25 | 11.14 | 20 | 378775 | 33335 | 50192994 |
Joint range of motion decreased | 177.79 | 11.14 | 414 | 378381 | 18098 | 50208231 |
Cardiac failure congestive | 177.72 | 11.14 | 222 | 378573 | 84160 | 50142169 |
Respiratory failure | 177.69 | 11.14 | 254 | 378541 | 90927 | 50135402 |
Cardiac failure | 175.34 | 11.14 | 186 | 378609 | 75854 | 50150475 |
Metabolic acidosis | 173.37 | 11.14 | 39 | 378756 | 38786 | 50187543 |
Granuloma skin | 168.70 | 11.14 | 213 | 378582 | 5605 | 50220724 |
Blood parathyroid hormone decreased | 168.66 | 11.14 | 236 | 378559 | 6878 | 50219451 |
Sedation | 167.97 | 11.14 | 17 | 378778 | 30593 | 50195736 |
Dysphagia | 167.41 | 11.14 | 200 | 378595 | 77318 | 50149011 |
Device expulsion | 166.28 | 11.14 | 13 | 378782 | 28809 | 50197520 |
Panniculitis | 164.00 | 11.14 | 256 | 378539 | 8247 | 50218082 |
International normalised ratio increased | 163.79 | 11.14 | 59 | 378736 | 43093 | 50183236 |
Fibromyalgia | 163.41 | 11.14 | 719 | 378076 | 44259 | 50182070 |
Musculoskeletal pain | 161.83 | 11.14 | 1009 | 377786 | 71168 | 50155161 |
Chest pain | 161.05 | 11.14 | 728 | 378067 | 176154 | 50050175 |
Tenosynovitis | 160.79 | 11.14 | 286 | 378509 | 10279 | 50216050 |
Maculopathy | 158.85 | 11.14 | 126 | 378669 | 1848 | 50224481 |
Deep vein thrombosis | 158.44 | 11.14 | 189 | 378606 | 73115 | 50153214 |
Deafness transitory | 156.14 | 11.14 | 120 | 378675 | 1676 | 50224653 |
Deformity | 154.46 | 11.14 | 240 | 378555 | 7700 | 50218629 |
Wrong technique in product usage process | 154.19 | 11.14 | 114 | 378681 | 55396 | 50170933 |
Depression | 153.51 | 11.14 | 676 | 378119 | 164747 | 50061582 |
Disturbance in attention | 152.64 | 11.14 | 25 | 378770 | 31161 | 50195168 |
Intentional product use issue | 151.58 | 11.14 | 1041 | 377754 | 75877 | 50150452 |
Paraesthesia | 149.78 | 11.14 | 434 | 378361 | 119809 | 50106520 |
Serotonin syndrome | 148.82 | 11.14 | 9 | 378786 | 24704 | 50201625 |
Drug tolerance decreased | 145.93 | 11.14 | 253 | 378542 | 8907 | 50217422 |
Feeling abnormal | 144.88 | 11.14 | 469 | 378326 | 125023 | 50101306 |
Respiratory arrest | 144.79 | 11.14 | 25 | 378770 | 29984 | 50196345 |
Hypoglycaemia | 143.77 | 11.14 | 114 | 378681 | 53467 | 50172862 |
Pneumonia | 143.77 | 11.14 | 1982 | 376813 | 376419 | 49849910 |
Rheumatic fever | 143.54 | 11.14 | 360 | 378435 | 16507 | 50209822 |
Shoulder arthroplasty | 143.35 | 11.14 | 152 | 378643 | 3296 | 50223033 |
Plasma cell myeloma | 142.83 | 11.14 | 30 | 378765 | 31292 | 50195037 |
Therapeutic response decreased | 140.87 | 11.14 | 713 | 378082 | 46518 | 50179811 |
Swollen joint count increased | 139.97 | 11.14 | 330 | 378465 | 14543 | 50211786 |
Bone pain | 139.12 | 11.14 | 91 | 378704 | 47138 | 50179191 |
Myalgia | 136.41 | 11.14 | 475 | 378320 | 123844 | 50102485 |
Hypoxia | 135.63 | 11.14 | 110 | 378685 | 51013 | 50175316 |
Blood pressure decreased | 135.45 | 11.14 | 131 | 378664 | 55778 | 50170551 |
Neuropathy peripheral | 135.06 | 11.14 | 330 | 378465 | 96427 | 50129902 |
Pleural effusion | 134.34 | 11.14 | 253 | 378542 | 81201 | 50145128 |
Vomiting | 133.97 | 11.14 | 2537 | 376258 | 458221 | 49768108 |
Stomatitis | 133.21 | 11.14 | 1250 | 377545 | 100094 | 50126235 |
Nasopharyngitis | 132.90 | 11.14 | 2105 | 376690 | 190822 | 50035507 |
Lupus nephritis | 131.66 | 11.14 | 122 | 378673 | 2233 | 50224096 |
Chest discomfort | 130.40 | 11.14 | 315 | 378480 | 92407 | 50133922 |
Joint effusion | 129.22 | 11.14 | 295 | 378500 | 12726 | 50213603 |
Dyskinesia | 128.46 | 11.14 | 26 | 378769 | 27835 | 50198494 |
Fluid retention | 127.03 | 11.14 | 115 | 378680 | 50534 | 50175795 |
Sopor | 126.86 | 11.14 | 5 | 378790 | 19874 | 50206455 |
Pancytopenia | 126.64 | 11.14 | 275 | 378520 | 83755 | 50142574 |
Finger deformity | 126.60 | 11.14 | 183 | 378612 | 5499 | 50220830 |
Encephalopathy | 126.40 | 11.14 | 47 | 378748 | 33664 | 50192665 |
Hyperglycaemia | 126.38 | 11.14 | 57 | 378738 | 36348 | 50189981 |
Musculoskeletal deformity | 125.86 | 11.14 | 83 | 378712 | 895 | 50225434 |
Pneumonia aspiration | 125.36 | 11.14 | 38 | 378757 | 30966 | 50195363 |
Drug withdrawal syndrome | 125.26 | 11.14 | 19 | 378776 | 25062 | 50201267 |
Joint stiffness | 124.47 | 11.14 | 503 | 378292 | 29805 | 50196524 |
Disorientation | 122.49 | 11.14 | 56 | 378739 | 35428 | 50190901 |
Liver function test increased | 122.42 | 11.14 | 446 | 378349 | 25160 | 50201169 |
Palmar-plantar erythrodysaesthesia syndrome | 121.99 | 11.14 | 7 | 378788 | 20091 | 50206238 |
Melaena | 121.94 | 11.14 | 26 | 378769 | 26838 | 50199491 |
Unresponsive to stimuli | 121.11 | 11.14 | 39 | 378756 | 30570 | 50195759 |
Joint destruction | 120.97 | 11.14 | 148 | 378647 | 3768 | 50222561 |
Pulmonary oedema | 120.50 | 11.14 | 113 | 378682 | 48825 | 50177504 |
Blood cholesterol increased | 119.47 | 11.14 | 765 | 378030 | 54450 | 50171879 |
Hepatic failure | 119.39 | 11.14 | 46 | 378749 | 32237 | 50194092 |
Product quality issue | 119.15 | 11.14 | 41 | 378754 | 30817 | 50195512 |
Polyarthritis | 118.60 | 11.14 | 213 | 378582 | 7714 | 50218615 |
Blood bilirubin increased | 117.91 | 11.14 | 46 | 378749 | 31992 | 50194337 |
X-ray abnormal | 117.58 | 11.14 | 121 | 378674 | 2531 | 50223798 |
Fatigue | 117.53 | 11.14 | 6442 | 372353 | 701159 | 49525170 |
Fine motor skill dysfunction | 117.04 | 11.14 | 149 | 378646 | 3954 | 50222375 |
Irritability | 116.47 | 11.14 | 34 | 378761 | 28392 | 50197937 |
Suicidal ideation | 116.30 | 11.14 | 146 | 378649 | 55239 | 50171090 |
Rectal haemorrhage | 115.33 | 11.14 | 73 | 378722 | 38485 | 50187844 |
Haemorrhage | 115.24 | 11.14 | 138 | 378657 | 53303 | 50173026 |
Cholelithiasis | 114.81 | 11.14 | 71 | 378724 | 37902 | 50188427 |
Vision blurred | 114.73 | 11.14 | 262 | 378533 | 78385 | 50147944 |
Cerebral haemorrhage | 113.35 | 11.14 | 31 | 378764 | 27021 | 50199308 |
Dysarthria | 113.00 | 11.14 | 70 | 378725 | 37333 | 50188996 |
Multiple organ dysfunction syndrome | 112.85 | 11.14 | 126 | 378669 | 50211 | 50176118 |
Blood calcium decreased | 112.32 | 11.14 | 12 | 378783 | 20694 | 50205635 |
Myocardial infarction | 111.81 | 11.14 | 320 | 378475 | 88707 | 50137622 |
Restlessness | 110.97 | 11.14 | 26 | 378769 | 25147 | 50201182 |
Mental status changes | 110.81 | 11.14 | 67 | 378728 | 36205 | 50190124 |
Hepatic function abnormal | 110.62 | 11.14 | 53 | 378742 | 32628 | 50193701 |
Hypokalaemia | 109.25 | 11.14 | 318 | 378477 | 87674 | 50138655 |
Flushing | 107.15 | 11.14 | 212 | 378583 | 66803 | 50159526 |
Pyrexia | 106.85 | 11.14 | 2105 | 376690 | 378098 | 49848231 |
Palpitations | 105.74 | 11.14 | 358 | 378437 | 94148 | 50132181 |
Gastrooesophageal reflux disease | 105.61 | 11.14 | 262 | 378533 | 76166 | 50150163 |
Vertigo | 105.36 | 11.14 | 140 | 378655 | 51692 | 50174637 |
Abnormal behaviour | 105.09 | 11.14 | 12 | 378783 | 19646 | 50206683 |
Cough | 104.36 | 11.14 | 1229 | 377566 | 240035 | 49986294 |
Metastases to bone | 104.13 | 11.14 | 8 | 378787 | 17987 | 50208342 |
Dysgeusia | 102.90 | 11.14 | 84 | 378711 | 38832 | 50187497 |
Elbow deformity | 102.06 | 11.14 | 84 | 378711 | 1302 | 50225027 |
Emotional distress | 100.88 | 11.14 | 44 | 378751 | 28619 | 50197710 |
Colitis | 100.84 | 11.14 | 84 | 378711 | 38445 | 50187884 |
Blood alkaline phosphatase increased | 100.47 | 11.14 | 80 | 378715 | 37446 | 50188883 |
Osteonecrosis of jaw | 99.47 | 11.14 | 60 | 378735 | 32466 | 50193863 |
Accidental overdose | 99.39 | 11.14 | 14 | 378781 | 19519 | 50206810 |
Lethargy | 98.97 | 11.14 | 135 | 378660 | 49297 | 50177032 |
Generalised tonic-clonic seizure | 98.11 | 11.14 | 37 | 378758 | 26273 | 50200056 |
Adverse drug reaction | 97.53 | 11.14 | 728 | 378067 | 54494 | 50171835 |
Pulmonary toxicity | 97.06 | 11.14 | 160 | 378635 | 5402 | 50220927 |
Spinal stenosis | 96.80 | 11.14 | 271 | 378524 | 13279 | 50213050 |
Hypomagnesaemia | 96.16 | 11.14 | 27 | 378768 | 23129 | 50203200 |
Hospitalisation | 96.14 | 11.14 | 230 | 378565 | 67707 | 50158622 |
Arthrodesis | 95.34 | 11.14 | 105 | 378690 | 2380 | 50223949 |
Tuberculin test positive | 94.54 | 11.14 | 118 | 378677 | 3068 | 50223261 |
Urinary retention | 92.50 | 11.14 | 40 | 378755 | 26150 | 50200179 |
SLE arthritis | 92.27 | 11.14 | 58 | 378737 | 572 | 50225757 |
Aphasia | 92.25 | 11.14 | 49 | 378746 | 28445 | 50197884 |
Asthma | 92.25 | 11.14 | 350 | 378445 | 88987 | 50137342 |
Intentional self-injury | 92.23 | 11.14 | 29 | 378766 | 23083 | 50203246 |
Eye disorder | 91.79 | 11.14 | 329 | 378466 | 18410 | 50207919 |
Device dislocation | 91.58 | 11.14 | 24 | 378771 | 21522 | 50204807 |
Chills | 91.52 | 11.14 | 392 | 378403 | 96295 | 50130034 |
Adverse event | 91.40 | 11.14 | 601 | 378194 | 43162 | 50183167 |
Full blood count decreased | 91.05 | 11.14 | 27 | 378768 | 22319 | 50204010 |
Jaundice | 90.77 | 11.14 | 42 | 378753 | 26387 | 50199942 |
Ascites | 90.43 | 11.14 | 81 | 378714 | 35780 | 50190549 |
Nausea | 89.75 | 11.14 | 4343 | 374452 | 701055 | 49525274 |
Nodule | 88.88 | 11.14 | 305 | 378490 | 16698 | 50209631 |
Skin necrosis | 88.37 | 11.14 | 228 | 378567 | 10639 | 50215690 |
Metastases to liver | 88.15 | 11.14 | 21 | 378774 | 20083 | 50206246 |
Renal phospholipidosis | 87.70 | 11.14 | 32 | 378763 | 72 | 50226257 |
Gamma-glutamyltransferase increased | 87.34 | 11.14 | 57 | 378738 | 29566 | 50196763 |
Abdominal distension | 87.23 | 11.14 | 268 | 378527 | 72635 | 50153694 |
Aggression | 86.98 | 11.14 | 25 | 378770 | 21091 | 50205238 |
Haematoma | 86.89 | 11.14 | 61 | 378734 | 30449 | 50195880 |
Respiratory distress | 86.77 | 11.14 | 61 | 378734 | 30428 | 50195901 |
Bone density decreased | 86.61 | 11.14 | 229 | 378566 | 10846 | 50215483 |
Renal impairment | 86.43 | 11.14 | 284 | 378511 | 75377 | 50150952 |
Mucosal inflammation | 86.19 | 11.14 | 104 | 378691 | 40038 | 50186291 |
Neutropenic sepsis | 85.64 | 11.14 | 5 | 378790 | 14142 | 50212187 |
Gastrointestinal pain | 84.96 | 11.14 | 187 | 378608 | 7869 | 50218460 |
Body height below normal | 84.74 | 11.14 | 88 | 378707 | 1861 | 50224468 |
Drug eruption | 84.69 | 11.14 | 376 | 378419 | 23230 | 50203099 |
Adverse reaction | 84.62 | 11.14 | 194 | 378601 | 8392 | 50217937 |
Muscle spasticity | 84.43 | 11.14 | 302 | 378493 | 16882 | 50209447 |
Epilepsy | 84.41 | 11.14 | 28 | 378767 | 21539 | 50204790 |
Lymphocyte count decreased | 84.06 | 11.14 | 46 | 378749 | 26261 | 50200068 |
Blood urea increased | 83.33 | 11.14 | 36 | 378759 | 23549 | 50202780 |
Physical disability | 83.20 | 11.14 | 85 | 378710 | 1762 | 50224567 |
Altered state of consciousness | 83.07 | 11.14 | 30 | 378765 | 21880 | 50204449 |
Joint laxity | 82.93 | 11.14 | 96 | 378699 | 2302 | 50224027 |
Foot deformity | 82.23 | 11.14 | 323 | 378472 | 18887 | 50207442 |
Transient ischaemic attack | 82.12 | 11.14 | 72 | 378723 | 32138 | 50194191 |
Oral mucosal exfoliation | 81.85 | 11.14 | 78 | 378717 | 1481 | 50224848 |
Diabetic ketoacidosis | 81.73 | 11.14 | 17 | 378778 | 17855 | 50208474 |
Breast cancer stage III | 81.67 | 11.14 | 111 | 378684 | 3145 | 50223184 |
Ear pain | 81.55 | 11.14 | 423 | 378372 | 27860 | 50198469 |
Human antichimeric antibody positive | 81.05 | 11.14 | 76 | 378719 | 1413 | 50224916 |
Incorrect dose administered | 81.03 | 11.14 | 149 | 378646 | 48265 | 50178064 |
Erythema | 81.01 | 11.14 | 703 | 378092 | 145711 | 50080618 |
Hypoaesthesia | 80.59 | 11.14 | 589 | 378206 | 126668 | 50099661 |
Osteoporosis | 80.58 | 11.14 | 594 | 378201 | 44285 | 50182044 |
Chronic kidney disease | 80.24 | 11.14 | 108 | 378687 | 39663 | 50186666 |
Acute myocardial infarction | 80.15 | 11.14 | 61 | 378734 | 29212 | 50197117 |
Colitis microscopic | 79.99 | 11.14 | 161 | 378634 | 6359 | 50219970 |
Blood potassium decreased | 79.02 | 11.14 | 96 | 378699 | 36849 | 50189480 |
Upper gastrointestinal haemorrhage | 78.15 | 11.14 | 13 | 378782 | 16022 | 50210307 |
Memory impairment | 78.05 | 11.14 | 317 | 378478 | 79043 | 50147286 |
Rheumatoid factor negative | 77.41 | 11.14 | 51 | 378744 | 549 | 50225780 |
Surgical failure | 76.72 | 11.14 | 60 | 378735 | 861 | 50225468 |
Herpes zoster | 76.59 | 11.14 | 839 | 377956 | 69947 | 50156382 |
Bone marrow failure | 76.36 | 11.14 | 57 | 378738 | 27567 | 50198762 |
Coronary artery disease | 76.33 | 11.14 | 66 | 378729 | 29660 | 50196669 |
Red blood cell sedimentation rate | 76.28 | 11.14 | 113 | 378682 | 3473 | 50222856 |
Small intestinal obstruction | 76.18 | 11.14 | 14 | 378781 | 16054 | 50210275 |
Pancreatitis | 75.99 | 11.14 | 126 | 378669 | 42488 | 50183841 |
Haematochezia | 75.80 | 11.14 | 113 | 378682 | 39769 | 50186560 |
Ulcer | 75.70 | 11.14 | 326 | 378469 | 19874 | 50206455 |
Seronegative arthritis | 75.49 | 11.14 | 85 | 378710 | 1976 | 50224353 |
Swollen tongue | 75.44 | 11.14 | 62 | 378733 | 28568 | 50197761 |
Status epilepticus | 74.72 | 11.14 | 7 | 378788 | 13399 | 50212930 |
Mouth ulceration | 74.58 | 11.14 | 410 | 378385 | 27614 | 50198715 |
Acute respiratory failure | 73.79 | 11.14 | 64 | 378731 | 28718 | 50197611 |
Intentional product misuse | 73.71 | 11.14 | 149 | 378646 | 46585 | 50179744 |
Pneumonia viral | 73.62 | 11.14 | 160 | 378635 | 6674 | 50219655 |
Respiratory depression | 73.46 | 11.14 | 4 | 378791 | 12006 | 50214323 |
Circulatory collapse | 73.13 | 11.14 | 29 | 378766 | 19971 | 50206358 |
Flatulence | 72.54 | 11.14 | 68 | 378727 | 29390 | 50196939 |
Glaucoma | 72.28 | 11.14 | 270 | 378525 | 15416 | 50210913 |
Speech disorder | 72.26 | 11.14 | 96 | 378699 | 35452 | 50190877 |
Drug level increased | 72.01 | 11.14 | 27 | 378768 | 19241 | 50207088 |
Urinary incontinence | 71.98 | 11.14 | 63 | 378732 | 28145 | 50198184 |
Dry skin | 71.33 | 11.14 | 134 | 378661 | 43057 | 50183272 |
Product administration error | 71.31 | 11.14 | 29 | 378766 | 19670 | 50206659 |
Gastritis | 71.29 | 11.14 | 85 | 378710 | 32898 | 50193431 |
Accidental exposure to product | 71.26 | 11.14 | 42 | 378753 | 23015 | 50203314 |
Pallor | 70.65 | 11.14 | 43 | 378752 | 23156 | 50203173 |
Tubulointerstitial nephritis | 70.53 | 11.14 | 14 | 378781 | 15197 | 50211132 |
Epicondylitis | 70.38 | 11.14 | 79 | 378716 | 1830 | 50224499 |
Withdrawal syndrome | 70.32 | 11.14 | 22 | 378773 | 17568 | 50208761 |
Hypervolaemia | 69.99 | 11.14 | 53 | 378742 | 25446 | 50200883 |
Dysuria | 69.95 | 11.14 | 66 | 378729 | 28438 | 50197891 |
Arrhythmia | 69.90 | 11.14 | 87 | 378708 | 33045 | 50193284 |
Wheelchair user | 69.83 | 11.14 | 130 | 378665 | 4842 | 50221487 |
Cardiac disorder | 69.53 | 11.14 | 135 | 378660 | 42844 | 50183485 |
Product prescribing error | 69.41 | 11.14 | 35 | 378760 | 20926 | 50205403 |
Interstitial lung disease | 69.37 | 11.14 | 655 | 378140 | 52521 | 50173808 |
Oxygen saturation decreased | 69.29 | 11.14 | 297 | 378498 | 72951 | 50153378 |
Spinal column injury | 68.89 | 11.14 | 76 | 378719 | 1726 | 50224603 |
Cerebral infarction | 68.70 | 11.14 | 38 | 378757 | 21566 | 50204763 |
Chronic obstructive pulmonary disease | 68.60 | 11.14 | 190 | 378605 | 53245 | 50173084 |
Sciatica | 68.16 | 11.14 | 329 | 378466 | 21053 | 50205276 |
Investigation abnormal | 67.77 | 11.14 | 64 | 378731 | 1201 | 50225128 |
Myoclonus | 67.76 | 11.14 | 13 | 378782 | 14457 | 50211872 |
Dementia | 67.65 | 11.14 | 18 | 378777 | 15979 | 50210350 |
Acute hepatic failure | 67.52 | 11.14 | 17 | 378778 | 15660 | 50210669 |
Ischaemic stroke | 67.34 | 11.14 | 18 | 378777 | 15930 | 50210399 |
Night sweats | 65.86 | 11.14 | 454 | 378341 | 33120 | 50193209 |
Orthostatic hypotension | 65.85 | 11.14 | 74 | 378721 | 29407 | 50196922 |
Body temperature increased | 65.80 | 11.14 | 431 | 378364 | 30910 | 50195419 |
Disseminated intravascular coagulation | 65.75 | 11.14 | 23 | 378772 | 17112 | 50209217 |
Acute myeloid leukaemia | 65.59 | 11.14 | 16 | 378779 | 15058 | 50211271 |
Wheezing | 65.40 | 11.14 | 241 | 378554 | 61806 | 50164523 |
Device related infection | 65.17 | 11.14 | 37 | 378758 | 20698 | 50205631 |
Respiratory disorder | 64.94 | 11.14 | 428 | 378367 | 30759 | 50195570 |
Joint injury | 64.30 | 11.14 | 328 | 378467 | 21461 | 50204868 |
Creatinine renal clearance decreased | 64.15 | 11.14 | 7 | 378788 | 11874 | 50214455 |
Mental disorder | 63.91 | 11.14 | 43 | 378752 | 21948 | 50204381 |
Swelling face | 63.88 | 11.14 | 192 | 378603 | 52403 | 50173926 |
Enthesopathy | 63.81 | 11.14 | 156 | 378639 | 7037 | 50219292 |
Feeling hot | 63.53 | 11.14 | 123 | 378672 | 39079 | 50187250 |
Neurotoxicity | 63.45 | 11.14 | 16 | 378779 | 14724 | 50211605 |
Inappropriate antidiuretic hormone secretion | 63.29 | 11.14 | 11 | 378784 | 13132 | 50213197 |
Blood creatinine increased | 63.09 | 11.14 | 324 | 378471 | 75836 | 50150493 |
Muscular weakness | 62.95 | 11.14 | 434 | 378361 | 94579 | 50131750 |
Complication associated with device | 62.91 | 11.14 | 16 | 378779 | 14639 | 50211690 |
Loose body in joint | 62.80 | 11.14 | 60 | 378735 | 1143 | 50225186 |
Blood lactate dehydrogenase increased | 62.80 | 11.14 | 34 | 378761 | 19528 | 50206801 |
Onychomycosis | 62.45 | 11.14 | 125 | 378670 | 4917 | 50221412 |
Hallucination, visual | 62.36 | 11.14 | 23 | 378772 | 16559 | 50209770 |
Muscle twitching | 62.23 | 11.14 | 19 | 378776 | 15412 | 50210917 |
Rheumatoid lung | 61.77 | 11.14 | 84 | 378711 | 2381 | 50223948 |
Neuroleptic malignant syndrome | 61.53 | 11.14 | 6 | 378789 | 11124 | 50215205 |
Haematemesis | 61.48 | 11.14 | 70 | 378725 | 27655 | 50198674 |
Fear of injection | 61.37 | 11.14 | 139 | 378656 | 5964 | 50220365 |
Inappropriate schedule of product administration | 60.97 | 11.14 | 303 | 378492 | 71528 | 50154801 |
Hepatocellular injury | 60.32 | 11.14 | 63 | 378732 | 25884 | 50200445 |
Psychotic disorder | 60.30 | 11.14 | 45 | 378750 | 21767 | 50204562 |
Weight decreased | 59.58 | 11.14 | 1233 | 377562 | 220012 | 50006317 |
Electrolyte imbalance | 59.40 | 11.14 | 27 | 378768 | 17142 | 50209187 |
Coordination abnormal | 59.31 | 11.14 | 8 | 378787 | 11526 | 50214803 |
Hemiparesis | 58.53 | 11.14 | 39 | 378756 | 20009 | 50206320 |
Injection site pain | 58.36 | 11.14 | 540 | 378255 | 110484 | 50115845 |
Dislocation of vertebra | 58.23 | 11.14 | 92 | 378703 | 2995 | 50223334 |
Clostridium difficile colitis | 58.19 | 11.14 | 30 | 378765 | 17712 | 50208617 |
Vascular access complication | 58.06 | 11.14 | 56 | 378739 | 1080 | 50225249 |
Metastases to central nervous system | 57.60 | 11.14 | 8 | 378787 | 11274 | 50215055 |
Depressed mood | 57.56 | 11.14 | 104 | 378691 | 33919 | 50192410 |
Mania | 57.52 | 11.14 | 7 | 378788 | 10909 | 50215420 |
Cyanosis | 57.21 | 11.14 | 21 | 378774 | 15163 | 50211166 |
Diabetes mellitus inadequate control | 57.11 | 11.14 | 14 | 378781 | 13131 | 50213198 |
Wrist deformity | 56.90 | 11.14 | 69 | 378726 | 1740 | 50224589 |
Delirium | 56.68 | 11.14 | 126 | 378669 | 38066 | 50188263 |
Sleep apnoea syndrome | 56.56 | 11.14 | 57 | 378738 | 23811 | 50202518 |
Head injury | 56.20 | 11.14 | 58 | 378737 | 23962 | 50202367 |
Sleep disorder | 56.12 | 11.14 | 666 | 378129 | 56617 | 50169712 |
Paranoia | 56.12 | 11.14 | 6 | 378789 | 10342 | 50215987 |
Viral upper respiratory tract infection | 56.08 | 11.14 | 146 | 378649 | 6850 | 50219479 |
Red cell distribution width decreased | 55.59 | 11.14 | 54 | 378741 | 1051 | 50225278 |
Blood triglycerides increased | 55.51 | 11.14 | 9 | 378786 | 11303 | 50215026 |
Cellulitis | 55.41 | 11.14 | 307 | 378488 | 70491 | 50155838 |
Obstructive airways disorder | 55.12 | 11.14 | 24 | 378771 | 15628 | 50210701 |
Back injury | 54.90 | 11.14 | 146 | 378649 | 6939 | 50219390 |
Full blood count abnormal | 54.12 | 11.14 | 57 | 378738 | 23331 | 50202998 |
Abortion spontaneous | 54.02 | 11.14 | 148 | 378647 | 41624 | 50184705 |
Mental impairment | 53.96 | 11.14 | 12 | 378783 | 12032 | 50214297 |
Parkinsonism | 53.95 | 11.14 | 3 | 378792 | 8844 | 50217485 |
Nervous system disorder | 53.85 | 11.14 | 27 | 378768 | 16196 | 50210133 |
Haematuria | 53.26 | 11.14 | 68 | 378727 | 25545 | 50200784 |
Basal cell carcinoma | 53.24 | 11.14 | 328 | 378467 | 23028 | 50203301 |
Heart rate increased | 53.09 | 11.14 | 349 | 378446 | 76901 | 50149428 |
Multiple fractures | 53.03 | 11.14 | 138 | 378657 | 6473 | 50219856 |
Back pain | 52.44 | 11.14 | 1250 | 377545 | 218780 | 50007549 |
Type 2 diabetes mellitus | 52.34 | 11.14 | 438 | 378357 | 33937 | 50192392 |
Underdose | 50.89 | 11.14 | 46 | 378749 | 20232 | 50206097 |
Blood creatine phosphokinase increased | 50.79 | 11.14 | 74 | 378721 | 26293 | 50200036 |
Anuria | 50.79 | 11.14 | 11 | 378784 | 11233 | 50215096 |
Blood sodium decreased | 50.69 | 11.14 | 50 | 378745 | 21097 | 50205232 |
Thrombosis | 50.61 | 11.14 | 230 | 378565 | 55603 | 50170726 |
Abdominal pain lower | 50.37 | 11.14 | 53 | 378742 | 21703 | 50204626 |
Subacute cutaneous lupus erythematosus | 50.31 | 11.14 | 72 | 378723 | 2143 | 50224186 |
Extrapyramidal disorder | 50.23 | 11.14 | 13 | 378782 | 11757 | 50214572 |
Cholestasis | 50.21 | 11.14 | 70 | 378725 | 25331 | 50200998 |
Vaginal haemorrhage | 50.20 | 11.14 | 66 | 378729 | 24485 | 50201844 |
Product label confusion | 50.15 | 11.14 | 37 | 378758 | 484 | 50225845 |
Hypothermia | 49.91 | 11.14 | 14 | 378781 | 12002 | 50214327 |
Coagulopathy | 49.63 | 11.14 | 37 | 378758 | 17907 | 50208422 |
Akathisia | 49.54 | 11.14 | 3 | 378792 | 8226 | 50218103 |
Anger | 49.37 | 11.14 | 12 | 378783 | 11321 | 50215008 |
Device issue | 49.29 | 11.14 | 46 | 378749 | 19926 | 50206403 |
Infusion site reaction | 49.07 | 11.14 | 71 | 378724 | 2135 | 50224194 |
Mean platelet volume decreased | 49.02 | 11.14 | 61 | 378734 | 1581 | 50224748 |
Therapy non-responder | 48.58 | 11.14 | 590 | 378205 | 50432 | 50175897 |
Multiple sclerosis | 48.49 | 11.14 | 49 | 378746 | 20444 | 50205885 |
Pulmonary congestion | 48.22 | 11.14 | 27 | 378768 | 15220 | 50211109 |
Alanine aminotransferase increased | 48.07 | 11.14 | 426 | 378369 | 87933 | 50138396 |
Foot operation | 47.29 | 11.14 | 118 | 378677 | 5392 | 50220937 |
Tachypnoea | 47.29 | 11.14 | 25 | 378770 | 14552 | 50211777 |
Blood glucose decreased | 47.28 | 11.14 | 40 | 378755 | 18171 | 50208158 |
Poisoning deliberate | 47.28 | 11.14 | 3 | 378792 | 7909 | 50218420 |
Cytomegalovirus infection | 47.20 | 11.14 | 39 | 378756 | 17923 | 50208406 |
Poisoning | 47.15 | 11.14 | 17 | 378778 | 12412 | 50213917 |
Mydriasis | 46.79 | 11.14 | 11 | 378784 | 10616 | 50215713 |
Pulmonary hypertension | 46.58 | 11.14 | 114 | 378681 | 33303 | 50193026 |
Ocular toxicity | 46.47 | 11.14 | 36 | 378759 | 509 | 50225820 |
Blood magnesium decreased | 46.36 | 11.14 | 13 | 378782 | 11147 | 50215182 |
Confusional state | 46.32 | 11.14 | 1049 | 377746 | 184879 | 50041450 |
Device difficult to use | 46.04 | 11.14 | 9 | 378786 | 9877 | 50216452 |
Nightmare | 46.01 | 11.14 | 32 | 378763 | 16054 | 50210275 |
Leukocytosis | 45.86 | 11.14 | 61 | 378734 | 22518 | 50203811 |
Renal tubular necrosis | 45.82 | 11.14 | 10 | 378785 | 10158 | 50216171 |
Ankle arthroplasty | 45.04 | 11.14 | 49 | 378746 | 1095 | 50225234 |
Incontinence | 44.63 | 11.14 | 10 | 378785 | 9975 | 50216354 |
