dicycloverine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
spasmolytics with a papaverine-like action	868	77-19-0

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: dicymine dicycloverine hydrochloride dicycloverine dicyclomine dicycloverin dicyclomine hydrochloride dicyclomine HCl	A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms. Molecular weight: 309.49 Formula: C19H35NO2 CLOGP: 6.14 LIPINSKI: 1 HAC: 3 HDO: 0 TPSA: 29.54 ALOGS: -4.98 ROTB: 8 Status: OFP Legend: OFP - off patent OFM - off market ONP - on patent

Molecule

Description

Molfile Inchi Smiles

Synonyms:

dicymine
dicycloverine hydrochloride
dicycloverine
dicyclomine
dicycloverin
dicyclomine hydrochloride
dicyclomine HCl

A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.

Molecular weight: 309.49
Formula: C19H35NO2
CLOGP: 6.14
LIPINSKI: 1
HAC: 3
HDO: 0
TPSA: 29.54
ALOGS: -4.98
ROTB: 8

Status: OFP

Legend:
OFP - off patent
OFM - off market
ONP - on patent

Drug dosage:

Dose	Unit	Route
80	mg	O
80	mg	P

ADMET properties:

Property	Value	Reference
MRTD (Maximum Recommended Therapeutic Daily Dose)	4.30 µM/kg/day	Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
S (Water solubility)	50 mg/mL	Bocci G, Oprea TI, Benet LZ
BDDCS (Biopharmaceutical Drug Disposition Classification System)	1	Bocci G, Oprea TI, Benet LZ

Approvals:

