azapetine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 265 | 146-36-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.15 | g | O |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | C04AX30 | CARDIOVASCULAR SYSTEM PERIPHERAL VASODILATORS PERIPHERAL VASODILATORS Other peripheral vasodilators |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Peripheral vascular disease | indication | 400047006 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.45 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Adrenergic receptor alpha-2 | GPCR | IC50 | 5.89 | CHEMBL | |||||
| Adrenergic receptor alpha-1 | GPCR | IC50 | 6.69 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D07178 | KEGG_DRUG |
| C0052752 | UMLSCUI |
| CHEBI:134955 | CHEBI |
| CHEMBL2110596 | ChEMBL_ID |
| DB13727 | DRUGBANK_ID |
| 8966 | PUBCHEM_CID |
| C004448 | MESH_SUPPLEMENTAL_RECORD_UI |
| 130-83-6 | SECONDARY_CAS_RN |
| 9TTR0UA2KC | UNII |
| 30827002 | SNOMEDCT_US |
| CHEMBL2103986 | ChEMBL_ID |
| 000701 | NDDF |
Pharmaceutical products:
None