Bone density abnormal | 44.51 | 11.14 | 81 | 378714 | 2964 | 50223365 |
Infective pulmonary exacerbation of cystic fibrosis | 44.43 | 11.14 | 4 | 378791 | 7905 | 50218424 |
Renal disorder | 43.96 | 11.14 | 87 | 378708 | 27418 | 50198911 |
Hyperthyroidism | 43.95 | 11.14 | 18 | 378777 | 12157 | 50214172 |
Ileus | 43.94 | 11.14 | 22 | 378773 | 13207 | 50213122 |
Antibody test positive | 43.76 | 11.14 | 69 | 378726 | 2242 | 50224087 |
Metastases to lung | 43.66 | 11.14 | 14 | 378781 | 11006 | 50215323 |
Muscle rigidity | 43.62 | 11.14 | 10 | 378785 | 9819 | 50216510 |
Neck pain | 43.18 | 11.14 | 633 | 378162 | 56434 | 50169895 |
Hypersomnia | 43.10 | 11.14 | 31 | 378764 | 15283 | 50211046 |
Onychomadesis | 43 | 11.14 | 87 | 378708 | 3449 | 50222880 |
Hypophosphataemia | 42.88 | 11.14 | 6 | 378789 | 8408 | 50217921 |
Heart rate irregular | 42.80 | 11.14 | 49 | 378746 | 19311 | 50207018 |
Skin exfoliation | 42.78 | 11.14 | 120 | 378675 | 33492 | 50192837 |
Feeling cold | 42.56 | 11.14 | 50 | 378745 | 19481 | 50206848 |
Blood albumin decreased | 42.49 | 11.14 | 23 | 378772 | 13213 | 50213116 |
Transfusion | 42.06 | 11.14 | 22 | 378773 | 12883 | 50213446 |
Haemorrhage intracranial | 41.97 | 11.14 | 20 | 378775 | 12354 | 50213975 |
Intestinal obstruction | 41.70 | 11.14 | 84 | 378711 | 26299 | 50200030 |
Pleural thickening | 41.68 | 11.14 | 72 | 378723 | 2527 | 50223802 |
Ovarian neoplasm | 41.67 | 11.14 | 41 | 378754 | 811 | 50225518 |
Anal incontinence | 41.45 | 11.14 | 17 | 378778 | 11473 | 50214856 |
Hot flush | 41.21 | 11.14 | 180 | 378615 | 43989 | 50182340 |
Mycotic allergy | 41.16 | 11.14 | 40 | 378755 | 779 | 50225550 |
Glycosylated haemoglobin increased | 41.10 | 11.14 | 14 | 378781 | 10592 | 50215737 |
Paraesthesia oral | 41.08 | 11.14 | 20 | 378775 | 12201 | 50214128 |
Malnutrition | 40.79 | 11.14 | 24 | 378771 | 13165 | 50213164 |
Transaminases abnormal | 40.53 | 11.14 | 34 | 378761 | 542 | 50225787 |
Brain oedema | 40.44 | 11.14 | 21 | 378774 | 12349 | 50213980 |
Phospholipidosis | 40.38 | 11.14 | 16 | 378779 | 49 | 50226280 |
Aspartate aminotransferase increased | 40.27 | 11.14 | 381 | 378414 | 77617 | 50148712 |
Osteoporotic fracture | 40.19 | 11.14 | 79 | 378716 | 3066 | 50223263 |
Shock haemorrhagic | 40.14 | 11.14 | 7 | 378788 | 8337 | 50217992 |
Oedema | 40.11 | 11.14 | 334 | 378461 | 69847 | 50156482 |
Loss of consciousness | 40.02 | 11.14 | 545 | 378250 | 103808 | 50122521 |
Ataxia | 40 | 11.14 | 27 | 378768 | 13759 | 50212570 |
Aspiration | 39.98 | 11.14 | 10 | 378785 | 9254 | 50217075 |
Myelosuppression | 39.86 | 11.14 | 26 | 378769 | 13491 | 50212838 |
Presbyacusis | 39.51 | 11.14 | 73 | 378722 | 2703 | 50223626 |
Bone swelling | 39.45 | 11.14 | 47 | 378748 | 1163 | 50225166 |
Subdural haematoma | 39.42 | 11.14 | 24 | 378771 | 12923 | 50213406 |
Pollakiuria | 39.37 | 11.14 | 74 | 378721 | 23777 | 50202552 |
Sinus bradycardia | 39.36 | 11.14 | 25 | 378770 | 13158 | 50213171 |
Dialysis | 39.19 | 11.14 | 11 | 378784 | 9427 | 50216902 |
Cholecystitis | 39.14 | 11.14 | 28 | 378767 | 13843 | 50212486 |
Sinus tachycardia | 39.14 | 11.14 | 62 | 378733 | 21292 | 50205037 |
Cutaneous vasculitis | 39.12 | 11.14 | 95 | 378700 | 4267 | 50222062 |
Haemoptysis | 39.08 | 11.14 | 83 | 378712 | 25490 | 50200839 |
Amnesia | 38.95 | 11.14 | 173 | 378622 | 42087 | 50184242 |
Amenorrhoea | 38.94 | 11.14 | 8 | 378787 | 8476 | 50217853 |
Dyspnoea exertional | 38.55 | 11.14 | 225 | 378570 | 51008 | 50175321 |
Mean cell volume decreased | 38.51 | 11.14 | 70 | 378725 | 2559 | 50223770 |
Therapy cessation | 38.44 | 11.14 | 86 | 378709 | 25925 | 50200404 |
Mood altered | 38.44 | 11.14 | 24 | 378771 | 12749 | 50213580 |
Eye swelling | 38.35 | 11.14 | 57 | 378738 | 20087 | 50206242 |
Hypoalbuminaemia | 38.24 | 11.14 | 13 | 378782 | 9847 | 50216482 |
Pulmonary arterial hypertension | 38.19 | 11.14 | 58 | 378737 | 20261 | 50206068 |
Contusion | 38.17 | 11.14 | 1105 | 377690 | 111078 | 50115251 |
Laryngeal disorder | 38.14 | 11.14 | 40 | 378755 | 856 | 50225473 |
Lip swelling | 38.04 | 11.14 | 80 | 378715 | 24656 | 50201673 |
Nervousness | 38.01 | 11.14 | 95 | 378700 | 27556 | 50198773 |
Angioedema | 37.98 | 11.14 | 149 | 378646 | 37527 | 50188802 |
Blood pressure increased | 37.88 | 11.14 | 735 | 378060 | 132397 | 50093932 |
Neck mass | 37.71 | 11.14 | 80 | 378715 | 3281 | 50223048 |
Angina pectoris | 37.56 | 11.14 | 88 | 378707 | 26100 | 50200229 |
Lipase increased | 37.29 | 11.14 | 9 | 378786 | 8532 | 50217797 |
Haematotoxicity | 37.17 | 11.14 | 7 | 378788 | 7888 | 50218441 |
Sensitivity to weather change | 37.10 | 11.14 | 114 | 378681 | 5887 | 50220442 |
Lupus vasculitis | 36.88 | 11.14 | 30 | 378765 | 457 | 50225872 |
International normalised ratio fluctuation | 36.87 | 11.14 | 62 | 378733 | 2128 | 50224201 |
Pericardial effusion | 36.69 | 11.14 | 86 | 378709 | 25503 | 50200826 |
Skin discolouration | 36.68 | 11.14 | 124 | 378671 | 32633 | 50193696 |
Urine output decreased | 36.66 | 11.14 | 16 | 378779 | 10405 | 50215924 |
Psychomotor hyperactivity | 36.53 | 11.14 | 12 | 378783 | 9289 | 50217040 |
Acquired pigmented retinopathy | 36.42 | 11.14 | 10 | 378785 | 3 | 50226326 |
Synovial cyst | 36.33 | 11.14 | 139 | 378656 | 8027 | 50218302 |
Retching | 36.25 | 11.14 | 26 | 378769 | 12836 | 50213493 |
Pleural fibrosis | 36.19 | 11.14 | 79 | 378716 | 3305 | 50223024 |
Diplopia | 36.18 | 11.14 | 55 | 378740 | 19205 | 50207124 |
Delusion | 35.98 | 11.14 | 17 | 378778 | 10552 | 50215777 |
Supraventricular tachycardia | 35.91 | 11.14 | 26 | 378769 | 12775 | 50213554 |
Aplastic anaemia | 35.90 | 11.14 | 7 | 378788 | 7696 | 50218633 |
Drug resistance | 35.89 | 11.14 | 54 | 378741 | 18935 | 50207394 |
Hip fracture | 35.72 | 11.14 | 89 | 378706 | 25842 | 50200487 |
Pharyngitis | 35.71 | 11.14 | 239 | 378556 | 17264 | 50209065 |
Subarachnoid haemorrhage | 35.67 | 11.14 | 18 | 378777 | 10758 | 50215571 |
Injection site reaction | 35.53 | 11.14 | 549 | 378246 | 49483 | 50176846 |
Acidosis | 35.51 | 11.14 | 16 | 378779 | 10211 | 50216118 |
Overlap syndrome | 35.39 | 11.14 | 33 | 378762 | 609 | 50225720 |
Cholecystitis chronic | 35.38 | 11.14 | 14 | 378781 | 9655 | 50216674 |
Bronchitis chronic | 35.37 | 11.14 | 85 | 378710 | 3792 | 50222537 |
Clostridium difficile infection | 35.28 | 11.14 | 87 | 378708 | 25352 | 50200977 |
Retinitis | 35.26 | 11.14 | 56 | 378739 | 1831 | 50224498 |
Acute coronary syndrome | 35.25 | 11.14 | 13 | 378782 | 9361 | 50216968 |
Staphylococcal infection | 35.17 | 11.14 | 142 | 378653 | 35474 | 50190855 |
Extremity contracture | 35.09 | 11.14 | 45 | 378750 | 1203 | 50225126 |
Restrictive cardiomyopathy | 35.03 | 11.14 | 24 | 378771 | 277 | 50226052 |
Pancreatitis acute | 34.97 | 11.14 | 79 | 378716 | 23733 | 50202596 |
Injection site erythema | 34.97 | 11.14 | 375 | 378420 | 74561 | 50151768 |
Graft versus host disease | 34.96 | 11.14 | 3 | 378792 | 6163 | 50220166 |
Glomerular filtration rate decreased | 34.92 | 11.14 | 22 | 378773 | 11630 | 50214699 |
Soft tissue disorder | 34.87 | 11.14 | 89 | 378706 | 4125 | 50222204 |
Hypocalcaemia | 34.68 | 11.14 | 95 | 378700 | 26721 | 50199608 |
Ageusia | 34.54 | 11.14 | 22 | 378773 | 11561 | 50214768 |
Large intestine perforation | 34.53 | 11.14 | 7 | 378788 | 7487 | 50218842 |
Frequent bowel movements | 34.42 | 11.14 | 32 | 378763 | 13886 | 50212443 |
Ear infection | 34.41 | 11.14 | 321 | 378474 | 25649 | 50200680 |
Faeces discoloured | 34.37 | 11.14 | 42 | 378753 | 16082 | 50210247 |
Haemodialysis | 34.26 | 11.14 | 10 | 378785 | 8352 | 50217977 |
Faecaloma | 34.11 | 11.14 | 6 | 378789 | 7102 | 50219227 |
Taste disorder | 34.02 | 11.14 | 10 | 378785 | 8314 | 50218015 |
Hallucination, auditory | 33.92 | 11.14 | 19 | 378776 | 10709 | 50215620 |
Drug specific antibody | 33.88 | 11.14 | 54 | 378741 | 1771 | 50224558 |
Panic attack | 33.73 | 11.14 | 58 | 378737 | 19284 | 50207045 |
Abnormal dreams | 33.62 | 11.14 | 14 | 378781 | 9363 | 50216966 |
Hepatic encephalopathy | 33.58 | 11.14 | 15 | 378780 | 9621 | 50216708 |
Metastases to lymph nodes | 33.56 | 11.14 | 6 | 378789 | 7018 | 50219311 |
Thrombotic microangiopathy | 33.39 | 11.14 | 12 | 378783 | 8779 | 50217550 |
Breast cancer metastatic | 33.29 | 11.14 | 18 | 378777 | 10346 | 50215983 |
Shock | 33.28 | 11.14 | 65 | 378730 | 20585 | 50205744 |
Right ventricular failure | 33.24 | 11.14 | 42 | 378753 | 15851 | 50210478 |
Sensory disturbance | 33.22 | 11.14 | 24 | 378771 | 11805 | 50214524 |
Caesarean section | 33.06 | 11.14 | 41 | 378754 | 15598 | 50210731 |
Myopathy toxic | 32.68 | 11.14 | 26 | 378769 | 383 | 50225946 |
Presyncope | 32.60 | 11.14 | 84 | 378711 | 24114 | 50202215 |
Dystonia | 32.46 | 11.14 | 25 | 378770 | 11901 | 50214428 |
Hypoacusis | 32.40 | 11.14 | 66 | 378729 | 20581 | 50205748 |
Deafness neurosensory | 32.13 | 11.14 | 90 | 378705 | 4411 | 50221918 |
Polyuria | 32.10 | 11.14 | 7 | 378788 | 7114 | 50219215 |
Infiltration anaesthesia | 32.08 | 11.14 | 18 | 378777 | 141 | 50226188 |
Medication error | 31.96 | 11.14 | 150 | 378645 | 35954 | 50190375 |
Cardiogenic shock | 31.83 | 11.14 | 42 | 378753 | 15557 | 50210772 |
Hair follicle tumour benign | 31.78 | 11.14 | 25 | 378770 | 362 | 50225967 |
Live birth | 31.66 | 11.14 | 221 | 378574 | 16187 | 50210142 |
Face oedema | 31.57 | 11.14 | 53 | 378742 | 17786 | 50208543 |
Upper respiratory tract infection | 31.47 | 11.14 | 328 | 378467 | 65570 | 50160759 |
Brain injury | 31.34 | 11.14 | 4 | 378791 | 6010 | 50220319 |
Rash erythematous | 31.33 | 11.14 | 144 | 378651 | 34708 | 50191621 |
Stress cardiomyopathy | 31.28 | 11.14 | 10 | 378785 | 7877 | 50218452 |
White blood cell count increased | 30.99 | 11.14 | 187 | 378608 | 42053 | 50184276 |
Rash macular | 30.78 | 11.14 | 61 | 378734 | 19216 | 50207113 |
Fracture | 30.73 | 11.14 | 49 | 378746 | 16784 | 50209545 |
Lymphoedema | 30.55 | 11.14 | 15 | 378780 | 9107 | 50217222 |
Enterocolitis | 30.54 | 11.14 | 6 | 378789 | 6561 | 50219768 |
Joint arthroplasty | 30.43 | 11.14 | 56 | 378739 | 2067 | 50224262 |
Prothrombin time prolonged | 30.42 | 11.14 | 14 | 378781 | 8824 | 50217505 |
Eosinophil count increased | 30.37 | 11.14 | 14 | 378781 | 8816 | 50217513 |
Bacteraemia | 30.34 | 11.14 | 38 | 378757 | 14395 | 50211934 |
Accident | 30.25 | 11.14 | 96 | 378699 | 5045 | 50221284 |
Mesenteritis | 30.21 | 11.14 | 17 | 378778 | 134 | 50226195 |
Drug reaction with eosinophilia and systemic symptoms | 30.21 | 11.14 | 110 | 378685 | 28314 | 50198015 |
Intermenstrual bleeding | 30.11 | 11.14 | 7 | 378788 | 6807 | 50219522 |
Ejection fraction decreased | 30.10 | 11.14 | 58 | 378737 | 18462 | 50207867 |
Hypothyroidism | 30.08 | 11.14 | 142 | 378653 | 33983 | 50192346 |
Cholecystitis acute | 30.04 | 11.14 | 8 | 378787 | 7098 | 50219231 |
Agranulocytosis | 29.91 | 11.14 | 73 | 378722 | 21348 | 50204981 |
Labelled drug-drug interaction medication error | 29.76 | 11.14 | 21 | 378774 | 10456 | 50215873 |
Colitis ischaemic | 29.69 | 11.14 | 17 | 378778 | 9466 | 50216863 |
Myelodysplastic syndrome | 29.61 | 11.14 | 42 | 378753 | 15090 | 50211239 |
Myocardial ischaemia | 29.55 | 11.14 | 26 | 378769 | 11587 | 50214742 |
Influenza like illness | 29.52 | 11.14 | 281 | 378514 | 57178 | 50169151 |
Petechiae | 29.51 | 11.14 | 30 | 378765 | 12482 | 50213847 |
Histoplasmosis disseminated | 29.50 | 11.14 | 42 | 378753 | 1244 | 50225085 |
Anti-cyclic citrullinated peptide antibody | 29.41 | 11.14 | 47 | 378748 | 1545 | 50224784 |
Bloody discharge | 29.41 | 11.14 | 40 | 378755 | 1134 | 50225195 |
Coeliac disease | 29.40 | 11.14 | 136 | 378659 | 8549 | 50217780 |
Neck deformity | 29.40 | 11.14 | 53 | 378742 | 1925 | 50224404 |
Wrist surgery | 29.38 | 11.14 | 33 | 378762 | 765 | 50225564 |
Suspected suicide | 29.32 | 11.14 | 3 | 378792 | 5354 | 50220975 |
Premature labour | 28.83 | 11.14 | 26 | 378769 | 11450 | 50214879 |
Arteriosclerosis | 28.81 | 11.14 | 16 | 378779 | 9061 | 50217268 |
Vasculitic rash | 28.81 | 11.14 | 41 | 378754 | 1214 | 50225115 |
Salivary hypersecretion | 28.67 | 11.14 | 7 | 378788 | 6584 | 50219745 |
Heavy menstrual bleeding | 28.58 | 11.14 | 45 | 378750 | 15492 | 50210837 |
Anovulatory cycle | 28.55 | 11.14 | 16 | 378779 | 125 | 50226204 |
Incorrect product administration duration | 28.51 | 11.14 | 17 | 378778 | 9258 | 50217071 |
Central nervous system lesion | 28.32 | 11.14 | 18 | 378777 | 9471 | 50216858 |
Hypovolaemia | 28.19 | 11.14 | 18 | 378777 | 9447 | 50216882 |
Stevens-Johnson syndrome | 28.17 | 11.14 | 77 | 378718 | 21675 | 50204654 |
Large intestine polyp | 27.86 | 11.14 | 10 | 378785 | 7322 | 50219007 |
Bradyphrenia | 27.82 | 11.14 | 6 | 378789 | 6146 | 50220183 |
Metabolic encephalopathy | 27.69 | 11.14 | 3 | 378792 | 5118 | 50221211 |
Hyperreflexia | 27.67 | 11.14 | 3 | 378792 | 5115 | 50221214 |
Hiatus hernia | 27.64 | 11.14 | 60 | 378735 | 18284 | 50208045 |
Infusion site pain | 27.56 | 11.14 | 31 | 378764 | 12315 | 50214014 |
Electrocardiogram U-wave abnormality | 27.56 | 11.14 | 10 | 378785 | 22 | 50226307 |
Post procedural haemorrhage | 27.48 | 11.14 | 10 | 378785 | 7260 | 50219069 |
Acute pulmonary oedema | 27.46 | 11.14 | 10 | 378785 | 7257 | 50219072 |
Activated partial thromboplastin time prolonged | 27.46 | 11.14 | 7 | 378788 | 6395 | 50219934 |
Hospice care | 27.43 | 11.14 | 5 | 378790 | 5767 | 50220562 |
Injection site mass | 27.36 | 11.14 | 47 | 378748 | 15633 | 50210696 |
Asphyxia | 27.35 | 11.14 | 4 | 378791 | 5423 | 50220906 |
Hypoaesthesia oral | 27.32 | 11.14 | 24 | 378771 | 10704 | 50215625 |
Mean cell haemoglobin decreased | 27.30 | 11.14 | 70 | 378725 | 3253 | 50223076 |
Blood magnesium increased | 27.20 | 11.14 | 64 | 378731 | 2816 | 50223513 |
Anhedonia | 27.17 | 11.14 | 19 | 378776 | 9505 | 50216824 |
Diverticulitis | 27.07 | 11.14 | 373 | 378422 | 32809 | 50193520 |
Visual acuity reduced | 27.06 | 11.14 | 70 | 378725 | 20069 | 50206260 |
Eyelid oedema | 26.85 | 11.14 | 19 | 378776 | 9447 | 50216882 |
Infusion site erythema | 26.82 | 11.14 | 16 | 378779 | 8711 | 50217618 |
Optical coherence tomography abnormal | 26.78 | 11.14 | 9 | 378786 | 14 | 50226315 |
Pathological fracture | 26.70 | 11.14 | 12 | 378783 | 7670 | 50218659 |
Device malfunction | 26.69 | 11.14 | 45 | 378750 | 15076 | 50211253 |
Diarrhoea haemorrhagic | 26.66 | 11.14 | 12 | 378783 | 7663 | 50218666 |
Laboratory test abnormal | 26.57 | 11.14 | 87 | 378708 | 23121 | 50203208 |
Throat irritation | 26.55 | 11.14 | 126 | 378669 | 30113 | 50196216 |
Eye pain | 26.50 | 11.14 | 116 | 378679 | 28333 | 50197996 |
Pemphigoid | 26.23 | 11.14 | 6 | 378789 | 5901 | 50220428 |
Hyperbilirubinaemia | 26.12 | 11.14 | 20 | 378775 | 9550 | 50216779 |
Throat tightness | 26.11 | 11.14 | 75 | 378720 | 20772 | 50205557 |
Long QT syndrome | 25.95 | 11.14 | 64 | 378731 | 2903 | 50223426 |
Gingivitis | 25.92 | 11.14 | 11 | 378784 | 7273 | 50219056 |
Needle issue | 25.86 | 11.14 | 11 | 378784 | 7264 | 50219065 |
Mycobacterium tuberculosis complex test positive | 25.84 | 11.14 | 47 | 378748 | 1719 | 50224610 |
Alanine aminotransferase abnormal | 25.74 | 11.14 | 79 | 378716 | 4077 | 50222252 |
Cold sweat | 25.70 | 11.14 | 25 | 378770 | 10619 | 50215710 |
Disease susceptibility | 25.42 | 11.14 | 17 | 378778 | 188 | 50226141 |
Tenderness | 25.37 | 11.14 | 231 | 378564 | 18334 | 50207995 |
Cutaneous coccidioidomycosis | 25.37 | 11.14 | 9 | 378786 | 18 | 50226311 |
Oesophagitis | 25.35 | 11.14 | 38 | 378757 | 13345 | 50212984 |
Oliguria | 25.34 | 11.14 | 15 | 378780 | 8201 | 50218128 |
Eye pruritus | 25.32 | 11.14 | 34 | 378761 | 12500 | 50213829 |
Skin ulcer | 25.25 | 11.14 | 388 | 378407 | 34930 | 50191399 |
Jaundice cholestatic | 25.23 | 11.14 | 4 | 378791 | 5107 | 50221222 |
Ankle operation | 25.15 | 11.14 | 38 | 378757 | 1189 | 50225140 |
Lower gastrointestinal haemorrhage | 25.11 | 11.14 | 10 | 378785 | 6869 | 50219460 |
Transplant rejection | 25.08 | 11.14 | 21 | 378774 | 9588 | 50216741 |
Crohn's disease | 25.02 | 11.14 | 3 | 378792 | 4730 | 50221599 |
Hemiplegia | 24.93 | 11.14 | 12 | 378783 | 7369 | 50218960 |
Pulseless electrical activity | 24.88 | 11.14 | 10 | 378785 | 6831 | 50219498 |
Hypotonia | 24.87 | 11.14 | 15 | 378780 | 8119 | 50218210 |
Renal injury | 24.80 | 11.14 | 17 | 378778 | 8594 | 50217735 |
Troponin increased | 24.78 | 11.14 | 15 | 378780 | 8103 | 50218226 |
Stress at work | 24.75 | 11.14 | 35 | 378760 | 1030 | 50225299 |
Device breakage | 24.75 | 11.14 | 21 | 378774 | 9526 | 50216803 |
Hepatic cytolysis | 24.70 | 11.14 | 15 | 378780 | 8088 | 50218241 |
Oral discomfort | 24.58 | 11.14 | 122 | 378673 | 7895 | 50218434 |
Proctalgia | 24.50 | 11.14 | 4 | 378791 | 4999 | 50221330 |
Skin burning sensation | 24.50 | 11.14 | 24 | 378771 | 10161 | 50216168 |
Pancreatic carcinoma | 24.43 | 11.14 | 8 | 378787 | 6206 | 50220123 |
Diverticulum | 24.41 | 11.14 | 26 | 378769 | 10588 | 50215741 |
Apathy | 24.40 | 11.14 | 13 | 378782 | 7535 | 50218794 |
Burning sensation | 24.31 | 11.14 | 220 | 378575 | 45226 | 50181103 |
Haemodynamic instability | 24.26 | 11.14 | 15 | 378780 | 8009 | 50218320 |
Intestinal sepsis | 24.24 | 11.14 | 18 | 378777 | 238 | 50226091 |
Device leakage | 24.13 | 11.14 | 7 | 378788 | 5871 | 50220458 |
Unintended pregnancy | 24.12 | 11.14 | 4 | 378791 | 4942 | 50221387 |
Device use error | 24.10 | 11.14 | 5 | 378790 | 5261 | 50221068 |
Lupus-like syndrome | 24.02 | 11.14 | 137 | 378658 | 9354 | 50216975 |
Fistula | 23.97 | 11.14 | 16 | 378779 | 8202 | 50218127 |
Thyroid neoplasm | 23.94 | 11.14 | 69 | 378726 | 3438 | 50222891 |
Muscle tightness | 23.85 | 11.14 | 25 | 378770 | 10255 | 50216074 |
Klebsiella infection | 23.84 | 11.14 | 12 | 378783 | 7182 | 50219147 |
Lupus myocarditis | 23.79 | 11.14 | 11 | 378784 | 54 | 50226275 |
Limb operation | 23.75 | 11.14 | 67 | 378728 | 3297 | 50223032 |
Toxic encephalopathy | 23.71 | 11.14 | 6 | 378789 | 5509 | 50220820 |
Pulmonary mass | 23.69 | 11.14 | 229 | 378566 | 18476 | 50207853 |
Application site erythema | 23.69 | 11.14 | 3 | 378792 | 4535 | 50221794 |
Bone cyst | 23.67 | 11.14 | 49 | 378746 | 1975 | 50224354 |
Failure to thrive | 23.61 | 11.14 | 9 | 378786 | 6349 | 50219980 |
Bone disorder | 23.47 | 11.14 | 229 | 378566 | 18523 | 50207806 |
Chromaturia | 23.44 | 11.14 | 46 | 378749 | 14544 | 50211785 |
Mass excision | 23.44 | 11.14 | 18 | 378777 | 251 | 50226078 |
Hypertensive crisis | 23.35 | 11.14 | 39 | 378756 | 13115 | 50213214 |
Cartilage atrophy | 23.28 | 11.14 | 15 | 378780 | 155 | 50226174 |
Device occlusion | 23.25 | 11.14 | 8 | 378787 | 6015 | 50220314 |
White blood cell count abnormal | 23.23 | 11.14 | 6 | 378789 | 5434 | 50220895 |
Tuberculosis | 23.23 | 11.14 | 142 | 378653 | 9941 | 50216388 |
Malaise | 23.21 | 11.14 | 2179 | 376616 | 333353 | 49892976 |
Dry mouth | 23.15 | 11.14 | 289 | 378506 | 55889 | 50170440 |
Hypercalcaemia | 23.08 | 11.14 | 272 | 378523 | 23080 | 50203249 |
COVID-19 treatment | 23.05 | 11.14 | 13 | 378782 | 103 | 50226226 |
Sudden death | 23.04 | 11.14 | 20 | 378775 | 8971 | 50217358 |
Hyperventilation | 23.03 | 11.14 | 6 | 378789 | 5403 | 50220926 |
Drug level decreased | 23.03 | 11.14 | 10 | 378785 | 6523 | 50219806 |
Retinal degeneration | 22.88 | 11.14 | 28 | 378767 | 713 | 50225616 |
Lacrimation increased | 22.88 | 11.14 | 59 | 378736 | 16933 | 50209396 |
Product substitution issue | 22.86 | 11.14 | 44 | 378751 | 14013 | 50212316 |
Cystitis | 22.86 | 11.14 | 218 | 378577 | 44346 | 50181983 |
Pain in extremity | 22.62 | 11.14 | 2353 | 376442 | 270512 | 49955817 |
Blood calcium increased | 22.55 | 11.14 | 15 | 378780 | 7704 | 50218625 |
Thinking abnormal | 22.49 | 11.14 | 23 | 378772 | 9544 | 50216785 |
Fear | 22.41 | 11.14 | 47 | 378748 | 14502 | 50211827 |
Influenza | 22.32 | 11.14 | 505 | 378290 | 89033 | 50137296 |
Dysphonia | 22.26 | 11.14 | 185 | 378610 | 38707 | 50187622 |
Pustular psoriasis | 22.21 | 11.14 | 73 | 378722 | 3908 | 50222421 |
Migraine | 22.20 | 11.14 | 413 | 378382 | 74867 | 50151462 |
Diabetic eye disease | 22.11 | 11.14 | 14 | 378781 | 140 | 50226189 |
Haemorrhoids | 22.10 | 11.14 | 71 | 378724 | 18982 | 50207347 |
Arteriosclerosis coronary artery | 22.09 | 11.14 | 15 | 378780 | 7621 | 50218708 |
Hepatic necrosis | 22.01 | 11.14 | 6 | 378789 | 5242 | 50221087 |
Blood thyroid stimulating hormone increased | 22.00 | 11.14 | 9 | 378786 | 6083 | 50220246 |
Nail disorder | 21.91 | 11.14 | 136 | 378659 | 9572 | 50216757 |
Chorioretinitis | 21.89 | 11.14 | 22 | 378773 | 447 | 50225882 |
Hydronephrosis | 21.88 | 11.14 | 19 | 378776 | 8522 | 50217807 |
Venoocclusive liver disease | 21.81 | 11.14 | 3 | 378792 | 4258 | 50222071 |
Escherichia infection | 21.77 | 11.14 | 30 | 378765 | 10911 | 50215418 |
Cushingoid | 21.72 | 11.14 | 103 | 378692 | 6542 | 50219787 |
Infective exacerbation of bronchiectasis | 21.69 | 11.14 | 19 | 378776 | 322 | 50226007 |
Fundoscopy abnormal | 21.60 | 11.14 | 7 | 378788 | 9 | 50226320 |
Body tinea | 21.59 | 11.14 | 37 | 378758 | 1290 | 50225039 |
Polyneuropathy | 21.50 | 11.14 | 36 | 378759 | 12095 | 50214234 |
Thirst | 21.40 | 11.14 | 29 | 378766 | 10621 | 50215708 |
Musculoskeletal chest pain | 21.37 | 11.14 | 69 | 378726 | 18417 | 50207912 |
Femoral neck fracture | 21.29 | 11.14 | 15 | 378780 | 7475 | 50218854 |
Sinus disorder | 21.26 | 11.14 | 69 | 378726 | 18389 | 50207940 |
Ankylosing spondylitis | 21.23 | 11.14 | 108 | 378687 | 7057 | 50219272 |
Femur fracture | 21.10 | 11.14 | 396 | 378399 | 37068 | 50189261 |
Pelvic pain | 21.08 | 11.14 | 32 | 378763 | 11181 | 50215148 |
Blood glucose fluctuation | 21.03 | 11.14 | 3 | 378792 | 4143 | 50222186 |
Product storage error | 21.00 | 11.14 | 37 | 378758 | 12187 | 50214142 |
Coma scale abnormal | 20.88 | 11.14 | 5 | 378790 | 4766 | 50221563 |
Synovial fluid analysis | 20.76 | 11.14 | 41 | 378754 | 1597 | 50224732 |
Liver injury | 20.71 | 11.14 | 280 | 378515 | 24526 | 50201803 |
Foetal exposure during pregnancy | 20.66 | 11.14 | 120 | 378675 | 27239 | 50199090 |
Major depression | 20.63 | 11.14 | 13 | 378782 | 6871 | 50219458 |
Pregnancy with contraceptive device | 20.57 | 11.14 | 3 | 378792 | 4076 | 50222253 |
Seasonal allergy | 20.50 | 11.14 | 50 | 378745 | 14626 | 50211703 |
Product adhesion issue | 20.45 | 11.14 | 4 | 378791 | 4388 | 50221941 |
Bronchospasm | 20.44 | 11.14 | 51 | 378744 | 14803 | 50211526 |
Motor dysfunction | 20.41 | 11.14 | 18 | 378777 | 8013 | 50218316 |
Peripheral sensory neuropathy | 20.37 | 11.14 | 12 | 378783 | 6579 | 50219750 |
Sneezing | 20.29 | 11.14 | 47 | 378748 | 13997 | 50212332 |
Hepatotoxicity | 20.20 | 11.14 | 301 | 378494 | 26925 | 50199404 |
Head discomfort | 20.19 | 11.14 | 32 | 378763 | 10987 | 50215342 |
Neutrophil count increased | 20.12 | 11.14 | 48 | 378747 | 14147 | 50212182 |
Therapy interrupted | 20.11 | 11.14 | 80 | 378715 | 20072 | 50206257 |
Juvenile idiopathic arthritis | 19.99 | 11.14 | 57 | 378738 | 2822 | 50223507 |