Date	Agency	Company	Orphan
May 11, 1950	FDA	FOREST LABS INC

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Cholecystitis chronic	201.81	12.41	97	28600	10264	63450061
Biliary dyskinesia	107.43	12.41	42	28655	2687	63457638
Anxiety	92.58	12.41	261	28436	217280	63243045
Abdominal pain	82.96	12.41	306	28391	293150	63167175
Gallbladder disorder	81.85	12.41	68	28629	18774	63441551
Contraindicated product administered	81.72	12.41	4	28693	217644	63242681
Synovitis	65.46	12.41	5	28692	186913	63273412
Maternal exposure during pregnancy	64.38	12.41	11	28686	220051	63240274
Glossodynia	59.35	12.41	6	28691	178870	63281455
Drug intolerance	56.31	12.41	35	28662	308626	63151699
Diarrhoea	51.09	12.41	520	28177	714846	62745479
Rhinalgia	50.48	12.41	21	28676	1578	63458747
Drug ineffective	50.33	12.41	273	28424	1044492	62415833
Vulvovaginal burning sensation	48.02	12.41	22	28675	2087	63458238
Treatment failure	46.43	12.41	16	28681	199027	63261298
Depression	45.02	12.41	192	28505	196300	63264025
Vulvovaginal pruritus	41.80	12.41	23	28674	3220	63457105
Product dose omission issue	41.24	12.41	212	28485	234101	63226224
Arthropathy	39.61	12.41	29	28668	234763	63225562
General physical health deterioration	39.32	12.41	21	28676	201381	63258944
Abdominal pain upper	38.58	12.41	190	28507	206254	63254071
Systemic lupus erythematosus	37.64	12.41	24	28673	208894	63251431
Cholelithiasis	36.85	12.41	69	28628	43856	63416469
Gallbladder injury	36.07	12.41	16	28681	1407	63458918
Rheumatoid arthritis	35.96	12.41	37	28660	253782	63206543
Nausea	35.95	12.41	563	28134	853908	62606417
Wound	34.96	12.41	15	28682	163248	63297077
Joint swelling	33.13	12.41	61	28636	327605	63132720
Paranasal sinus discomfort	32.98	12.41	22	28675	4354	63455971
Colitis ulcerative	32.61	12.41	49	28648	26042	63434283
Emotional distress	32.27	12.41	55	28642	32494	63427831
Urinary tract infection	32.01	12.41	217	28480	264467	63195858
Abdominal pain lower	30.36	12.41	47	28650	25631	63434694
Therapeutic product effect decreased	29.89	12.41	26	28671	193161	63267164
Surgery	29.61	12.41	56	28641	35856	63424469
Helicobacter infection	28.56	12.41	4	28693	92781	63367544
Migraine	28.46	12.41	107	28590	103239	63357086
Therapy partial responder	27.88	12.41	29	28668	10629	63449696
Diverticulitis	26.99	12.41	57	28640	39500	63420825
Hepatic enzyme increased	26.98	12.41	31	28666	202297	63258028
Biliary colic	26.82	12.41	18	28679	3599	63456726
Gallbladder hypofunction	26.71	12.41	10	28687	568	63459757
Abdominal distension	26.66	12.41	93	28604	86522	63373803
Pre-existing condition improved	26.32	12.41	25	28672	8219	63452106
Constipation	25.75	12.41	182	28515	224761	63235564
Intestinal obstruction	25.25	12.41	48	28649	30851	63429474
Nasal dryness	25.19	12.41	19	28678	4562	63455763
Fungal infection	25.00	12.41	53	28644	36821	63423504
Palpitations	24.88	12.41	109	28588	112661	63347664
Flatulence	24.84	12.41	51	28646	34651	63425674
Chest pain	24.30	12.41	174	28523	215785	63244540
Increased appetite	23.06	12.41	25	28672	9605	63450720
Thrombocytopenia	22.59	12.41	21	28676	151136	63309189
Infusion site pruritus	22.58	12.41	20	28677	6015	63454310
Nasal discomfort	22.39	12.41	18	28679	4742	63455583
Infusion site erythema	22.35	12.41	27	28670	11652	63448673
Alopecia	22.33	12.41	78	28619	337458	63122867
Small intestinal obstruction	22.29	12.41	34	28663	18303	63442022
Poor peripheral circulation	21.62	12.41	16	28681	3733	63456592
Injection site extravasation	21.26	12.41	23	28674	8818	63451507
Neutropenia	21.05	12.41	29	28668	174976	63285349
Stress	19.71	12.41	71	28626	67096	63393229
Muscle injury	19.69	12.41	3	28694	65342	63394983
Folliculitis	19.51	12.41	4	28693	70313	63390012
Muscle spasms	19.44	12.41	129	28568	156021	63304304
Cholecystectomy	19.33	12.41	24	28673	10653	63449672
Scleritis	19.26	12.41	16	28681	4412	63455913
Suicidal ideation	19.19	12.41	67	28630	62354	63397971
Bronchitis	18.55	12.41	108	28589	124827	63335498
Exposure during pregnancy	18.48	12.41	26	28671	155521	63304804
C-reactive protein increased	18.29	12.41	10	28687	94697	63365628
Vascular access site pain	18.20	12.41	5	28692	103	63460222
Headache	18.02	12.41	393	28304	632848	62827477
Clostridium difficile infection	18.01	12.41	41	28656	29881	63430444
Pancytopenia	17.63	12.41	11	28686	96922	63363403
Colitis	17.51	12.41	55	28642	48473	63411852
Psychological trauma	17.40	12.41	9	28688	1112	63459213
Anhedonia	17.25	12.41	23	28674	10951	63449374
Sinus congestion	17.14	12.41	30	28667	18093	63442232
Impaired gastric emptying	16.77	12.41	22	28675	10310	63450015
Weight decreased	16.74	12.41	195	28502	276603	63183722
Upper-airway cough syndrome	16.54	12.41	23	28674	11395	63448930
Pancreatitis	16.26	12.41	54	28643	49001	63411324
Illness	16.25	12.41	54	28643	49005	63411320
Interstitial lung disease	16.21	12.41	4	28693	61904	63398421
Neck pain	16.05	12.41	68	28629	69250	63391075
Chronic sinusitis	15.88	12.41	24	28673	12819	63447506
Nasal congestion	15.66	12.41	65	28632	65595	63394730
Injury	15.54	12.41	70	28627	73177	63387148
Haematochezia	15.20	12.41	56	28641	53488	63406837
Irritable bowel syndrome	14.76	12.41	75	28622	82337	63377988
Pain	14.68	12.41	438	28259	740190	62720135
Vitamin D deficiency	14.46	12.41	24	28673	13868	63446457
Cholesterosis	14.45	12.41	6	28691	449	63459876
Aphthous ulcer	14.41	12.41	24	28673	13914	63446411
Somnambulism	14.35	12.41	15	28682	5528	63454797
Hypoaesthesia	14.18	12.41	127	28570	168266	63292059
Crying	14.06	12.41	32	28665	23311	63437014
Tonsillitis fungal	13.88	12.41	3	28694	21	63460304
Intestinal mucosal hypertrophy	13.83	12.41	5	28692	257	63460068
Intervertebral disc degeneration	13.55	12.41	25	28672	15707	63444618
Back pain	13.35	12.41	180	28517	263965	63196360
Vision blurred	13.34	12.41	79	28618	91845	63368480
Blister	13.24	12.41	24	28673	129790	63330535
Hyponatraemia	12.99	12.41	19	28678	111881	63348444
Oropharyngeal pain	12.94	12.41	80	28617	94407	63365918
Infusion related reaction	12.92	12.41	62	28635	245459	63214866
Febrile neutropenia	12.90	12.41	21	28676	118428	63341897
Diabetic neuropathy	12.61	12.41	12	28685	3952	63456373

