cinepazide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
651 23887-46-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cinepazide maleate
  • vasodistal
  • 67350-MD
  • cinepazide
  • Molecular weight: 417.51
  • Formula: C22H31N3O5
  • CLOGP: 1.50
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 0
  • TPSA: 71.55
  • ALOGS: -2.92
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,JAK2,MAP3K21,MAP3K7,MAPK7,MAPKAPK2,MTOR,NTRK2,PDK2,PDK4,PIK3CB,PRKDC,SIK2,SIK3,STK33,TEK 31
kinase-selectivity-class ACVR2B,AXL,BRAF,CAMK2D,DDR1,EPHB4,ERBB2,IRAK3,JAK1,MAP3K21,SIK2,SIK3,ULK1 13
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C04AX27 CARDIOVASCULAR SYSTEM
PERIPHERAL VASODILATORS
PERIPHERAL VASODILATORS
Other peripheral vasodilators
MeSH PA D002317 Cardiovascular Agents
MeSH PA D014665 Vasodilator Agents
CHEBI has role CHEBI:35554 cardiovascular drug

Related Drugs by ATC class:

C04AX Other peripheral vasodilators 16 drugs
azapetinebencyclanebuflomedilbutalaminecetiedilclazosentancyclandelatefasudilifenprodilmoxisylytenaftidrofurylphenoxybenzamine show all 16 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.83 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
26328-04-1 SECONDARY_CAS_RN
C0055740 UMLSCUI
CHEBI:135676 CHEBI
CHEMBL1874750 ChEMBL_ID
DB12123 DRUGBANK_ID
C026896 MESH_SUPPLEMENTAL_RECORD_UI
5282459 PUBCHEM_CID
3206 INN_ID
67Y4P5C84X UNII
010900 NDDF
010901 NDDF

Pharmaceutical products:

None