Somnambulism | 19.97 | 11.14 | 6 | 378789 | 4918 | 50221411 |
Hypercapnia | 19.96 | 11.14 | 5 | 378790 | 4622 | 50221707 |
Peritonitis | 19.92 | 11.14 | 55 | 378740 | 15431 | 50210898 |
Salt craving | 19.84 | 11.14 | 11 | 378784 | 84 | 50226245 |
Ischaemia | 19.83 | 11.14 | 4 | 378791 | 4293 | 50222036 |
Dyslipidaemia | 19.82 | 11.14 | 10 | 378785 | 5978 | 50220351 |
Bronchopleural fistula | 19.73 | 11.14 | 15 | 378780 | 206 | 50226123 |
Bradykinesia | 19.66 | 11.14 | 3 | 378792 | 3940 | 50222389 |
Extradural abscess | 19.55 | 11.14 | 27 | 378768 | 777 | 50225552 |
Limb deformity | 19.53 | 11.14 | 67 | 378728 | 3667 | 50222662 |
Spinal fracture | 19.52 | 11.14 | 56 | 378739 | 15517 | 50210812 |
Butterfly rash | 19.51 | 11.14 | 34 | 378761 | 1202 | 50225127 |
Cardiomegaly | 19.50 | 11.14 | 58 | 378737 | 15887 | 50210442 |
Skin toxicity | 19.46 | 11.14 | 3 | 378792 | 3910 | 50222419 |
Drug effective for unapproved indication | 19.36 | 11.14 | 45 | 378750 | 1964 | 50224365 |
Menstruation irregular | 19.36 | 11.14 | 11 | 378784 | 6151 | 50220178 |
Adrenal insufficiency | 19.35 | 11.14 | 177 | 378618 | 14066 | 50212263 |
Blood urine present | 19.32 | 11.14 | 42 | 378753 | 12791 | 50213538 |
Respiration abnormal | 19.32 | 11.14 | 7 | 378788 | 5095 | 50221234 |
Fungal infection | 19.28 | 11.14 | 138 | 378657 | 29827 | 50196502 |
Post transplant lymphoproliferative disorder | 19.22 | 11.14 | 4 | 378791 | 4200 | 50222129 |
Lung infiltration | 19.21 | 11.14 | 45 | 378750 | 13348 | 50212981 |
Diffuse alopecia | 19.18 | 11.14 | 23 | 378772 | 573 | 50225756 |
Wound infection | 19.14 | 11.14 | 156 | 378639 | 11992 | 50214337 |
Functional gastrointestinal disorder | 19.10 | 11.14 | 63 | 378732 | 3379 | 50222950 |
Dermatitis contact | 18.98 | 11.14 | 22 | 378773 | 8624 | 50217705 |
Infective tenosynovitis | 18.91 | 11.14 | 15 | 378780 | 220 | 50226109 |
Lung disorder | 18.90 | 11.14 | 454 | 378341 | 44345 | 50181984 |
Sensory loss | 18.89 | 11.14 | 18 | 378777 | 7720 | 50218609 |
Myocarditis | 18.80 | 11.14 | 19 | 378776 | 7928 | 50218401 |
Aplasia | 18.78 | 11.14 | 3 | 378792 | 3810 | 50222519 |
Metabolic disorder | 18.78 | 11.14 | 8 | 378787 | 5278 | 50221051 |
Hepatic enzyme abnormal | 18.74 | 11.14 | 79 | 378716 | 4770 | 50221559 |
Application site pain | 18.68 | 11.14 | 3 | 378792 | 3795 | 50222534 |
Immune thrombocytopenia | 18.68 | 11.14 | 24 | 378771 | 8993 | 50217336 |
Neuralgia | 18.67 | 11.14 | 92 | 378703 | 21771 | 50204558 |
Blood loss anaemia | 18.65 | 11.14 | 20 | 378775 | 8119 | 50218210 |
Respiratory acidosis | 18.60 | 11.14 | 11 | 378784 | 6017 | 50220312 |
Hallucinations, mixed | 18.56 | 11.14 | 4 | 378791 | 4099 | 50222230 |
Haemolysis | 18.53 | 11.14 | 11 | 378784 | 6005 | 50220324 |
Granulocytopenia | 18.45 | 11.14 | 8 | 378787 | 5223 | 50221106 |
Hyperuricaemia | 18.45 | 11.14 | 6 | 378789 | 4674 | 50221655 |
Blood pressure inadequately controlled | 18.38 | 11.14 | 5 | 378790 | 4375 | 50221954 |
Tinnitus | 18.37 | 11.14 | 129 | 378666 | 28003 | 50198326 |
Palmoplantar pustulosis | 18.36 | 11.14 | 19 | 378776 | 400 | 50225929 |
Antinuclear antibody positive | 18.21 | 11.14 | 94 | 378701 | 6178 | 50220151 |
Hypovolaemic shock | 18.20 | 11.14 | 8 | 378787 | 5180 | 50221149 |
West Nile viral infection | 18.10 | 11.14 | 18 | 378777 | 361 | 50225968 |
Infected seroma | 18.07 | 11.14 | 10 | 378785 | 76 | 50226253 |
Middle lobe syndrome | 18.03 | 11.14 | 8 | 378787 | 35 | 50226294 |
Cerebral atrophy | 17.96 | 11.14 | 6 | 378789 | 4595 | 50221734 |
Hepatic lesion | 17.94 | 11.14 | 4 | 378791 | 4004 | 50222325 |
Partial seizures | 17.87 | 11.14 | 7 | 378788 | 4858 | 50221471 |
Product residue present | 17.84 | 11.14 | 3 | 378792 | 3669 | 50222660 |
Heart rate abnormal | 17.84 | 11.14 | 4 | 378791 | 3988 | 50222341 |
Cholangitis | 17.82 | 11.14 | 6 | 378789 | 4573 | 50221756 |
Expired product administered | 17.80 | 11.14 | 9 | 378786 | 5373 | 50220956 |
Initial insomnia | 17.76 | 11.14 | 8 | 378787 | 5107 | 50221222 |
Respiratory syncytial virus infection | 17.69 | 11.14 | 8 | 378787 | 5094 | 50221235 |
Gallbladder disorder | 17.65 | 11.14 | 65 | 378730 | 16677 | 50209652 |
Atrial septal defect | 17.63 | 11.14 | 13 | 378782 | 6328 | 50220001 |
Hyperthermia | 17.53 | 11.14 | 19 | 378776 | 7677 | 50218652 |
Duodenal ulcer | 17.44 | 11.14 | 15 | 378780 | 6760 | 50219569 |
Incoherent | 17.44 | 11.14 | 5 | 378790 | 4225 | 50222104 |
Androgenetic alopecia | 17.41 | 11.14 | 12 | 378783 | 140 | 50226189 |
Tenosynovitis stenosans | 17.40 | 11.14 | 46 | 378749 | 2178 | 50224151 |
Spinal meningioma benign | 17.37 | 11.14 | 11 | 378784 | 110 | 50226219 |
Nystagmus | 17.37 | 11.14 | 10 | 378785 | 5551 | 50220778 |
Hypomania | 17.36 | 11.14 | 6 | 378789 | 4499 | 50221830 |
Lyme disease | 17.32 | 11.14 | 50 | 378745 | 2493 | 50223836 |
Ketoacidosis | 17.21 | 11.14 | 4 | 378791 | 3891 | 50222438 |
Larynx irritation | 17.13 | 11.14 | 11 | 378784 | 113 | 50226216 |
Micturition urgency | 17.12 | 11.14 | 22 | 378773 | 8242 | 50218087 |
Gastroenteritis | 17.11 | 11.14 | 103 | 378692 | 23178 | 50203151 |
Symptom masked | 17.07 | 11.14 | 23 | 378772 | 646 | 50225683 |
Visual field defect | 17.05 | 11.14 | 87 | 378708 | 5692 | 50220637 |
Cryptococcal meningoencephalitis | 17.00 | 11.14 | 9 | 378786 | 62 | 50226267 |
Toxic epidermal necrolysis | 16.98 | 11.14 | 90 | 378705 | 20902 | 50205427 |
Ocular hyperaemia | 16.98 | 11.14 | 86 | 378709 | 20206 | 50206123 |
Antiphospholipid syndrome | 16.89 | 11.14 | 36 | 378759 | 1481 | 50224848 |
Therapy change | 16.89 | 11.14 | 9 | 378786 | 5216 | 50221113 |
Internal haemorrhage | 16.82 | 11.14 | 6 | 378789 | 4411 | 50221918 |
Pleuritic pain | 16.80 | 11.14 | 94 | 378701 | 6372 | 50219957 |
Eyelid ptosis | 16.80 | 11.14 | 13 | 378782 | 6174 | 50220155 |
Serum ferritin increased | 16.76 | 11.14 | 9 | 378786 | 5193 | 50221136 |
Cutaneous lupus erythematosus | 16.76 | 11.14 | 48 | 378747 | 2383 | 50223946 |
Neoplasm malignant | 16.75 | 11.14 | 260 | 378535 | 23455 | 50202874 |
Peritonitis bacterial | 16.65 | 11.14 | 7 | 378788 | 4654 | 50221675 |
Affect lability | 16.61 | 11.14 | 26 | 378769 | 8972 | 50217357 |
Cranial nerve injury | 16.60 | 11.14 | 6 | 378789 | 13 | 50226316 |
Product preparation error | 16.55 | 11.14 | 6 | 378789 | 4366 | 50221963 |
Retinal deposits | 16.53 | 11.14 | 9 | 378786 | 66 | 50226263 |
Electrocardiogram ST segment elevation | 16.52 | 11.14 | 3 | 378792 | 3470 | 50222859 |
Productive cough | 16.51 | 11.14 | 286 | 378509 | 52408 | 50173921 |
Nasal congestion | 16.49 | 11.14 | 276 | 378519 | 50844 | 50175485 |
Natural killer-cell leukaemia | 16.49 | 11.14 | 10 | 378785 | 92 | 50226237 |
Facial paralysis | 16.47 | 11.14 | 45 | 378750 | 12670 | 50213659 |
Injection site haemorrhage | 16.46 | 11.14 | 93 | 378702 | 21253 | 50205076 |
Septic shock | 16.45 | 11.14 | 315 | 378480 | 56860 | 50169469 |
Brain neoplasm | 16.43 | 11.14 | 4 | 378791 | 3769 | 50222560 |
Epigastric discomfort | 16.37 | 11.14 | 87 | 378708 | 5783 | 50220546 |
Skin reaction | 16.35 | 11.14 | 145 | 378650 | 11423 | 50214906 |
Application site pruritus | 16.34 | 11.14 | 4 | 378791 | 3755 | 50222574 |
Wrong product administered | 16.23 | 11.14 | 10 | 378785 | 5350 | 50220979 |
Eosinophilia | 16.21 | 11.14 | 78 | 378717 | 18574 | 50207755 |
Dermatomyositis | 16.21 | 11.14 | 44 | 378751 | 2117 | 50224212 |
Intestinal ischaemia | 16.17 | 11.14 | 16 | 378779 | 6741 | 50219588 |
Incorrect dosage administered | 16.09 | 11.14 | 38 | 378757 | 1676 | 50224653 |
Apnoea | 16.09 | 11.14 | 17 | 378778 | 6949 | 50219380 |
Anaphylactoid reaction | 16.08 | 11.14 | 3 | 378792 | 3403 | 50222926 |
Drug screen positive | 16.05 | 11.14 | 3 | 378792 | 3399 | 50222930 |
Hypokinesia | 16.01 | 11.14 | 43 | 378752 | 12174 | 50214155 |
Nephropathy toxic | 15.99 | 11.14 | 22 | 378773 | 8007 | 50218322 |
Autoimmune haemolytic anaemia | 15.99 | 11.14 | 5 | 378790 | 3994 | 50222335 |
Fibrin D dimer increased | 15.94 | 11.14 | 6 | 378789 | 4266 | 50222063 |
Clostridial infection | 15.93 | 11.14 | 5 | 378790 | 3985 | 50222344 |
Weight fluctuation | 15.90 | 11.14 | 18 | 378777 | 7130 | 50219199 |
Gingival pain | 15.83 | 11.14 | 13 | 378782 | 5993 | 50220336 |
Device failure | 15.81 | 11.14 | 11 | 378784 | 5517 | 50220812 |
Hypergammaglobulinaemia | 15.70 | 11.14 | 18 | 378777 | 427 | 50225902 |
Viral infection | 15.67 | 11.14 | 146 | 378649 | 29840 | 50196489 |
Mycobacterial infection | 15.66 | 11.14 | 36 | 378759 | 1560 | 50224769 |
Obsessive-compulsive disorder | 15.64 | 11.14 | 3 | 378792 | 3337 | 50222992 |
Gastric ulcer haemorrhage | 15.59 | 11.14 | 7 | 378788 | 4477 | 50221852 |
Cytopenia | 15.59 | 11.14 | 26 | 378769 | 8749 | 50217580 |
Skin irritation | 15.57 | 11.14 | 21 | 378774 | 7706 | 50218623 |
Gonorrhoea | 15.55 | 11.14 | 10 | 378785 | 103 | 50226226 |
Atelectasis | 15.53 | 11.14 | 77 | 378718 | 18193 | 50208136 |
Anticoagulation drug level increased | 15.53 | 11.14 | 12 | 378783 | 169 | 50226160 |
Food allergy | 15.51 | 11.14 | 23 | 378772 | 8114 | 50218215 |
Bacterial test positive | 15.47 | 11.14 | 8 | 378787 | 4715 | 50221614 |
Atrioventricular block second degree | 15.45 | 11.14 | 4 | 378791 | 3617 | 50222712 |
Cerebellar syndrome | 15.45 | 11.14 | 3 | 378792 | 3308 | 50223021 |
Anterior chamber cleavage syndrome | 15.36 | 11.14 | 12 | 378783 | 172 | 50226157 |
Contraindication to medical treatment | 15.34 | 11.14 | 21 | 378774 | 599 | 50225730 |
Blood thyroid stimulating hormone decreased | 15.33 | 11.14 | 6 | 378789 | 4166 | 50222163 |
Left ventricular dysfunction | 15.31 | 11.14 | 35 | 378760 | 10471 | 50215858 |
Cerebral ischaemia | 15.31 | 11.14 | 13 | 378782 | 5895 | 50220434 |
Granulomatous dermatitis | 15.31 | 11.14 | 10 | 378785 | 106 | 50226223 |
Rash papular | 15.31 | 11.14 | 46 | 378749 | 12558 | 50213771 |
Amylase increased | 15.27 | 11.14 | 11 | 378784 | 5419 | 50220910 |
Peripheral coldness | 15.19 | 11.14 | 34 | 378761 | 10249 | 50216080 |
Haemolytic anaemia | 15.19 | 11.14 | 29 | 378766 | 9263 | 50217066 |
Lung neoplasm malignant | 15.12 | 11.14 | 62 | 378733 | 15422 | 50210907 |
Macular degeneration | 15.08 | 11.14 | 56 | 378739 | 14332 | 50211997 |
Cardiac failure acute | 15.07 | 11.14 | 24 | 378771 | 8226 | 50218103 |
Posterior reversible encephalopathy syndrome | 15.06 | 11.14 | 59 | 378736 | 14869 | 50211460 |
Premature delivery | 15.06 | 11.14 | 255 | 378540 | 23408 | 50202921 |
Hypoxic-ischaemic encephalopathy | 15.01 | 11.14 | 5 | 378790 | 3837 | 50222492 |
Osteopenia | 15.00 | 11.14 | 194 | 378601 | 16824 | 50209505 |
Ovarian cyst | 14.98 | 11.14 | 54 | 378741 | 13942 | 50212387 |
Exercise tolerance decreased | 14.89 | 11.14 | 9 | 378786 | 4865 | 50221464 |
Neck surgery | 14.85 | 11.14 | 34 | 378761 | 1469 | 50224860 |
Faeces soft | 14.80 | 11.14 | 6 | 378789 | 4078 | 50222251 |
Fracture delayed union | 14.79 | 11.14 | 44 | 378751 | 2232 | 50224097 |
Atrioventricular block | 14.75 | 11.14 | 16 | 378779 | 6462 | 50219867 |
Adenoiditis | 14.73 | 11.14 | 7 | 378788 | 37 | 50226292 |
Depressive symptom | 14.72 | 11.14 | 3 | 378792 | 3197 | 50223132 |
Eructation | 14.71 | 11.14 | 19 | 378776 | 7102 | 50219227 |
Restless legs syndrome | 14.69 | 11.14 | 65 | 378730 | 15832 | 50210497 |
Rib fracture | 14.68 | 11.14 | 84 | 378711 | 19137 | 50207192 |
Extra dose administered | 14.65 | 11.14 | 10 | 378785 | 5066 | 50221263 |
Retinal haemorrhage | 14.65 | 11.14 | 8 | 378787 | 4573 | 50221756 |
Pneumonia fungal | 14.63 | 11.14 | 7 | 378788 | 4313 | 50222016 |
Diaphragm muscle weakness | 14.55 | 11.14 | 6 | 378789 | 21 | 50226308 |
Insomnia | 14.55 | 11.14 | 1119 | 377676 | 173746 | 50052583 |
Coronary artery stenosis | 14.44 | 11.14 | 7 | 378788 | 4282 | 50222047 |
Unevaluable event | 14.44 | 11.14 | 250 | 378545 | 45816 | 50180513 |
Toxic skin eruption | 14.44 | 11.14 | 40 | 378755 | 11211 | 50215118 |
Creatinine urine abnormal | 14.43 | 11.14 | 7 | 378788 | 39 | 50226290 |
Placenta accreta | 14.42 | 11.14 | 12 | 378783 | 189 | 50226140 |
Pleuropericarditis | 14.39 | 11.14 | 13 | 378782 | 230 | 50226099 |
Uterine leiomyoma | 14.38 | 11.14 | 23 | 378772 | 7868 | 50218461 |
Abortion incomplete | 14.24 | 11.14 | 3 | 378792 | 3123 | 50223206 |
Fluid intake reduced | 14.21 | 11.14 | 3 | 378792 | 3119 | 50223210 |
Nocardiosis | 14.19 | 11.14 | 36 | 378759 | 1662 | 50224667 |
Pruritus allergic | 14.15 | 11.14 | 28 | 378767 | 1092 | 50225237 |
Respiratory rate decreased | 14.12 | 11.14 | 3 | 378792 | 3105 | 50223224 |
Humerus fracture | 14.07 | 11.14 | 22 | 378773 | 7596 | 50218733 |
Drug tolerance | 14.05 | 11.14 | 74 | 378721 | 4902 | 50221427 |
Monocyte count increased | 14.05 | 11.14 | 80 | 378715 | 5459 | 50220870 |
Generalised oedema | 14.03 | 11.14 | 54 | 378741 | 13677 | 50212652 |
Ocular sarcoidosis | 14.01 | 11.14 | 7 | 378788 | 42 | 50226287 |
Venous thrombosis | 13.99 | 11.14 | 8 | 378787 | 4458 | 50221871 |
Drooling | 13.95 | 11.14 | 4 | 378791 | 3380 | 50222949 |
Exposure to toxic agent | 13.88 | 11.14 | 5 | 378790 | 3653 | 50222676 |
Gastric disorder | 13.88 | 11.14 | 304 | 378491 | 29244 | 50197085 |
Gangrene | 13.87 | 11.14 | 9 | 378786 | 4683 | 50221646 |
Tricuspid valve incompetence | 13.85 | 11.14 | 49 | 378746 | 12721 | 50213608 |
Multiple system atrophy | 13.77 | 11.14 | 12 | 378783 | 202 | 50226127 |
Congenital osteodystrophy | 13.75 | 11.14 | 6 | 378789 | 25 | 50226304 |
Angina unstable | 13.74 | 11.14 | 18 | 378777 | 6688 | 50219641 |
Breast pain | 13.73 | 11.14 | 22 | 378773 | 7522 | 50218807 |
Neuropsychiatric lupus | 13.72 | 11.14 | 11 | 378784 | 164 | 50226165 |
Dermatitis exfoliative | 13.71 | 11.14 | 11 | 378784 | 5131 | 50221198 |
Antinuclear antibody negative | 13.67 | 11.14 | 12 | 378783 | 204 | 50226125 |
Gastritis erosive | 13.67 | 11.14 | 11 | 378784 | 5123 | 50221206 |
Normochromic normocytic anaemia | 13.61 | 11.14 | 7 | 378788 | 4139 | 50222190 |
Red blood cell count decreased | 13.58 | 11.14 | 175 | 378620 | 33660 | 50192669 |
Vitamin D deficiency | 13.57 | 11.14 | 42 | 378753 | 11360 | 50214969 |
Rheumatoid factor | 13.52 | 11.14 | 8 | 378787 | 70 | 50226259 |
Gastrointestinal toxicity | 13.51 | 11.14 | 70 | 378725 | 4607 | 50221722 |
Monocyte count abnormal | 13.50 | 11.14 | 11 | 378784 | 168 | 50226161 |
Intervertebral disc compression | 13.49 | 11.14 | 25 | 378770 | 928 | 50225401 |
Blindness | 13.44 | 11.14 | 75 | 378720 | 17194 | 50209135 |
Bursitis infective | 13.42 | 11.14 | 29 | 378766 | 1205 | 50225124 |
Urticarial vasculitis | 13.42 | 11.14 | 19 | 378776 | 560 | 50225769 |
Iodine allergy | 13.37 | 11.14 | 21 | 378774 | 680 | 50225649 |
Petit mal epilepsy | 13.35 | 11.14 | 4 | 378791 | 3285 | 50223044 |
Urine analysis abnormal | 13.33 | 11.14 | 8 | 378787 | 4342 | 50221987 |
Retinogram abnormal | 13.29 | 11.14 | 10 | 378785 | 135 | 50226194 |
Gastric ulcer | 13.28 | 11.14 | 99 | 378696 | 21206 | 50205123 |
Urosepsis | 13.25 | 11.14 | 65 | 378730 | 15400 | 50210929 |
Refusal of treatment by patient | 13.24 | 11.14 | 11 | 378784 | 5042 | 50221287 |
Decubitus ulcer | 13.22 | 11.14 | 32 | 378763 | 9386 | 50216943 |
Systemic inflammatory response syndrome | 13.22 | 11.14 | 11 | 378784 | 5038 | 50221291 |
Spinal cord infection | 13.21 | 11.14 | 19 | 378776 | 568 | 50225761 |
Ovarian granulosa cell tumour | 13.20 | 11.14 | 5 | 378790 | 13 | 50226316 |
Potentiating drug interaction | 13.20 | 11.14 | 6 | 378789 | 3810 | 50222519 |
Oropharyngeal pain | 13.19 | 11.14 | 463 | 378332 | 77338 | 50148991 |
Muscle haemorrhage | 13.15 | 11.14 | 3 | 378792 | 2955 | 50223374 |
Allergy to vaccine | 13.13 | 11.14 | 11 | 378784 | 175 | 50226154 |
Rhinitis allergic | 13.10 | 11.14 | 21 | 378774 | 7179 | 50219150 |
Post-traumatic stress disorder | 13.07 | 11.14 | 8 | 378787 | 4295 | 50222034 |
Vaginal discharge | 13.01 | 11.14 | 12 | 378783 | 5228 | 50221101 |
Non-small cell lung cancer | 13.01 | 11.14 | 3 | 378792 | 2934 | 50223395 |
Lupus enteritis | 13.01 | 11.14 | 7 | 378788 | 50 | 50226279 |
Catheterisation cardiac | 13.00 | 11.14 | 7 | 378788 | 4033 | 50222296 |
Dermatitis bullous | 12.98 | 11.14 | 21 | 378774 | 7152 | 50219177 |
Oral lichen planus | 12.98 | 11.14 | 18 | 378777 | 520 | 50225809 |
Bipolar disorder | 12.98 | 11.14 | 19 | 378776 | 6738 | 50219591 |
Brain natriuretic peptide increased | 12.96 | 11.14 | 9 | 378786 | 4518 | 50221811 |
Atrial flutter | 12.93 | 11.14 | 29 | 378766 | 8734 | 50217595 |
Foetal movement disorder | 12.87 | 11.14 | 4 | 378791 | 4 | 50226325 |
Cerebral haematoma | 12.86 | 11.14 | 4 | 378791 | 3207 | 50223122 |
Dry eye | 12.86 | 11.14 | 323 | 378472 | 31772 | 50194557 |
Intrauterine infection | 12.85 | 11.14 | 9 | 378786 | 108 | 50226221 |
Treatment noncompliance | 12.83 | 11.14 | 154 | 378641 | 29996 | 50196333 |
Performance status decreased | 12.76 | 11.14 | 4 | 378791 | 3191 | 50223138 |
Affective disorder | 12.71 | 11.14 | 12 | 378783 | 5169 | 50221160 |
Erythematotelangiectatic rosacea | 12.69 | 11.14 | 5 | 378790 | 15 | 50226314 |
Hyperinsulinaemic hypoglycaemia | 12.67 | 11.14 | 7 | 378788 | 53 | 50226276 |
Pneumonia bacterial | 12.67 | 11.14 | 22 | 378773 | 7287 | 50219042 |
Urine leukocyte esterase positive | 12.66 | 11.14 | 3 | 378792 | 2880 | 50223449 |
Cytomegalovirus viraemia | 12.65 | 11.14 | 10 | 378785 | 4699 | 50221630 |
Pre-existing condition improved | 12.64 | 11.14 | 21 | 378774 | 7076 | 50219253 |
Coronary artery occlusion | 12.63 | 11.14 | 23 | 378772 | 7480 | 50218849 |
Colon cancer | 12.63 | 11.14 | 29 | 378766 | 8662 | 50217667 |
Culture urine positive | 12.62 | 11.14 | 5 | 378790 | 3446 | 50222883 |
Blood glucose abnormal | 12.58 | 11.14 | 19 | 378776 | 6653 | 50219676 |
Haematocrit decreased | 12.57 | 11.14 | 185 | 378610 | 34791 | 50191538 |
Heparin-induced thrombocytopenia | 12.57 | 11.14 | 7 | 378788 | 3958 | 50222371 |
C-reactive protein decreased | 12.56 | 11.14 | 22 | 378773 | 781 | 50225548 |
Stent placement | 12.54 | 11.14 | 5 | 378790 | 3433 | 50222896 |
Gastrointestinal infection | 12.53 | 11.14 | 21 | 378774 | 7053 | 50219276 |
Eye irritation | 12.51 | 11.14 | 76 | 378719 | 17064 | 50209265 |
Facial paresis | 12.50 | 11.14 | 4 | 378791 | 3148 | 50223181 |
Mitral valve incompetence | 12.47 | 11.14 | 78 | 378717 | 17393 | 50208936 |
Overwork | 12.46 | 11.14 | 7 | 378788 | 55 | 50226274 |
Parosmia | 12.46 | 11.14 | 9 | 378786 | 4427 | 50221902 |
Acute vestibular syndrome | 12.46 | 11.14 | 5 | 378790 | 16 | 50226313 |
Coombs positive haemolytic anaemia | 12.45 | 11.14 | 14 | 378781 | 325 | 50226004 |
Hepatitis | 12.45 | 11.14 | 316 | 378479 | 31137 | 50195192 |
Root canal infection | 12.42 | 11.14 | 12 | 378783 | 232 | 50226097 |
Blood creatine increased | 12.36 | 11.14 | 11 | 378784 | 4876 | 50221453 |
Atrioventricular block first degree | 12.34 | 11.14 | 17 | 378778 | 6184 | 50220145 |
Metastases to peritoneum | 12.34 | 11.14 | 3 | 378792 | 2830 | 50223499 |
Portal hypertension | 12.27 | 11.14 | 5 | 378790 | 3387 | 50222942 |
Localised oedema | 12.26 | 11.14 | 11 | 378784 | 4856 | 50221473 |
Vitamin D decreased | 12.25 | 11.14 | 28 | 378767 | 8378 | 50217951 |
Forced expiratory volume decreased | 12.23 | 11.14 | 9 | 378786 | 4385 | 50221944 |
Cataract | 12.22 | 11.14 | 451 | 378344 | 46849 | 50179480 |
Paradoxical drug reaction | 12.21 | 11.14 | 6 | 378789 | 3641 | 50222688 |
Formication | 12.20 | 11.14 | 6 | 378789 | 3640 | 50222689 |
Cardiopulmonary failure | 12.15 | 11.14 | 5 | 378790 | 3368 | 50222961 |
Inflammatory marker increased | 12.14 | 11.14 | 78 | 378717 | 5556 | 50220773 |
Exposed bone in jaw | 12.13 | 11.14 | 3 | 378792 | 2797 | 50223532 |
Infusion site swelling | 12.08 | 11.14 | 22 | 378773 | 7154 | 50219175 |
Nerve injury | 12.02 | 11.14 | 28 | 378767 | 8322 | 50218007 |
Disease complication | 12.01 | 11.14 | 3 | 378792 | 2779 | 50223550 |
DNA antibody | 12.01 | 11.14 | 6 | 378789 | 36 | 50226293 |
Areflexia | 12.00 | 11.14 | 3 | 378792 | 2777 | 50223552 |
White blood cells urine positive | 11.95 | 11.14 | 10 | 378785 | 4568 | 50221761 |
Hepatitis cholestatic | 11.95 | 11.14 | 17 | 378778 | 6100 | 50220229 |
Pathogen resistance | 11.93 | 11.14 | 15 | 378780 | 5674 | 50220655 |
Anaphylactic shock | 11.93 | 11.14 | 95 | 378700 | 20060 | 50206269 |
Autoimmune hepatitis | 11.83 | 11.14 | 24 | 378771 | 7495 | 50218834 |
Lip ulceration | 11.83 | 11.14 | 35 | 378760 | 1770 | 50224559 |
Blood uric acid increased | 11.82 | 11.14 | 7 | 378788 | 3827 | 50222502 |
Multiple-drug resistance | 11.80 | 11.14 | 5 | 378790 | 3309 | 50223020 |
Thoracic vertebral fracture | 11.79 | 11.14 | 8 | 378787 | 4065 | 50222264 |
Hereditary angioedema | 11.78 | 11.14 | 14 | 378781 | 5428 | 50220901 |
Varicose vein | 11.72 | 11.14 | 9 | 378786 | 4291 | 50222038 |
Mycobacterium marinum infection | 11.71 | 11.14 | 11 | 378784 | 205 | 50226124 |
Central nervous system lupus | 11.69 | 11.14 | 13 | 378782 | 298 | 50226031 |
Gastric cancer | 11.67 | 11.14 | 4 | 378791 | 3014 | 50223315 |
Eczema | 11.67 | 11.14 | 111 | 378684 | 22591 | 50203738 |
Infection reactivation | 11.67 | 11.14 | 24 | 378771 | 963 | 50225366 |
Occult blood positive | 11.66 | 11.14 | 5 | 378790 | 3286 | 50223043 |
Smear cervix abnormal | 11.66 | 11.14 | 46 | 378749 | 2695 | 50223634 |
Catheter site infection | 11.64 | 11.14 | 9 | 378786 | 4277 | 50222052 |
Culture tissue specimen positive | 11.62 | 11.14 | 4 | 378791 | 7 | 50226322 |
Peripheral ischaemia | 11.59 | 11.14 | 9 | 378786 | 4267 | 50222062 |
Anticipatory anxiety | 11.55 | 11.14 | 13 | 378782 | 302 | 50226027 |
C-reactive protein | 11.55 | 11.14 | 22 | 378773 | 834 | 50225495 |
Urine abnormality | 11.54 | 11.14 | 18 | 378777 | 6220 | 50220109 |
Transaminases increased | 11.51 | 11.14 | 143 | 378652 | 27681 | 50198648 |
Mood swings | 11.51 | 11.14 | 71 | 378724 | 15883 | 50210446 |
Obesity | 11.50 | 11.14 | 183 | 378612 | 16592 | 50209737 |
Aortic arteriosclerosis | 11.49 | 11.14 | 14 | 378781 | 5368 | 50220961 |
Injection site swelling | 11.45 | 11.14 | 232 | 378563 | 41541 | 50184788 |
Blood lactic acid increased | 11.43 | 11.14 | 15 | 378780 | 5570 | 50220759 |
Papulopustular rosacea | 11.43 | 11.14 | 5 | 378790 | 21 | 50226308 |
Injection site induration | 11.42 | 11.14 | 29 | 378766 | 8368 | 50217961 |
Screaming | 11.42 | 11.14 | 4 | 378791 | 2974 | 50223355 |
Decreased interest | 11.41 | 11.14 | 4 | 378791 | 2972 | 50223357 |
Thyroid disorder | 11.38 | 11.14 | 145 | 378650 | 12532 | 50213797 |
Transient hypogammaglobulinaemia of infancy | 11.37 | 11.14 | 6 | 378789 | 41 | 50226288 |
Electrocardiogram abnormal | 11.36 | 11.14 | 25 | 378770 | 7580 | 50218749 |
Intervertebral disc space narrowing | 11.33 | 11.14 | 23 | 378772 | 914 | 50225415 |
Kidney transplant rejection | 11.31 | 11.14 | 8 | 378787 | 3979 | 50222350 |
Ganglioneuroma | 11.29 | 11.14 | 9 | 378786 | 133 | 50226196 |
Scleritis | 11.27 | 11.14 | 51 | 378744 | 3176 | 50223153 |
Blepharospasm | 11.24 | 11.14 | 4 | 378791 | 2944 | 50223385 |