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Irritable bowel syndrome	33.13	15.56	15	6060	3628	34947228
Diarrhoea	31.28	15.56	142	5933	389770	34561086
Abdominal pain	29.35	15.56	78	5997	163540	34787316
Hypogonadism	26.08	15.56	11	6064	2244	34948612
Alkalosis hypochloraemic	21.93	15.56	6	6069	326	34950530
Aplastic anaemia	21.69	15.56	16	6059	9700	34941156
Colitis ulcerative	19.80	15.56	19	6056	16501	34934355
Nausea	18.31	15.56	111	5964	339797	34611059
Apathy	16.80	15.56	12	6063	6920	34943936
Rectourethral fistula	16.39	15.56	3	6072	24	34950832
Intestinal obstruction	16.35	15.56	20	6055	22802	34928054
Weight decreased	16.17	15.56	67	6008	176234	34774622

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Cholecystitis chronic	199.26	12.75	86	26024	9820	79708458
Biliary dyskinesia	108.02	12.75	38	26072	2507	79715771
Gallbladder disorder	88.13	12.75	63	26047	19277	79699001
Abdominal pain	82.98	12.75	298	25812	389271	79329007
Anxiety	73.67	12.75	213	25897	248299	79469979
Vulvovaginal burning sensation	60.53	12.75	22	26088	1595	79716683
Diarrhoea	58.99	12.75	490	25620	879999	78838279
Rhinalgia	52.39	12.75	22	26088	2345	79715933
Vulvovaginal pruritus	46.92	12.75	21	26089	2612	79715666
Product dose omission issue	44.06	12.75	179	25931	247358	79470920
Abdominal pain upper	44.00	12.75	167	25943	223652	79494626
Gallbladder injury	39.78	12.75	15	26095	1206	79717072
Paranasal sinus discomfort	39.16	12.75	22	26088	4434	79713844
Pain	38.45	12.75	375	25735	703427	79014851
Colitis ulcerative	38.44	12.75	52	26058	34690	79683588
Synovitis	37.99	12.75	3	26107	150731	79567547
Nausea	37.27	12.75	477	25633	956719	78761559
General physical health deterioration	34.45	12.75	24	26086	275214	79443064
Abdominal pain lower	34.30	12.75	47	26063	31735	79686543
Neutropenia	33.55	12.75	27	26083	287683	79430595
Cholelithiasis	32.09	12.75	60	26050	52604	79665674
Drug intolerance	31.79	12.75	24	26086	264095	79454183
Clostridium difficile infection	31.65	12.75	53	26057	42632	79675646
Emotional distress	31.49	12.75	51	26059	39918	79678360
Urinary tract infection	30.30	12.75	173	25937	274339	79443939
Headache	29.84	12.75	336	25774	653436	79064842
Nasal dryness	28.30	12.75	18	26092	4545	79713733
Migraine	27.83	12.75	77	26033	87416	79630862
Diverticulitis	27.57	12.75	52	26058	45884	79672394
Irritable bowel syndrome	27.40	12.75	62	26048	62179	79656099
Injection site extravasation	25.78	12.75	23	26087	9646	79708632
Nasal discomfort	25.29	12.75	18	26092	5465	79712813
Chest pain	24.92	12.75	168	25942	282136	79436142
Depression	24.82	12.75	138	25972	216652	79501626
Surgery	24.71	12.75	41	26069	32725	79685553
Cholecystectomy	24.29	12.75	22	26088	9410	79708868
Upper-airway cough syndrome	23.89	12.75	24	26086	11669	79706609
Palpitations	23.65	12.75	93	26017	126517	79591761
Increased appetite	23.41	12.75	24	26086	11954	79706324
Neck pain	22.64	12.75	65	26045	75352	79642926
Gallbladder hypofunction	22.57	12.75	8	26102	539	79717739
Vision blurred	22.44	12.75	81	26029	105817	79612461
Hypogonadism	22.02	12.75	11	26099	1749	79716529
Interstitial lung disease	21.90	12.75	5	26105	112595	79605683
