Stem definition | Drug id | CAS RN |
---|---|---|
2748 | 39133-31-8 |
Dose | Unit | Route |
---|---|---|
0.60 | g | O |
None
None
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hyponatraemia | 110.74 | 26.83 | 66 | 2735 | 111834 | 63374387 |
Necrosis ischaemic | 105.46 | 26.83 | 20 | 2781 | 840 | 63485381 |
Pneumonia streptococcal | 90.61 | 26.83 | 20 | 2781 | 1791 | 63484430 |
Beta haemolytic streptococcal infection | 88.38 | 26.83 | 20 | 2781 | 2005 | 63484216 |
Coma | 61.04 | 26.83 | 37 | 2764 | 64327 | 63421894 |
Colitis microscopic | 58.13 | 26.83 | 20 | 2781 | 9319 | 63476902 |
Acute kidney injury | 57.30 | 26.83 | 64 | 2737 | 263351 | 63222870 |
Drug reaction with eosinophilia and systemic symptoms | 55.70 | 26.83 | 28 | 2773 | 33808 | 63452413 |
Interstitial lung disease | 54.64 | 26.83 | 34 | 2767 | 61874 | 63424347 |
Poisoning deliberate | 54.55 | 26.83 | 20 | 2781 | 11198 | 63475023 |
Fall | 54.38 | 26.83 | 76 | 2725 | 392258 | 63093963 |
Septic shock | 47.49 | 26.83 | 32 | 2769 | 66597 | 63419624 |
Hypokalaemia | 47.19 | 26.83 | 38 | 2763 | 103766 | 63382455 |
Rash maculo-papular | 39.97 | 26.83 | 22 | 2779 | 31874 | 63454347 |
Colitis | 38.68 | 26.83 | 25 | 2776 | 48503 | 63437718 |
Toxic skin eruption | 38.01 | 26.83 | 16 | 2785 | 12869 | 63473352 |
Cardio-respiratory arrest | 36.16 | 26.83 | 26 | 2775 | 59933 | 63426288 |
Granulomatous liver disease | 35.66 | 26.83 | 8 | 2793 | 770 | 63485451 |
Hypophosphataemia | 33.07 | 26.83 | 14 | 2787 | 11412 | 63474809 |
Transverse sinus thrombosis | 32.59 | 26.83 | 7 | 2794 | 551 | 63485670 |
Superior sagittal sinus thrombosis | 30.15 | 26.83 | 7 | 2794 | 784 | 63485437 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Wrong patient received product | 36.93 | 29.00 | 11 | 1876 | 2643 | 34952401 |
Acute kidney injury | 34.57 | 29.00 | 60 | 1827 | 304928 | 34650116 |
Encephalopathy | 31.39 | 29.00 | 21 | 1866 | 35298 | 34919746 |
Tumour necrosis | 30.05 | 29.00 | 8 | 1879 | 1280 | 34953764 |
Mydriasis | 29.52 | 29.00 | 12 | 1875 | 7225 | 34947819 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Necrosis ischaemic | 94.77 | 23.89 | 20 | 4717 | 1070 | 79738581 |
Hyponatraemia | 91.01 | 23.89 | 79 | 4658 | 177769 | 79561882 |
Beta haemolytic streptococcal infection | 81.74 | 23.89 | 20 | 4717 | 2077 | 79737574 |
Acute kidney injury | 78.86 | 23.89 | 123 | 4614 | 519281 | 79220370 |
Pneumonia streptococcal | 76.39 | 23.89 | 20 | 4717 | 2725 | 79736926 |
Coma | 75.52 | 23.89 | 56 | 4681 | 100593 | 79639058 |
Colitis microscopic | 49.53 | 23.89 | 20 | 4717 | 10748 | 79728903 |
Poisoning deliberate | 47.71 | 23.89 | 23 | 4714 | 18805 | 79720846 |
Drug reaction with eosinophilia and systemic symptoms | 44.27 | 23.89 | 34 | 4703 | 64210 | 79675441 |
Rash maculo-papular | 41.56 | 23.89 | 31 | 4706 | 56047 | 79683604 |
Toxic skin eruption | 41.19 | 23.89 | 22 | 4715 | 22271 | 79717380 |
Fall | 39.12 | 23.89 | 88 | 4649 | 487541 | 79252110 |
Interstitial lung disease | 36.56 | 23.89 | 39 | 4698 | 112561 | 79627090 |
Encephalopathy | 36.53 | 23.89 | 31 | 4706 | 67366 | 79672285 |
Septic shock | 35.48 | 23.89 | 40 | 4697 | 122761 | 79616890 |
Hypomagnesaemia | 34.91 | 23.89 | 26 | 4711 | 46885 | 79692766 |
Hypocalcaemia | 33.47 | 23.89 | 26 | 4711 | 49898 | 79689753 |
Inappropriate antidiuretic hormone secretion | 32.58 | 23.89 | 20 | 4717 | 26293 | 79713358 |
Wrong patient received product | 29.89 | 23.89 | 11 | 4726 | 4607 | 79735044 |
Transverse sinus thrombosis | 29.29 | 23.89 | 7 | 4730 | 658 | 79738993 |
Febrile bone marrow aplasia | 27.34 | 23.89 | 14 | 4723 | 13006 | 79726645 |
Hypokalaemia | 27.30 | 23.89 | 38 | 4699 | 144002 | 79595649 |
Hypophosphataemia | 26.88 | 23.89 | 16 | 4721 | 19897 | 79719754 |
Cholestasis | 26.27 | 23.89 | 23 | 4714 | 52086 | 79687565 |
Tumour necrosis | 26.12 | 23.89 | 8 | 4729 | 1914 | 79737737 |
Superior sagittal sinus thrombosis | 26.03 | 23.89 | 7 | 4730 | 1056 | 79738595 |
Miosis | 24.80 | 23.89 | 14 | 4723 | 15775 | 79723876 |
Granulomatous liver disease | 24.46 | 23.89 | 7 | 4730 | 1326 | 79738325 |
None
Source | Code | Description |
---|---|---|
ATC | A03AA05 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS Synthetic anticholinergics, esters with tertiary amino group |
MeSH PA | D005765 | Gastrointestinal Agents |
MeSH PA | D010276 | Parasympatholytics |
MeSH PA | D018373 | Peripheral Nervous System Agents |
None
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 7.6 | Basic |
None
None
None
ID | Source |
---|---|
D01500 | KEGG_DRUG |
34140-59-5 | SECONDARY_CAS_RN |
C0041023 | UMLSCUI |
CHEBI:32261 | CHEBI |
CHEMBL190044 | ChEMBL_ID |
DB09089 | DRUGBANK_ID |
D014287 | MESH_DESCRIPTOR_UI |
5573 | PUBCHEM_CID |
2773 | INN_ID |
QZ1OJ92E5R | UNII |
10819 | RXNORM |
003502 | NDDF |
003503 | NDDF |
698184001 | SNOMEDCT_US |
703719009 | SNOMEDCT_US |
None