Vaginal haematoma | 11.23 | 11.14 | 9 | 378786 | 134 | 50226195 |
Tooth loss | 11.23 | 11.14 | 18 | 378777 | 6152 | 50220177 |
Bowel movement irregularity | 11.21 | 11.14 | 8 | 378787 | 3960 | 50222369 |
Endocarditis | 11.21 | 11.14 | 13 | 378782 | 5094 | 50221235 |
Complement factor C3 decreased | 11.20 | 11.14 | 11 | 378784 | 217 | 50226112 |
Photopsia | 11.20 | 11.14 | 8 | 378787 | 3958 | 50222371 |
Herpes zoster cutaneous disseminated | 11.18 | 11.14 | 9 | 378786 | 135 | 50226194 |
Staphylococcal bacteraemia | 11.16 | 11.14 | 12 | 378783 | 4865 | 50221464 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Off label use | 3990.46 | 13.39 | 3934 | 58045 | 296866 | 29215682 |
Drug ineffective | 2022.59 | 13.39 | 3074 | 58905 | 360096 | 29152452 |
Rheumatoid arthritis | 1410.22 | 13.39 | 863 | 61116 | 31289 | 29481259 |
Drug intolerance | 1298.66 | 13.39 | 957 | 61022 | 47422 | 29465126 |
Joint swelling | 1175.22 | 13.39 | 911 | 61068 | 48719 | 29463829 |
Synovitis | 982.26 | 13.39 | 472 | 61507 | 10418 | 29502130 |
Contraindicated product administered | 842.94 | 13.39 | 507 | 61472 | 17759 | 29494789 |
Treatment failure | 714.47 | 13.39 | 603 | 61376 | 36336 | 29476212 |
Apparent death | 485.15 | 13.39 | 205 | 61774 | 3299 | 29509249 |
Therapeutic product effect decreased | 438.58 | 13.39 | 415 | 61564 | 29036 | 29483512 |
C-reactive protein abnormal | 432.88 | 13.39 | 230 | 61749 | 6306 | 29506242 |
Arthropathy | 386.11 | 13.39 | 337 | 61642 | 21217 | 29491331 |
Bone erosion | 377.19 | 13.39 | 160 | 61819 | 2600 | 29509948 |
Electrocardiogram QT prolonged | 365.91 | 13.39 | 414 | 61565 | 35723 | 29476825 |
Arthralgia | 348.38 | 13.39 | 847 | 61132 | 138770 | 29373778 |
Diverticulitis | 317.43 | 13.39 | 277 | 61702 | 17427 | 29495121 |
Red blood cell sedimentation rate abnormal | 306.40 | 13.39 | 131 | 61848 | 2172 | 29510376 |
Pain | 305.01 | 13.39 | 918 | 61061 | 170514 | 29342034 |
Death | 296.10 | 13.39 | 176 | 61803 | 341908 | 29170640 |
Red blood cell sedimentation rate increased | 270.78 | 13.39 | 178 | 61801 | 7283 | 29505265 |
Loss of personal independence in daily activities | 270.35 | 13.39 | 299 | 61680 | 25141 | 29487407 |
Musculoskeletal stiffness | 267.42 | 13.39 | 360 | 61619 | 37098 | 29475450 |
Mobility decreased | 236.78 | 13.39 | 281 | 61698 | 25499 | 29487049 |
Long QT syndrome | 203.80 | 13.39 | 98 | 61881 | 2160 | 29510388 |
Condition aggravated | 202.67 | 13.39 | 720 | 61259 | 145575 | 29366973 |
C-reactive protein increased | 201.44 | 13.39 | 345 | 61634 | 43918 | 29468630 |
Febrile neutropenia | 197.26 | 13.39 | 9 | 61970 | 112231 | 29400317 |
Impaired work ability | 191.25 | 13.39 | 129 | 61850 | 5511 | 29507037 |
Sleep disorder due to general medical condition, insomnia type | 191.08 | 13.39 | 79 | 61900 | 1199 | 29511349 |
Hand deformity | 190.90 | 13.39 | 92 | 61887 | 2038 | 29510510 |
Drug hypersensitivity | 180.87 | 13.39 | 425 | 61554 | 67981 | 29444567 |
Rheumatoid factor negative | 175.76 | 13.39 | 66 | 61913 | 764 | 29511784 |
Intentional product use issue | 172.39 | 13.39 | 315 | 61664 | 42183 | 29470365 |
Peripheral swelling | 171.77 | 13.39 | 399 | 61580 | 63340 | 29449208 |
Rheumatoid factor positive | 171.57 | 13.39 | 61 | 61918 | 597 | 29511951 |
Therapeutic product effect incomplete | 162.80 | 13.39 | 294 | 61685 | 39011 | 29473537 |
Hepatitis | 159.42 | 13.39 | 207 | 61772 | 20576 | 29491972 |
Lymphoma | 150.95 | 13.39 | 141 | 61838 | 9687 | 29502861 |
Drug effective for unapproved indication | 149.31 | 13.39 | 69 | 61910 | 1386 | 29511162 |
Knee arthroplasty | 148.81 | 13.39 | 112 | 61867 | 5697 | 29506851 |
Anaemia | 141.39 | 13.39 | 128 | 61851 | 200823 | 29311725 |
Pulmonary thrombosis | 140.90 | 13.39 | 114 | 61865 | 6451 | 29506097 |
Polyarthritis | 135.59 | 13.39 | 91 | 61888 | 3854 | 29508694 |
Product use in unapproved indication | 135.33 | 13.39 | 445 | 61534 | 86430 | 29426118 |
Gastrointestinal disorder | 132.18 | 13.39 | 225 | 61754 | 28481 | 29484067 |
Onychoclasis | 131.24 | 13.39 | 67 | 61912 | 1686 | 29510862 |
Constipation | 128.02 | 13.39 | 40 | 61939 | 114120 | 29398428 |
Drug ineffective for unapproved indication | 124.01 | 13.39 | 151 | 61828 | 14063 | 29498485 |
Dehydration | 122.06 | 13.39 | 44 | 61935 | 114704 | 29397844 |
Herpes zoster | 119.61 | 13.39 | 221 | 61758 | 29831 | 29482717 |
Drug tolerance decreased | 117.19 | 13.39 | 57 | 61922 | 1289 | 29511259 |
Terminal state | 116.27 | 13.39 | 79 | 61900 | 3415 | 29509133 |
Joint stiffness | 115.83 | 13.39 | 120 | 61859 | 9353 | 29503195 |
Osteoarthritis | 115.62 | 13.39 | 165 | 61814 | 17938 | 29494610 |
Arthritis | 112.41 | 13.39 | 194 | 61785 | 24825 | 29487723 |
Malignant neoplasm progression | 112.27 | 13.39 | 12 | 61967 | 73847 | 29438701 |
Hypotension | 110.02 | 13.39 | 148 | 61831 | 194206 | 29318342 |
Limb discomfort | 109.50 | 13.39 | 117 | 61862 | 9451 | 29503097 |
Decreased appetite | 108.96 | 13.39 | 87 | 61892 | 145255 | 29367293 |
Toxicity to various agents | 104.75 | 13.39 | 126 | 61853 | 173535 | 29339013 |
Acne cystic | 103.34 | 13.39 | 39 | 61940 | 458 | 29512090 |
Rheumatoid nodule | 103.21 | 13.39 | 61 | 61918 | 2061 | 29510487 |
Drug specific antibody present | 102.51 | 13.39 | 65 | 61914 | 2496 | 29510052 |
Joint lock | 101.76 | 13.39 | 49 | 61930 | 1083 | 29511465 |
Anti-cyclic citrullinated peptide antibody positive | 100.21 | 13.39 | 44 | 61935 | 780 | 29511768 |
Vomiting | 98.96 | 13.39 | 184 | 61795 | 212076 | 29300472 |
Overdose | 96.84 | 13.39 | 24 | 61955 | 79795 | 29432753 |
Tooth loss | 96.69 | 13.39 | 72 | 61907 | 3602 | 29508946 |
Diarrhoea | 96.24 | 13.39 | 366 | 61613 | 332332 | 29180216 |
Pyrexia | 95.60 | 13.39 | 298 | 61681 | 287324 | 29225224 |
Seizure | 95.18 | 13.39 | 38 | 61941 | 93085 | 29419463 |
Acute kidney injury | 91.59 | 13.39 | 270 | 61709 | 264997 | 29247551 |
Bone cyst | 91.04 | 13.39 | 37 | 61942 | 536 | 29512012 |
Abdominal pain | 90.65 | 13.39 | 90 | 61889 | 135267 | 29377281 |
Confusional state | 84.51 | 13.39 | 86 | 61893 | 127791 | 29384757 |
Mass | 83.22 | 13.39 | 88 | 61891 | 7023 | 29505525 |
Disability | 82.95 | 13.39 | 71 | 61908 | 4345 | 29508203 |
Physical disability | 82.63 | 13.39 | 44 | 61935 | 1210 | 29511338 |
Photosensitivity reaction | 80.17 | 13.39 | 98 | 61881 | 9160 | 29503388 |
X-ray abnormal | 79.86 | 13.39 | 32 | 61947 | 446 | 29512102 |
Systemic lupus erythematosus | 78.28 | 13.39 | 55 | 61924 | 2511 | 29510037 |
Completed suicide | 78.26 | 13.39 | 46 | 61933 | 90200 | 29422348 |
Nodule | 77.83 | 13.39 | 73 | 61906 | 5039 | 29507509 |
Psoriatic arthropathy | 76.84 | 13.39 | 122 | 61857 | 14569 | 29497979 |
Intestinal polyp | 74.64 | 13.39 | 37 | 61942 | 873 | 29511675 |
Drug abuse | 73.20 | 13.39 | 38 | 61941 | 79845 | 29432703 |
Syncope | 72.67 | 13.39 | 40 | 61939 | 81331 | 29431217 |
Cytology abnormal | 71.09 | 13.39 | 28 | 61951 | 372 | 29512176 |
Ill-defined disorder | 70.99 | 13.39 | 104 | 61875 | 11574 | 29500974 |
Drug use disorder | 70.43 | 13.39 | 58 | 61921 | 3364 | 29509184 |
Hip arthroplasty | 69.73 | 13.39 | 60 | 61919 | 3698 | 29508850 |
Joint arthroplasty | 69.18 | 13.39 | 32 | 61947 | 644 | 29511904 |
Fall | 67.27 | 13.39 | 172 | 61807 | 177006 | 29335542 |
Blood glucose increased | 67.27 | 13.39 | 20 | 61959 | 58964 | 29453584 |
Foot deformity | 66.30 | 13.39 | 60 | 61919 | 3955 | 29508593 |
Loss of consciousness | 63.84 | 13.39 | 38 | 61941 | 74018 | 29438530 |
Pulmonary fibrosis | 63.75 | 13.39 | 116 | 61863 | 15466 | 29497082 |
Bladder transitional cell carcinoma | 62.03 | 13.39 | 47 | 61932 | 2414 | 29510134 |
Rhabdomyolysis | 61.80 | 13.39 | 25 | 61954 | 60783 | 29451765 |
Hypertransaminasaemia | 61.74 | 13.39 | 55 | 61924 | 3551 | 29508997 |
Arthritis bacterial | 61.46 | 13.39 | 60 | 61919 | 4353 | 29508195 |
Hyperkalaemia | 61.17 | 13.39 | 26 | 61953 | 61366 | 29451182 |
Alopecia | 60.96 | 13.39 | 128 | 61851 | 18956 | 29493592 |
Neoplasm malignant | 60.57 | 13.39 | 119 | 61860 | 16806 | 29495742 |
COVID-19 treatment | 59.50 | 13.39 | 22 | 61957 | 243 | 29512305 |
Drug dependence | 59.36 | 13.39 | 134 | 61845 | 20847 | 29491701 |
Skin ulcer | 58.60 | 13.39 | 125 | 61854 | 18715 | 29493833 |
Pain in extremity | 58.48 | 13.39 | 414 | 61565 | 110019 | 29402529 |
Platelet count decreased | 57.82 | 13.39 | 81 | 61898 | 104591 | 29407957 |
Musculoskeletal pain | 56.87 | 13.39 | 161 | 61818 | 28792 | 29483756 |
Victim of child abuse | 56.67 | 13.39 | 30 | 61949 | 815 | 29511733 |
Hospitalisation | 55.42 | 13.39 | 14 | 61965 | 45974 | 29466574 |
Dyspnoea | 55.21 | 13.39 | 430 | 61549 | 326302 | 29186246 |
Intestinal sepsis | 55.04 | 13.39 | 24 | 61955 | 418 | 29512130 |
Thrombocytopenia | 54.99 | 13.39 | 126 | 61853 | 134697 | 29377851 |
Urinary tract infection | 54.54 | 13.39 | 43 | 61936 | 72311 | 29440237 |
General physical health deterioration | 54.45 | 13.39 | 82 | 61897 | 102775 | 29409773 |
Grip strength decreased | 53.64 | 13.39 | 42 | 61937 | 2265 | 29510283 |
Inflammation | 52.30 | 13.39 | 134 | 61845 | 22594 | 29489954 |
Blood creatinine increased | 52.01 | 13.39 | 61 | 61918 | 85041 | 29427507 |
Plasma cell myeloma | 51.63 | 13.39 | 8 | 61971 | 37107 | 29475441 |
Coma | 51.59 | 13.39 | 10 | 61969 | 39440 | 29473108 |
Hallucination | 51.27 | 13.39 | 15 | 61964 | 44697 | 29467851 |
Deep vein thrombosis | 51.13 | 13.39 | 247 | 61732 | 57152 | 29455396 |
Premature baby | 50.72 | 13.39 | 112 | 61867 | 17168 | 29495380 |
Blood pressure diastolic abnormal | 49.93 | 13.39 | 42 | 61937 | 2509 | 29510039 |
Neutropenia | 49.07 | 13.39 | 129 | 61850 | 131582 | 29380966 |
No adverse event | 48.74 | 13.39 | 111 | 61868 | 17367 | 29495181 |
Gastric disorder | 48.05 | 13.39 | 83 | 61896 | 10621 | 29501927 |
Dizziness | 47.62 | 13.39 | 220 | 61759 | 189464 | 29323084 |
Soft tissue swelling | 47.52 | 13.39 | 20 | 61959 | 318 | 29512230 |
Epistaxis | 46.75 | 13.39 | 25 | 61954 | 51679 | 29460869 |
Ascites | 46.40 | 13.39 | 10 | 61969 | 36609 | 29475939 |
Gait inability | 46.13 | 13.39 | 112 | 61867 | 18263 | 29494285 |
Seronegative arthritis | 46.09 | 13.39 | 27 | 61952 | 897 | 29511651 |
Skin laceration | 46.07 | 13.39 | 83 | 61896 | 10979 | 29501569 |
Swelling | 45.54 | 13.39 | 170 | 61809 | 35113 | 29477435 |
Liver function test increased | 45.51 | 13.39 | 86 | 61893 | 11799 | 29500749 |
Renal impairment | 44.84 | 13.39 | 63 | 61916 | 81270 | 29431278 |
Prerenal failure | 44.74 | 13.39 | 34 | 61945 | 1754 | 29510794 |
Neutrophil count decreased | 44.12 | 13.39 | 18 | 61961 | 43549 | 29468999 |
Somnolence | 44.06 | 13.39 | 81 | 61898 | 93874 | 29418674 |
Cardiac failure | 43.13 | 13.39 | 62 | 61917 | 79225 | 29433323 |
Lupus nephritis | 42.88 | 13.39 | 17 | 61962 | 230 | 29512318 |
Gastrointestinal haemorrhage | 42.47 | 13.39 | 63 | 61916 | 79470 | 29433078 |
Therapeutic response decreased | 42.41 | 13.39 | 131 | 61848 | 24580 | 29487968 |
Blood pressure systolic abnormal | 41.11 | 13.39 | 35 | 61944 | 2126 | 29510422 |
Skin mass | 40.98 | 13.39 | 43 | 61936 | 3400 | 29509148 |
Oral surgery | 40.86 | 13.39 | 21 | 61958 | 536 | 29512012 |
Immobile | 39.95 | 13.39 | 35 | 61944 | 2210 | 29510338 |
Cardiac arrest | 38.20 | 13.39 | 76 | 61903 | 85515 | 29427033 |
Malaise | 37.76 | 13.39 | 189 | 61790 | 159413 | 29353135 |
C-reactive protein decreased | 37.72 | 13.39 | 29 | 61950 | 1522 | 29511026 |
Pneumonia aspiration | 37.49 | 13.39 | 15 | 61964 | 36722 | 29475826 |
Medical device implantation | 37.39 | 13.39 | 20 | 61959 | 555 | 29511993 |
Hepatic function abnormal | 36.95 | 13.39 | 18 | 61961 | 39241 | 29473307 |
Blood pressure decreased | 36.89 | 13.39 | 25 | 61954 | 45452 | 29467096 |
Limb deformity | 36.75 | 13.39 | 19 | 61960 | 491 | 29512057 |
Hyperglycaemia | 36.66 | 13.39 | 13 | 61966 | 34274 | 29478274 |
Anxiety | 36.23 | 13.39 | 78 | 61901 | 85287 | 29427261 |
Orthostatic hypotension | 36.16 | 13.39 | 3 | 61976 | 22626 | 29489922 |
Disorientation | 35.53 | 13.39 | 9 | 61970 | 29506 | 29483042 |
Pulmonary embolism | 35.40 | 13.39 | 278 | 61701 | 76256 | 29436292 |
Restlessness | 35.21 | 13.39 | 3 | 61976 | 22142 | 29490406 |
Disturbance in attention | 33.80 | 13.39 | 3 | 61976 | 21421 | 29491127 |
Pancytopenia | 33.65 | 13.39 | 78 | 61901 | 83090 | 29429458 |
Unresponsive to stimuli | 33.64 | 13.39 | 6 | 61973 | 25120 | 29487428 |
Fine motor skill dysfunction | 33.42 | 13.39 | 27 | 61952 | 1524 | 29511024 |
Blood urea increased | 33.02 | 13.39 | 9 | 61970 | 28103 | 29484445 |
Infection | 32.90 | 13.39 | 274 | 61705 | 76477 | 29436071 |
Blood pressure fluctuation | 32.79 | 13.39 | 104 | 61875 | 19790 | 29492758 |
International normalised ratio increased | 32.64 | 13.39 | 27 | 61952 | 44345 | 29468203 |
Lymphoedema | 32.59 | 13.39 | 38 | 61941 | 3379 | 29509169 |
Heart block congenital | 32.32 | 13.39 | 9 | 61970 | 35 | 29512513 |
Low birth weight baby | 31.99 | 13.39 | 53 | 61926 | 6555 | 29505993 |
Dysphagia | 31.83 | 13.39 | 41 | 61938 | 54885 | 29457663 |
Abdominal discomfort | 31.67 | 13.39 | 190 | 61789 | 47713 | 29464835 |
Liver injury | 31.47 | 13.39 | 77 | 61902 | 12613 | 29499935 |
Disease progression | 31.43 | 13.39 | 79 | 61900 | 81837 | 29430711 |
Lethargy | 31.37 | 13.39 | 20 | 61959 | 37560 | 29474988 |
Hypoglycaemia | 31.34 | 13.39 | 33 | 61946 | 48313 | 29464235 |
Dactylitis | 31.28 | 13.39 | 19 | 61960 | 675 | 29511873 |
Joint range of motion decreased | 31.27 | 13.39 | 50 | 61929 | 6004 | 29506544 |
Basal cell carcinoma | 31.23 | 13.39 | 92 | 61887 | 16818 | 29495730 |
Dyskinesia | 31.13 | 13.39 | 3 | 61976 | 20058 | 29492490 |
Agitation | 31.09 | 13.39 | 37 | 61942 | 51267 | 29461281 |
Haematuria | 31.08 | 13.39 | 28 | 61951 | 44111 | 29468437 |
Aggression | 30.95 | 13.39 | 18 | 61961 | 35523 | 29477025 |
Herpes simplex viraemia | 30.93 | 13.39 | 10 | 61969 | 71 | 29512477 |
Fatigue | 30.85 | 13.39 | 473 | 61506 | 316348 | 29196200 |
Intentional overdose | 30.17 | 13.39 | 22 | 61957 | 38506 | 29474042 |
Bone marrow failure | 30.05 | 13.39 | 10 | 61969 | 27439 | 29485109 |
Hepatic enzyme increased | 29.76 | 13.39 | 145 | 61834 | 33654 | 29478894 |
Dysarthria | 29.35 | 13.39 | 14 | 61965 | 30897 | 29481651 |
Sensitivity to weather change | 29.10 | 13.39 | 24 | 61955 | 1395 | 29511153 |
Asthenia | 28.91 | 13.39 | 300 | 61679 | 214950 | 29297598 |
Metabolic acidosis | 28.85 | 13.39 | 22 | 61957 | 37640 | 29474908 |
Haematemesis | 28.71 | 13.39 | 8 | 61971 | 24618 | 29487930 |
Chest pain | 28.57 | 13.39 | 129 | 61850 | 111844 | 29400704 |
Medication error | 28.54 | 13.39 | 5 | 61974 | 21206 | 29491342 |
Joint ankylosis | 28.38 | 13.39 | 15 | 61964 | 406 | 29512142 |
Neoplasm progression | 28.32 | 13.39 | 3 | 61976 | 18609 | 29493939 |
Irritability | 28.16 | 13.39 | 6 | 61973 | 22146 | 29490402 |
Abdominal distension | 27.94 | 13.39 | 33 | 61946 | 45878 | 29466670 |
Hyponatraemia | 27.71 | 13.39 | 63 | 61916 | 67570 | 29444978 |
Maculopathy | 27.70 | 13.39 | 19 | 61960 | 834 | 29511714 |
Foetal exposure during pregnancy | 27.49 | 13.39 | 142 | 61837 | 33725 | 29478823 |
White blood cell count increased | 27.38 | 13.39 | 23 | 61956 | 37493 | 29475055 |
Respiratory arrest | 27.26 | 13.39 | 10 | 61969 | 25823 | 29486725 |
Muscle spasms | 27.17 | 13.39 | 60 | 61919 | 65022 | 29447526 |
Cryopyrin associated periodic syndrome | 27.02 | 13.39 | 9 | 61970 | 71 | 29512477 |
Blood bilirubin increased | 27.00 | 13.39 | 19 | 61960 | 33874 | 29478674 |
Cognitive disorder | 26.72 | 13.39 | 8 | 61971 | 23491 | 29489057 |
Interstitial lung disease | 26.32 | 13.39 | 209 | 61770 | 57509 | 29455039 |
Vitamin D deficiency | 26.31 | 13.39 | 44 | 61935 | 5485 | 29507063 |
External auditory canal atresia | 26.25 | 13.39 | 11 | 61968 | 173 | 29512375 |
Flushing | 26.23 | 13.39 | 14 | 61965 | 28978 | 29483570 |
Acute lung injury | 26.20 | 13.39 | 22 | 61957 | 1311 | 29511237 |
Epidural lipomatosis | 25.88 | 13.39 | 17 | 61962 | 694 | 29511854 |
Cerebral haemorrhage | 25.86 | 13.39 | 17 | 61962 | 31409 | 29481139 |
Suicidal ideation | 25.68 | 13.39 | 21 | 61958 | 34695 | 29477853 |
Thrombosis | 25.49 | 13.39 | 166 | 61813 | 42879 | 29469669 |
Juvenile idiopathic arthritis | 25.34 | 13.39 | 22 | 61957 | 1372 | 29511176 |
Pneumonia | 25.05 | 13.39 | 497 | 61482 | 319675 | 29192873 |
Microcephaly | 25.05 | 13.39 | 17 | 61962 | 733 | 29511815 |
Tuberculosis | 25.02 | 13.39 | 50 | 61929 | 7146 | 29505402 |
Product use issue | 24.96 | 13.39 | 189 | 61790 | 51255 | 29461293 |
Cerebrovascular accident | 24.50 | 13.39 | 81 | 61898 | 76830 | 29435718 |
Cytomegalovirus infection | 24.48 | 13.39 | 9 | 61970 | 23206 | 29489342 |
Neck mass | 24.19 | 13.39 | 22 | 61957 | 1459 | 29511089 |
Aspartate aminotransferase increased | 24.16 | 13.39 | 56 | 61923 | 59669 | 29452879 |
Latent tuberculosis | 24.02 | 13.39 | 19 | 61960 | 1040 | 29511508 |
Hypofibrinogenaemia | 23.94 | 13.39 | 22 | 61957 | 1479 | 29511069 |
Hypophagia | 23.93 | 13.39 | 7 | 61972 | 20865 | 29491683 |
Joint effusion | 23.62 | 13.39 | 36 | 61943 | 4148 | 29508400 |
Diffuse idiopathic skeletal hyperostosis | 23.56 | 13.39 | 7 | 61972 | 36 | 29512512 |
Wheezing | 23.50 | 13.39 | 21 | 61958 | 33219 | 29479329 |
Medium-chain acyl-coenzyme A dehydrogenase deficiency | 23.40 | 13.39 | 7 | 61972 | 37 | 29512511 |
Pulmonary toxicity | 23.38 | 13.39 | 39 | 61940 | 4851 | 29507697 |
Cardio-respiratory arrest | 23.37 | 13.39 | 44 | 61935 | 50557 | 29461991 |
Atrial fibrillation | 23.34 | 13.39 | 128 | 61851 | 105518 | 29407030 |
Fragile X syndrome | 23.25 | 13.39 | 7 | 61972 | 38 | 29512510 |
Hepatic enzyme abnormal | 23.18 | 13.39 | 26 | 61953 | 2216 | 29510332 |
Cutaneous lupus erythematosus | 23.13 | 13.39 | 16 | 61963 | 712 | 29511836 |
Incorrect dose administered | 23.12 | 13.39 | 21 | 61958 | 32963 | 29479585 |
Product quality issue | 23.10 | 13.39 | 3 | 61976 | 15892 | 29496656 |
Ocular toxicity | 22.68 | 13.39 | 10 | 61969 | 179 | 29512369 |
Glucose-6-phosphate dehydrogenase deficiency | 22.62 | 13.39 | 9 | 61970 | 123 | 29512425 |
Iris coloboma | 22.50 | 13.39 | 6 | 61973 | 19 | 29512529 |
Encephalitis Japanese B | 22.50 | 13.39 | 6 | 61973 | 19 | 29512529 |
Disease recurrence | 22.50 | 13.39 | 79 | 61900 | 15835 | 29496713 |
Hepatic cirrhosis | 22.43 | 13.39 | 74 | 61905 | 14370 | 29498178 |
Retinal coloboma | 22.26 | 13.39 | 6 | 61973 | 20 | 29512528 |
Vision blurred | 22.25 | 13.39 | 31 | 61948 | 40145 | 29472403 |
Depressed level of consciousness | 22.00 | 13.39 | 27 | 61952 | 36915 | 29475633 |
Osteonecrosis of jaw | 21.98 | 13.39 | 4 | 61975 | 16506 | 29496042 |
Alanine aminotransferase abnormal | 21.96 | 13.39 | 29 | 61950 | 2928 | 29509620 |
Oral disorder | 21.93 | 13.39 | 33 | 61946 | 3760 | 29508788 |
Arthrodesis | 21.84 | 13.39 | 13 | 61966 | 445 | 29512103 |
Infection reactivation | 21.49 | 13.39 | 18 | 61961 | 1069 | 29511479 |
Septic shock | 21.25 | 13.39 | 64 | 61915 | 62496 | 29450052 |
Hypokalaemia | 21.18 | 13.39 | 46 | 61933 | 50157 | 29462391 |
Abnormal behaviour | 21.17 | 13.39 | 11 | 61968 | 23116 | 29489432 |
Intestinal obstruction | 21.14 | 13.39 | 7 | 61972 | 19270 | 29493278 |
Subdural haematoma | 21.04 | 13.39 | 6 | 61973 | 18187 | 29494361 |
Coronavirus infection | 21.03 | 13.39 | 30 | 61949 | 3258 | 29509290 |
Full blood count decreased | 21.02 | 13.39 | 4 | 61975 | 15988 | 29496560 |
Palmar-plantar erythrodysaesthesia syndrome | 20.94 | 13.39 | 3 | 61976 | 14756 | 29497792 |
External ear disorder | 20.85 | 13.39 | 6 | 61973 | 27 | 29512521 |
Coronary artery disease | 20.78 | 13.39 | 38 | 61941 | 44152 | 29468396 |
Acute myocardial infarction | 20.76 | 13.39 | 44 | 61935 | 48394 | 29464154 |
Blood potassium increased | 20.73 | 13.39 | 3 | 61976 | 14648 | 29497900 |
Drug withdrawal syndrome | 20.67 | 13.39 | 6 | 61973 | 17978 | 29494570 |
Trisomy 8 | 20.61 | 13.39 | 7 | 61972 | 59 | 29512489 |
Meningitis noninfective | 20.38 | 13.39 | 5 | 61974 | 10 | 29512538 |
Therapy partial responder | 20.37 | 13.39 | 38 | 61941 | 5161 | 29507387 |
Suicide attempt | 20.24 | 13.39 | 25 | 61954 | 34085 | 29478463 |
PaO2/FiO2 ratio decreased | 20.17 | 13.39 | 6 | 61973 | 31 | 29512517 |
Ossicle disorder | 20.01 | 13.39 | 6 | 61973 | 32 | 29512516 |
Anaphylactic reaction | 20.00 | 13.39 | 17 | 61962 | 27556 | 29484992 |
Stevens-Johnson syndrome | 19.91 | 13.39 | 5 | 61974 | 16492 | 29496056 |
Mycobacterium fortuitum infection | 19.88 | 13.39 | 9 | 61970 | 172 | 29512376 |
Panniculitis | 19.68 | 13.39 | 18 | 61961 | 1203 | 29511345 |
Red blood cell sedimentation rate | 19.57 | 13.39 | 13 | 61966 | 541 | 29512007 |
Cellulitis | 19.34 | 13.39 | 42 | 61937 | 45798 | 29466750 |
Mental status changes | 19.29 | 13.39 | 27 | 61952 | 34900 | 29477648 |
Haemorrhage | 19.26 | 13.39 | 41 | 61938 | 45031 | 29467517 |
Urticaria | 19.24 | 13.39 | 187 | 61792 | 54473 | 29458075 |
Blood pressure systolic increased | 19.15 | 13.39 | 78 | 61901 | 16767 | 29495781 |
Squamous cell carcinoma | 19.15 | 13.39 | 56 | 61923 | 10195 | 29502353 |
Myalgia | 19.03 | 13.39 | 85 | 61894 | 73934 | 29438614 |
Jaundice | 18.98 | 13.39 | 20 | 61959 | 29276 | 29483272 |
Erectile dysfunction | 18.96 | 13.39 | 7 | 61972 | 18002 | 29494546 |
Pneumatosis intestinalis | 18.93 | 13.39 | 28 | 61951 | 3141 | 29509407 |
Acute cutaneous lupus erythematosus | 18.80 | 13.39 | 7 | 61972 | 79 | 29512469 |
Liver function test | 18.63 | 13.39 | 6 | 61973 | 42 | 29512506 |
Maternal exposure during pregnancy | 18.54 | 13.39 | 32 | 61947 | 4091 | 29508457 |
Antinuclear antibody positive | 18.37 | 13.39 | 18 | 61961 | 1312 | 29511236 |
Urinary retention | 18.28 | 13.39 | 24 | 61955 | 31874 | 29480674 |
Methaemoglobinaemia | 18.01 | 13.39 | 25 | 61954 | 2646 | 29509902 |
Andersen-Tawil syndrome | 17.92 | 13.39 | 4 | 61975 | 4 | 29512544 |
Neonatal lupus erythematosus | 17.92 | 13.39 | 4 | 61975 | 4 | 29512544 |
Therapeutic response unexpected | 17.90 | 13.39 | 49 | 61930 | 8589 | 29503959 |
Cardiogenic shock | 17.75 | 13.39 | 9 | 61970 | 19181 | 29493367 |
Granuloma skin | 17.73 | 13.39 | 13 | 61966 | 635 | 29511913 |
Blood creatine phosphokinase increased | 17.35 | 13.39 | 37 | 61942 | 40607 | 29471941 |
Hypocalcaemia | 17.24 | 13.39 | 11 | 61968 | 20654 | 29491894 |
Neutrophil Pelger-Huet anomaly present | 17.19 | 13.39 | 9 | 61970 | 239 | 29512309 |
Scleroderma renal crisis | 17.12 | 13.39 | 7 | 61972 | 103 | 29512445 |
Oral pustule | 17.08 | 13.39 | 9 | 61970 | 242 | 29512306 |
Viral load abnormal | 16.94 | 13.39 | 6 | 61973 | 58 | 29512490 |
Peritonitis | 16.94 | 13.39 | 5 | 61974 | 14819 | 29497729 |
Lupus pneumonitis | 16.85 | 13.39 | 6 | 61973 | 59 | 29512489 |
Device related infection | 16.59 | 13.39 | 6 | 61973 | 15630 | 29496918 |
Unevaluable event | 16.56 | 13.39 | 23 | 61956 | 29828 | 29482720 |
Gamma-glutamyltransferase increased | 16.50 | 13.39 | 19 | 61960 | 26718 | 29485830 |
Lymphocyte count decreased | 16.43 | 13.39 | 10 | 61969 | 19261 | 29493287 |