Small intestinal obstruction	21.75	12.75	35	26075	27237	79691041
Drug interaction	21.63	12.75	67	26043	415116	79303162
Flatulence	21.59	12.75	45	26065	42679	79675599
Pericarditis	21.57	12.75	4	26106	104232	79614046
Thrombocytopenia	21.02	12.75	34	26076	265225	79453053
Pain in extremity	20.69	12.75	196	25914	364342	79353936
Injury	20.61	12.75	64	26046	77432	79640846
Biliary colic	20.60	12.75	14	26096	3948	79714330
Drug ineffective	20.56	12.75	241	25869	1080672	78637606
Multiple organ dysfunction syndrome	20.30	12.75	7	26103	120239	79598039
Intestinal obstruction	20.22	12.75	44	26066	42976	79675302
Abdominal distension	20.06	12.75	85	26025	119565	79598713
Treatment failure	19.86	12.75	16	26094	170470	79547808
Maternal exposure during pregnancy	19.75	12.75	10	26100	136528	79581750
Pancreatitis	19.52	12.75	58	26052	68517	79649761
Constipation	19.05	12.75	158	25952	282892	79435386
Bronchitis	19.02	12.75	89	26021	130555	79587723
Hyperkalaemia	18.73	12.75	7	26103	114391	79603887
Cardiac failure	18.71	12.75	14	26096	154828	79563450
Vascular access site pain	18.69	12.75	5	26105	130	79718148
Parotitis	18.42	12.75	11	26099	2483	79715795
Chronic sinusitis	18.36	12.75	22	26088	13004	79705274
Aphthous ulcer	18.26	12.75	25	26085	16864	79701414
Psychological trauma	18.22	12.75	9	26101	1397	79716881
Sinus congestion	17.91	12.75	27	26083	19869	79698409
Infusion site pruritus	17.81	12.75	13	26097	4105	79714173
Glossodynia	17.47	12.75	6	26104	103331	79614947
Nasal congestion	17.46	12.75	60	26050	76492	79641786
Oropharyngeal pain	17.04	12.75	76	26034	109277	79609001
Fungal infection	16.63	12.75	40	26070	41708	79676570
Injection site pain	16.44	12.75	85	26025	129753	79588525
Crying	16.27	12.75	28	26082	23015	79695263
Stress	16.11	12.75	60	26050	79552	79638726
Pancreatitis acute	16.11	12.75	44	26066	49560	79668718
Proctalgia	15.95	12.75	18	26092	9983	79708295
Alkalosis hypochloraemic	15.73	12.75	6	26104	498	79717780
Impaired gastric emptying	15.45	12.75	18	26092	10335	79707943
Joint dislocation	15.27	12.75	23	26087	16916	79701362
Discharge	15.05	12.75	8	26102	1446	79716832
Illness	14.85	12.75	41	26069	46470	79671808
Tonsillitis fungal	14.84	12.75	3	26107	21	79718257
Presbyopia	14.73	12.75	6	26104	592	79717686
Colitis	14.63	12.75	55	26055	73252	79645026
Back pain	14.58	12.75	158	25952	304022	79414256
Pre-existing condition improved	14.37	12.75	13	26097	5550	79712728
Muscle spasms	14.23	12.75	102	26008	174628	79543650
Oral herpes	13.96	12.75	29	26081	27425	79690853
Intestinal mucosal hypertrophy	13.95	12.75	5	26105	348	79717930
Hip fracture	13.93	12.75	31	26079	30730	79687548
Hepatic enzyme increased	13.91	12.75	24	26086	182586	79535692
Helicobacter infection	13.74	12.75	3	26107	69701	79648577
Rheumatoid arthritis	13.62	12.75	30	26080	208440	79509838
Suicidal ideation	13.39	12.75	55	26055	76285	79641993
Pancytopenia	13.35	12.75	21	26089	165724	79552554
Increased upper airway secretion	13.30	12.75	11	26099	4166	79714112
Anhedonia	13.10	12.75	20	26090	14878	79703400
Device issue	13.05	12.75	28	26082	27080	79691198
C-reactive protein increased	12.80	12.75	14	26096	129013	79589265

