camylofin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
spasmolytics with a papaverine-like action 472 54-30-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • camylofin
  • camylofine
  • camylofine chlorhydrate
  • acamylophenine
  • acamylophenine hydrochloride
  • camylofin hydrochloride
  • camylofin dihydrochloride
  • Molecular weight: 320.48
  • Formula: C19H32N2O2
  • CLOGP: 4.72
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 41.57
  • ALOGS: -3.68
  • ROTB: 12

Drug dosage:

DoseUnitRoute
0.20 g O
0.20 g R

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A03AA03 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Synthetic anticholinergics, esters with tertiary amino group
ATC A03DA05 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
ANTISPASMODICS IN COMBINATION WITH ANALGESICS
Synthetic anticholinergic agents in combination with analgesics
MeSH PA D010276 Parasympatholytics
MeSH PA D018373 Peripheral Nervous System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.1 Basic
pKa2 4.06 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Solute carrier family 22 member 1 Transporter IC50 5.04 CHEMBL

External reference:

IDSource
D01759 KEGG_DRUG
20136 RXNORM
C0054568 UMLSCUI
CHEBI:95216 CHEBI
CHEMBL253592 ChEMBL_ID
DB13738 DRUGBANK_ID
C004644 MESH_SUPPLEMENTAL_RECORD_UI
5902 PUBCHEM_CID
1182 INN_ID
5892-41-1 SECONDARY_CAS_RN
340B6Q764V UNII
005296 NDDF
005297 NDDF

Pharmaceutical products:

None