Bronchopulmonary aspergillosis | 16.36 | 13.39 | 60 | 61919 | 12284 | 29500264 |
Melaena | 16.33 | 13.39 | 25 | 61954 | 31151 | 29481397 |
Angioedema | 16.33 | 13.39 | 26 | 61953 | 31889 | 29480659 |
Stent placement | 16.29 | 13.39 | 31 | 61948 | 4275 | 29508273 |
Maternal exposure before pregnancy | 16.24 | 13.39 | 11 | 61968 | 473 | 29512075 |
Joint warmth | 16.19 | 13.39 | 9 | 61970 | 270 | 29512278 |
Abscess | 16.05 | 13.39 | 51 | 61928 | 9711 | 29502837 |
Cytokine storm | 16.03 | 13.39 | 12 | 61967 | 605 | 29511943 |
Red blood cell count decreased | 16.01 | 13.39 | 18 | 61961 | 25584 | 29486964 |
Ataxia | 15.96 | 13.39 | 3 | 61976 | 12100 | 29500448 |
Pancreatitis | 15.94 | 13.39 | 30 | 61949 | 34484 | 29478064 |
Angina pectoris | 15.91 | 13.39 | 21 | 61958 | 27829 | 29484719 |
Bradycardia | 15.90 | 13.39 | 77 | 61902 | 65552 | 29446996 |
Stress ulcer | 15.86 | 13.39 | 6 | 61973 | 71 | 29512477 |
Blood pressure diastolic increased | 15.79 | 13.39 | 28 | 61951 | 3658 | 29508890 |
Viral vasculitis | 15.78 | 13.39 | 6 | 61973 | 72 | 29512476 |
Q fever | 15.74 | 13.39 | 7 | 61972 | 128 | 29512420 |
Tuberculin test positive | 15.72 | 13.39 | 15 | 61964 | 1058 | 29511490 |
Bursa removal | 15.64 | 13.39 | 7 | 61972 | 130 | 29512418 |
Anomalous pulmonary venous connection | 15.56 | 13.39 | 6 | 61973 | 75 | 29512473 |
Oedema | 15.55 | 13.39 | 39 | 61940 | 40444 | 29472104 |
Gout | 15.54 | 13.39 | 8 | 61971 | 16903 | 29495645 |
Metastases to liver | 15.51 | 13.39 | 3 | 61976 | 11853 | 29500695 |
Wrist surgery | 15.50 | 13.39 | 7 | 61972 | 133 | 29512415 |
Haematocrit decreased | 15.47 | 13.39 | 23 | 61956 | 28999 | 29483549 |
Visual acuity reduced | 15.29 | 13.39 | 6 | 61973 | 14870 | 29497678 |
Colitis ulcerative | 15.16 | 13.39 | 4 | 61975 | 12765 | 29499783 |
Ankle deformity | 15.09 | 13.39 | 8 | 61971 | 218 | 29512330 |
Pulmonary oedema | 15.03 | 13.39 | 43 | 61936 | 42692 | 29469856 |
Blood parathyroid hormone decreased | 14.97 | 13.39 | 13 | 61966 | 811 | 29511737 |
Raoultella ornithinolytica infection | 14.92 | 13.39 | 4 | 61975 | 13 | 29512535 |
Hepatic failure | 14.90 | 13.39 | 27 | 61952 | 31485 | 29481063 |
Dysuria | 14.90 | 13.39 | 15 | 61964 | 22425 | 29490123 |
Disseminated intravascular coagulation | 14.88 | 13.39 | 12 | 61967 | 19968 | 29492580 |
Shoulder operation | 14.85 | 13.39 | 13 | 61966 | 820 | 29511728 |
Chronic kidney disease | 14.84 | 13.39 | 34 | 61945 | 36382 | 29476166 |
Synovial cyst | 14.70 | 13.39 | 19 | 61960 | 1878 | 29510670 |
Speech sound disorder | 14.56 | 13.39 | 7 | 61972 | 154 | 29512394 |
Acute respiratory distress syndrome | 14.53 | 13.39 | 90 | 61889 | 22845 | 29489703 |
Vasculitis | 14.51 | 13.39 | 43 | 61936 | 7885 | 29504663 |
Nervousness | 14.50 | 13.39 | 3 | 61976 | 11303 | 29501245 |
Retro-orbital neoplasm | 14.48 | 13.39 | 4 | 61975 | 15 | 29512533 |
Electrolyte imbalance | 14.44 | 13.39 | 3 | 61976 | 11271 | 29501277 |
Cyanosis | 14.43 | 13.39 | 3 | 61976 | 11264 | 29501284 |
Faeces discoloured | 14.37 | 13.39 | 5 | 61974 | 13346 | 29499202 |
Tender joint count increased | 14.34 | 13.39 | 5 | 61974 | 46 | 29512502 |
Encephalopathy | 14.32 | 13.39 | 27 | 61952 | 31016 | 29481532 |
Aortoenteric fistula | 14.22 | 13.39 | 6 | 61973 | 96 | 29512452 |
Localised infection | 14.17 | 13.39 | 62 | 61917 | 13754 | 29498794 |
Disseminated strongyloidiasis | 14.11 | 13.39 | 6 | 61973 | 98 | 29512450 |
Oedema peripheral | 14.00 | 13.39 | 144 | 61835 | 103413 | 29409135 |
Hallucination, visual | 13.95 | 13.39 | 7 | 61972 | 15008 | 29497540 |
Full blood count abnormal | 13.95 | 13.39 | 7 | 61972 | 15006 | 29497542 |
Tubulointerstitial nephritis | 13.90 | 13.39 | 10 | 61969 | 17633 | 29494915 |
Malnutrition | 13.83 | 13.39 | 3 | 61976 | 10938 | 29501610 |
Ventricular fibrillation | 13.81 | 13.39 | 8 | 61971 | 15825 | 29496723 |
Neurological examination abnormal | 13.79 | 13.39 | 8 | 61971 | 261 | 29512287 |
Aortic bruit | 13.68 | 13.39 | 7 | 61972 | 177 | 29512371 |
Therapeutic product effect delayed | 13.56 | 13.39 | 14 | 61965 | 1086 | 29511462 |
Herpes dermatitis | 13.46 | 13.39 | 5 | 61974 | 56 | 29512492 |
Product dose omission issue | 13.45 | 13.39 | 133 | 61846 | 96250 | 29416298 |
Urinary incontinence | 13.44 | 13.39 | 9 | 61970 | 16472 | 29496076 |
Olfactory nerve disorder | 13.39 | 13.39 | 4 | 61975 | 21 | 29512527 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug ineffective | 6525.90 | 11.13 | 13554 | 313546 | 826693 | 63344939 |
Drug intolerance | 5127.42 | 11.13 | 5502 | 321598 | 182490 | 63989142 |
Joint swelling | 3677.23 | 11.13 | 4971 | 322129 | 210411 | 63961221 |
Synovitis | 3512.53 | 11.13 | 3346 | 323754 | 95744 | 64075888 |
Rheumatoid arthritis | 3371.38 | 11.13 | 4155 | 322945 | 160139 | 64011493 |
Off label use | 3198.07 | 11.13 | 8666 | 318434 | 624140 | 63547492 |
Contraindicated product administered | 3127.25 | 11.13 | 3265 | 323835 | 104564 | 64067068 |
Treatment failure | 2842.72 | 11.13 | 3225 | 323875 | 113591 | 64058041 |
Therapeutic product effect decreased | 2079.89 | 11.13 | 2738 | 324362 | 112613 | 64059019 |
Arthropathy | 2035.38 | 11.13 | 2776 | 324324 | 118191 | 64053441 |
Arthralgia | 1446.08 | 11.13 | 5220 | 321880 | 437040 | 63734592 |
Systemic lupus erythematosus | 1395.97 | 11.13 | 1841 | 325259 | 75771 | 64095861 |
Pain | 1289.42 | 11.13 | 5880 | 321220 | 547631 | 63624001 |
C-reactive protein abnormal | 1270.36 | 11.13 | 1105 | 325995 | 27942 | 64143690 |
Death | 1213.35 | 11.13 | 467 | 326633 | 482238 | 63689394 |
Hand deformity | 1211.48 | 11.13 | 1542 | 325558 | 61229 | 64110403 |
Rheumatoid factor positive | 1075.99 | 11.13 | 1094 | 326006 | 33844 | 64137788 |
Red blood cell sedimentation rate abnormal | 1071.88 | 11.13 | 788 | 326312 | 15518 | 64156114 |
Musculoskeletal stiffness | 1055.62 | 11.13 | 2085 | 325015 | 121121 | 64050511 |
Swelling | 1021.21 | 11.13 | 2405 | 324695 | 157813 | 64013819 |
Abdominal discomfort | 999.40 | 11.13 | 2583 | 324517 | 179739 | 63991893 |
Pemphigus | 990.95 | 11.13 | 1374 | 325726 | 59327 | 64112305 |
Peripheral swelling | 968.68 | 11.13 | 2785 | 324315 | 206368 | 63965264 |
Anti-cyclic citrullinated peptide antibody positive | 949.04 | 11.13 | 1213 | 325887 | 48349 | 64123283 |
Acute kidney injury | 905.08 | 11.13 | 583 | 326517 | 448657 | 63722975 |
Alopecia | 829.34 | 11.13 | 2270 | 324830 | 163420 | 64008212 |
Drug hypersensitivity | 826.73 | 11.13 | 2868 | 324232 | 234947 | 63936685 |
Glossodynia | 820.77 | 11.13 | 1301 | 325799 | 63395 | 64108237 |
Therapeutic product effect incomplete | 791.10 | 11.13 | 1671 | 325429 | 101811 | 64069821 |
Hepatic enzyme increased | 763.71 | 11.13 | 1891 | 325209 | 128052 | 64043580 |
Condition aggravated | 754.45 | 11.13 | 3805 | 323295 | 368621 | 63803011 |
Red blood cell sedimentation rate increased | 733.84 | 11.13 | 848 | 326252 | 30387 | 64141245 |
Completed suicide | 718.98 | 11.13 | 134 | 326966 | 224280 | 63947352 |
Loss of personal independence in daily activities | 679.97 | 11.13 | 1275 | 325825 | 71179 | 64100453 |
Febrile neutropenia | 648.21 | 11.13 | 91 | 327009 | 187566 | 63984066 |
Pericarditis | 640.84 | 11.13 | 1143 | 325957 | 61373 | 64110259 |
Anaemia | 638.04 | 11.13 | 589 | 326511 | 378091 | 63793541 |
C-reactive protein increased | 561.40 | 11.13 | 1385 | 325715 | 93524 | 64078108 |
Gastrointestinal disorder | 560.42 | 11.13 | 1337 | 325763 | 88372 | 64083260 |
Hypersensitivity | 527.83 | 11.13 | 2183 | 324917 | 194269 | 63977363 |
Hypotension | 527.81 | 11.13 | 696 | 326404 | 380278 | 63791354 |
Wound | 511.75 | 11.13 | 1171 | 325929 | 75306 | 64096326 |
Dehydration | 504.42 | 11.13 | 234 | 326866 | 216529 | 63955103 |
Bone erosion | 492.52 | 11.13 | 434 | 326666 | 11161 | 64160471 |
Malignant neoplasm progression | 469.60 | 11.13 | 25 | 327075 | 112846 | 64058786 |
Constipation | 464.53 | 11.13 | 295 | 326805 | 229042 | 63942590 |
Arthritis | 462.08 | 11.13 | 1191 | 325909 | 82623 | 64089009 |
Infusion related reaction | 447.46 | 11.13 | 1835 | 325265 | 162632 | 64009000 |
Rash | 445.27 | 11.13 | 3899 | 323201 | 454650 | 63716982 |
Helicobacter infection | 440.95 | 11.13 | 738 | 326362 | 37624 | 64134008 |
Infection | 440.12 | 11.13 | 1981 | 325119 | 182899 | 63988733 |
Toxicity to various agents | 435.46 | 11.13 | 734 | 326366 | 362779 | 63808853 |
Discomfort | 434.27 | 11.13 | 1138 | 325962 | 79740 | 64091892 |
Drug abuse | 432.49 | 11.13 | 75 | 327025 | 132299 | 64039333 |
Retinal toxicity | 431.12 | 11.13 | 184 | 326916 | 1146 | 64170486 |
Maternal exposure during pregnancy | 419.23 | 11.13 | 1252 | 325848 | 94632 | 64077000 |
Sleep disorder due to general medical condition, insomnia type | 415.57 | 11.13 | 586 | 326514 | 25684 | 64145948 |
Duodenal ulcer perforation | 397.81 | 11.13 | 666 | 326434 | 33959 | 64137673 |
Seizure | 389.97 | 11.13 | 179 | 326921 | 166713 | 64004919 |
Hyponatraemia | 379.14 | 11.13 | 139 | 326961 | 148200 | 64023432 |
Osteoarthritis | 375.15 | 11.13 | 925 | 326175 | 62411 | 64109221 |
Psoriatic arthropathy | 365.94 | 11.13 | 729 | 326371 | 42552 | 64129080 |
Neutropenia | 362.93 | 11.13 | 408 | 326692 | 239216 | 63932416 |
Muscle injury | 362.10 | 11.13 | 551 | 326549 | 25886 | 64145746 |
Irritable bowel syndrome | 352.14 | 11.13 | 659 | 326441 | 36710 | 64134922 |
Rheumatoid nodule | 351.40 | 11.13 | 375 | 326725 | 12276 | 64159356 |
Sinusitis | 345.89 | 11.13 | 1562 | 325538 | 144366 | 64027266 |
Product use issue | 341.88 | 11.13 | 1600 | 325500 | 150115 | 64021517 |
Mobility decreased | 338.18 | 11.13 | 1081 | 326019 | 84759 | 64086873 |
Ill-defined disorder | 335.88 | 11.13 | 711 | 326389 | 43341 | 64128291 |
Lower respiratory tract infection | 333.97 | 11.13 | 1148 | 325952 | 93466 | 64078166 |
Thrombocytopenia | 331.38 | 11.13 | 388 | 326712 | 223413 | 63948219 |
Folliculitis | 330.25 | 11.13 | 567 | 326533 | 29510 | 64142122 |
Inflammation | 322.50 | 11.13 | 891 | 326209 | 64409 | 64107223 |
Hyperkalaemia | 322.30 | 11.13 | 61 | 327039 | 101068 | 64070564 |
Impaired work ability | 320.75 | 11.13 | 391 | 326709 | 14828 | 64156804 |
Overdose | 309.80 | 11.13 | 215 | 326885 | 159351 | 64012281 |
Gastrointestinal haemorrhage | 307.37 | 11.13 | 143 | 326957 | 132169 | 64039463 |
Somnolence | 306.93 | 11.13 | 348 | 326752 | 203297 | 63968335 |
Tremor | 303.67 | 11.13 | 188 | 326912 | 148042 | 64023590 |
Knee arthroplasty | 303.06 | 11.13 | 514 | 326586 | 26485 | 64145147 |
Impaired healing | 302.46 | 11.13 | 829 | 326271 | 59644 | 64111988 |
Rhabdomyolysis | 293.01 | 11.13 | 55 | 327045 | 91671 | 64079961 |
Fibromyalgia | 292.69 | 11.13 | 594 | 326506 | 35137 | 64136495 |
Dyspnoea | 290.51 | 11.13 | 2296 | 324804 | 716378 | 63455254 |
Atrial fibrillation | 285.36 | 11.13 | 268 | 326832 | 170821 | 64000811 |
Platelet count decreased | 280.55 | 11.13 | 262 | 326838 | 167449 | 64004183 |
Bradycardia | 275.78 | 11.13 | 127 | 326973 | 118092 | 64053540 |
Musculoskeletal disorder | 273.71 | 11.13 | 393 | 326707 | 17513 | 64154119 |
Disability | 271.71 | 11.13 | 322 | 326778 | 11850 | 64159782 |
Cardio-respiratory arrest | 258.55 | 11.13 | 88 | 327012 | 98305 | 64073327 |
Coma | 252.70 | 11.13 | 66 | 327034 | 87549 | 64084083 |
Decreased appetite | 245.06 | 11.13 | 678 | 326422 | 280611 | 63891021 |
Cardiac arrest | 244.60 | 11.13 | 252 | 326848 | 153812 | 64017820 |
Intentional product use issue | 239.62 | 11.13 | 1039 | 326061 | 94325 | 64077307 |
Depressed level of consciousness | 239.38 | 11.13 | 59 | 327041 | 81377 | 64090255 |
Lactic acidosis | 236.66 | 11.13 | 20 | 327080 | 61390 | 64110242 |
Nasopharyngitis | 234.46 | 11.13 | 1750 | 325350 | 194323 | 63977309 |
Drug tolerance decreased | 233.51 | 11.13 | 229 | 326871 | 6769 | 64164863 |
Neutrophil count decreased | 232.69 | 11.13 | 53 | 327047 | 77143 | 64094489 |
Hip arthroplasty | 232.42 | 11.13 | 401 | 326699 | 20950 | 64150682 |
Renal failure | 231.19 | 11.13 | 352 | 326748 | 181336 | 63990296 |
Sepsis | 230.38 | 11.13 | 517 | 326583 | 229824 | 63941808 |
Joint range of motion decreased | 230.12 | 11.13 | 378 | 326722 | 18965 | 64152667 |
Syncope | 225.05 | 11.13 | 281 | 326819 | 157354 | 64014278 |
Musculoskeletal pain | 223.15 | 11.13 | 910 | 326190 | 80384 | 64091248 |
Blood parathyroid hormone decreased | 221.83 | 11.13 | 228 | 326872 | 7138 | 64164494 |
Panniculitis | 220.21 | 11.13 | 248 | 326852 | 8631 | 64163001 |
Grip strength decreased | 216.51 | 11.13 | 282 | 326818 | 11442 | 64160190 |
Granuloma skin | 216.30 | 11.13 | 206 | 326894 | 5868 | 64165764 |
Anxiety | 214.14 | 11.13 | 441 | 326659 | 202208 | 63969424 |
Agitation | 213.86 | 11.13 | 90 | 327010 | 88277 | 64083355 |
Retinopathy | 208.51 | 11.13 | 157 | 326943 | 3208 | 64168424 |
Tachycardia | 207.97 | 11.13 | 272 | 326828 | 149307 | 64022325 |
White blood cell count decreased | 206.42 | 11.13 | 300 | 326800 | 157537 | 64014095 |
Dizziness | 206.14 | 11.13 | 1307 | 325793 | 428856 | 63742776 |
Pneumonia | 204.33 | 11.13 | 1835 | 325265 | 557741 | 63613891 |
Hallucination | 203.94 | 11.13 | 58 | 327042 | 72730 | 64098902 |
Joint stiffness | 203.73 | 11.13 | 466 | 326634 | 29938 | 64141694 |
Metabolic acidosis | 203.58 | 11.13 | 54 | 327046 | 70904 | 64100728 |
Cardiac failure | 200.67 | 11.13 | 225 | 326875 | 132148 | 64039484 |
Herpes zoster | 198.33 | 11.13 | 862 | 326238 | 78325 | 64093307 |
Pulmonary fibrosis | 198.06 | 11.13 | 456 | 326644 | 29422 | 64142210 |
Epistaxis | 196.06 | 11.13 | 128 | 326972 | 98003 | 64073629 |
International normalised ratio increased | 195.85 | 11.13 | 78 | 327022 | 79089 | 64092543 |
Abdominal pain | 193.55 | 11.13 | 870 | 326230 | 311505 | 63860127 |
Blister | 191.91 | 11.13 | 867 | 326233 | 80100 | 64091532 |
Cerebrovascular accident | 189.40 | 11.13 | 252 | 326848 | 137331 | 64034301 |
Fall | 186.83 | 11.13 | 1292 | 325808 | 415534 | 63756098 |
Disease progression | 186.53 | 11.13 | 268 | 326832 | 141412 | 64030220 |
Polyarthritis | 186.17 | 11.13 | 238 | 326862 | 9477 | 64162155 |
Cardiac failure congestive | 184.04 | 11.13 | 235 | 326865 | 130345 | 64041287 |
Therapeutic response decreased | 182.98 | 11.13 | 632 | 326468 | 51556 | 64120076 |
Nodule | 179.76 | 11.13 | 325 | 326775 | 17622 | 64154010 |
Maculopathy | 178.53 | 11.13 | 127 | 326973 | 2369 | 64169263 |
Respiratory arrest | 177.48 | 11.13 | 28 | 327072 | 52957 | 64118675 |
Lupus nephritis | 177.22 | 11.13 | 125 | 326975 | 2299 | 64169333 |
Drug interaction | 173.44 | 11.13 | 1100 | 326000 | 360983 | 63810649 |
Joint effusion | 170.78 | 11.13 | 271 | 326829 | 13202 | 64158430 |
Blood glucose increased | 168.95 | 11.13 | 149 | 326951 | 97924 | 64073708 |
Oedema peripheral | 167.79 | 11.13 | 528 | 326572 | 209789 | 63961843 |
Pyrexia | 165.08 | 11.13 | 1926 | 325174 | 556718 | 63614914 |
Fine motor skill dysfunction | 164.74 | 11.13 | 158 | 326942 | 4541 | 64167091 |
Neoplasm progression | 164.48 | 11.13 | 11 | 327089 | 40953 | 64130679 |
Hepatic function abnormal | 163.00 | 11.13 | 61 | 327039 | 64252 | 64107380 |
Hypoglycaemia | 162.93 | 11.13 | 130 | 326970 | 89762 | 64081870 |
Pneumonia aspiration | 162.80 | 11.13 | 49 | 327051 | 59222 | 64112410 |
Vomiting | 162.08 | 11.13 | 1902 | 325198 | 549215 | 63622417 |
Cognitive disorder | 159.78 | 11.13 | 41 | 327059 | 55046 | 64116586 |
Intentional overdose | 158.16 | 11.13 | 134 | 326966 | 89810 | 64081822 |
Multiple sclerosis relapse | 156.85 | 11.13 | 14 | 327086 | 41121 | 64130511 |
Foot deformity | 154.14 | 11.13 | 290 | 326810 | 16214 | 64155418 |
Osteoporosis | 154.01 | 11.13 | 517 | 326583 | 41563 | 64130069 |
Balance disorder | 153.84 | 11.13 | 120 | 326980 | 83806 | 64087826 |
Long QT syndrome | 152.82 | 11.13 | 158 | 326942 | 4981 | 64166651 |
Pancytopenia | 152.06 | 11.13 | 311 | 326789 | 142998 | 64028634 |
Disorientation | 151.81 | 11.13 | 47 | 327053 | 55781 | 64115851 |
Tenosynovitis | 151.35 | 11.13 | 239 | 326861 | 11594 | 64160038 |
Renal impairment | 148.41 | 11.13 | 287 | 326813 | 134730 | 64036902 |
Rheumatoid factor negative | 147.18 | 11.13 | 83 | 327017 | 1010 | 64170622 |
Pulmonary embolism | 146.63 | 11.13 | 328 | 326772 | 146028 | 64025604 |
Electrocardiogram QT prolonged | 146.41 | 11.13 | 792 | 326308 | 78656 | 64092976 |
Deformity | 144.55 | 11.13 | 169 | 326931 | 6128 | 64165504 |
Plasma cell myeloma | 144.22 | 11.13 | 29 | 327071 | 46046 | 64125586 |
Suicide attempt | 144.04 | 11.13 | 91 | 327009 | 70916 | 64100716 |
Melaena | 143.97 | 11.13 | 46 | 327054 | 53502 | 64118130 |
Disturbance in attention | 143.86 | 11.13 | 19 | 327081 | 41055 | 64130577 |
Cerebral haemorrhage | 142.58 | 11.13 | 41 | 327059 | 51049 | 64120583 |
Acute myocardial infarction | 141.91 | 11.13 | 89 | 327011 | 69629 | 64102003 |
Dysphagia | 141.60 | 11.13 | 201 | 326899 | 106611 | 64065021 |
Hyperglycaemia | 141.36 | 11.13 | 66 | 327034 | 60902 | 64110730 |
Blood bilirubin increased | 140.24 | 11.13 | 58 | 327042 | 57495 | 64114137 |
Multiple organ dysfunction syndrome | 139.30 | 11.13 | 186 | 326914 | 101227 | 64070405 |
Adverse event | 139.10 | 11.13 | 479 | 326621 | 39010 | 64132622 |
Asthenia | 138.92 | 11.13 | 1444 | 325656 | 426600 | 63745032 |
X-ray abnormal | 137.79 | 11.13 | 89 | 327011 | 1406 | 64170226 |
Finger deformity | 137.48 | 11.13 | 150 | 326950 | 5036 | 64166596 |
Hyperhidrosis | 136.03 | 11.13 | 267 | 326833 | 124653 | 64046979 |
Unresponsive to stimuli | 136.00 | 11.13 | 43 | 327057 | 50350 | 64121282 |
Haemoglobin decreased | 133.88 | 11.13 | 522 | 326578 | 194541 | 63977091 |
Blood creatinine increased | 133.83 | 11.13 | 307 | 326793 | 135475 | 64036157 |
Apparent death | 133.76 | 11.13 | 110 | 326990 | 2566 | 64169066 |
Ascites | 133.47 | 11.13 | 74 | 327026 | 61927 | 64109705 |
Blood pressure decreased | 132.27 | 11.13 | 145 | 326955 | 86054 | 64085578 |
Loss of consciousness | 131.00 | 11.13 | 355 | 326745 | 148010 | 64023622 |
Respiratory failure | 130.39 | 11.13 | 402 | 326698 | 160781 | 64010851 |
Confusional state | 130.31 | 11.13 | 783 | 326317 | 260361 | 63911271 |
Encephalopathy | 129.83 | 11.13 | 68 | 327032 | 58751 | 64112881 |
Diverticulitis | 129.60 | 11.13 | 461 | 326639 | 38157 | 64133475 |
Physical disability | 129.28 | 11.13 | 101 | 326999 | 2184 | 64169448 |
Sedation | 127.90 | 11.13 | 27 | 327073 | 41435 | 64130197 |
Muscle spasms | 127.87 | 11.13 | 333 | 326767 | 140690 | 64030942 |
Dysarthria | 127.74 | 11.13 | 71 | 327029 | 59335 | 64112297 |
Hypoxia | 126.93 | 11.13 | 156 | 326944 | 87993 | 64083639 |
Restlessness | 126.72 | 11.13 | 24 | 327076 | 39761 | 64131871 |
Aggression | 125.57 | 11.13 | 39 | 327061 | 46193 | 64125439 |
Sopor | 125.13 | 11.13 | 6 | 327094 | 29655 | 64141977 |
Drug effective for unapproved indication | 124.95 | 11.13 | 122 | 326978 | 3586 | 64168046 |
Glaucoma | 124.73 | 11.13 | 264 | 326836 | 16084 | 64155548 |
Blood urea increased | 124.02 | 11.13 | 35 | 327065 | 44118 | 64127514 |
Hepatic failure | 123.82 | 11.13 | 63 | 327037 | 55331 | 64116301 |
Pleural effusion | 123.23 | 11.13 | 288 | 326812 | 126271 | 64045361 |
Jaundice | 122.95 | 11.13 | 46 | 327054 | 48466 | 64123166 |
Dyskinesia | 122.85 | 11.13 | 25 | 327075 | 39363 | 64132269 |
Pulmonary oedema | 121.09 | 11.13 | 132 | 326968 | 78542 | 64093090 |
Ulcer | 120.75 | 11.13 | 321 | 326779 | 22669 | 64148963 |
Tuberculin test positive | 120.71 | 11.13 | 110 | 326990 | 2958 | 64168674 |
Myocardial infarction | 120.12 | 11.13 | 434 | 326666 | 165387 | 64006245 |
Elbow deformity | 120.11 | 11.13 | 77 | 327023 | 1200 | 64170432 |
Product dose omission issue | 119.52 | 11.13 | 544 | 326556 | 194203 | 63977429 |
Joint destruction | 119.48 | 11.13 | 118 | 326982 | 3518 | 64168114 |
Spinal stenosis | 119.33 | 11.13 | 236 | 326864 | 13695 | 64157937 |
Joint injury | 118.10 | 11.13 | 318 | 326782 | 22629 | 64149003 |
Palmar-plantar erythrodysaesthesia syndrome | 117.91 | 11.13 | 7 | 327093 | 28812 | 64142820 |
Mental status changes | 116.53 | 11.13 | 84 | 327016 | 61078 | 64110554 |
Coronary artery disease | 116.45 | 11.13 | 82 | 327018 | 60351 | 64111281 |
Breast cancer stage III | 115.96 | 11.13 | 105 | 326995 | 2800 | 64168832 |
Adverse drug reaction | 115.40 | 11.13 | 497 | 326603 | 44967 | 64126665 |
Chest pain | 114.86 | 11.13 | 713 | 326387 | 235267 | 63936365 |
Stomatitis | 114.72 | 11.13 | 949 | 326151 | 108656 | 64062976 |
Accidental overdose | 114.06 | 11.13 | 17 | 327083 | 33540 | 64138092 |
Haematuria | 113.97 | 11.13 | 84 | 327016 | 60387 | 64111245 |
Oral mucosal exfoliation | 113.90 | 11.13 | 77 | 327023 | 1318 | 64170314 |
Joint laxity | 113.33 | 11.13 | 94 | 327006 | 2220 | 64169412 |
Urinary retention | 111.41 | 11.13 | 55 | 327045 | 49146 | 64122486 |
Shoulder arthroplasty | 110.27 | 11.13 | 99 | 327001 | 2610 | 64169022 |
Abnormal behaviour | 109.85 | 11.13 | 19 | 327081 | 33603 | 64138029 |
Bone density decreased | 109.73 | 11.13 | 188 | 326912 | 9764 | 64161868 |
Diarrhoea | 109.70 | 11.13 | 2810 | 324290 | 719894 | 63451738 |
Rheumatic fever | 109.70 | 11.13 | 181 | 326919 | 9113 | 64162519 |
SLE arthritis | 109.56 | 11.13 | 54 | 327046 | 488 | 64171144 |
Renal phospholipidosis | 109.20 | 11.13 | 35 | 327065 | 79 | 64171553 |
Haemorrhage | 108.49 | 11.13 | 146 | 326954 | 79205 | 64092427 |
Urinary tract infection | 107.98 | 11.13 | 709 | 326391 | 230887 | 63940745 |
Bone marrow failure | 106.48 | 11.13 | 55 | 327045 | 47897 | 64123735 |
Blood cholesterol increased | 105.35 | 11.13 | 518 | 326582 | 49548 | 64122084 |
Swollen joint count increased | 104.90 | 11.13 | 160 | 326940 | 7529 | 64164103 |
Myalgia | 104.06 | 11.13 | 432 | 326668 | 158185 | 64013447 |
Pain in extremity | 103.83 | 11.13 | 2134 | 324966 | 300951 | 63870681 |
Human antichimeric antibody positive | 103.48 | 11.13 | 73 | 327027 | 1343 | 64170289 |
Irritability | 103.44 | 11.13 | 29 | 327071 | 36717 | 64134915 |
Seronegative arthritis | 103.36 | 11.13 | 96 | 327004 | 2647 | 64168985 |
Musculoskeletal deformity | 102.78 | 11.13 | 55 | 327045 | 599 | 64171033 |
Neuroleptic malignant syndrome | 102.48 | 11.13 | 6 | 327094 | 24990 | 64146642 |
Diabetic ketoacidosis | 101.71 | 11.13 | 15 | 327085 | 29830 | 64141802 |
Drug withdrawal syndrome | 101.54 | 11.13 | 18 | 327082 | 31273 | 64140359 |
Epilepsy | 101.07 | 11.13 | 23 | 327077 | 33508 | 64138124 |
Liver function test increased | 100.76 | 11.13 | 366 | 326734 | 30604 | 64141028 |
Rectal haemorrhage | 100.46 | 11.13 | 99 | 327001 | 61718 | 64109914 |
Skin necrosis | 99.75 | 11.13 | 223 | 326877 | 14106 | 64157526 |
Serotonin syndrome | 98.30 | 11.13 | 38 | 327062 | 39244 | 64132388 |
Lethargy | 96.80 | 11.13 | 136 | 326964 | 72458 | 64099174 |
Body height below normal | 95.66 | 11.13 | 77 | 327023 | 1741 | 64169891 |
Tubulointerstitial nephritis | 93.57 | 11.13 | 21 | 327079 | 30888 | 64140744 |
Respiratory distress | 93.17 | 11.13 | 77 | 327023 | 52254 | 64119378 |
Arthrodesis | 93.08 | 11.13 | 80 | 327020 | 1987 | 64169645 |