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A03AA07	ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS Synthetic anticholinergics, esters with tertiary amino group
FDA MoA	N0000175370	Cholinergic Antagonists
FDA EPC	N0000175574	Anticholinergic
CHEBI has role	CHEBI:48876	muscarinic antagonists
CHEBI has role	CHEBI:50370	parasympatholytics
CHEBI has role	CHEBI:53784	antispasmodics
MeSH PA	D018678	Cholinergic Agents
MeSH PA	D018680	Cholinergic Antagonists
MeSH PA	D018727	Muscarinic Antagonists
MeSH PA	D018377	Neurotransmitter Agents
MeSH PA	D010276	Parasympatholytics
MeSH PA	D018373	Peripheral Nervous System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Irritable bowel syndrome	indication	10743008	DOID:9778
Calculus in biliary tract	off-label use	266474003
Brain damage	contraindication	2470005
Tachyarrhythmia	contraindication	6285003
Suicidal thoughts	contraindication	6471006
Urinary tract obstruction	contraindication	7163005	DOID:5200
Alcoholism	contraindication	7200002
Hyperammonemia	contraindication	9360008
Hepatic encephalopathy	contraindication	13920009	DOID:13413
Severe chronic ulcerative colitis	contraindication	14311001
Toxic megacolon	contraindication	28536002	DOID:1770
Atony of colon	contraindication	29479008
Hyperthyroidism	contraindication	34486009	DOID:7998
Depressive disorder	contraindication	35489007
Hypertensive disorder	contraindication	38341003	DOID:10763
Complete trisomy 21 syndrome	contraindication	41040004	DOID:14250
Achalasia of esophagus	contraindication	45564002	DOID:9164
Chronic heart failure	contraindication	48447003
Paralytic ileus	contraindication	55525008	DOID:8442
Peptic reflux disease	contraindication	57643001
Hepatic failure	contraindication	59927004
Ulcerative colitis	contraindication	64766004	DOID:8577
Poisoning by phenobarbital	contraindication	64921004
Drug AND/OR toxin-induced diarrhea	contraindication	65979008
Substance abuse	contraindication	66214007
Hepatic coma	contraindication	72836002	DOID:12550
Sleep apnea	contraindication	73430006	DOID:0050847
Spastic paralysis	contraindication	78403003
Disturbance of salivary secretion	contraindication	78948009
Kidney disease	contraindication	90708001	DOID:557
Myasthenia gravis	contraindication	91637004	DOID:437
Gastrointestinal obstruction	contraindication	126765001
Autonomic dysreflexia	contraindication	129618003
Bleeding	contraindication	131148009
Disease of liver	contraindication	235856003	DOID:409
Bladder outflow obstruction	contraindication	236645006
Benign prostatic hyperplasia	contraindication	266569009
Dyspnea	contraindication	267036007
Retention of urine	contraindication	267064002
Anemia	contraindication	271737000	DOID:2355
Pregnancy, function	contraindication	289908002
Thrombocytopenic disorder	contraindication	302215000	DOID:1588
Neutropenic disorder	contraindication	303011007	DOID:1227
Angle-closure glaucoma	contraindication	392291006	DOID:13550
Gastric ulcer	contraindication	397825006	DOID:10808
Breastfeeding (mother)	contraindication	413712001
Chronic lung disease	contraindication	413839001
Disorder of coronary artery	contraindication	414024009
Porphyria	contraindication	418470004
Fever greater than 100.4 Fahrenheit	contraindication	426000000

