difemerine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
spasmolytics with a papaverine-like action 877 80387-96-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • difemerine hydrochloride
  • difemerin
  • luostyl
  • difemerine
  • difemerine HCl
  • Molecular weight: 327.42
  • Formula: C20H25NO3
  • CLOGP: 3.41
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 49.77
  • ALOGS: -3.53
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC A03AA09 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Synthetic anticholinergics, esters with tertiary amino group

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.84 acidic
pKa2 7.9 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0612470 UMLSCUI
D07079 KEGG_DRUG
00JM91Q28F UNII
70280-88-5 SECONDARY_CAS_RN
163406 RXNORM
005404 NDDF
2174 INN_ID
CHEBI:135397 CHEBI
165124 PUBCHEM_CID
C028777 MESH_SUPPLEMENTAL_RECORD_UI
DB13380 DRUGBANK_ID
CHEMBL3301670 ChEMBL_ID
CHEMBL3304486 ChEMBL_ID

Pharmaceutical products:

None