Bone cyst | 92.82 | 11.13 | 82 | 327018 | 2115 | 64169517 |
Surgical failure | 92.50 | 11.13 | 55 | 327045 | 744 | 64170888 |
Rheumatoid lung | 91.95 | 11.13 | 86 | 327014 | 2393 | 64169239 |
Upper gastrointestinal haemorrhage | 91.62 | 11.13 | 32 | 327068 | 35188 | 64136444 |
Wrong technique in product usage process | 91.43 | 11.13 | 117 | 326983 | 64857 | 64106775 |
Circulatory collapse | 90.63 | 11.13 | 29 | 327071 | 33703 | 64137929 |
Hypomagnesaemia | 90.52 | 11.13 | 38 | 327062 | 37338 | 64134294 |
Blood alkaline phosphatase increased | 90.45 | 11.13 | 91 | 327009 | 56188 | 64115444 |
Blood creatine phosphokinase increased | 90.38 | 11.13 | 98 | 327002 | 58460 | 64113172 |
Haematemesis | 90.25 | 11.13 | 64 | 327036 | 46935 | 64124697 |
Generalised tonic-clonic seizure | 89.57 | 11.13 | 45 | 327055 | 39812 | 64131820 |
Contusion | 89.10 | 11.13 | 927 | 326173 | 113038 | 64058594 |
Neurotoxicity | 88.41 | 11.13 | 16 | 327084 | 27388 | 64144244 |
Orthostatic hypotension | 87.98 | 11.13 | 65 | 327035 | 46673 | 64124959 |
Osteonecrosis of jaw | 87.95 | 11.13 | 46 | 327054 | 39779 | 64131853 |
Altered state of consciousness | 87.91 | 11.13 | 41 | 327059 | 37861 | 64133771 |
Neuropathy peripheral | 86.81 | 11.13 | 305 | 326795 | 117220 | 64054412 |
Fluid retention | 86.32 | 11.13 | 105 | 326995 | 59501 | 64112131 |
Eye disorder | 85.81 | 11.13 | 250 | 326850 | 18619 | 64153013 |
Gamma-glutamyltransferase increased | 85.59 | 11.13 | 72 | 327028 | 48438 | 64123194 |
Blood calcium decreased | 84.46 | 11.13 | 14 | 327086 | 25540 | 64146092 |
Lymphocyte count decreased | 84.14 | 11.13 | 51 | 327049 | 40648 | 64130984 |
Colitis microscopic | 84.06 | 11.13 | 142 | 326958 | 7290 | 64164342 |
Fatigue | 83.60 | 11.13 | 4616 | 322484 | 744114 | 63427518 |
Metastases to bone | 83.49 | 11.13 | 5 | 327095 | 20430 | 64151202 |
Loose body in joint | 82.59 | 11.13 | 60 | 327040 | 1158 | 64170474 |
Sciatica | 82.29 | 11.13 | 258 | 326842 | 20006 | 64151626 |
Skin ulcer | 82.09 | 11.13 | 440 | 326660 | 43534 | 64128098 |
Tumour lysis syndrome | 81.78 | 11.13 | 4 | 327096 | 19436 | 64152196 |
Sleep disorder | 80.55 | 11.13 | 549 | 326551 | 59160 | 64112472 |
Vision blurred | 80.52 | 11.13 | 215 | 326885 | 90101 | 64081531 |
Emotional distress | 80.52 | 11.13 | 41 | 327059 | 35997 | 64135635 |
Acute myeloid leukaemia | 80.48 | 11.13 | 20 | 327080 | 27443 | 64144189 |
Epicondylitis | 80.03 | 11.13 | 70 | 327030 | 1781 | 64169851 |
Disseminated intravascular coagulation | 79.78 | 11.13 | 32 | 327068 | 32316 | 64139316 |
Suicidal ideation | 79.76 | 11.13 | 134 | 326966 | 66408 | 64105224 |
Investigation abnormal | 79.51 | 11.13 | 61 | 327039 | 1283 | 64170349 |
Exposure during pregnancy | 79.36 | 11.13 | 669 | 326431 | 77006 | 64094626 |
Neutropenic sepsis | 78.61 | 11.13 | 12 | 327088 | 23260 | 64148372 |
Joint arthroplasty | 78.04 | 11.13 | 72 | 327028 | 1968 | 64169664 |
Wrist deformity | 77.69 | 11.13 | 68 | 327032 | 1732 | 64169900 |
Red blood cell sedimentation rate | 77.57 | 11.13 | 95 | 327005 | 3619 | 64168013 |
Haematoma | 76.39 | 11.13 | 73 | 327027 | 46177 | 64125455 |
Mucosal inflammation | 75.97 | 11.13 | 125 | 326975 | 62459 | 64109173 |
Status epilepticus | 75.91 | 11.13 | 10 | 327090 | 21653 | 64149979 |
Dislocation of vertebra | 75.33 | 11.13 | 86 | 327014 | 3038 | 64168594 |
Cholelithiasis | 74.95 | 11.13 | 72 | 327028 | 45434 | 64126198 |
Cerebral infarction | 74.80 | 11.13 | 59 | 327041 | 40985 | 64130647 |
Chronic kidney disease | 74.76 | 11.13 | 111 | 326989 | 57808 | 64113824 |
Acute respiratory failure | 73.33 | 11.13 | 87 | 327013 | 49847 | 64121785 |
Hypokalaemia | 73.27 | 11.13 | 343 | 326757 | 121560 | 64050072 |
Sensitivity to weather change | 72.93 | 11.13 | 126 | 326974 | 6588 | 64165044 |
Cytomegalovirus infection | 72.29 | 11.13 | 50 | 327050 | 37149 | 64134483 |
Subdural haematoma | 72.10 | 11.13 | 26 | 327074 | 28028 | 64143604 |
Deep vein thrombosis | 71.77 | 11.13 | 282 | 326818 | 104900 | 64066732 |
Adverse reaction | 71.69 | 11.13 | 135 | 326965 | 7552 | 64164080 |
Intentional self-injury | 71.19 | 11.13 | 29 | 327071 | 29015 | 64142617 |
Device expulsion | 71.16 | 11.13 | 11 | 327089 | 21125 | 64150507 |
Dysuria | 71.09 | 11.13 | 65 | 327035 | 41992 | 64129640 |
Metastases to liver | 71.01 | 11.13 | 17 | 327083 | 23924 | 64147708 |
Gastric disorder | 70.90 | 11.13 | 315 | 326785 | 28882 | 64142750 |
Small intestinal obstruction | 69.41 | 11.13 | 17 | 327083 | 23556 | 64148076 |
Aphasia | 69.40 | 11.13 | 63 | 327037 | 40843 | 64130789 |
Dysgeusia | 69.05 | 11.13 | 82 | 327018 | 46965 | 64124667 |
Bone pain | 68.67 | 11.13 | 84 | 327016 | 47488 | 64124144 |
COVID-19 treatment | 68.59 | 11.13 | 37 | 327063 | 410 | 64171222 |
Femur fracture | 68.15 | 11.13 | 348 | 326752 | 33787 | 64137845 |
Hospitalisation | 67.82 | 11.13 | 178 | 326922 | 75029 | 64096603 |
Mouth ulceration | 67.77 | 11.13 | 335 | 326765 | 32109 | 64139523 |
Viral upper respiratory tract infection | 67.76 | 11.13 | 137 | 326963 | 8078 | 64163554 |
Synovial cyst | 67.75 | 11.13 | 132 | 326968 | 7575 | 64164057 |
Blood lactate dehydrogenase increased | 67.61 | 11.13 | 42 | 327058 | 33036 | 64138596 |
Intentional product misuse | 67.59 | 11.13 | 168 | 326932 | 72127 | 64099505 |
Drug eruption | 67.06 | 11.13 | 361 | 326739 | 35775 | 64135857 |
Ear pain | 67.05 | 11.13 | 279 | 326821 | 24857 | 64146775 |
Blood iron abnormal | 67.01 | 11.13 | 52 | 327048 | 1113 | 64170519 |
Bone density abnormal | 66.92 | 11.13 | 76 | 327024 | 2669 | 64168963 |
Device related infection | 66.71 | 11.13 | 36 | 327064 | 30590 | 64141042 |
Product quality issue | 66.43 | 11.13 | 34 | 327066 | 29765 | 64141867 |
Hallucination, visual | 66.28 | 11.13 | 29 | 327071 | 27805 | 64143827 |
Arrhythmia | 65.90 | 11.13 | 104 | 326996 | 52840 | 64118792 |
Basal cell carcinoma | 65.54 | 11.13 | 320 | 326780 | 30518 | 64141114 |
Therapy non-responder | 64.91 | 11.13 | 563 | 326537 | 65336 | 64106296 |
Hepatitis | 64.42 | 11.13 | 424 | 326676 | 45158 | 64126474 |
Pancreatitis | 64.34 | 11.13 | 128 | 326972 | 59479 | 64112153 |
Pallor | 64.29 | 11.13 | 61 | 327039 | 38720 | 64132912 |
Colitis | 64.19 | 11.13 | 125 | 326975 | 58549 | 64113083 |
Premature delivery | 64.16 | 11.13 | 224 | 326876 | 18365 | 64153267 |
Drug ineffective for unapproved indication | 63.99 | 11.13 | 320 | 326780 | 30813 | 64140819 |
Transient ischaemic attack | 63.79 | 11.13 | 78 | 327022 | 44104 | 64127528 |
Enthesopathy | 63.76 | 11.13 | 147 | 326953 | 9491 | 64162141 |
Wheelchair user | 63.42 | 11.13 | 97 | 327003 | 4575 | 64167057 |
Chills | 62.52 | 11.13 | 423 | 326677 | 136841 | 64034791 |
Haemoptysis | 62.34 | 11.13 | 95 | 327005 | 48953 | 64122679 |
Onychomadesis | 62.23 | 11.13 | 75 | 327025 | 2809 | 64168823 |
Product use in unapproved indication | 62.17 | 11.13 | 1249 | 325851 | 175369 | 63996263 |
Neck mass | 62.15 | 11.13 | 89 | 327011 | 3955 | 64167677 |
Hypophosphataemia | 62.02 | 11.13 | 3 | 327097 | 14717 | 64156915 |
Gastrooesophageal reflux disease | 61.91 | 11.13 | 215 | 326885 | 82928 | 64088704 |
Withdrawal syndrome | 61.70 | 11.13 | 21 | 327079 | 23471 | 64148161 |
Muscle twitching | 61.49 | 11.13 | 11 | 327089 | 18987 | 64152645 |
Cyanosis | 61.41 | 11.13 | 18 | 327082 | 22137 | 64149495 |
Terminal state | 61.37 | 11.13 | 93 | 327007 | 4351 | 64167281 |
Cardiogenic shock | 61.16 | 11.13 | 45 | 327055 | 32382 | 64139250 |
Onychomycosis | 61.06 | 11.13 | 101 | 326999 | 5095 | 64166537 |
Subacute cutaneous lupus erythematosus | 60.96 | 11.13 | 76 | 327024 | 2949 | 64168683 |
Product administration error | 60.94 | 11.13 | 32 | 327068 | 27611 | 64144021 |
Vertigo | 60.92 | 11.13 | 130 | 326970 | 58881 | 64112751 |
Clostridium difficile colitis | 60.77 | 11.13 | 31 | 327069 | 27192 | 64144440 |
Depression | 60.66 | 11.13 | 615 | 326485 | 182676 | 63988956 |
Night sweats | 60.18 | 11.13 | 350 | 326750 | 35696 | 64135936 |
Cardiac disorder | 60.12 | 11.13 | 120 | 326980 | 55696 | 64115936 |
Flushing | 59.49 | 11.13 | 202 | 326898 | 78446 | 64093186 |
Incorrect dose administered | 59.34 | 11.13 | 138 | 326962 | 60627 | 64111005 |
Tenderness | 59.04 | 11.13 | 226 | 326874 | 19376 | 64152256 |
Presbyacusis | 58.92 | 11.13 | 69 | 327031 | 2506 | 64169126 |
Myoclonus | 58.51 | 11.13 | 27 | 327073 | 25091 | 64146541 |
Haemorrhage intracranial | 58.29 | 11.13 | 24 | 327076 | 23860 | 64147772 |
Paraesthesia | 58.10 | 11.13 | 421 | 326679 | 134101 | 64037531 |
Myelosuppression | 58.07 | 11.13 | 24 | 327076 | 23806 | 64147826 |
Fear of injection | 57.85 | 11.13 | 106 | 326994 | 5806 | 64165826 |
Ileus | 57.82 | 11.13 | 22 | 327078 | 22944 | 64148688 |
Hyperthyroidism | 57.82 | 11.13 | 11 | 327089 | 18168 | 64153464 |
Extrapyramidal disorder | 57.76 | 11.13 | 14 | 327086 | 19538 | 64152094 |
Coordination abnormal | 57.30 | 11.13 | 5 | 327095 | 14959 | 64156673 |
Abdominal distension | 57.15 | 11.13 | 271 | 326829 | 95723 | 64075909 |
Hypothermia | 57.15 | 11.13 | 15 | 327085 | 19841 | 64151791 |
Limb discomfort | 57.04 | 11.13 | 281 | 326819 | 26894 | 64144738 |
Ovarian neoplasm | 56.94 | 11.13 | 36 | 327064 | 547 | 64171085 |
Flatulence | 56.93 | 11.13 | 58 | 327042 | 35608 | 64136024 |
Tachypnoea | 56.76 | 11.13 | 32 | 327068 | 26539 | 64145093 |
Blood triglycerides increased | 56.74 | 11.13 | 13 | 327087 | 18853 | 64152779 |
Inappropriate antidiuretic hormone secretion | 56.70 | 11.13 | 21 | 327079 | 22268 | 64149364 |
Poisoning | 56.70 | 11.13 | 20 | 327080 | 21859 | 64149773 |
White blood cell count increased | 56.70 | 11.13 | 160 | 326940 | 65854 | 64105778 |
Angina pectoris | 56.64 | 11.13 | 88 | 327012 | 44993 | 64126639 |
Osteoporotic fracture | 56.50 | 11.13 | 80 | 327020 | 3518 | 64168114 |
Delirium | 56.32 | 11.13 | 172 | 326928 | 69022 | 64102610 |
Multiple fractures | 56.23 | 11.13 | 106 | 326994 | 5934 | 64165698 |
Intestinal sepsis | 56.19 | 11.13 | 37 | 327063 | 605 | 64171027 |
Electrolyte imbalance | 55.97 | 11.13 | 29 | 327071 | 25214 | 64146418 |
Angioedema | 55.22 | 11.13 | 147 | 326953 | 61674 | 64109958 |
Hypervolaemia | 54.84 | 11.13 | 68 | 327032 | 38217 | 64133415 |
Haematochezia | 54.73 | 11.13 | 164 | 326936 | 66209 | 64105423 |
Gastritis | 54.69 | 11.13 | 82 | 327018 | 42536 | 64129096 |
Neck pain | 54.62 | 11.13 | 514 | 326586 | 61019 | 64110613 |
Bone swelling | 54.59 | 11.13 | 47 | 327053 | 1170 | 64170462 |
Deafness transitory | 54.58 | 11.13 | 40 | 327060 | 783 | 64170849 |
Psychotic disorder | 54.33 | 11.13 | 57 | 327043 | 34521 | 64137111 |
Muscle spasticity | 54.22 | 11.13 | 197 | 326903 | 16472 | 64155160 |
Myocardial ischaemia | 54.15 | 11.13 | 25 | 327075 | 23226 | 64148406 |
Urinary incontinence | 54.14 | 11.13 | 62 | 327038 | 36089 | 64135543 |
Paranoia | 53.95 | 11.13 | 9 | 327091 | 16343 | 64155289 |
Device dislocation | 53.80 | 11.13 | 20 | 327080 | 21158 | 64150474 |
Bone disorder | 53.62 | 11.13 | 197 | 326903 | 16562 | 64155070 |
Pancreatitis acute | 53.51 | 11.13 | 84 | 327016 | 42771 | 64128861 |
Dry skin | 53.40 | 11.13 | 112 | 326988 | 51049 | 64120583 |
Full blood count decreased | 53.03 | 11.13 | 24 | 327076 | 22558 | 64149074 |
Hypophagia | 52.93 | 11.13 | 74 | 327026 | 39513 | 64132119 |
Poisoning deliberate | 52.91 | 11.13 | 4 | 327096 | 13454 | 64158178 |
Cataract | 52.61 | 11.13 | 442 | 326658 | 50820 | 64120812 |
Chest discomfort | 52.27 | 11.13 | 359 | 326741 | 115747 | 64055885 |
Dialysis | 52.22 | 11.13 | 11 | 327089 | 16909 | 64154723 |
Spinal column injury | 51.61 | 11.13 | 55 | 327045 | 1797 | 64169835 |
Neck deformity | 51.56 | 11.13 | 53 | 327047 | 1659 | 64169973 |
Ischaemic stroke | 51.34 | 11.13 | 43 | 327057 | 28992 | 64142640 |
Pleural thickening | 51.31 | 11.13 | 66 | 327034 | 2644 | 64168988 |
Haemodialysis | 50.90 | 11.13 | 12 | 327088 | 17065 | 64154567 |
Second primary malignancy | 50.46 | 11.13 | 3 | 327097 | 12334 | 64159298 |
Intestinal obstruction | 50.37 | 11.13 | 66 | 327034 | 36220 | 64135412 |
Tuberculosis | 50.20 | 11.13 | 163 | 326937 | 12875 | 64158757 |
Aspiration | 50.06 | 11.13 | 12 | 327088 | 16873 | 64154759 |
Injection site reaction | 49.84 | 11.13 | 406 | 326694 | 46258 | 64125374 |
Blood potassium decreased | 49.67 | 11.13 | 80 | 327020 | 40319 | 64131313 |
Hypoalbuminaemia | 49.65 | 11.13 | 14 | 327086 | 17660 | 64153972 |
Cholestasis | 49.60 | 11.13 | 95 | 327005 | 44777 | 64126855 |
Infusion site reaction | 49.58 | 11.13 | 57 | 327043 | 2029 | 64169603 |
Ataxia | 49.52 | 11.13 | 25 | 327075 | 22059 | 64149573 |
Neoplasm malignant | 49.50 | 11.13 | 252 | 326848 | 24436 | 64147196 |
Pleural fibrosis | 49.32 | 11.13 | 80 | 327020 | 3970 | 64167662 |
Miosis | 49.29 | 11.13 | 5 | 327095 | 13261 | 64158371 |
Thyroid neoplasm | 49.20 | 11.13 | 64 | 327036 | 2593 | 64169039 |
Erectile dysfunction | 48.95 | 11.13 | 4 | 327096 | 12623 | 64159009 |
Wheezing | 48.25 | 11.13 | 227 | 326873 | 80352 | 64091280 |
Palpitations | 48.07 | 11.13 | 321 | 326779 | 104167 | 64067465 |
Pemphigoid | 47.97 | 11.13 | 5 | 327095 | 12981 | 64158651 |
Dry eye | 47.94 | 11.13 | 281 | 326819 | 28738 | 64142894 |
Mycotic allergy | 47.75 | 11.13 | 40 | 327060 | 958 | 64170674 |
Hepatic enzyme abnormal | 47.71 | 11.13 | 97 | 327003 | 5742 | 64165890 |
Hepatocellular injury | 47.24 | 11.13 | 99 | 327001 | 45136 | 64126496 |
Swollen tongue | 47.07 | 11.13 | 65 | 327035 | 34889 | 64136743 |
Blood sodium decreased | 46.99 | 11.13 | 48 | 327052 | 29434 | 64142198 |
Mental disorder | 46.96 | 11.13 | 39 | 327061 | 26406 | 64145226 |
Graft versus host disease | 46.93 | 11.13 | 7 | 327093 | 13806 | 64157826 |
Obstructive airways disorder | 46.62 | 11.13 | 30 | 327070 | 23155 | 64148477 |
Alanine aminotransferase abnormal | 46.60 | 11.13 | 106 | 326994 | 6782 | 64164850 |
Pulmonary congestion | 46.53 | 11.13 | 32 | 327068 | 23848 | 64147784 |
Septic shock | 46.48 | 11.13 | 328 | 326772 | 105109 | 64066523 |
Glycosylated haemoglobin increased | 46.30 | 11.13 | 12 | 327088 | 16007 | 64155625 |
Chronic obstructive pulmonary disease | 46.25 | 11.13 | 194 | 326906 | 70854 | 64100778 |
Dementia | 45.83 | 11.13 | 24 | 327076 | 20742 | 64150890 |
Anti-cyclic citrullinated peptide antibody | 45.69 | 11.13 | 45 | 327055 | 1337 | 64170295 |
Hepatic encephalopathy | 45.54 | 11.13 | 25 | 327075 | 21041 | 64150591 |
Drug use disorder | 45.30 | 11.13 | 97 | 327003 | 5957 | 64165675 |
Muscle rigidity | 45.23 | 11.13 | 16 | 327084 | 17457 | 64154175 |
Anger | 45.10 | 11.13 | 12 | 327088 | 15729 | 64155903 |
Blood pressure diastolic abnormal | 45 | 11.13 | 148 | 326952 | 11769 | 64159863 |
Acute coronary syndrome | 44.60 | 11.13 | 21 | 327079 | 19289 | 64152343 |
Presyncope | 44.55 | 11.13 | 68 | 327032 | 35021 | 64136611 |
Drug specific antibody | 44.42 | 11.13 | 54 | 327046 | 2041 | 64169591 |
Coagulopathy | 44.36 | 11.13 | 58 | 327042 | 31862 | 64139770 |
Head injury | 44.30 | 11.13 | 61 | 327039 | 32781 | 64138851 |
Accidental exposure to product | 44.25 | 11.13 | 41 | 327059 | 26323 | 64145309 |
Shock haemorrhagic | 44.12 | 11.13 | 15 | 327085 | 16776 | 64154856 |
Agranulocytosis | 43.97 | 11.13 | 79 | 327021 | 38150 | 64133482 |
Malnutrition | 43.87 | 11.13 | 21 | 327079 | 19104 | 64152528 |
International normalised ratio fluctuation | 43.80 | 11.13 | 64 | 327036 | 2897 | 64168735 |
Acquired pigmented retinopathy | 43.79 | 11.13 | 11 | 327089 | 4 | 64171628 |
Blood pressure systolic abnormal | 43.56 | 11.13 | 130 | 326970 | 9812 | 64161820 |
Full blood count abnormal | 43.52 | 11.13 | 52 | 327048 | 29705 | 64141927 |
Pericardial effusion | 43.48 | 11.13 | 83 | 327017 | 39171 | 64132461 |
Speech disorder | 43.40 | 11.13 | 115 | 326985 | 48326 | 64123306 |
Mydriasis | 43.25 | 11.13 | 12 | 327088 | 15300 | 64156332 |
Limb deformity | 43.14 | 11.13 | 68 | 327032 | 3293 | 64168339 |
Joint lock | 43.06 | 11.13 | 62 | 327038 | 2769 | 64168863 |
Cellulitis | 42.94 | 11.13 | 288 | 326812 | 93369 | 64078263 |
Urine output decreased | 42.87 | 11.13 | 15 | 327085 | 16477 | 64155155 |
Dystonia | 42.84 | 11.13 | 21 | 327079 | 18844 | 64152788 |
Subarachnoid haemorrhage | 42.67 | 11.13 | 20 | 327080 | 18418 | 64153214 |
Renal tubular necrosis | 42.59 | 11.13 | 30 | 327070 | 22080 | 64149552 |
Delusion | 42.53 | 11.13 | 19 | 327081 | 17995 | 64153637 |
Lupus-like syndrome | 42.42 | 11.13 | 119 | 326981 | 8672 | 64162960 |
Nervous system disorder | 42.27 | 11.13 | 33 | 327067 | 23045 | 64148587 |
Complication associated with device | 42.26 | 11.13 | 12 | 327088 | 15068 | 64156564 |
Shock | 42.23 | 11.13 | 81 | 327019 | 38159 | 64133473 |
Lupus vasculitis | 42.20 | 11.13 | 28 | 327072 | 464 | 64171168 |
Gastrointestinal pain | 42.07 | 11.13 | 108 | 326992 | 7466 | 64164166 |
Glomerular filtration rate decreased | 41.19 | 11.13 | 24 | 327076 | 19548 | 64152084 |
Brain oedema | 41.16 | 11.13 | 31 | 327069 | 22044 | 64149588 |
Parkinsonism | 41.10 | 11.13 | 11 | 327089 | 14362 | 64157270 |
Aplastic anaemia | 41.06 | 11.13 | 10 | 327090 | 13910 | 64157722 |
Faeces discoloured | 40.89 | 11.13 | 42 | 327058 | 25687 | 64145945 |
Pneumonia viral | 40.85 | 11.13 | 109 | 326991 | 7713 | 64163919 |
Aspartate aminotransferase increased | 40.83 | 11.13 | 399 | 326701 | 119389 | 64052243 |
Dyspnoea exertional | 40.53 | 11.13 | 214 | 326886 | 73516 | 64098116 |
Hair follicle tumour benign | 40.35 | 11.13 | 26 | 327074 | 409 | 64171223 |
Thrombotic microangiopathy | 40.22 | 11.13 | 17 | 327083 | 16638 | 64154994 |
Antibody test positive | 40.00 | 11.13 | 55 | 327045 | 2352 | 64169280 |
Blood glucose decreased | 39.96 | 11.13 | 35 | 327065 | 23088 | 64148544 |
Hemiparesis | 39.63 | 11.13 | 56 | 327044 | 29771 | 64141861 |
Extremity contracture | 39.63 | 11.13 | 45 | 327055 | 1580 | 64170052 |
Myelodysplastic syndrome | 39.48 | 11.13 | 49 | 327051 | 27530 | 64144102 |
Metastases to lung | 39.48 | 11.13 | 14 | 327086 | 15250 | 64156382 |
Lipase increased | 39.37 | 11.13 | 12 | 327088 | 14390 | 64157242 |
Lower gastrointestinal haemorrhage | 39.23 | 11.13 | 11 | 327089 | 13928 | 64157704 |
Salivary hypersecretion | 39.23 | 11.13 | 7 | 327093 | 12106 | 64159526 |
Pulmonary thrombosis | 39.16 | 11.13 | 130 | 326970 | 10388 | 64161244 |
Hypersomnia | 38.98 | 11.13 | 26 | 327074 | 19691 | 64151941 |
Hyperammonaemia | 38.78 | 11.13 | 3 | 327097 | 9901 | 64161731 |
Laryngeal disorder | 38.78 | 11.13 | 34 | 327066 | 868 | 64170764 |
Pustular psoriasis | 38.43 | 11.13 | 73 | 327027 | 4110 | 64167522 |
Histoplasmosis disseminated | 38.36 | 11.13 | 49 | 327051 | 1949 | 64169683 |
Overlap syndrome | 38.36 | 11.13 | 31 | 327069 | 705 | 64170927 |
Retinitis | 38.26 | 11.13 | 50 | 327050 | 2035 | 64169597 |
Transfusion | 37.97 | 11.13 | 22 | 327078 | 17972 | 64153660 |
Neutrophil count increased | 37.89 | 11.13 | 43 | 327057 | 25131 | 64146501 |
Acute hepatic failure | 37.80 | 11.13 | 46 | 327054 | 26066 | 64145566 |
Transaminases abnormal | 37.63 | 11.13 | 31 | 327069 | 725 | 64170907 |
Petechiae | 37.59 | 11.13 | 24 | 327076 | 18602 | 64153030 |
Polyuria | 37.45 | 11.13 | 9 | 327091 | 12634 | 64158998 |
Leukocytosis | 37.42 | 11.13 | 85 | 327015 | 37655 | 64133977 |
Labelled drug-drug interaction medication error | 37.40 | 11.13 | 34 | 327066 | 22028 | 64149604 |
Metastases to central nervous system | 37.30 | 11.13 | 12 | 327088 | 13900 | 64157732 |
Arteriosclerosis coronary artery | 37.26 | 11.13 | 16 | 327084 | 15513 | 64156119 |
Exostosis | 37.05 | 11.13 | 135 | 326965 | 11303 | 64160329 |
Lyme disease | 36.89 | 11.13 | 53 | 327047 | 2362 | 64169270 |
Underdose | 36.86 | 11.13 | 46 | 327054 | 25783 | 64145849 |
Troponin increased | 36.74 | 11.13 | 16 | 327084 | 15383 | 64156249 |
Cutaneous vasculitis | 36.68 | 11.13 | 93 | 327007 | 6380 | 64165252 |
Prothrombin time prolonged | 36.54 | 11.13 | 17 | 327083 | 15724 | 64155908 |
Alanine aminotransferase increased | 36.48 | 11.13 | 491 | 326609 | 138540 | 64033092 |
Brain injury | 36.39 | 11.13 | 4 | 327096 | 9961 | 64161671 |
Wrist surgery | 36.36 | 11.13 | 30 | 327070 | 703 | 64170929 |
Bloody discharge | 36.19 | 11.13 | 41 | 327059 | 1436 | 64170196 |
Hypertensive crisis | 36.16 | 11.13 | 24 | 327076 | 18224 | 64153408 |
Psychomotor hyperactivity | 36.12 | 11.13 | 14 | 327086 | 14437 | 64157195 |
Myopathy toxic | 36.10 | 11.13 | 32 | 327068 | 829 | 64170803 |
Live birth | 36.09 | 11.13 | 132 | 326968 | 11072 | 64160560 |
Bronchospasm | 36.06 | 11.13 | 34 | 327066 | 21648 | 64149984 |
Nightmare | 36.01 | 11.13 | 32 | 327068 | 20961 | 64150671 |
Acidosis | 35.81 | 11.13 | 23 | 327077 | 17772 | 64153860 |
Restrictive cardiomyopathy | 35.79 | 11.13 | 32 | 327068 | 839 | 64170793 |
Cough | 35.78 | 11.13 | 1214 | 325886 | 300934 | 63870698 |
Osteopenia | 35.74 | 11.13 | 165 | 326935 | 15375 | 64156257 |
Infective pulmonary exacerbation of cystic fibrosis | 35.73 | 11.13 | 8 | 327092 | 11788 | 64159844 |
Pulmonary toxicity | 35.68 | 11.13 | 110 | 326990 | 8451 | 64163181 |
Mania | 35.68 | 11.13 | 19 | 327081 | 16267 | 64155365 |
Sinus bradycardia | 35.67 | 11.13 | 38 | 327062 | 22855 | 64148777 |
Infiltration anaesthesia | 35.63 | 11.13 | 17 | 327083 | 142 | 64171490 |
Antinuclear antibody positive | 35.63 | 11.13 | 90 | 327010 | 6160 | 64165472 |
Hypovolaemia | 35.53 | 11.13 | 17 | 327083 | 15469 | 64156163 |
Hypothyroidism | 35.53 | 11.13 | 97 | 327003 | 40360 | 64131272 |
Weight increased | 35.45 | 11.13 | 1370 | 325730 | 211978 | 63959654 |
Phospholipidosis | 35.45 | 11.13 | 16 | 327084 | 116 | 64171516 |
Cytology abnormal | 35.45 | 11.13 | 22 | 327078 | 323 | 64171309 |
Ankle operation | 35.36 | 11.13 | 34 | 327066 | 980 | 64170652 |
Bronchitis chronic | 35.36 | 11.13 | 68 | 327032 | 3864 | 64167768 |
Abdominal pain lower | 34.87 | 11.13 | 50 | 327050 | 26419 | 64145213 |
Drug resistance | 34.85 | 11.13 | 79 | 327021 | 35023 | 64136609 |
Haematotoxicity | 34.80 | 11.13 | 11 | 327089 | 12885 | 64158747 |
Juvenile idiopathic arthritis | 34.78 | 11.13 | 67 | 327033 | 3812 | 64167820 |
Hypocalcaemia | 34.54 | 11.13 | 103 | 326997 | 41650 | 64129982 |
Asphyxia | 34.53 | 11.13 | 4 | 327096 | 9562 | 64162070 |
Polyneuropathy | 34.51 | 11.13 | 30 | 327070 | 19864 | 64151768 |
Multiple allergies | 34.49 | 11.13 | 85 | 327015 | 5729 | 64165903 |
Coeliac disease | 34.47 | 11.13 | 99 | 327001 | 7313 | 64164319 |
Mental impairment | 34.45 | 11.13 | 20 | 327080 | 16323 | 64155309 |
Peritonitis | 34.23 | 11.13 | 46 | 327054 | 24977 | 64146655 |
Arteriosclerosis | 34.09 | 11.13 | 19 | 327081 | 15858 | 64155774 |
Lupus myocarditis | 34.09 | 11.13 | 14 | 327086 | 78 | 64171554 |
Stevens-Johnson syndrome | 34.07 | 11.13 | 77 | 327023 | 34172 | 64137460 |
Medication error | 34.05 | 11.13 | 134 | 326966 | 49832 | 64121800 |
End stage renal disease | 34.04 | 11.13 | 6 | 327094 | 10469 | 64161163 |
Hallucination, auditory | 33.94 | 11.13 | 22 | 327078 | 16917 | 64154715 |
Haemorrhagic stroke | 33.91 | 11.13 | 5 | 327095 | 9946 | 64161686 |