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	8.41	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Bioact source	MoA source
Muscarinic acetylcholine receptor M3	GPCR	P20309	ACM3_HUMAN	ANTAGONIST	Ki	9.03	DRUG MATRIX	CHEMBL
Muscarinic acetylcholine receptor M1	GPCR	P11229	ACM1_HUMAN	ANTAGONIST	Ki	9.08	DRUG MATRIX	CHEMBL
5-hydroxytryptamine receptor 2A	GPCR	P28223	5HT2A_HUMAN		Ki	7.16	DRUG MATRIX
5-hydroxytryptamine receptor 2B	GPCR	P41595	5HT2B_HUMAN		Ki	6.08	DRUG MATRIX
5-hydroxytryptamine receptor 2C	GPCR	P28335	5HT2C_HUMAN		Ki	6.61	DRUG MATRIX
5-hydroxytryptamine receptor 6	GPCR	P50406	5HT6R_HUMAN		Ki	5.85	DRUG MATRIX
D(3) dopamine receptor	GPCR	P35462	DRD3_HUMAN		Ki	6.39	DRUG MATRIX
Histamine H2 receptor	GPCR	P25021	HRH2_HUMAN		Ki	5.80	DRUG MATRIX
Muscarinic acetylcholine receptor M2	GPCR	P08172	ACM2_HUMAN	ANTAGONIST	Ki	6.60	IUPHAR
Muscarinic acetylcholine receptor M4	GPCR	P08173	ACM4_HUMAN		Ki	9.39	DRUG MATRIX
Muscarinic acetylcholine receptor M5	GPCR	P08912	ACM5_HUMAN		Ki	8.77	DRUG MATRIX
Sigma non-opioid intracellular receptor 1	Membrane receptor	Q99720	SGMR1_HUMAN		Ki	8.69	DRUG MATRIX
Sodium channel alpha subunits; brain (Types I, II, III)	Ion channel	P35498 Q99250 Q9NY46	SCN1A_HUMAN SCN2A_HUMAN SCN3A_HUMAN		IC50	4.55	CHEMBL
Potassium voltage-gated channel subfamily H member 2	Ion channel	Q12809	KCNH2_HUMAN		Ki	4.77	DRUG MATRIX
Membrane-associated progesterone receptor component 1	Membrane receptor		PGRC1_RAT		IC50	6.33	DRUG MATRIX
SMR1-alpha2	Unclassified		P70676_RAT		Ki	6.54	DRUG MATRIX
Muscarinic acetylcholine receptor M2	GPCR		ACM2_RAT		Ki	7.33	CHEMBL
Muscarinic acetylcholine receptor M1	GPCR		ACM1_RAT		Ki	8.61	CHEMBL