Blood magnesium decreased | 33.89 | 11.13 | 14 | 327086 | 13891 | 64157741 |
Gait inability | 33.26 | 11.13 | 345 | 326755 | 42023 | 64129609 |
Hypofibrinogenaemia | 33.19 | 11.13 | 43 | 327057 | 1735 | 64169897 |
Incontinence | 33.15 | 11.13 | 10 | 327090 | 12071 | 64159561 |
Metastases to lymph nodes | 33.14 | 11.13 | 3 | 327097 | 8714 | 64162918 |
Blood magnesium increased | 32.98 | 11.13 | 59 | 327041 | 3172 | 64168460 |
Anal incontinence | 32.89 | 11.13 | 18 | 327082 | 15178 | 64156454 |
Suspected suicide | 32.84 | 11.13 | 3 | 327097 | 8651 | 64162981 |
Acute pulmonary oedema | 32.70 | 11.13 | 12 | 327088 | 12797 | 64158835 |
Personality change | 32.55 | 11.13 | 3 | 327097 | 8590 | 64163042 |
Drug level decreased | 32.52 | 11.13 | 9 | 327091 | 11494 | 64160138 |
Oesophagitis | 32.49 | 11.13 | 37 | 327063 | 21593 | 64150039 |
Bacteraemia | 32.42 | 11.13 | 54 | 327046 | 26857 | 64144775 |
Drug specific antibody present | 32.33 | 11.13 | 77 | 327023 | 5077 | 64166555 |
Feeling hot | 32.05 | 11.13 | 121 | 326979 | 45542 | 64126090 |
Carpal tunnel syndrome | 32.04 | 11.13 | 162 | 326938 | 15666 | 64155966 |
Victim of child abuse | 31.89 | 11.13 | 30 | 327070 | 841 | 64170791 |
Swelling face | 31.81 | 11.13 | 173 | 326927 | 58993 | 64112639 |
Granulocytopenia | 31.79 | 11.13 | 7 | 327093 | 10433 | 64161199 |
Device issue | 31.63 | 11.13 | 41 | 327059 | 22607 | 64149025 |
Pathogen resistance | 31.60 | 11.13 | 12 | 327088 | 12531 | 64159101 |
Ejection fraction decreased | 31.53 | 11.13 | 61 | 327039 | 28646 | 64142986 |
Clostridium difficile infection | 31.53 | 11.13 | 87 | 327013 | 36076 | 64135556 |
Anhedonia | 31.51 | 11.13 | 15 | 327085 | 13691 | 64157941 |
Sinus tachycardia | 31.50 | 11.13 | 73 | 327027 | 32115 | 64139517 |
Deafness neurosensory | 31.47 | 11.13 | 87 | 327013 | 6287 | 64165345 |
Diabetes mellitus inadequate control | 31.46 | 11.13 | 37 | 327063 | 21284 | 64150348 |
Tenosynovitis stenosans | 31.40 | 11.13 | 44 | 327056 | 1916 | 64169716 |
Vascular access complication | 31.29 | 11.13 | 33 | 327067 | 1065 | 64170567 |
Respiratory disorder | 31.22 | 11.13 | 300 | 326800 | 35811 | 64135821 |
Mesenteritis | 31.16 | 11.13 | 17 | 327083 | 193 | 64171439 |
Activated partial thromboplastin time prolonged | 31.14 | 11.13 | 13 | 327087 | 12818 | 64158814 |
Toxic encephalopathy | 31.08 | 11.13 | 6 | 327094 | 9809 | 64161823 |
Butterfly rash | 31.00 | 11.13 | 34 | 327066 | 1148 | 64170484 |
Synovial fluid analysis | 30.95 | 11.13 | 39 | 327061 | 1530 | 64170102 |
Asthma | 30.86 | 11.13 | 321 | 326779 | 94904 | 64076728 |
Foot operation | 30.71 | 11.13 | 67 | 327033 | 4168 | 64167464 |
Faecaloma | 30.70 | 11.13 | 6 | 327094 | 9722 | 64161910 |
Hyperuricaemia | 30.69 | 11.13 | 7 | 327093 | 10184 | 64161448 |
Optical coherence tomography abnormal | 30.63 | 11.13 | 9 | 327091 | 13 | 64171619 |
Stress at work | 30.48 | 11.13 | 31 | 327069 | 958 | 64170674 |
Transplant rejection | 30.48 | 11.13 | 26 | 327074 | 17375 | 64154257 |
Cushingoid | 30.13 | 11.13 | 96 | 327004 | 7507 | 64164125 |
Type 2 diabetes mellitus | 30.10 | 11.13 | 284 | 326816 | 33736 | 64137896 |
Drug level increased | 30.02 | 11.13 | 82 | 327018 | 34114 | 64137518 |
Duodenal ulcer | 29.96 | 11.13 | 18 | 327082 | 14417 | 64157215 |
Feeling cold | 29.95 | 11.13 | 46 | 327054 | 23632 | 64148000 |
Metabolic encephalopathy | 29.88 | 11.13 | 3 | 327097 | 8022 | 64163610 |
Nail disorder | 29.83 | 11.13 | 104 | 326996 | 8520 | 64163112 |
Intestinal polyp | 29.81 | 11.13 | 40 | 327060 | 1671 | 64169961 |
Feeling abnormal | 29.79 | 11.13 | 487 | 326613 | 133115 | 64038517 |
Failure to thrive | 29.68 | 11.13 | 8 | 327092 | 10396 | 64161236 |
Pollakiuria | 29.67 | 11.13 | 73 | 327027 | 31457 | 64140175 |
Maternal exposure timing unspecified | 29.66 | 11.13 | 51 | 327049 | 2656 | 64168976 |
Renal injury | 29.63 | 11.13 | 21 | 327079 | 15408 | 64156224 |
Cholangitis | 29.53 | 11.13 | 9 | 327091 | 10793 | 64160839 |
Post procedural haemorrhage | 29.52 | 11.13 | 13 | 327087 | 12418 | 64159214 |
Pulmonary hypertension | 29.20 | 11.13 | 116 | 326984 | 43023 | 64128609 |
Gastric haemorrhage | 29.14 | 11.13 | 16 | 327084 | 13465 | 64158167 |
Oliguria | 29.11 | 11.13 | 19 | 327081 | 14557 | 64157075 |
Mood altered | 29.08 | 11.13 | 23 | 327077 | 15956 | 64155676 |
Cholecystitis | 29.05 | 11.13 | 34 | 327066 | 19602 | 64152030 |
Body temperature increased | 28.99 | 11.13 | 299 | 326801 | 36367 | 64135265 |
Latent tuberculosis | 28.98 | 11.13 | 51 | 327049 | 2706 | 64168926 |
Colitis ischaemic | 28.88 | 11.13 | 16 | 327084 | 13398 | 64158234 |
Cutaneous coccidioidomycosis | 28.81 | 11.13 | 9 | 327091 | 18 | 64171614 |
Eosinophil count increased | 28.73 | 11.13 | 18 | 327082 | 14094 | 64157538 |
Diffuse alopecia | 28.65 | 11.13 | 24 | 327076 | 575 | 64171057 |
Bursitis | 28.64 | 11.13 | 197 | 326903 | 21288 | 64150344 |
No adverse event | 28.63 | 11.13 | 245 | 326855 | 28316 | 64143316 |
Anovulatory cycle | 28.60 | 11.13 | 13 | 327087 | 96 | 64171536 |
Prostatic specific antigen increased | 28.51 | 11.13 | 5 | 327095 | 8755 | 64162877 |
Mycobacterium tuberculosis complex test positive | 28.50 | 11.13 | 43 | 327057 | 2004 | 64169628 |
Peripheral sensory neuropathy | 28.47 | 11.13 | 11 | 327089 | 11367 | 64160265 |
Cartilage atrophy | 28.46 | 11.13 | 15 | 327085 | 158 | 64171474 |
Fracture delayed union | 28.06 | 11.13 | 42 | 327058 | 1943 | 64169689 |
Disease susceptibility | 28.03 | 11.13 | 17 | 327083 | 239 | 64171393 |
Vasculitic rash | 27.97 | 11.13 | 42 | 327058 | 1949 | 64169683 |
Depressed mood | 27.93 | 11.13 | 110 | 326990 | 40902 | 64130730 |
Large intestine polyp | 27.92 | 11.13 | 10 | 327090 | 10827 | 64160805 |
Anuria | 27.88 | 11.13 | 33 | 327067 | 18931 | 64152701 |
Diarrhoea haemorrhagic | 27.86 | 11.13 | 11 | 327089 | 11216 | 64160416 |
Muscular weakness | 27.79 | 11.13 | 466 | 326634 | 126872 | 64044760 |
Face oedema | 27.74 | 11.13 | 52 | 327048 | 24709 | 64146923 |
Kidney transplant rejection | 27.73 | 11.13 | 7 | 327093 | 9504 | 64162128 |
Ventricular fibrillation | 27.72 | 11.13 | 49 | 327051 | 23811 | 64147821 |
Pulseless electrical activity | 27.71 | 11.13 | 15 | 327085 | 12724 | 64158908 |
Soft tissue disorder | 27.46 | 11.13 | 55 | 327045 | 3221 | 64168411 |
Hypercalcaemia | 27.17 | 11.13 | 261 | 326839 | 31155 | 64140477 |
Skin exfoliation | 27.13 | 11.13 | 126 | 326974 | 44759 | 64126873 |
Device difficult to use | 27.08 | 11.13 | 8 | 327092 | 9790 | 64161842 |
Drug tolerance | 27.07 | 11.13 | 80 | 327020 | 6005 | 64165627 |
Toxic epidermal necrolysis | 27.06 | 11.13 | 97 | 327003 | 37069 | 64134563 |
Immune thrombocytopenia | 27.02 | 11.13 | 22 | 327078 | 15044 | 64156588 |
Oedema | 26.98 | 11.13 | 317 | 326783 | 91618 | 64080014 |
Body tinea | 26.88 | 11.13 | 33 | 327067 | 1260 | 64170372 |
Multiple sclerosis | 26.75 | 11.13 | 34 | 327066 | 18907 | 64152725 |
Supraventricular tachycardia | 26.64 | 11.13 | 34 | 327066 | 18873 | 64152759 |
Sleep apnoea syndrome | 26.59 | 11.13 | 71 | 327029 | 29761 | 64141871 |
Wound infection | 26.57 | 11.13 | 147 | 326953 | 14717 | 64156915 |
Dyslipidaemia | 26.56 | 11.13 | 7 | 327093 | 9235 | 64162397 |
Sudden death | 26.43 | 11.13 | 38 | 327062 | 20058 | 64151574 |
Product prescribing error | 26.38 | 11.13 | 91 | 327009 | 35178 | 64136454 |
Smear cervix abnormal | 26.37 | 11.13 | 45 | 327055 | 2329 | 64169303 |
Coronary artery stenosis | 26.34 | 11.13 | 12 | 327088 | 11236 | 64160396 |
Hyperthermia | 26.31 | 11.13 | 24 | 327076 | 15526 | 64156106 |
Staphylococcal infection | 26.26 | 11.13 | 150 | 326950 | 50528 | 64121104 |
Red cell distribution width decreased | 26.20 | 11.13 | 30 | 327070 | 1063 | 64170569 |
Lip swelling | 26.18 | 11.13 | 79 | 327021 | 31828 | 64139804 |
C-reactive protein decreased | 26.04 | 11.13 | 42 | 327058 | 2074 | 64169558 |
Cytopenia | 26.04 | 11.13 | 24 | 327076 | 15447 | 64156185 |
Pancreatic carcinoma | 26.01 | 11.13 | 10 | 327090 | 10363 | 64161269 |
Post transplant lymphoproliferative disorder | 26.00 | 11.13 | 8 | 327092 | 9536 | 64162096 |
Cold sweat | 25.99 | 11.13 | 27 | 327073 | 16428 | 64155204 |
Infection reactivation | 25.96 | 11.13 | 41 | 327059 | 1989 | 64169643 |
Device occlusion | 25.79 | 11.13 | 9 | 327091 | 9904 | 64161728 |
Mass excision | 25.71 | 11.13 | 17 | 327083 | 280 | 64171352 |
Peritonitis bacterial | 25.71 | 11.13 | 7 | 327093 | 9036 | 64162596 |
Blood albumin decreased | 25.65 | 11.13 | 42 | 327058 | 21031 | 64150601 |
Pneumonitis | 25.60 | 11.13 | 150 | 326950 | 50215 | 64121417 |
Therapy cessation | 25.56 | 11.13 | 82 | 327018 | 32407 | 64139225 |
Ankle arthroplasty | 25.41 | 11.13 | 27 | 327073 | 879 | 64170753 |
C-reactive protein | 25.38 | 11.13 | 28 | 327072 | 952 | 64170680 |
Secretion discharge | 25.31 | 11.13 | 124 | 326976 | 11840 | 64159792 |
Haemodynamic instability | 25.25 | 11.13 | 23 | 327077 | 14889 | 64156743 |
Diplopia | 25.16 | 11.13 | 62 | 327038 | 26703 | 64144929 |
Hepatic necrosis | 25.16 | 11.13 | 6 | 327094 | 8467 | 64163165 |
Ocular toxicity | 25.10 | 11.13 | 23 | 327077 | 623 | 64171009 |
Retinal degeneration | 25.10 | 11.13 | 29 | 327071 | 1038 | 64170594 |
Right ventricular failure | 25.03 | 11.13 | 44 | 327056 | 21427 | 64150205 |
Mean platelet volume decreased | 25.01 | 11.13 | 37 | 327063 | 1694 | 64169938 |
Ageusia | 24.99 | 11.13 | 20 | 327080 | 13793 | 64157839 |
Leukoencephalopathy | 24.94 | 11.13 | 3 | 327097 | 6964 | 64164668 |
Enterocolitis | 24.92 | 11.13 | 15 | 327085 | 12003 | 64159629 |
Ileus paralytic | 24.91 | 11.13 | 6 | 327094 | 8409 | 64163223 |
Aplasia | 24.87 | 11.13 | 3 | 327097 | 6950 | 64164682 |
Angina unstable | 24.86 | 11.13 | 25 | 327075 | 15442 | 64156190 |
Weight decreased | 24.79 | 11.13 | 1190 | 325910 | 284549 | 63887083 |
Device leakage | 24.26 | 11.13 | 6 | 327094 | 8260 | 64163372 |
Memory impairment | 24.16 | 11.13 | 298 | 326802 | 85384 | 64086248 |
Retching | 24.13 | 11.13 | 25 | 327075 | 15231 | 64156401 |
Arthritis bacterial | 24.12 | 11.13 | 91 | 327009 | 7748 | 64163884 |
Chromaturia | 24.02 | 11.13 | 49 | 327051 | 22562 | 64149070 |
Gout | 23.96 | 11.13 | 45 | 327055 | 21368 | 64150264 |
Respiratory depression | 23.90 | 11.13 | 52 | 327048 | 23391 | 64148241 |
Respiratory acidosis | 23.89 | 11.13 | 10 | 327090 | 9845 | 64161787 |
Heart rate irregular | 23.86 | 11.13 | 66 | 327034 | 27347 | 64144285 |
Taste disorder | 23.81 | 11.13 | 9 | 327091 | 9424 | 64162208 |
Frequent bowel movements | 23.70 | 11.13 | 35 | 327065 | 18270 | 64153362 |
Joint dislocation | 23.67 | 11.13 | 118 | 326982 | 11347 | 64160285 |
Incoherent | 23.30 | 11.13 | 4 | 327096 | 7114 | 64164518 |
Limb operation | 23.29 | 11.13 | 47 | 327053 | 2767 | 64168865 |
Lung infiltration | 23.28 | 11.13 | 44 | 327056 | 20845 | 64150787 |
Eyelid oedema | 23.20 | 11.13 | 17 | 327083 | 12262 | 64159370 |
Precancerous cells present | 23.20 | 11.13 | 27 | 327073 | 974 | 64170658 |
Pneumonia fungal | 23.20 | 11.13 | 8 | 327092 | 8869 | 64162763 |
Proctalgia | 23.15 | 11.13 | 5 | 327095 | 7554 | 64164078 |
Needle issue | 23.14 | 11.13 | 9 | 327091 | 9263 | 64162369 |
Large intestine perforation | 23.11 | 11.13 | 18 | 327082 | 12586 | 64159046 |
Blood pressure fluctuation | 22.84 | 11.13 | 380 | 326720 | 51491 | 64120141 |
Gastritis erosive | 22.84 | 11.13 | 10 | 327090 | 9585 | 64162047 |
Infective tenosynovitis | 22.56 | 11.13 | 16 | 327084 | 297 | 64171335 |
Extradural abscess | 22.54 | 11.13 | 29 | 327071 | 1162 | 64170470 |
BK virus infection | 22.51 | 11.13 | 5 | 327095 | 7407 | 64164225 |
Cholecystitis acute | 22.43 | 11.13 | 15 | 327085 | 11345 | 64160287 |
Cardiac failure acute | 22.40 | 11.13 | 30 | 327070 | 16314 | 64155318 |
Bladder cancer | 22.34 | 11.13 | 14 | 327086 | 10960 | 64160672 |
Ketoacidosis | 22.15 | 11.13 | 4 | 327096 | 6859 | 64164773 |
Coma scale abnormal | 22.13 | 11.13 | 6 | 327094 | 7768 | 64163864 |
Partial seizures | 22.04 | 11.13 | 5 | 327095 | 7302 | 64164330 |
Ear infection | 22.03 | 11.13 | 198 | 326902 | 23206 | 64148426 |
Heart rate increased | 21.89 | 11.13 | 360 | 326740 | 98315 | 64073317 |
Adenovirus infection | 21.82 | 11.13 | 5 | 327095 | 7250 | 64164382 |
Panic attack | 21.75 | 11.13 | 46 | 327054 | 20907 | 64150725 |
Blood loss anaemia | 21.71 | 11.13 | 23 | 327077 | 13869 | 64157763 |
Amylase increased | 21.66 | 11.13 | 11 | 327089 | 9674 | 64161958 |
Scleritis | 21.59 | 11.13 | 47 | 327053 | 2919 | 64168713 |
Pneumocystis jirovecii pneumonia | 21.56 | 11.13 | 70 | 327030 | 27564 | 64144068 |
Hospice care | 21.49 | 11.13 | 6 | 327094 | 7619 | 64164013 |
Catatonia | 21.47 | 11.13 | 6 | 327094 | 7614 | 64164018 |
Eye swelling | 21.43 | 11.13 | 51 | 327049 | 22230 | 64149402 |
Abnormal dreams | 21.37 | 11.13 | 13 | 327087 | 10343 | 64161289 |
Hypoxic-ischaemic encephalopathy | 21.36 | 11.13 | 5 | 327095 | 7147 | 64164485 |
Hemiplegia | 21.26 | 11.13 | 20 | 327080 | 12748 | 64158884 |
Middle lobe syndrome | 21.22 | 11.13 | 8 | 327092 | 34 | 64171598 |
Anal abscess | 20.99 | 11.13 | 6 | 327094 | 7502 | 64164130 |
Epigastric discomfort | 20.90 | 11.13 | 79 | 327021 | 6732 | 64164900 |
Diabetic eye disease | 20.79 | 11.13 | 12 | 327088 | 153 | 64171479 |
Chorioretinitis | 20.73 | 11.13 | 21 | 327079 | 646 | 64170986 |
Device malfunction | 20.67 | 11.13 | 36 | 327064 | 17597 | 64154035 |
Androgenetic alopecia | 20.59 | 11.13 | 12 | 327088 | 156 | 64171476 |
Intestinal ischaemia | 20.54 | 11.13 | 17 | 327083 | 11532 | 64160100 |
Pathological fracture | 20.48 | 11.13 | 10 | 327090 | 8995 | 64162637 |
Anticoagulation drug level increased | 20.41 | 11.13 | 21 | 327079 | 658 | 64170974 |
Device use error | 20.40 | 11.13 | 4 | 327096 | 6467 | 64165165 |
Thirst | 20.36 | 11.13 | 25 | 327075 | 14112 | 64157520 |
Visual acuity reduced | 20.32 | 11.13 | 70 | 327030 | 27071 | 64144561 |
Interstitial lung disease | 20.30 | 11.13 | 644 | 326456 | 97088 | 64074544 |
Walking aid user | 20.23 | 11.13 | 74 | 327026 | 6207 | 64165425 |
Rash pruritic | 20.18 | 11.13 | 406 | 326694 | 56998 | 64114634 |
Pulmonary haemorrhage | 20.16 | 11.13 | 22 | 327078 | 13087 | 64158545 |
Prostate cancer | 20.10 | 11.13 | 44 | 327056 | 19751 | 64151881 |
Cutaneous lupus erythematosus | 20.10 | 11.13 | 43 | 327057 | 2639 | 64168993 |
Cerebral atrophy | 20.04 | 11.13 | 6 | 327094 | 7279 | 64164353 |
Inappropriate schedule of product administration | 20.04 | 11.13 | 338 | 326762 | 91948 | 64079684 |
Pulmonary arterial hypertension | 19.97 | 11.13 | 64 | 327036 | 25303 | 64146329 |
Natural killer-cell leukaemia | 19.95 | 11.13 | 10 | 327090 | 94 | 64171538 |
Tendon disorder | 19.89 | 11.13 | 74 | 327026 | 6258 | 64165374 |
Hepatitis C | 19.86 | 11.13 | 16 | 327084 | 10999 | 64160633 |
Spinal meningioma benign | 19.77 | 11.13 | 10 | 327090 | 96 | 64171536 |
Intervertebral disc compression | 19.74 | 11.13 | 25 | 327075 | 986 | 64170646 |
Hepatic lesion | 19.68 | 11.13 | 3 | 327097 | 5821 | 64165811 |
Nervousness | 19.67 | 11.13 | 80 | 327020 | 29476 | 64142156 |
Polydipsia | 19.66 | 11.13 | 3 | 327097 | 5818 | 64165814 |
General physical health deterioration | 19.61 | 11.13 | 842 | 326258 | 203583 | 63968049 |
Eyelid ptosis | 19.60 | 11.13 | 12 | 327088 | 9513 | 64162119 |
Kidney duplex | 19.54 | 11.13 | 6 | 327094 | 11 | 64171621 |
Gastric ulcer | 19.40 | 11.13 | 83 | 327017 | 30151 | 64141481 |
Urticarial vasculitis | 19.39 | 11.13 | 17 | 327083 | 434 | 64171198 |
Femoral neck fracture | 19.37 | 11.13 | 10 | 327090 | 8714 | 64162918 |
Skin reaction | 19.37 | 11.13 | 118 | 326982 | 12234 | 64159398 |
Refusal of treatment by patient | 19.37 | 11.13 | 9 | 327091 | 8330 | 64163302 |
Oral disorder | 19.26 | 11.13 | 93 | 327007 | 8828 | 64162804 |
Drug screen positive | 19.24 | 11.13 | 3 | 327097 | 5726 | 64165906 |
Infected seroma | 19.19 | 11.13 | 9 | 327091 | 72 | 64171560 |
Placenta accreta | 19.17 | 11.13 | 12 | 327088 | 179 | 64171453 |
Thyroid disorder | 19.17 | 11.13 | 113 | 326987 | 11579 | 64160053 |
Autoimmune haemolytic anaemia | 19.16 | 11.13 | 6 | 327094 | 7070 | 64164562 |
Trigger finger | 19.12 | 11.13 | 50 | 327050 | 3495 | 64168137 |
Fistula | 19.12 | 11.13 | 13 | 327087 | 9748 | 64161884 |
PaO2/FiO2 ratio decreased | 19.10 | 11.13 | 7 | 327093 | 27 | 64171605 |
Viral vasculitis | 19.08 | 11.13 | 11 | 327089 | 140 | 64171492 |
Double stranded DNA antibody positive | 19.07 | 11.13 | 16 | 327084 | 384 | 64171248 |
Skin toxicity | 18.98 | 11.13 | 5 | 327095 | 6597 | 64165035 |
Hepatic cancer | 18.97 | 11.13 | 7 | 327093 | 7441 | 64164191 |
Antiphospholipid syndrome | 18.93 | 11.13 | 31 | 327069 | 1551 | 64170081 |
Myocarditis | 18.91 | 11.13 | 36 | 327064 | 17007 | 64154625 |
External auditory canal atresia | 18.89 | 11.13 | 6 | 327094 | 13 | 64171619 |
Enteritis | 18.87 | 11.13 | 20 | 327080 | 12057 | 64159575 |
Neck surgery | 18.79 | 11.13 | 30 | 327070 | 1469 | 64170163 |
Rotator cuff repair | 18.79 | 11.13 | 30 | 327070 | 1469 | 64170163 |
Fear | 18.75 | 11.13 | 47 | 327053 | 20124 | 64151508 |
Amenorrhoea | 18.70 | 11.13 | 5 | 327095 | 6534 | 64165098 |
Cholecystitis chronic | 18.69 | 11.13 | 12 | 327088 | 9275 | 64162357 |
Toxic skin eruption | 18.66 | 11.13 | 44 | 327056 | 19240 | 64152392 |
Left ventricular dysfunction | 18.64 | 11.13 | 36 | 327064 | 16918 | 64154714 |
Ankylosing spondylitis | 18.62 | 11.13 | 87 | 327013 | 8147 | 64163485 |
Klebsiella infection | 18.59 | 11.13 | 24 | 327076 | 13257 | 64158375 |
Retinal coloboma | 18.58 | 11.13 | 6 | 327094 | 14 | 64171618 |
Iris coloboma | 18.58 | 11.13 | 6 | 327094 | 14 | 64171618 |
Bronchopleural fistula | 18.58 | 11.13 | 19 | 327081 | 591 | 64171041 |
Stress cardiomyopathy | 18.58 | 11.13 | 12 | 327088 | 9245 | 64162387 |
Cerebral ischaemia | 18.56 | 11.13 | 14 | 327086 | 9948 | 64161684 |
Gastric cancer | 18.51 | 11.13 | 5 | 327095 | 6488 | 64165144 |
Blood pressure systolic increased | 18.48 | 11.13 | 353 | 326747 | 49100 | 64122532 |
Rash macular | 18.48 | 11.13 | 60 | 327040 | 23625 | 64148007 |
Hepatomegaly | 18.43 | 11.13 | 36 | 327064 | 16846 | 64154786 |
Neuropsychiatric lupus | 18.42 | 11.13 | 11 | 327089 | 150 | 64171482 |
Metabolic disorder | 18.36 | 11.13 | 8 | 327092 | 7689 | 64163943 |
Drug reaction with eosinophilia and systemic symptoms | 18.29 | 11.13 | 181 | 326919 | 54036 | 64117596 |
Systemic inflammatory response syndrome | 18.29 | 11.13 | 15 | 327085 | 10220 | 64161412 |
Photosensitivity reaction | 18.27 | 11.13 | 156 | 326944 | 18017 | 64153615 |
Renal tubular disorder | 18.26 | 11.13 | 4 | 327096 | 5983 | 64165649 |
Histoplasmosis | 18.22 | 11.13 | 35 | 327065 | 1987 | 64169645 |
Gingivitis | 18.20 | 11.13 | 8 | 327092 | 7651 | 64163981 |
Electrocardiogram ST segment elevation | 18.20 | 11.13 | 7 | 327093 | 7252 | 64164380 |
Allergy to vaccine | 18.17 | 11.13 | 11 | 327089 | 154 | 64171478 |
Hyperventilation | 18.16 | 11.13 | 6 | 327094 | 6834 | 64164798 |
Shoulder operation | 18.05 | 11.13 | 36 | 327064 | 2102 | 64169530 |
Dactylitis | 18.03 | 11.13 | 34 | 327066 | 1904 | 64169728 |
Cranial nerve injury | 18.02 | 11.13 | 6 | 327094 | 16 | 64171616 |
Adenoiditis | 17.99 | 11.13 | 7 | 327093 | 33 | 64171599 |
Cytomegalovirus viraemia | 17.98 | 11.13 | 17 | 327083 | 10811 | 64160821 |
Decubitus ulcer | 17.89 | 11.13 | 25 | 327075 | 13354 | 64158278 |
Product substitution issue | 17.89 | 11.13 | 40 | 327060 | 17821 | 64153811 |
Anaphylactic shock | 17.82 | 11.13 | 86 | 327014 | 30242 | 64141390 |
Cardiomegaly | 17.79 | 11.13 | 61 | 327039 | 23623 | 64148009 |
Nausea | 17.76 | 11.13 | 3617 | 323483 | 782183 | 63389449 |
Apnoea | 17.74 | 11.13 | 16 | 327084 | 10406 | 64161226 |
Atrioventricular block first degree | 17.65 | 11.13 | 17 | 327083 | 10717 | 64160915 |
Pulmonary mass | 17.65 | 11.13 | 193 | 326907 | 23823 | 64147809 |
Hepatitis fulminant | 17.57 | 11.13 | 5 | 327095 | 6269 | 64165363 |
Peripheral coldness | 17.56 | 11.13 | 26 | 327074 | 13558 | 64158074 |
Micturition urgency | 17.52 | 11.13 | 16 | 327084 | 10343 | 64161289 |
Menopausal symptoms | 17.48 | 11.13 | 30 | 327070 | 1560 | 64170072 |
Obesity | 17.37 | 11.13 | 170 | 326930 | 20392 | 64151240 |
Sensory disturbance | 17.35 | 11.13 | 25 | 327075 | 13183 | 64158449 |
Back disorder | 17.32 | 11.13 | 98 | 327002 | 9892 | 64161740 |
Haemorrhoids | 17.23 | 11.13 | 63 | 327037 | 23938 | 64147694 |
Erythema | 17.22 | 11.13 | 774 | 326326 | 186296 | 63985336 |
Urosepsis | 17.21 | 11.13 | 56 | 327044 | 22038 | 64149594 |
Blood uric acid increased | 17.19 | 11.13 | 10 | 327090 | 8153 | 64163479 |
Hypovolaemic shock | 17.19 | 11.13 | 16 | 327084 | 10250 | 64161382 |
Transaminases increased | 17.16 | 11.13 | 144 | 326956 | 44450 | 64127182 |
Gastric ulcer haemorrhage | 17.12 | 11.13 | 10 | 327090 | 8133 | 64163499 |
Cachexia | 17.11 | 11.13 | 13 | 327087 | 9204 | 64162428 |
Exposure to toxic agent | 17.08 | 11.13 | 5 | 327095 | 6154 | 64165478 |
Diffuse idiopathic skeletal hyperostosis | 17.04 | 11.13 | 7 | 327093 | 39 | 64171593 |
Hypotonia | 17.04 | 11.13 | 19 | 327081 | 11193 | 64160439 |
Oral discomfort | 16.99 | 11.13 | 86 | 327014 | 8320 | 64163312 |
Intrauterine infection | 16.96 | 11.13 | 8 | 327092 | 65 | 64171567 |
Visual field defect | 16.93 | 11.13 | 84 | 327016 | 8062 | 64163570 |
Benign prostatic hyperplasia | 16.92 | 11.13 | 13 | 327087 | 9152 | 64162480 |
Therapy interrupted | 16.88 | 11.13 | 49 | 327051 | 19987 | 64151645 |
Haemoglobin increased | 16.86 | 11.13 | 3 | 327097 | 5198 | 64166434 |
Tongue disorder | 16.84 | 11.13 | 112 | 326988 | 11968 | 64159664 |
Central nervous system lupus | 16.80 | 11.13 | 13 | 327087 | 277 | 64171355 |
Upper limb fracture | 16.77 | 11.13 | 131 | 326969 | 14735 | 64156897 |
Joint space narrowing | 16.77 | 11.13 | 12 | 327088 | 226 | 64171406 |
Oral herpes | 16.73 | 11.13 | 179 | 326921 | 21973 | 64149659 |
Blood thyroid stimulating hormone increased | 16.66 | 11.13 | 9 | 327091 | 7645 | 64163987 |
Osteosclerosis | 16.64 | 11.13 | 47 | 327053 | 3439 | 64168193 |
Impaired quality of life | 16.61 | 11.13 | 71 | 327029 | 6400 | 64165232 |
Erysipelas | 16.61 | 11.13 | 13 | 327087 | 9068 | 64162564 |
Hypoacusis | 16.60 | 11.13 | 71 | 327029 | 25796 | 64145836 |
Incorrect product administration duration | 16.58 | 11.13 | 15 | 327085 | 9743 | 64161889 |
Bradyphrenia | 16.54 | 11.13 | 14 | 327086 | 9392 | 64162240 |
Intermenstrual bleeding | 16.51 | 11.13 | 3 | 327097 | 5122 | 64166510 |
Cardiac failure chronic | 16.47 | 11.13 | 13 | 327087 | 9028 | 64162604 |
Hypoventilation | 16.43 | 11.13 | 5 | 327095 | 6001 | 64165631 |
Mass | 16.36 | 11.13 | 133 | 326967 | 15143 | 64156489 |
Symptom masked | 16.35 | 11.13 | 25 | 327075 | 1179 | 64170453 |
Staphylococcal bacteraemia | 16.34 | 11.13 | 17 | 327083 | 10338 | 64161294 |
Hypertransaminasaemia | 16.28 | 11.13 | 76 | 327024 | 7115 | 64164517 |
Thrombosis in device | 16.27 | 11.13 | 3 | 327097 | 5068 | 64166564 |
Breast cancer metastatic | 16.25 | 11.13 | 8 | 327092 | 7161 | 64164471 |
Atelectasis | 16.20 | 11.13 | 77 | 327023 | 27189 | 64144443 |
Heart rate abnormal | 16.11 | 11.13 | 3 | 327097 | 5032 | 64166600 |
Hypernatraemia | 16.08 | 11.13 | 23 | 327077 | 12166 | 64159466 |
Cerebellar syndrome | 16.03 | 11.13 | 3 | 327097 | 5013 | 64166619 |
Bacterial sepsis | 15.90 | 11.13 | 9 | 327091 | 7448 | 64164184 |
Cyst | 15.87 | 11.13 | 110 | 326990 | 11917 | 64159715 |
Occult blood positive | 15.86 | 11.13 | 6 | 327094 | 6281 | 64165351 |
Gastrointestinal perforation | 15.80 | 11.13 | 4 | 327096 | 5420 | 64166212 |
Oxygen saturation decreased | 15.79 | 11.13 | 418 | 326682 | 106758 | 64064874 |
Adjustment disorder with depressed mood | 15.73 | 11.13 | 37 | 327063 | 2420 | 64169212 |
Rash erythematous | 15.73 | 11.13 | 164 | 326936 | 48469 | 64123163 |
External ear disorder | 15.71 | 11.13 | 8 | 327092 | 78 | 64171554 |
Retinal haemorrhage | 15.67 | 11.13 | 9 | 327091 | 7389 | 64164243 |
Blood potassium increased | 15.66 | 11.13 | 73 | 327027 | 25907 | 64145725 |
Coronary artery bypass | 15.62 | 11.13 | 5 | 327095 | 5810 | 64165822 |
Drug level below therapeutic | 15.62 | 11.13 | 9 | 327091 | 7375 | 64164257 |
Lupus enteritis | 15.60 | 11.13 | 7 | 327093 | 50 | 64171582 |
Portal hypertension | 15.58 | 11.13 | 6 | 327094 | 6213 | 64165419 |
Atrioventricular block | 15.53 | 11.13 | 23 | 327077 | 11992 | 64159640 |
Hydronephrosis | 15.53 | 11.13 | 30 | 327070 | 14095 | 64157537 |
Mean cell volume decreased | 15.51 | 11.13 | 46 | 327054 | 3460 | 64168172 |
Immobile | 15.44 | 11.13 | 66 | 327034 | 5949 | 64165683 |
Staphylococcal sepsis | 15.43 | 11.13 | 26 | 327074 | 12873 | 64158759 |
Hypercapnia | 15.41 | 11.13 | 10 | 327090 | 7684 | 64163948 |
Tendonitis | 15.37 | 11.13 | 164 | 326936 | 20118 | 64151514 |
Fundoscopy abnormal | 15.37 | 11.13 | 7 | 327093 | 52 | 64171580 |
Muscle haemorrhage | 15.36 | 11.13 | 5 | 327095 | 5748 | 64165884 |
Nystagmus | 15.34 | 11.13 | 14 | 327086 | 9054 | 64162578 |
Posterior reversible encephalopathy syndrome | 15.34 | 11.13 | 62 | 327038 | 22884 | 64148748 |
Peripheral ischaemia | 15.32 | 11.13 | 12 | 327088 | 8366 | 64163266 |
Hiccups | 15.31 | 11.13 | 12 | 327088 | 8364 | 64163268 |
Iodine allergy | 15.28 | 11.13 | 16 | 327084 | 512 | 64171120 |
Urticaria | 15.28 | 11.13 | 903 | 326197 | 146414 | 64025218 |
Infection susceptibility increased | 15.27 | 11.13 | 39 | 327061 | 2687 | 64168945 |
Injection site pain | 15.25 | 11.13 | 439 | 326661 | 110969 | 64060663 |
Larynx irritation | 15.25 | 11.13 | 9 | 327091 | 120 | 64171512 |
Carcinoid tumour pulmonary | 15.22 | 11.13 | 13 | 327087 | 320 | 64171312 |
Clinical trial participant | 15.18 | 11.13 | 9 | 327091 | 121 | 64171511 |
Oral lichen planus | 15.17 | 11.13 | 18 | 327082 | 663 | 64170969 |
Speech sound disorder | 15.14 | 11.13 | 7 | 327093 | 54 | 64171578 |
Device failure | 15.10 | 11.13 | 5 | 327095 | 5687 | 64165945 |
Blood chloride increased | 15.08 | 11.13 | 3 | 327097 | 4800 | 64166832 |
Forced expiratory volume decreased | 15.06 | 11.13 | 8 | 327092 | 6859 | 64164773 |
Thinking abnormal | 15.05 | 11.13 | 22 | 327078 | 11534 | 64160098 |
Overwork | 15.04 | 11.13 | 7 | 327093 | 55 | 64171577 |
DNA antibody | 14.98 | 11.13 | 6 | 327094 | 31 | 64171601 |
Atrioventricular block second degree | 14.94 | 11.13 | 7 | 327093 | 6447 | 64165185 |
Neutrophil/lymphocyte ratio increased | 14.93 | 11.13 | 4 | 327096 | 3 | 64171629 |
Coronary artery occlusion | 14.84 | 11.13 | 30 | 327070 | 13861 | 64157771 |
Ossicle disorder | 14.82 | 11.13 | 6 | 327094 | 32 | 64171600 |
Anaphylactoid reaction | 14.79 | 11.13 | 3 | 327097 | 4735 | 64166897 |
Escherichia sepsis | 14.78 | 11.13 | 9 | 327091 | 7156 | 64164476 |
Appendicitis | 14.76 | 11.13 | 29 | 327071 | 13540 | 64158092 |
Tricuspid valve incompetence | 14.75 | 11.13 | 41 | 327059 | 16962 | 64154670 |
Azotaemia | 14.69 | 11.13 | 10 | 327090 | 7492 | 64164140 |
Erythematotelangiectatic rosacea | 14.59 | 11.13 | 5 | 327095 | 15 | 64171617 |
Somnambulism | 14.58 | 11.13 | 4 | 327096 | 5137 | 64166495 |
Duodenitis | 14.57 | 11.13 | 8 | 327092 | 6733 | 64164899 |
Snoring | 14.54 | 11.13 | 3 | 327097 | 4679 | 64166953 |
Complement factor C4 decreased | 14.51 | 11.13 | 11 | 327089 | 227 | 64171405 |
Clostridial infection | 14.48 | 11.13 | 4 | 327096 | 5115 | 64166517 |
Vaginal haematoma | 14.45 | 11.13 | 9 | 327091 | 133 | 64171499 |
Andersen-Tawil syndrome | 14.41 | 11.13 | 4 | 327096 | 4 | 64171628 |
Bacterial test positive | 14.37 | 11.13 | 8 | 327092 | 6682 | 64164950 |
Paraesthesia oral | 14.34 | 11.13 | 28 | 327072 | 13103 | 64158529 |
Acute generalised exanthematous pustulosis | 14.30 | 11.13 | 121 | 326979 | 13937 | 64157695 |
Wrong product administered | 14.19 | 11.13 | 11 | 327089 | 7709 | 64163923 |
Hepatocellular carcinoma | 14.18 | 11.13 | 13 | 327087 | 8390 | 64163242 |
Faeces soft | 14.10 | 11.13 | 6 | 327094 | 5849 | 64165783 |
Eosinophilic pneumonia | 14.07 | 11.13 | 3 | 327097 | 4574 | 64167058 |
Gangrene | 14.07 | 11.13 | 10 | 327090 | 7328 | 64164304 |
Complement factor C3 decreased | 14.06 | 11.13 | 12 | 327088 | 295 | 64171337 |
Colon cancer | 14.05 | 11.13 | 27 | 327073 | 12712 | 64158920 |
Apathy | 14.03 | 11.13 | 22 | 327078 | 11210 | 64160422 |
Disability assessment scale score increased | 13.97 | 11.13 | 36 | 327064 | 2494 | 64169138 |
Haematocrit decreased | 13.97 | 11.13 | 194 | 326906 | 54461 | 64117171 |
Ganglioneuroma | 13.94 | 11.13 | 9 | 327091 | 142 | 64171490 |
Hiatus hernia | 13.93 | 11.13 | 53 | 327047 | 19904 | 64151728 |
Brain natriuretic peptide increased | 13.87 | 11.13 | 11 | 327089 | 7622 | 64164010 |
Eye pruritus | 13.82 | 11.13 | 27 | 327073 | 12632 | 64159000 |
Procedural complication | 13.80 | 11.13 | 10 | 327090 | 7255 | 64164377 |
Pulse absent | 13.77 | 11.13 | 15 | 327085 | 8931 | 64162701 |
Blood phosphorus increased | 13.74 | 11.13 | 4 | 327096 | 4942 | 64166690 |
Hyperbilirubinaemia | 13.73 | 11.13 | 58 | 327042 | 21147 | 64150485 |
Antinuclear antibody | 13.68 | 11.13 | 14 | 327086 | 436 | 64171196 |
Paradoxical drug reaction | 13.61 | 11.13 | 7 | 327093 | 6113 | 64165519 |
Transient hypogammaglobulinaemia of infancy | 13.59 | 11.13 | 6 | 327094 | 41 | 64171591 |
Hypoaesthesia | 13.54 | 11.13 | 572 | 326528 | 138536 | 64033096 |
Generalised oedema | 13.53 | 11.13 | 57 | 327043 | 20796 | 64150836 |
Human anti-human antibody test | 13.51 | 11.13 | 13 | 327087 | 375 | 64171257 |
Therapy change | 13.38 | 11.13 | 8 | 327092 | 6426 | 64165206 |
Brain death | 13.38 | 11.13 | 4 | 327096 | 4857 | 64166775 |
Cardiac tamponade | 13.35 | 11.13 | 13 | 327087 | 8151 | 64163481 |
Papulopustular rosacea | 13.31 | 11.13 | 5 | 327095 | 21 | 64171611 |
Blood pH decreased | 13.30 | 11.13 | 3 | 327097 | 4399 | 64167233 |
Aortic arteriosclerosis | 13.30 | 11.13 | 11 | 327089 | 7465 | 64164167 |
Skin papilloma | 13.29 | 11.13 | 57 | 327043 | 5146 | 64166486 |
Elbow operation | 13.29 | 11.13 | 11 | 327089 | 259 | 64171373 |
Hypomania | 13.29 | 11.13 | 6 | 327094 | 5648 | 64165984 |
Fibrin D dimer increased | 13.27 | 11.13 | 9 | 327091 | 6756 | 64164876 |
Dizziness postural | 13.27 | 11.13 | 18 | 327082 | 9734 | 64161898 |
Nephropathy toxic | 13.23 | 11.13 | 45 | 327055 | 17469 | 64154163 |
Dermatitis acneiform | 13.17 | 11.13 | 14 | 327086 | 8429 | 64163203 |
Central nervous system lesion | 13.17 | 11.13 | 25 | 327075 | 11824 | 64159808 |
Gingival pain | 13.13 | 11.13 | 8 | 327092 | 6359 | 64165273 |
Pleuritic pain | 13.11 | 11.13 | 78 | 327022 | 8018 | 64163614 |
Anticipatory anxiety | 13.11 | 11.13 | 11 | 327089 | 264 | 64171368 |
Accident | 13.11 | 11.13 | 69 | 327031 | 6777 | 64164855 |
Expired product administered | 13.09 | 11.13 | 7 | 327093 | 5980 | 64165652 |
Blood chloride decreased | 13.09 | 11.13 | 11 | 327089 | 7405 | 64164227 |
Gonorrhoea | 12.97 | 11.13 | 9 | 327091 | 161 | 64171471 |
Feeding disorder | 12.94 | 11.13 | 111 | 326989 | 12838 | 64158794 |
Respiration abnormal | 12.93 | 11.13 | 8 | 327092 | 6307 | 64165325 |
Parainfluenzae virus infection | 12.88 | 11.13 | 4 | 327096 | 4739 | 64166893 |
Lupus pancreatitis | 12.87 | 11.13 | 3 | 327097 | 0 | 64171632 |
Electrocardiogram abnormal | 12.85 | 11.13 | 31 | 327069 | 13450 | 64158182 |
Cytomegalovirus test positive | 12.83 | 11.13 | 5 | 327095 | 5139 | 64166493 |
Granulomatous dermatitis | 12.83 | 11.13 | 12 | 327088 | 334 | 64171298 |
Amnesia | 12.82 | 11.13 | 170 | 326930 | 48099 | 64123533 |
Lacunar infarction | 12.80 | 11.13 | 6 | 327094 | 5526 | 64166106 |
Internal haemorrhage | 12.78 | 11.13 | 12 | 327088 | 7655 | 64163977 |
Meningitis streptococcal | 12.69 | 11.13 | 9 | 327091 | 167 | 64171465 |
Injection site hypersensitivity | 12.67 | 11.13 | 27 | 327073 | 1652 | 64169980 |
Tender joint count increased | 12.63 | 11.13 | 8 | 327092 | 122 | 64171510 |
Sensory loss | 12.63 | 11.13 | 20 | 327080 | 10149 | 64161483 |
Euphoric mood | 12.62 | 11.13 | 9 | 327091 | 6582 | 64165050 |
Carotid artery stenosis | 12.57 | 11.13 | 13 | 327087 | 7928 | 64163704 |
Rheumatoid factor | 12.57 | 11.13 | 8 | 327092 | 123 | 64171509 |
Localised infection | 12.57 | 11.13 | 219 | 326881 | 29942 | 64141690 |
Compartment syndrome | 12.56 | 11.13 | 3 | 327097 | 4229 | 64167403 |
Knee deformity | 12.53 | 11.13 | 19 | 327081 | 889 | 64170743 |
Bradykinesia | 12.50 | 11.13 | 9 | 327091 | 6551 | 64165081 |
Lymphocyte percentage decreased | 12.48 | 11.13 | 4 | 327096 | 4645 | 64166987 |
Vaginal haemorrhage | 12.47 | 11.13 | 53 | 327047 | 19291 | 64152341 |
Influenza like illness | 12.43 | 11.13 | 229 | 326871 | 61473 | 64110159 |
Brain herniation | 12.40 | 11.13 | 9 | 327091 | 6524 | 64165108 |
Hypergammaglobulinaemia | 12.40 | 11.13 | 16 | 327084 | 643 | 64170989 |
Squamous cell carcinoma of skin | 12.39 | 11.13 | 26 | 327074 | 11850 | 64159782 |
Connective tissue disorder | 12.39 | 11.13 | 21 | 327079 | 1081 | 64170551 |
Initial insomnia | 12.38 | 11.13 | 7 | 327093 | 5797 | 64165835 |
Retinal injury | 12.38 | 11.13 | 11 | 327089 | 286 | 64171346 |
Acute cutaneous lupus erythematosus | 12.37 | 11.13 | 12 | 327088 | 350 | 64171282 |
Blood culture positive | 12.32 | 11.13 | 13 | 327087 | 7855 | 64163777 |
Adrenal insufficiency | 12.32 | 11.13 | 171 | 326929 | 22316 | 64149316 |
Blood disorder | 12.31 | 11.13 | 10 | 327090 | 6847 | 64164785 |
Fracture pain | 12.31 | 11.13 | 12 | 327088 | 352 | 64171280 |
Spinal X-ray abnormal | 12.30 | 11.13 | 5 | 327095 | 27 | 64171605 |
Infected varicose vein | 12.30 | 11.13 | 5 | 327095 | 27 | 64171605 |
Localised oedema | 12.29 | 11.13 | 11 | 327089 | 7180 | 64164452 |
Cerebral haematoma | 12.26 | 11.13 | 11 | 327089 | 7174 | 64164458 |
Dermatitis exfoliative | 12.26 | 11.13 | 21 | 327079 | 10331 | 64161301 |
Congestive cardiomyopathy | 12.24 | 11.13 | 21 | 327079 | 10323 | 64161309 |
Sinus node dysfunction | 12.21 | 11.13 | 10 | 327090 | 6818 | 64164814 |
Gastrointestinal necrosis | 12.21 | 11.13 | 5 | 327095 | 4987 | 64166645 |
Vasculitis | 12.20 | 11.13 | 143 | 326957 | 17952 | 64153680 |
Urine analysis abnormal | 12.20 | 11.13 | 7 | 327093 | 5749 | 64165883 |
Aspergillosis oral | 12.19 | 11.13 | 6 | 327094 | 54 | 64171578 |
International normalised ratio abnormal | 12.19 | 11.13 | 5 | 327095 | 4983 | 64166649 |
Performance status decreased | 12.13 | 11.13 | 6 | 327094 | 5358 | 64166274 |
Escherichia infection | 12.13 | 11.13 | 38 | 327062 | 15130 | 64156502 |
Foetal growth restriction | 12.13 | 11.13 | 27 | 327073 | 1703 | 64169929 |
Blindness | 12.05 | 11.13 | 64 | 327036 | 21955 | 64149677 |
Pregnancy | 11.98 | 11.13 | 160 | 326940 | 20705 | 64150927 |
Injection site mass | 11.96 | 11.13 | 46 | 327054 | 17224 | 64154408 |
Renal disorder | 11.96 | 11.13 | 118 | 326982 | 35247 | 64136385 |
Liver transplant | 11.95 | 11.13 | 3 | 327097 | 4089 | 64167543 |
Coronary arterial stent insertion | 11.95 | 11.13 | 7 | 327093 | 5685 | 64165947 |
Hallucinations, mixed | 11.94 | 11.13 | 8 | 327092 | 6044 | 64165588 |
Biopsy heart abnormal | 11.93 | 11.13 | 4 | 327096 | 11 | 64171621 |
Arthritis salmonella | 11.93 | 11.13 | 4 | 327096 | 11 | 64171621 |
Breast cancer | 11.91 | 11.13 | 211 | 326889 | 28937 | 64142695 |
Venous thrombosis | 11.84 | 11.13 | 9 | 327091 | 6372 | 64165260 |
Depressive symptom | 11.84 | 11.13 | 4 | 327096 | 4492 | 64167140 |
Viral load abnormal | 11.83 | 11.13 | 6 | 327094 | 58 | 64171574 |
Facial paresis | 11.80 | 11.13 | 5 | 327095 | 4887 | 64166745 |
Exercise tolerance decreased | 11.79 | 11.13 | 13 | 327087 | 7697 | 64163935 |
Skin discolouration | 11.76 | 11.13 | 118 | 326982 | 35137 | 64136495 |
Spinal fusion surgery | 11.75 | 11.13 | 43 | 327057 | 3608 | 64168024 |
Brain neoplasm | 11.74 | 11.13 | 5 | 327095 | 4873 | 64166759 |
Acute vestibular syndrome | 11.73 | 11.13 | 5 | 327095 | 31 | 64171601 |
Rhinitis | 11.71 | 11.13 | 23 | 327077 | 10742 | 64160890 |
Multiple system atrophy | 11.69 | 11.13 | 12 | 327088 | 375 | 64171257 |
Herpes simplex viraemia | 11.68 | 11.13 | 10 | 327090 | 247 | 64171385 |
Oral surgery | 11.67 | 11.13 | 19 | 327081 | 946 | 64170686 |
Aplasia pure red cell | 11.66 | 11.13 | 11 | 327089 | 7003 | 64164629 |
Retinal depigmentation | 11.62 | 11.13 | 11 | 327089 | 311 | 64171321 |
Hyperlactacidaemia | 11.61 | 11.13 | 5 | 327095 | 4839 | 64166793 |
Treatment noncompliance | 11.60 | 11.13 | 153 | 326947 | 43329 | 64128303 |
Hip fracture | 11.60 | 11.13 | 85 | 327015 | 27014 | 64144618 |
Intervertebral disc space narrowing | 11.55 | 11.13 | 23 | 327077 | 1341 | 64170291 |
Hepatitis cholestatic | 11.55 | 11.13 | 28 | 327072 | 12127 | 64159505 |
Blood bicarbonate decreased | 11.55 | 11.13 | 5 | 327095 | 4824 | 64166808 |
Venoocclusive disease | 11.49 | 11.13 | 3 | 327097 | 3982 | 64167650 |
Contraindication to medical treatment | 11.48 | 11.13 | 19 | 327081 | 959 | 64170673 |
Back injury | 11.47 | 11.13 | 73 | 327027 | 7684 | 64163948 |
Hyperphosphataemia | 11.47 | 11.13 | 3 | 327097 | 3978 | 64167654 |
Loss of employment | 11.44 | 11.13 | 28 | 327072 | 1879 | 64169753 |
Palindromic rheumatism | 11.39 | 11.13 | 11 | 327089 | 319 | 64171313 |
Blood calcium increased | 11.39 | 11.13 | 16 | 327084 | 8526 | 64163106 |
Pseudomonal sepsis | 11.38 | 11.13 | 6 | 327094 | 5166 | 64166466 |
Hepatic cytolysis | 11.37 | 11.13 | 35 | 327065 | 14014 | 64157618 |
Wound dehiscence | 11.27 | 11.13 | 8 | 327092 | 5866 | 64165766 |
Disseminated strongyloidiasis | 11.27 | 11.13 | 7 | 327093 | 103 | 64171529 |
Culture tissue specimen positive | 11.21 | 11.13 | 4 | 327096 | 14 | 64171618 |
Oesophageal carcinoma | 11.20 | 11.13 | 5 | 327095 | 4738 | 64166894 |
Cryptococcal meningoencephalitis | 11.20 | 11.13 | 9 | 327091 | 203 | 64171429 |
Cardiovascular disorder | 11.20 | 11.13 | 42 | 327058 | 15839 | 64155793 |
Pneumonia cytomegaloviral | 11.19 | 11.13 | 4 | 327096 | 4335 | 64167297 |
Mean cell haemoglobin decreased | 11.19 | 11.13 | 46 | 327054 | 4076 | 64167556 |
None
Source | Code | Description |
---|---|---|
ATC | P01BA02 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ANTIPROTOZOALS ANTIMALARIALS Aminoquinolines |
FDA EPC | N0000175482 | Antimalarial |
MeSH PA | D000890 | Anti-Infective Agents |
MeSH PA | D000962 | Antimalarials |
MeSH PA | D000977 | Antiparasitic Agents |
MeSH PA | D000981 | Antiprotozoal Agents |
MeSH PA | D018501 | Antirheumatic Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
CHEBI has role | CHEBI:35842 | anti-rheumatic drugs |
CHEBI has role | CHEBI:38068 | antimalarials |
CHEBI has role | CHEBI:50177 | dermatologic agent |
CHEBI has role | CHEBI:149553 | anticoronaviral drug |
FDA EPC | N0000175713 | Antirheumatic Agent |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Ovale malaria | indication | 19341001 | DOID:12919 |
Vivax malaria | indication | 27052006 | DOID:12978 |
Quartan malaria | indication | 27618009 | DOID:14324 |
Systemic lupus erythematosus | indication | 55464009 | DOID:9074 |
Falciparum malaria | indication | 62676009 | DOID:14067 |
Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
Discoid lupus erythematosus | indication | 200938002 | |
Plasmodium Malariae Malaria Prevention | indication | ||
Plasmodium Ovale Malaria Prevention | indication | ||
Malaria Prevention | indication | ||
Plasmodium Falciparum Malaria Prevention | indication | ||
Vasculitis of the skin | off-label use | 53312001 | |
Porphyria cutanea tarda | off-label use | 61860000 | DOID:3132 |
Q fever endocarditis | off-label use | 95890006 | |
Coronavirus infection | off-label use | 186747009 | |
Polymorphic light eruption | off-label use | 238525001 | |
Juvenile rheumatoid arthritis | off-label use | 410795001 | |
Hypercalcemia associated with Sarcoidosis | off-label use | ||
Alcoholism | contraindication | 7200002 | |
Psoriasis | contraindication | 9014002 | DOID:8893 |
Visual field defect | contraindication | 12184005 | |
Retinal disorder | contraindication | 29555009 | DOID:5679 |
Anemia due to enzyme deficiency | contraindication | 111577008 | |
Deficiency of glucose-6-phosphate dehydrogenase | contraindication | 124134002 | DOID:2862 |
Disease of liver | contraindication | 235856003 | DOID:409 |
Anemia | contraindication | 271737000 | DOID:2355 |
Neutropenic disorder | contraindication | 303011007 | DOID:1227 |
Disorder of macula of retina | contraindication | 312999006 | |
Disorder of eye | contraindication | 371405004 | DOID:5614 |
Visual impairment | contraindication | 397540003 | |
Porphyria | contraindication | 418470004 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 9.51 | Basic |
pKa2 | 7.83 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 7 | Membrane receptor | ANTAGONIST | IC50 | 5.56 | IUPHAR | CHEMBL | |||
Toll-like receptor 9 | Membrane receptor | ANTAGONIST | IC50 | 7.10 | IUPHAR | CHEMBL | |||
Potassium voltage-gated channel subfamily H member 2 | Ion channel | WOMBAT-PK | |||||||
Alpha-2B adrenergic receptor | GPCR | Ki | 4.14 | CHEMBL | |||||
Muscarinic acetylcholine receptor M1 | GPCR | Ki | 4.81 | CHEMBL | |||||
Muscarinic acetylcholine receptor M2 | GPCR | Ki | 5.98 | DRUG MATRIX | |||||
Muscarinic acetylcholine receptor M3 | GPCR | Ki | 5.32 | CHEMBL | |||||
Muscarinic acetylcholine receptor M4 | GPCR | Ki | 5.26 | CHEMBL | |||||
Muscarinic acetylcholine receptor M5 | GPCR | Ki | 4.70 | CHEMBL | |||||
Alpha-2C adrenergic receptor | GPCR | Ki | 4.80 | CHEMBL | |||||
Hemoglobin subunit alpha | Secreted | WOMBAT-PK | |||||||
Alpha-1D adrenergic receptor | GPCR | Ki | 5.63 | DRUG MATRIX | |||||
Transmembrane protein 97 | Enzyme | Ki | 6 | CHEMBL | |||||
Alpha-2A adrenergic receptor | GPCR | Ki | 5.19 | CHEMBL | |||||
Sigma non-opioid intracellular receptor 1 | Membrane receptor | Ki | 6.90 | CHEMBL | |||||
Genome polyprotein | Unclassified | Ki | 4.04 | CHEMBL |
ID | Source |
---|---|
4019780 | VUID |
N0000147871 | NUI |
D02114 | KEGG_DRUG |
747-36-4 | SECONDARY_CAS_RN |
4018253 | VANDF |
4019780 | VANDF |
C0020336 | UMLSCUI |
CHEBI:5801 | CHEBI |
CHEMBL1535 | ChEMBL_ID |
DB01611 | DRUGBANK_ID |
CHEMBL1690 | ChEMBL_ID |
D006886 | MESH_DESCRIPTOR_UI |
3652 | PUBCHEM_CID |
7198 | IUPHAR_LIGAND_ID |
796 | INN_ID |
4QWG6N8QKH | UNII |
153972 | RXNORM |
15082 | MMSL |
1645 | MMSL |
4852 | MMSL |
d00817 | MMSL |
002949 | NDDF |
004906 | NDDF |
13502005 | SNOMEDCT_US |
373540008 | SNOMEDCT_US |
83490000 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-2401 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 25 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-0373 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 27 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-0373 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 27 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0591-3041 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 25 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8374 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 10 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8401 | TABLET | 200 mg | ORAL | ANDA | 30 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8401 | TABLET | 200 mg | ORAL | ANDA | 30 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-5994 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 25 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-5994 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 25 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6884 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 14 sections |
HYDROXYCHLOROQUINE SULFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7046 | TABLET | 200 mg | ORAL | ANDA | 17 sections |
HYDROXYCHLOROQUINE SULFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7046 | TABLET | 200 mg | ORAL | ANDA | 17 sections |
Hydroxychloroquine Sulfate | Human Prescription Drug Label | 1 | 16571-687 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 11 sections |
Hydroxychloroquine sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16714-110 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 25 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16714-753 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 25 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16714-753 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 25 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-485 | TABLET | 200 mg | ORAL | ANDA | 26 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-561 | TABLET | 100 mg | ORAL | ANDA | 26 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-562 | TABLET | 300 mg | ORAL | ANDA | 26 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-563 | TABLET | 400 mg | ORAL | ANDA | 26 sections |
Hydroxychloroquine Sulfate | Human Prescription Drug Label | 1 | 42385-927 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 11 sections |
Hydroxychloroquine Sulfate | Human Prescription Drug Label | 1 | 43353-051 | TABLET | 200 mg | ORAL | NDA AUTHORIZED GENERIC | 24 sections |
HYDROXYCHLOROQUINE SULFATE | Human Prescription Drug Label | 1 | 43598-721 | TABLET | 200 mg | ORAL | ANDA | 17 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-2508 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 16 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-2508 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 16 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-3432 | TABLET | 200 mg | ORAL | NDA AUTHORIZED GENERIC | 24 sections |
Hydroxychloroquine Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4659 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 20 sections |
HYDROXYCHLOROQUINE SULFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-5388 | TABLET | 200 mg | ORAL | ANDA | 9 sections |
Hydroxychloroquine sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-5573 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 12 sections |
Hydroxychloroquine Sulfate | Human Prescription Drug Label | 1 | 50090-5675 | TABLET, FILM COATED | 200 mg | ORAL | ANDA | 11 sections |