External reference:

ID	Source
4017870	VUID
N0000179550	NUI
D00717	KEGG_DRUG
67-92-5	SECONDARY_CAS_RN
152021	RXNORM
4017870	VANDF
4019716	VANDF
C0012125	UMLSCUI
CHEBI:4514	CHEBI
CHEMBL1123	ChEMBL_ID
CHEMBL1200479	ChEMBL_ID
DB00804	DRUGBANK_ID
355	IUPHAR_LIGAND_ID
3042	PUBCHEM_CID
158	MMSL
4587	MMSL
d00999	MMSL
001758	NDDF
004711	NDDF
372732007	SNOMEDCT_US
41493007	SNOMEDCT_US
71043005	SNOMEDCT_US
D004025	MESH_DESCRIPTOR_UI
619	INN_ID
4KV4X8IF6V	UNII

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0054-0622	SOLUTION	10 mg	ORAL	ANDA	24 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0054-0622	SOLUTION	10 mg	ORAL	ANDA	24 sections
Dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0054-0748	CAPSULE	10 mg	ORAL	ANDA	25 sections
Dicyclomine	HUMAN PRESCRIPTION DRUG LABEL	1	0143-1227	TABLET	20 mg	ORAL	ANDA	26 sections
Dicyclomine	HUMAN PRESCRIPTION DRUG LABEL	1	0143-1227	TABLET	20 mg	ORAL	ANDA	26 sections
Dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0143-3126	CAPSULE	10 mg	ORAL	ANDA	26 sections
Dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0143-3126	CAPSULE	10 mg	ORAL	ANDA	26 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0378-1610	CAPSULE	10 mg	ORAL	ANDA	27 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0378-1610	CAPSULE	10 mg	ORAL	ANDA	27 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0378-1620	TABLET	20 mg	ORAL	ANDA	27 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0378-1620	TABLET	20 mg	ORAL	ANDA	27 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0440-7384	CAPSULE	10 mg	ORAL	ANDA	26 sections
Dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0517-1980	INJECTION, SOLUTION	20 mg	INTRAMUSCULAR	ANDA	24 sections
Dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0517-1980	INJECTION, SOLUTION	20 mg	INTRAMUSCULAR	ANDA	24 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0527-0586	CAPSULE	10 mg	ORAL	ANDA	26 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0527-1282	TABLET	20 mg	ORAL	ANDA	26 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0591-0794	CAPSULE	10 mg	ORAL	ANDA	25 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0591-0795	TABLET	20 mg	ORAL	ANDA	25 sections
dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0603-1161	SOLUTION	10 mg	ORAL	ANDA	26 sections
Dicyclomine	HUMAN PRESCRIPTION DRUG LABEL	1	0615-0327	CAPSULE	10 mg	ORAL	ANDA	26 sections
Dicyclomine	HUMAN PRESCRIPTION DRUG LABEL	1	0615-0327	CAPSULE	10 mg	ORAL	ANDA	26 sections
Dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0615-8483	CAPSULE	10 mg	ORAL	ANDA	25 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0641-6173	INJECTION	10 mg	INTRAMUSCULAR	ANDA	25 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0641-6173	INJECTION	10 mg	INTRAMUSCULAR	ANDA	25 sections
Dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0832-6052	TABLET	20 mg	ORAL	ANDA	30 sections
Dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0832-6053	CAPSULE	10 mg	ORAL	ANDA	30 sections
Dicyclomine hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0904-6969	CAPSULE	10 mg	ORAL	ANDA	26 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0904-6987	CAPSULE	10 mg	ORAL	ANDA	26 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	0904-6988	TABLET	20 mg	ORAL	ANDA	26 sections
Dicyclomine Hydrochloride	HUMAN PRESCRIPTION DRUG LABEL	1	10135-520	CAPSULE	10 mg	ORAL	ANDA	25 sections